To analyze the association of 11 anthropometric indicators (AIs) with gastric cancer and precancerous lesions in people aged 40-69 years in Yangzhong City.
Using the cluster sampling method, 10 698 residents aged 40-69 years who participated in upper gastrointestinal cancer screening in Yangzhong City from November 2017 to December 2022 were selected for questionnaire survey, physical examination, endoscopy and pathological diagnosis. Multivariate logistic regression was used to analyze the association between AIs [body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), body fat percentage (BF%), conicity index (CI), body adiposity estimator (BAE), a body shape index (ABSI), body adiposity index (BAI), body roundness index (BRI) and abdominal volumetric index (AVI)] and gastric cancer and precancerous lesions.
The prevalence of gastric cancer and precancerous lesions was 39.37% among 10 115 residents. The results of multivariate logistic regression showed that compared with those in quartile 1 (Q1), the Q3 and Q4 populations of BMI had an 11.1% (OR=0.889, 0.791-0.999) and 12.4% (OR=0.876, 0.779-0.984) lower risk of gastric cancer and precancerous lesions, respectively. The Q2, Q3 and Q4 populations of BF% had 14.2% (OR=0.858, 0.756-0.974), 17.4% (OR=0.826, 0.689-0.991) and 26.6% (OR=0.734, 0.603-0.893) lower risk of gastric cancer and precancerous lesions risk, respectively. The Q2 and Q4 populations of the BAE had reduced the risk of gastric cancer and precancerous lesions by 13.2% (OR=0.868, 0.766-0.983) and 21.3% (OR=0.787, 0.648-0.957). The risk of gastric cancer and precancerous lesions in BAI’s Q2 and Q3 populations was reduced by 13.7% (OR=0.863, 0.767-0.970) and 13.1% (OR=0.869, 0.769-0.983), respectively. Stratified analysis showed that BMI, BF%, BAE and BAI were associated with a reduced risk of non-cardia gastric cancer and precancerous lesions (all P<0.05). However, only the Q2 level of BAE was associated with a reduced risk of cardia gastric cancer and precancerous lesions compared to the Q1 (P<0.05).
Increased levels of BMI, BF%, BAE, and BAI among residents aged 40-69 years in Yangzhong City are associated with a reduced risk of gastric cancer and precancerous lesions. However, most of this association apply to non-cardia but not cardia.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |