To explore the bidirectional association between metabolic syndrome(MS) and depression in middle-aged and elderly adults in China.

This study used participants aged 45 and above from publicly available longitudinal data from the China Health and Retirement Longitudinal Study(CHARLS) from 2011 to 2018. The baseline was based on 2011 data. Stage I studied the longitudinal association of baseline MS with follow-up depression, while Stage II studied the association of baseline depression with follow-up MS. Stage III further investigated the bidirectional association between MS and depression using a cross-lagged panel model, and the follow-up data for all three stages used 2015 data including blood routine examination and physical examinations.

There was a bidirectional association between the two diseases. The baseline MS and its components showed a positive correlation with the follow-up depression(β=0.052, P<0.01), and vice versa(β=0.305, P<0.01), but there were differences in gender subgroups.

There is a bidirectional correlation between MS and its components and depression in the middle-aged and elderly population in China. We should identify, monitor, and intervene in early MS and depression.

To study the relationship between the cardiometabolic index (CMI) and hyperuricemia (HUA) in Guizhou minorities.

Based on the "China Multi-ethnic Cohort Study", 16 630 Miao, Dong and Bouyei population aged 30 to 79 years were included in the study. Logistic regression model was used to analyze the association between CMI and HUA, restricted cubic spline was used to analyze the dose-response relationship between CMI and HUA, and ROC curve was used to analyze the predictive value of CMI for HUA.

The overall detection rate of HUA was 22.8%, and those of Miao, Dong and Bouyei nationalities were 24.4%, 25.2% and 18.5%, respectively. In the total population, Miao, Dong and Bouyei populations, after adjusting for covariates, compared with Q1, the ORs for HUA were 4.39 (95%CI: 3.76-5.12), 3.96 (95%CI: 3.03-5.18), 4.28 (95%CI: 3.36-5.46), and 5.55 (95%CI: 4.08-7.54) in CMI Q4 group, respectively. There was a non-linear dose-response relationship between CMI and risk of HUA (P for nonlinear < 0.001). ROC curve analysis showed that, the area under the curve (the best cut-off value, sensitivity and specificity) of CMI for predicting the risk of HUA in the total population, Miao, Dong and Bouyei populations were 0.742 (0.641, 68.3%,68.8%), 0.724 (0.651, 63.8%, 70.8%) 0.741 (0.654, 68.5%, 68.1%), 0.775 (0.555, 68.8%, 73.0%).

CMI is associated with the increased risk of HUA in different ethnic populations, and can be used as an indicator for predicting HUA in ethnic minority populations in Guizhou province.

To explore the prevalence and influencing factors of depression among the elderly in rural areas of Sichuan Province.

By using the method of multi-stage sampling, a questionnaire survey was conducted among 606 rural elderly persons in Sichuan from July to August, 2022. Chi-square test and multivariate logistic regression analysis were used to explore the influencing factors of depression.

The average score of depression in the rural elderly was (3.79± 3.21) points, 85 people had depressive symptoms, and the prevalence rate of depressive symptoms was 14.0%. Multivariate logistic regression analysis showed that not seeking medical treatment due to economic difficulties in the past year (OR=10.140, 95%CI: 3.347-30.716), hospitalization in the past year (OR=5.229, 95%CI: 2.789-9.801), self-rated health fair or below( poor self-rated health: OR=20.301, 95%CI: 7.666-53.761; fair self-rated health: OR=5.912, 95%CI: 2.729-12.807) and childless (OR=8.495, 95%CI: 1.747-41.313) were risk factors for depressive symptoms in the rural elderly (P<0.05). Living with a spouse (OR=0.321, 95%CI: 0.116-0.888) and high social support (OR=0.505, 95%CI: 0.260-0.982) were protective factors for depressive symptoms in rural elderly (P<0.05).

The depression situation of the elderly in rural areas of Sichuan Province is worrying, which needs to be paid special attention and early intervention, especially for the rural elderly with economic difficulties, poor health status, no children or living alone.

To explore the minimum clinically important difference (MCID) of peptic ulcer scale QLICD-PU (V2.0) among the System of quality of life instruments for chronic diseases.

Using convenience sampling, the questionnaire was administered from March 2013 to August 2014 using the QLICD-PU (V2.0) scale, and the MCIDs were calculatedusing the anchor-based and distribution-based methods, respectively, and analyzed to compare the MCIDs developed by taking the mean, taking the minimum, and taking the maximum methods.

The MCIDs of physical functioning (8.53), psychological functioning (8.45), social functioning (7.61), general module (7.05), specific module (8.82), and overall scale (7.53) obtained by taking the mean method; the MCIDs obtained by taking the minimum method were 5.25, 5.78, 6.16, 4.19, 7.18 and 4.09, respectively; the MCID obtained by taking the maximum method were 11.99, 12.05, 10.09, 9.48, 10.99 and 11.04, respectively.

In this paper, MCID was formulated by using various methods and criteria, which can be chosen by the users according to the situation. MCID can be used to assess the clinical efficacy of patients with peptic ulcers for the application of quality of life. The MCID values formulated can be validated further by clinical practice in subsequent studies.

To understand the prevalence and trend incidence of neural tube defects (NTDs) in Chongqing from 2007 to 2022, and to provide evidence for comprehensive prevention and control measures.

Based on hospital monitoring data, 185 children with NTDs monitored by all birth defects monitoring institutions in Chongqing City from January 2007 to December 2022 were included in the study. They were grouped by year, perinatal gender, maternal permanent residence (urban/rural), maternal age, different regions, and other categories. Chisquare test was used to analyze the differences in the incidence of severe multiple disabling birth defects in different categories, and linear trend test and Joinpoint regression model were used to analyze the change trend.

From 2007 to 2022, a total of 1 316 934 perinatal births and 185 NTDs were monitored in Chongqing, with an incidence of 1.40/10,000, it was 0.36/10 000(0.00/10 000-2.45/10 000), 0.81/10 000(0.39/10 000-2.42/10 000) and 0.26/10 000(0.00/10 000-2.45/10 000) for anencephaly, spina bifidaand encephalocele respectively. The incidence in rural areas was higher than in urban areas (χ²=11.38, P<0.001). The total incidence of mothers of different age was statistical (χ²=81.71, P<0.001). The annual incidence of NTDs decreased by 84.64% from 2.93/10,000 to 0.45/10,000 during this period. There was a gentle decline from 2007 to 2019 (APC=-10.85) and a rapid decline from 2019 to 2022 (APC=-31.20).

Annual incidence of NTDs in Chongqing was decreasing over the year. NTDs is prevalent at a low level in Chongqing.

To explore the association between metabolic score of insulin resistance (METS-IR) and the risk of Cardiometabolic multimorbidity (CMM) in middle-aged and elderly Chinese.

A population-based cohort study was conducted using data from the China Longitudinal Study of Health and Aging (CHARLS) among Chinese residents aged 45 years or older from 2011 to 2018. Cox proportional hazards regression models were used to calculate Hazard Ratio (HR) and 95% confidence intervals (CI) for the association between METS-IR and new CMM, and stratified analyses were performed in different populations to observe the interaction between covariates and METS-IR. The dose-response relationship between METS-IR and new CMM in different body weight population was observed with restricted cubic spline. Receiver operating characteristic (ROC) curve was constructed to analyze the value of METS-IR in predicting the risk of CMM.

A total of 5 349 subjects were included in this study, and the incidence of CMM was 2.08%. After adjusting for all included covariates, METS-IR as a continuous variable was positively correlated with the risk of CMM (HR: 1.07, 95%CI: 1.05-1.09, P<0.001). As a categorical variable, the highest METS-IR group was still positively associated with the risk of CMM (HR: 3.47, 95%CI: 2.06-5.84, P<0.001). In total participants (P for overall <0.001), normal weight (P for overall = 0.022) and overweight and obese (P for overall = 0.008) populations still had a linear relationship between MET-IR and CMM risk. METS-IR was predictive of CMM risk (AUC: 0.651, 95%CI: 0.598-0.704).

The study finds that METS-IR is positively associated with an increased risk of new CMM in middle-aged and older adults and should be of continued concern in both normal weight and overweight obese people to reduce the risk of CMM.

To investigate the quality of statistical reporting in publications from general medical journals and analyze the influencing factors.

A random sample of 480 original research articles published in 2010 and 2020 was selected from two Medline journals and six Chinese core journals in the field of medicine and health. The quality of statistical reporting was evaluated using a self-developed checklist based on the SAMPL guidelines, ICMJE recommendations, CONSORT, STROBE, and other relevant standards, followed by an analysis of influencing factors.

The overall quality score for statistical reporting in the surveyed general medical journals was 40.0±8.6. The scores for different statistical aspects were as follows: statistical design (43.2±6.8), statistical description (67.0±24.3), t-test (23.6±17.5), ANOVA (26.8±17.2), chi-square test (24.2±13.7), rank-sum test (45.5±18.4), correlation analysis (41.9±13.2), regression analysis (40.5±14.8), and survival analysis (45.6±14.9). Univariate analysis indicated that the overall quality score for statistical reporting in articles published in 2020 was higher than that in 2010 (35.8±7.4 vs. 44.3±7.5, t=-12.510, P<0.001). Multilevel modeling showed that the indexing system, research field, and publication year were the main factors influencing the overall score. Compared to Medline-indexed journals, the overall scores were lower for Chinese core journals. Articles focusing on non-human subjects had lower scores compared to those involving human subjects. Additionally, the overall scores for articles published in 2020 were higher than those in 2010.

The quality of statistical reporting in general medical journals in China has improved over the past decade, but there remains substantial room for further improvement. It is recommended to enhance the promotion of relevant reporting standards.

To construct a postpartum depression risk prediction model for multi-ethnic population in Yunnan Province of China, and identify predictive factors.

Women who were 42 days and within 1 year after childbirth were screened, and the Edinburgh Postnatal Depression Scale (EPDS≥9) was used for postpartum depression. 52 influencing factors from economics, social psychology, obstetrics, neonatology, spouse and family dynamics and other characteristics were included in the survey. A random forest algorithm was employed to construct a predictive model for postnatal depression risk in the multi-ethnic population of Yunnan Province. The model was evaluated on test sets with accuracy, sensitivity, specificity, positive predictive value, negative predictive value, and the area under the receiver operating characteristic curve (Area Under Curve, AUC) to assess its performance.

A total of 459 women were analyzed, with a postpartum depression detection rate of 11.55%. Among them, the detection rates for Han, Zhuang and other ethnic minorities were 7.56%, 13.94% and 13.92%, respectively. The top 14 variables in terms of importance scores were: anxiety, history of previous negative emotions, marital relationship, family support level, physical and mental exhaustion in caring for newborns, pregnancy risk classification, mother-infant rooming-in, feeding mode, education level, spouse’s education level, frequency of nighttime newborn care, ethnicity, parity and age. The accuracy was 92.74%, specificity was 95.50%, sensitivity was 69.23%, positive predictive value was 64.29%, negative predictive value was 96.36%, and the AUC value was 0.925, using Han, Zhuang, and other ethnic minorities as validation sets respectively. The model also demonstrated good stability.

The random forest algorithm-based postpartum depression risk prediction model for the multi-ethnic population in Yunnan performed well, which can be utilized to predict risk factors for postpartum depression among women in minority ethnic areas, thereby facilitating targeted intervention measures.

To explore the impact of passive smoking during pregnancy on neurobehavioral developmental abnormalities in 1-year-old children.

1 363 pairs of mothers and children from the Shenzhen birth Cohort study platform were selected as the research objects. Questionnaire was used to investigate the general demography characteristics and passive smoking of pregnant women during pregnancy, and the age and development process questionnaire (ASQ-3/ASQ: SE) was used to assess the neurobehavioral development of children at one year old. Analyze the impact of passive smoking during pregnancy on neurobehavioral developmental abnormalities in 1-year-old children using a logistic regression model.

Passive smoking during pregnancy had varying degrees of harmful effects on the development of 1-year-old children, except for gross movements. Compared with those without passive smoking, pregnant women with severe passive smoking in early pregnancy had an increased risk of delayed development in communication (OR=1.932, 95%CI: 1.023-3.648), fine motor skills (OR=3.388, 95%CI: 1.232-9.317), problem-solving (OR=3.270, 95%CI: 1.317-7.795), and social emotional development (OR=1.792, 95%CI: 1.159-2.772) among their offspring. In mid-pregnancy, pregnant women who smoke passively had an increased risk of delayed development in communication (OR=1.802, 95%CI: 1.068-3.039) and personal social (OR=1.705, 95%CI: 1.080-2.837) among their offspring, while pregnant women who smoke heavily had an increased risk of delayed development in communication (OR=2.864, 95%CI: 1.322-6.240) and social emotional (OR=1.882, 95%CI: 1.081-3.275) among their offspring. In late pregnancy, pregnant women with severe passive smoking had an increased risk of delayed communication (OR=3.415, 95%CI: 1.366-3.158), fine motor skills (OR=3.976 times, 95%CI: 1.838-13.360), and social emotional development (OR=2.231, 95%CI: 1.234-4.032) in their offspring.

Passive smoking in the early, middle, and late stages of pregnancy can have varying degrees of harmful effects on the neurobehavioral development of offspring at one year old. Suggest relevant departments to increase publicity and education efforts, guide the public to reduce indoor smoking and pay attention to maternal health and early neurobehavioral development in children.

To analyze the epidemiological characteristics of injuries deaths among children and adolescents in Shaanxi Province from 2015 to 2022 and provide insight in formulating interventions to prevent accidental deaths among children and adolescents.

Analyze the distribution of gender, age groups, and cause of death in injury deaths among children and adolescents in Shaanxi Province from 2015 to 2022. χ² test was used to compare the mortality differences between genders, age groups and years. The Joinpoint regression method was used to analyze the trend of child and adolescent mortality. Average Annual Percent Change (AAPC) was used to describe trends.

The average mortality of children and adolescents aged 5—19 in Shaanxi Province from 2015 to 2022 was 10.86/100000, with a standardized mortality of 11.01/100000, which accounted for 53.86% of the total deaths among children and adolescents. The mortality of males is 2.00 times higher than that of females (χ²=76.77, P<0.001). During the past 8 years, there was no change in injuries mortality among children and adolescents in Shaanxi Province AAPC (95%CI) -4.21% (-11.06%— -2.66%) (P>0.05). The top two causes of death in injuries among children and adolescents are road injuries and drowning, which accounted for 57.87% of the total deaths among children and adolescents. The average annual death rate of road traffic accidents in the general population and men in 2015—2019 was higher than that in 2020-2022 (P<0.05). The average annual death rate from falls in the general population and women was lower in 2015—2019 than in 2020—2022 (P<0.05). The mortality of injuries increased with age groups, with the highest in 15—19 age group (χ²=21.12, P<0.001). The road traffic accident and suicide death rates were the highest in the 15—19 age group (P<0.05).

The main causes of death in injuries among children and adolescents aged 5—19 in Shanxi Province from 2015 to 2022 are road injuries and drowning. The mortality in injuries is higher in male than female. Targeted prevention and control measures should be taken based on the characteristics of mortality in injuries among children and adolescents in Shaanxi Province.

To understand the current situation and influencing factors of the demand for children under three in Chongqing, and to provide a reference for improving the children nursery service system of children under three.

A multi-stage stratified random sampling survey was conducted on the children nursery need of children under three in Chongqing, and the multi-categorical logistic regression was used to comprehensively analyze the influencing factors of children nursery need.

A total of 11 727 families with children under three were surveyed, and the demand for childcare was 53.4%，the age of those who had been enrolled in childcare was mainly at the age of 24-36 months, and the average monthly childcare cost was 2 351.8 yuan, mainly in private childcare institutions. The childcare expectation of families without childcare demand was concentrated in 24-36 months, and the average acceptable monthly childcare cost was 1 607.4 yuan, favoring public childcare institutions. The results of multi-categorical regression analysis showed that parental status (father OR=0.594, 95%CI:0.522-0.676), age (OR=1.012, 95%CI:1.002-1.021), urban and rural (urban OR=1.670, 95%CI:1.490-1.871), education level (university degree or below OR=0.682, 95%CI:0.499-0.931), occupation (government agencies or institutions OR=0.814, 95%CI:0.665-0.996), per capita monthly household income (<4 000 yuan OR=0.857, 95%CI:0.737-0.995), number of families living together (OR=0.915, 95%CI:0.874-0.957), 0-3 years old children (<24 months old OR=0.806, 95%CI:0.714-0.908) were important influencing factors for the childcare needs of children under three.

Chongqing’s childcare needs have not been met, and families should be called upon to optimize the division of responsibilities between parents in childcare. The government should strengthen the training of grandparents in caring skills, improve the ability of family care, increase the supply of inclusive childcare services through multiple channels and reduce the cost of childcare.

To analyze the myopia of middle school students in Heilongjiang Province in 2022, and to provide scientific basis for the development of myopia prevention strategies and measures.

99 114 middle school students in Heilongjiang Province in 2022 were selected to carry out a special survey on health risk behaviors. Their visual acuity and diopter were examined by using a 5-meter standard logarithmic visual acuity chart and desktop optometer. Binary Logistic regression was used to analyze the factors affecting myopia of students.

The total myopia rate of middle school students was 72.44%, including 70.50% junior high school students, 76.91% senior high school students and 64.47% vocational high school students. The myopia rate of students in urban area was higher than that in suburban county. The myopia rate of girls was higher than that of boys. Binary logistic regression analysis showed that: female students (OR=1.38, 95%CI: 1.35-1.43), frequently or always switching seats(OR=1.20, 95%CI: 1.15-1.25), spending more than 2 hours reading and writing after school every day(OR=1.11, 95%CI: 1.07-1.14), spending more than 2 hours a week attending cultural tutoring classes(OR=1.07, 95%CI: 1.03-1.11), parents often or always reminding them to pay attention to their reading and writing posture(OR=1.14, 95%CI: 1.10-1.19), and spending more time using the computer every day(h)≥ 2(OR =1.19, 95%CI: 1.24-1.45), using of mobile electronic devices in the past week(OR=1.11, 95%CI: 1.06-1.16), how often close range eye rest occurs(h)≥ 1(OR=1.11, 95%CI: 1.08-1.15), average daily indoor sitting time(h)≥ 8(OR=1.15, 95%CI: 1.12-1.19) are risk factors for myopia; Suburban counties(OR=0.95, 95%CI: 0.92-0.98), frequently adjusting the height of desks and chairs according to one’s own height(OR=0.94, 95%CI: 0.91-0.97), engaging in outdoor activities during breaks(OR=0.91, 95%CI: 0.89-0.94), having eyes more than 33 cm away from books while reading and writing(OR=0.84, 95%CI: 0.81-0.88), watching TV for≥2(OR=0.84, 95%CI: 0.80-0.88), and having outdoor activity time during the day(h)≥ 2(OR=0.93, 95%CI: 0.90-0.97), average daily sleep time(h)≥ 8(OR =0.80, 95%CI: 0.78-0.83) are protective factors for myopia.

Myopia is related to various factors such as residential area, gender, lifestyle, and behavioral habits.

To explore the status and influencing factors of latent tuberculosis infection among high school students in Chongqing, and to provide technical support for the prevention and control of tuberculosis in schools in Chongqing.

Stratified cluster sampling method was used to select the students of the first and second years of high school in Chongqing in 2023, as the study subjects to detect latent tuberculosis infection with recombinant Mycobacterium tuberculosis fusion protein skin test, to collect the information related to latent tuberculosis infection, and to analyse the influencing factors using Logistic regression model.

A total of 9161 students in the first and second years of high school in Chongqing were included, and 543 latent tuberculosis infections were detected, with a latent tuberculosis infection rate of 5.93%. Multifactorial logistic regression analysis showed that history of previous tuberculosis (OR:4.244, 95%CI:2.239-8.044), history of close contact with tuberculosis (OR:2.096, 95%CI:1.123-3.914), smoking (OR:6.819, 95%CI:3.562-13.053), and staying up late (OR:1.665, 95%CI:1.154-2.402) were risk factors for latent tuberculosis infection in students.

The rate of latent tuberculosis infection among students in the first and second years of high school in Chongqing is low. Not smoking, not staying up late, avoiding close contact with tuberculosis patients, taking good personal protective measures, strengthening physical exercise, and improving immunity can reduce the risk of students being infected with Mycobacterium tuberculosis.

To investigate the current distribution status and multimorbidity patterns of chronic diseases among the elderly population in China, and provide reference for formulating chronic disease management measures.

Based on the CHARLS database in 2020, a total of 10,635 elderly individuals aged 60 and above were included to investigate the prevalence trends of 15 common chronic diseases. The actual expected ratio (O/E) and agglomerative hierarchical clustering analysis were employed to explore the patterns of comorbidity.

The prevalence of chronic diseases among elderly people in China was 86.39%, with hypertension (48.49%), arthritis (43.12%), and stomach diseases (excluding tumors or cancer) (32.06%) being the main causes. The multimorbidity rate was 66.30%, and the top three coexisting diseases were "hypertension+arthritis" (22.28%, O/E=1.07), "hypertension+dyslipidemia" (20.25%, O/E=1.44), and "stomach disease+arthritis" (18.65%, O/E=1.35). The top three coexisting diseases were "hypertension+arthritis+dyslipidemia" (10.31%, O/E=1.70), "hypertension + dyslipidemia + heart disease" (9.70%, O/E=2.65), and "arthritis + stomach disease + hypertension" (9.49%, O/E=1.42). Agglomeration hierarchical cluster analysis was divided into clusters according to malignant tumors, emotional and mental diseases, " stroke + memory related diseases + Parkinson’s disease", "dyslipidemia + diabetes + hypertension + heart disease", "chronic lung disease + asthma + stomach disease + arthritis + liver disease +kidney disease", forming a multimorbidity model.

The overall prevalence of chronic diseases among elderly people in China is increasing year by year, and there is a clustering trend.

To master the information of patients with convulsion epilepsy in phenobarbital in rural epilepsy prevention and management project of Heilongjiang Province, understand the reasons for the withdrawal, analyze the influencing factors, and provide reference for improving the patient retention rate and work quality.

From 2011 to 2020, 3 890 convulsion epilepsy patients received phenobarbital treatment in Heilongjiang Province, of which 807 patients were enrolled. For 807 patients, EpiData, EXCEL and SPSS 19.0 software were used for data entry, processing and statistical analysis of the influencing factors in the withdrawal group, including analysis of variance, univariate analysis, and multivariate survival analysis.

3 890 patients with convulsive epilepsy enrolled in phenobarbital treatment group in rural epilepsy project of Heilongjiang Province, 807 cases dropped out successively, the dropout rate was 20.75%, the primary factors contributing to dropout were relocation, noncompliance with medication, and self-perceived or actual remission. Multivariate Cox regression analysis showed that female patients (HR=1.278, 95%CI:1.112-1.468) were the risk factors for dropping out, and the probability of dropping out in female patients was 1.278 times that of male patients.

The withdrawal rate of phenobarbital epilepsy treatment in rural areas of Heilongjiang Province is relatively high. In the later management work, the publicity and education of epilepsy prevention and treatment knowledge should be strengthened to provide personalized treatment programs and improve the treatment efficiency, especially for female epilepsy patients.

To investigate the current status of fertility intentions among married women of childbearing age in Hebei Province under the background of the three-child policy, and to analyze the influencing factors of fertility support on married women of childbearing age’s fertility intention.

A random cluster sampling method was used to select married women of childbearing age in Hebei Province as the respondents in July 2023, and a self-designed questionnaire was used for the survey. Multinomial logistic regression was used to analyze the influencing factors of fertility intentions among married women of childbearing age.

A total of 1 200 questionnaires were distributed and 1104 valid questionnaires were collected, with a valid recovery rate of 92%. Among the survey subjects, 222 people (20.1%) had no intention of fertility/re-fertility, 263 people (23.8%) intended to have 1 child, 545 people (49.4%) intended to have 2 children, and 74 people (6.7%) intended to have 3 children or more. The results of multinomial logistic regression analysis showed that age, ethnicity, occupation, and residence area were influencing factors of fertility intentions. In terms of fertility support, time support, monthly childcare expenses, maternal care, and economic support were influencing factors of fertility intentions among married women of childbearing age.

The fertility intentions of married women of childbearing age are relatively low, and the intention of having three children is still at a low level. Actively providing fertility support and policies that encourage the fertility intentions of married women of childbearing age, and creating a good fertility environment, will help to enhance the fertility intentions of married women of childbearing age.

To understand the status quo of infectious disease reports automatically exchanged by secondary and above medical institutions in Sichuan province based on regional platform, and provide basis for improving the work on automatic exchange of infectious disease information reports in the next step.

Check and calculate the success rates of exchange and rough exchange through the system, the use of the infectious disease reporting management related systems was investigated by questionnaire survey. T-test and chi-square test were used for comparison between groups, and spearman correlation analysis was used for correlation.

From July to September 2023, the exchange success rate in 68 medical institutions was 92.67%, and the success rate of crude exchange reached 95.87%. Compared with other level medical institutions, municipal medical institutions had higher success rate of exchange and crude exchange, and longer time interval to realize automatic exchange. The exchange success rate was positively correlated with the time interval to realize automatic exchange (r=0.44, P<0.001) and the crude exchange success rate (r=0.51, P<0.001). More than 90% of the institutions had HIS, LIS, PACS. 77.94% of the institutions could automatically generate the report card, more than 80% had the report card management and information statistics query functions. 73.53% realized the automatic early warning of infectious disease report card, and 25% of the institutions reported the card forcibly after the early warning. 88.24% felt that the workload of infectious disease report was reduced after automatic exchange.

The success rate of automatic exchange and the success rate of crude exchange in medical institutions were higher overall, municipal medical institutions were higher than other levels of medical institutions. The construction rate of basic information system in medical institutions was high, but the basic functions of automatic exchange were not perfect. Automatic exchange improves the efficiency of reporting to some extent, but it still could not completely replace manual reporting.

To investigate the influence of social support, self-efficacy and coping style on job burnout of telecommunication employees, and to provide practical guidance for reducing job burnout of telecommunication employees.

This study used stratified random sampling to conduct a questionnaire survey among 8073 telecommunication employees, using Social Support Scale, Coping Style Scale, General Self-Efficacy Scale and Job Burnout Scale. Pearson correlation analysis and SPSS PROCESS model 6 were used to construct a chain mediating effect model to study the mediating path of social support on job burnout of telecommunication employees.

Self-efficacy and coping style had a significant mediating effect on social support and job burnout, and the effect sizes were -0.072 (95%CI: -0.08--0.608) and -0.204 (95%CI: -0.221--0.189), respectively. Self-efficacy and coping style played a significant chain mediating role in the effect of social support on job burnout of telecommunication employees, and the effect size was -0.034 (95%CI: -0.039 - -0.029).

Social support, self-efficacy and coping style are important factors affecting job burnout of telecommunication employees. Self-efficacy and coping style play a chain mediating role between social support and job burnout. The results of this study suggest that increasing social support for telecommunication employees, promoting them to form positive coping styles and improving their self-efficacy are important ways to alleviate their job burnout.

To explore the effects of social support and resilience on bullied secondary school students and non-suicidal self-injury, and analyze the association between social support and resilience, so as to provide reference for preventing school bullying. Method In March 2023, three middle schools in Jiangxi Province were used as site sites to investigate the current situation using self-made general situation questionnaire, Olweus Bully questionnaire, social support scale for adolescents，cognitive emotion regulation questionnaire (CERQ), Ottwa self-injury inventory questionnaire (OSI). To explore the role of social support and resilience in the chain mediation between bullying victimization and non-suicidal self-injury.

The report rate of bullying victimization was 18.56%, and the detection rate of non-suicidal self-injury was 34.4%. Bullying victimization and NSSI were negatively correlated with social support and resilience (r=-0.34 - -0.16, P<0.001), bullying victimization was positively correlated with NSSI (r=0.18, P<0.001), and social support was positively correlated with resilience (r=0.66, P<0.001). The results of mediating effect analysis showed that the simple mediating effect of social support between bullied and non-suicidal self-injury was 0.036 (95%CI:0.014-0.064), and the chain mediating effect of social support and resilience was 0.029 (95%CI: 0.011-0.056).

The bullying experience of secondary school students positively increases the risk of non-suicidal self-injury, and social support and resilience play chain mediating roles in this process. Improve the social support and resilience of secondary school students to reduce the non-suicidal self-injury behavior related to school bullying.

To analyze the mediating effect of depressive symptoms between unhealthy lifestyle and body mass index (BMI), and to provide a reference basis for the prevention of common diseases among adolescents.

In 2023, 88, 594 students were selected by random stratified, class-based cluster sampling method from 12 municipalities in Inner Mongolia (103 counties) for questionnaire survey, to describe the basic demographic characteristics of the students, to explore the correlation between unhealthy lifestyle, depressive symptoms and BMI, and to establish the mediation effect model by using the PROCESS macro program in SPSS 26.0.

The number of detections of unhealthy lifestyle was 85 866, with a detection rate of 96.92 percent; the number of detections of abnormal BMI was 32 078, with a detection rate of 36.21 per cent; and the number of detections of depressive symptoms was 19, 356, with a detection rate of 21.85 per cent. The results showed that the mediating effect value of depressive symptoms on unhealthy lifestyle and body mass index was 0.0770, 95%CI: 0.0513-0.1027, and the mediating effect accounted for 11.35% of the total effect, which indicated that unhealthy lifestyle could mediate the increase of BMI through depressive symptoms.

Adolescents can prevent abnormal body mass index by improving unhealthy lifestyles, and they can also improve the occurrence of depressive symptoms and thus maintain a normal body mass index.

Background Suicide has become a major public health issue of global concern. Suicidal ideation represents the initial psychological and one of the strongest predictorsactivities associated with suicidal behavior. Suicidal ideation is a dynamic state factor rather than a static trait factor, so it is necessary to study the development trajectory of suicidal ideation and its related factors.Objective To investigate the development trajectory and relatedfactors of suicide ideation college students.

From 2019 to 2021,1438 college students in a university in Guangdong Province were selected for three longitudinal tracking each October by using the method of convenient sampling. The Self-rating ideas of suicide scale (SIOSS) was used to measure the level of suicide ideation. Data analysis was mainly based on the Latent Growth Mixed Model(LGMM) to analyze the development trajectory of students’ suicide ideation. Multivariate Logistic Regression model was established to analyze the related factors to the variation of each potential category of suicidal ideation.

From 2019 to 2021, the total scores of college students’ suicidal ideation were 3.79±2.87, 3.71±2.90 and 3.32±2.87, showing a decreasing trend over time. The development tendencies of college students’suicide ideation have been classified into 3 categories: C1 group(worsening suicidal ideation group)(11.8%)，C2 group(persistent low suicidal ideation group)(79.6%), and C3 group (relieving suicidal ideation group) (8.6%). Compared with C1 group, college students who had an average (OR=2.52, 95% CI:1.31-4.86) or happy childhood (OR=3.95,95% CI:2.02-7.74), no history of suicide attempt (OR=9.03，95% CI:3.49-23.36), and were extroverted (OR=1.03, 95% CI:1.01-1.05) were more likely to enter C2 group. Students who were from cities (OR=0.54, 95% CI:0.31-0.93),got high neuroticism scores (OR=0.86, 95% CI:0.84-0.88) were less likely to enter the C2 group. College students with happy childhood life(OR=3.29, 95% CI:1.40-7.74)were more likely to enter the C3 group, but students from cities(OR=0.37, 95% CI:0.18-0.78)were less likely to enter the C3 group.

The development tendencies of college students’ suicide ideation can be classified into three categories: worsening suicidal ideation group,persistent low suicidal ideation group, and relieving suicidal ideation group. The developmental trajectory of suicidal ideation is related to birthplace, childhood life, suicide history, and personality traits.

To investigate the knowledge of monkeypox among men who have sex with men (MSM) in Central Jiangsu Province in 2023, and to provide evidence for the prevention and treatment of monkeypox in this population.

The monkeypox questionnaire designed by Jiangsu Provincial Center for Disease Control and Prevention was used to investigate HIV Voluntary Counseling & Testing (VCT) clinic and social organizations in central Jiangsu Province. Excel 2010 and SPSS19.0 software were used to organize and analyze the data. Also, univariate and multivariate Logistic regressions were used to analyze the factors affecting the awareness rate of monkeypox knowledge. χ² test was used to compare the difference of concern degree of monkeypox among people with different characteristics.

A total of 1 290 valid questionnaires were collected. The majority were aged from 26 to 50 years, accounting for 65.04% (839/1 290). The majority of the students were college students, bachelor students or above, accounting for 64.26% (829/1 290). The awareness rate of monkeypox was 26.12%, and the complete awareness rate was 15.27%. The results of multivariate Logistic regression analysis showed that the related factors with higher awareness rate of monkeypox included Taizhou (OR=6.710, 95%CI: 4.309-10.447), high school/technical school (OR=2.461, 95%CI: 1.270-4.769), college (OR=2.515, 95%CI: 1.311-4.825), bachelor’s degree or above (OR=2.253, 95%CI: 1.184-4.288), concerned about monkeypox epidemic and related situation (OR=1.684, 95%CI: 1.188-2.387) (all P < 0.05). The correct rates of monkeypox symptoms, preventive measures and transmission routes were 30.78%, 42.25% and 27.75%, respectively. 1 186 people (91.94%) paid attention to monkeypox epidemic and prevention knowledge from WeChat, Weibo and other network new media. MSM with different regions (χ²=65.348, P<0.001), age groups (χ²=19.422, P=0.001), educational levels (χ²=31.447, P<0.001), marital status (χ²=11.162, P=0.025), results of the latest HIV test (χ²=37.793, P<0.001), sexual orientations (χ²=39.441, P<0.001), whether they had sexual contact with the same sex in the last 6 months (χ²=29.329, P<0.001), and whether they had sexual contact with overseas personnel (χ²=29.199, P<0.001), paid different attention to monkeypox information, and the differences were statistically significant.

The awareness rate of MSM monkeypox knowledge in central Jiangsu Province is low, and the accuracy rate of monkeypox symptoms, transmission routes and prevention and control measures are low. Therefore, it is necessary to publicize monkeypox symptoms and transmission routes through new media such as WeChat, Weibo, Douyin and Baidu in the later stage.

To analyze the association of 11 anthropometric indicators (AIs) with gastric cancer and precancerous lesions in people aged 40-69 years in Yangzhong City.

Using the cluster sampling method, 10 698 residents aged 40-69 years who participated in upper gastrointestinal cancer screening in Yangzhong City from November 2017 to December 2022 were selected for questionnaire survey, physical examination, endoscopy and pathological diagnosis. Multivariate logistic regression was used to analyze the association between AIs [body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), body fat percentage (BF%), conicity index (CI), body adiposity estimator (BAE), a body shape index (ABSI), body adiposity index (BAI), body roundness index (BRI) and abdominal volumetric index (AVI)] and gastric cancer and precancerous lesions.

The prevalence of gastric cancer and precancerous lesions was 39.37% among 10 115 residents. The results of multivariate logistic regression showed that compared with those in quartile 1 (Q1), the Q3 and Q4 populations of BMI had an 11.1% (OR=0.889, 0.791-0.999) and 12.4% (OR=0.876, 0.779-0.984) lower risk of gastric cancer and precancerous lesions, respectively. The Q2, Q3 and Q4 populations of BF% had 14.2% (OR=0.858, 0.756-0.974), 17.4% (OR=0.826, 0.689-0.991) and 26.6% (OR=0.734, 0.603-0.893) lower risk of gastric cancer and precancerous lesions risk, respectively. The Q2 and Q4 populations of the BAE had reduced the risk of gastric cancer and precancerous lesions by 13.2% (OR=0.868, 0.766-0.983) and 21.3% (OR=0.787, 0.648-0.957). The risk of gastric cancer and precancerous lesions in BAI’s Q2 and Q3 populations was reduced by 13.7% (OR=0.863, 0.767-0.970) and 13.1% (OR=0.869, 0.769-0.983), respectively. Stratified analysis showed that BMI, BF%, BAE and BAI were associated with a reduced risk of non-cardia gastric cancer and precancerous lesions (all P<0.05). However, only the Q2 level of BAE was associated with a reduced risk of cardia gastric cancer and precancerous lesions compared to the Q1 (P<0.05).

Increased levels of BMI, BF%, BAE, and BAI among residents aged 40-69 years in Yangzhong City are associated with a reduced risk of gastric cancer and precancerous lesions. However, most of this association apply to non-cardia but not cardia.

To explore potential classifications and characteristics of mental health literacy among HIV-positive men who have sex with men.

From November 2023 to January 2024, 226 HIV-positive MSM in a tertiary hospital in Nanjing were selected by the convenience sampling method and were investigated by general information questionnaire and multicomponent mental health literacy scale. Latent class analysis and multivariate logistic regression analysis were used to explore the categorical characteristics and influencing factors of mental health literacy in this group.

The mental health literacy characteristics of HIV-positive MSM could be classified into low literacy group (22.1%), resource deficient group (38.1%), and high literacy group (39.8%). Multiple logistic regression analysis showed that patients aged 18-34 (OR=5.573, 95%CI=1.020-30.449) were more likely to be in the resource deficient group than the low literacy group, and those who had participated in learning mental health skills (OR=0.126, 95%CI=0.033-0.476) were more likely to be in the high literacy group. Compared with the high literacy group, patients with literacy level of junior high school or below (OR=15.992, 95%CI=2.036-125.591), high school or junior college (OR=2.805, 95%CI=1.098-7.166), length of time to diagnosis of HIV infection <1 year (OR=8.440, 95%CI=1.628-43.742), and with comorbidities (OR=6.619, 95%CI=1.077-40.663) were more likely to be in the low literacy group; and patients with a monthly per capita family income of <3000 yuan (OR=6.241, 95%CI=1.088-35.814) were more likely to be in the resource deprived group.

There are three potential categories of mental health literacy among HIV-positive MSM. In the future, targeted intervention strategies should be developed to improve the level of their mental health literacy and further improve their mental health according to this group’s different category characteristics and influencing factors.

To understand the willingness to use pre-exposure prophylaxis (PrEP) among MSM in Guiyang, explore related factors, so as to provide reference for promoting PrEP in Guiyang and Guizhou Province.

Two social organizations in Guiyang were recruited among MSM from gay bars, WeChat groups and other social venues and the Internet by convenient sampling method from April to June, 2022. Questionnaires were collected using the “Wen Juan Xing” platform, the contents of the survey included demographic information, behavioral characteristics, knowledge of PrEP, the willingness to use PrEP and so on. Univariate analysis of the willingness to use PrEP was used Chi-square test, logistics regression was carried out to analyze the multiple-factors related to the willingness to use PrEP. Taking the willingness to use PrEP as the dependent variable, univariate and multivariate logistics regression was carried out to analyze the factors related to the willingness to use PrEP.

608 valid questionnaires were collected. A total of 146 people (24.0%) knew about PrEP, 216 people (35.5%) had used PrEP before, and 525 people (86.3%) were willing to use PrEP if they had high-risk behaviors. The results of multivariate analysis showed that non-Guiyang resident (OR=3.09, 95%CI:1.42-6.73), living in Guiyang for 7-12 months (OR=5.12, 95%CI:2.25-11.65) and more than 1 year (OR=4.19, 95%CI:1.85-9.49), employed (OR=17.05, 95%CI:4.14-70.26), unemployed (OR=6.29, 95%CI:1.18-33.59), tested for HIV in the last 1 year (OR=3.77, 95%CI:1.70-8.38), those who had previously used PrEP (OR=15.85, 95%CI: 5.12-49.11) and aware of PrEP (OR=4.82, 95%CI: 1.88-12.38) were more likely to use PrEP.

The MSM population surveyed in Guiyang has a low awareness rate of PrEP, higher willingness to use PrEP, and relative factors, develop targeted measures to promote knowledge about PrEP according to relative factors, so as to improve the knowledge of PrEP, confidence and willingness to use PrEP. Promote the use of PrEP in the context of comprehensive AIDS prevention and control, such as the use of condoms, to reduce the risk of HIV infection.

To explore the non-immunization vaccines hesitancy and associated factors among parents of 0-18 years old children in Karamay.

Based on the theory of planned behavior (TPB), we used a stratified sampling method to select parents of 0-18 years old children in 12 schools of Karamay for a questionnaire-based survey．The structural equation model was used to determine relationships between variables.

Of 1 258 parents included in the analysis, the incidence of vaccine hesitancy among those was 38.95%. Logistic regression analysis showed that parents with younger children, higher educated, higher income, and longer local residence were less likely to be hesitant. The indicators of model fit are in line with the theoretical requirements. The model explains 56% of the variance of parental hesitancy to vaccinate. Attitudes (β_standard=-0.36, P<0.01), subjective norms (β_standard=-0.23, P<0.01), perceived behavioral control (β_standard=-0.21, P<0.01), and perceived risk (β_standard=-0.12, P<0.01) were associated with non-immunization vaccines hesitancy.

The TPB model can better explain parents’ hesitancy to receive non-immunization vaccines. To increase parental willingness about vaccinate, it is essential to strengthen parents’ trust in vaccine quality and knowledge of vaccines. Furthermore, utilizing physicians and social media for health education is crucial.

To explore the relationship between H-type hypertension and chronic kidney disease (CKD) and provide scientific basis for the prevention and treatment of chronic kidney disease.

From December 2021 to December 2022, 257 patients with CKD were randomly collected from the Department of Nephrology of Hunan Provincial People’s Hospital, and 257 patients were collected in the physical examination department as the control group. Data on general demographic characteristics, lifestyle habits, disease history, and clinical indicators were collected for all study subjects. The epidemic status and influencing factors of CKD, and the relationship between H-type hypertension and CKD were analyzed by univariate and multivariate analysis methods. An interaction model was constructed to analyze the interaction effect of homocysteine (Hcy) and hypertension on the onset of CKD. The effect of H-type hypertension and related influencing factors on CKD were explored by subgroup analysis.

The results of univariate analysis of general demographic characteristics and clinical indicators between CKD and control groups showed: age, ethnicity, educational level, per capita income, exercise status, sleep duration, BMI, history of H-type hypertension, triglycerides (TG), High-density lipoprotein cholesterol (HDL), albumin (ALB), glomerular filtration rate (GFR), blood urea nitrogen (BUN), uric acid (UA), Hcy, total bilirubin (TBIL), direct bilirubin (DBIL), C reactive protein (CRP) levels (P<0.05). Dichotomized Logistic regression analysis showed that the risk of CKD, adjusted for age, nationality, educational level, family income, exercise, sleep duration, BMI, TG, HDL, ALB, GFR, BUN, UA, TBIL, CRP was 2.333 times higher than in those without H-type hypertension(OR=2.333, 95%CI: 1.365-3.989, P=0.002). The interaction results between hyperhomocysteinemia (HHcy) and hypertension suggested that there was a positive additive interaction between HHcy and hypertension, with no multiplicative interaction. There was an interaction between H-type hypertension and age, educational level, average annual family income, and sleep duration on the onset of CKD (P<0.05).

H-type hypertension is a risk factor for CKD, and there is an additive interaction between the effects of HHcy and hypertension on CKD.

To construct a symptom network for patients with hypertensive cerebral hemorrhage in the acute phase, and to explore the core symptom clusters to provide reference for healthcare professionals to carry out individualized and precise symptom management.

From December 2022 to January 2024, 423 hypertensive cerebral hemorrhage patients hospitalized in the neurosurgery departments of three tertiary-level A hospitals in Hebei Province were conveniently selected for the study. General information questionnaire, Chinese version of Memory Symptom Assessment Scale, National Institutes of Health Stroke Scale, and Stroke Specific Quality of Life Scale were used to collect data. Symptom clusters were analyzed by exploratory factor analysis, symptom networks were constructed in R language to analyze the centrality indexes, and the symptom clusters that had the greatest impact on patients’ quality of life were clarified through stratified regression to determine the core symptom clusters.

The most common symptoms in patients with hypertensive cerebral hemorrhage were pain (83.5 %), worry (80.6%), nausea (75.7%), and the most severe symptom was pain (2.29±0.05), followed by nausea (1.93±0.06) and worry (1.72±0.06). Exploratory factor analysis identified five symptom clusters, namely, sickness symptom cluster, dysfunction symptom cluster, mental-emotional symptom cluster, respiratory symptom cluster, and gastrointestinal symptom cluster, with a cumulative variance contribution of 61.832%. The symptom with the highest expected impact value in the symptom network was pain (r_s=1.17). Stratified regression analyses showed that the cluster of sickness symptoms had the greatest impact on quality of life (β=-4.677，95%CI：-5.224 - -4.131，P<0.001), explaining 46.5% of the model.

The symptom cluster is the core symptom cluster in the acute phase of hypertensive cerebral hemorrhage patients, based on which healthcare professionals can take appropriate interventions to carry out symptom management and further improve the efficiency of symptom management.

To show that the current situation and influencing factors of loneliness in the elderly under different chronic diseases, and propose targeted solutions.

This survey adopted the convenience sampling method, selecting elderly people from five communities in Harbin for physical examinations and distributing questionnaires to conduct statistical analysis of the survey data.

The loneliness scores of the elderly without chronic diseases, single chronic diseases and multiple chronic diseases were (42.83±9.08), (44.46±9.14) and (46.21±8.66), respectively. Age, education level, marital status, per capita monthly income of households, residence status, social support, and death anxiety were the common factors affecting loneliness in the three types of elderly (P<0.05). In terms of elderly people with multiple chronic diseases, those who worked as civil servants (95%CI:-11.515--3.602), employees of enterprises/institutions (95%CI: -6.117--2.443), and farmers(95%CI: -7.485--0.909) before retirement had lower levels of loneliness(P<0.05).

Elderly people with chronic diseases have a higher sense of loneliness and need to pay more attention to their mental health. It is necessary to reduce the level of loneliness by improving the level of social support, reducing death anxiety, improving social welfare and medical policies, reducing the financial burden, and improving family relations.