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Bidirectional association of metabolic syndrome and its components with depression in middle-aged and elderly Chinese people
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Yu-tong LI, Jian-qian CHAO, Wei ZHOU
Modern Preventive Medicine | 2024, 51(16) : 2881 - 2886
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Modern Preventive Medicine | 2024, 51(16): 2881-2886
• Epidemiology and Statistical Methods Advances •
Bidirectional association of metabolic syndrome and its components with depression in middle-aged and elderly Chinese people
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Yu-tong LI, Jian-qian CHAO, Wei ZHOU
Affiliations
  • School of Public Health, Southeast University, Nanjing, Jiangsu 210009, China
Published: 2024-08-25 doi: 10.20043/j.cnki.MPM.202401091
Outline
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Objective

To explore the bidirectional association between metabolic syndrome(MS) and depression in middle-aged and elderly adults in China.

Methods

This study used participants aged 45 and above from publicly available longitudinal data from the China Health and Retirement Longitudinal Study(CHARLS) from 2011 to 2018. The baseline was based on 2011 data. Stage I studied the longitudinal association of baseline MS with follow-up depression, while Stage II studied the association of baseline depression with follow-up MS. Stage III further investigated the bidirectional association between MS and depression using a cross-lagged panel model, and the follow-up data for all three stages used 2015 data including blood routine examination and physical examinations.

Results

There was a bidirectional association between the two diseases. The baseline MS and its components showed a positive correlation with the follow-up depression(β=0.052, P<0.01), and vice versa(β=0.305, P<0.01), but there were differences in gender subgroups.

Conclusion

There is a bidirectional correlation between MS and its components and depression in the middle-aged and elderly population in China. We should identify, monitor, and intervene in early MS and depression.

Metabolic syndrome(MS)  /  Depression  /  Bidirectional association  /  CHARLS
Yu-tong LI, Jian-qian CHAO, Wei ZHOU. Bidirectional association of metabolic syndrome and its components with depression in middle-aged and elderly Chinese people[J]. Modern Preventive Medicine, 2024 , 51 (16) : 2881 -2886 . DOI: 10.20043/j.cnki.MPM.202401091
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Year 2024 volume 51 Issue 16
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Article Info
doi: 10.20043/j.cnki.MPM.202401091
  • Receive Date：2024-01-06
  • Online Date：2026-03-18
  • Published：2024-08-25
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  • Received：2024-01-06
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Affiliations
    School of Public Health, Southeast University, Nanjing, Jiangsu 210009, China
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红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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