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To master the information of patients with convulsion epilepsy in phenobarbital in rural epilepsy prevention and management project of Heilongjiang Province, understand the reasons for the withdrawal, analyze the influencing factors, and provide reference for improving the patient retention rate and work quality.
From 2011 to 2020, 3 890 convulsion epilepsy patients received phenobarbital treatment in Heilongjiang Province, of which 807 patients were enrolled. For 807 patients, EpiData, EXCEL and SPSS 19.0 software were used for data entry, processing and statistical analysis of the influencing factors in the withdrawal group, including analysis of variance, univariate analysis, and multivariate survival analysis.
3 890 patients with convulsive epilepsy enrolled in phenobarbital treatment group in rural epilepsy project of Heilongjiang Province, 807 cases dropped out successively, the dropout rate was 20.75%, the primary factors contributing to dropout were relocation, noncompliance with medication, and self-perceived or actual remission. Multivariate Cox regression analysis showed that female patients (HR=1.278, 95%CI:1.112-1.468) were the risk factors for dropping out, and the probability of dropping out in female patients was 1.278 times that of male patients.
The withdrawal rate of phenobarbital epilepsy treatment in rural areas of Heilongjiang Province is relatively high. In the later management work, the publicity and education of epilepsy prevention and treatment knowledge should be strengthened to provide personalized treatment programs and improve the treatment efficiency, especially for female epilepsy patients.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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