To study the relationship between the cardiometabolic index (CMI) and hyperuricemia (HUA) in Guizhou minorities.
Based on the "China Multi-ethnic Cohort Study", 16 630 Miao, Dong and Bouyei population aged 30 to 79 years were included in the study. Logistic regression model was used to analyze the association between CMI and HUA, restricted cubic spline was used to analyze the dose-response relationship between CMI and HUA, and ROC curve was used to analyze the predictive value of CMI for HUA.
The overall detection rate of HUA was 22.8%, and those of Miao, Dong and Bouyei nationalities were 24.4%, 25.2% and 18.5%, respectively. In the total population, Miao, Dong and Bouyei populations, after adjusting for covariates, compared with Q1, the ORs for HUA were 4.39 (95%CI: 3.76-5.12), 3.96 (95%CI: 3.03-5.18), 4.28 (95%CI: 3.36-5.46), and 5.55 (95%CI: 4.08-7.54) in CMI Q4 group, respectively. There was a non-linear dose-response relationship between CMI and risk of HUA (P for nonlinear < 0.001). ROC curve analysis showed that, the area under the curve (the best cut-off value, sensitivity and specificity) of CMI for predicting the risk of HUA in the total population, Miao, Dong and Bouyei populations were 0.742 (0.641, 68.3%,68.8%), 0.724 (0.651, 63.8%, 70.8%) 0.741 (0.654, 68.5%, 68.1%), 0.775 (0.555, 68.8%, 73.0%).
CMI is associated with the increased risk of HUA in different ethnic populations, and can be used as an indicator for predicting HUA in ethnic minority populations in Guizhou province.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |