The primary objective of this study was to investigate the potential correlation between the presence of 22 metals in urine and the risk of developing gallstones in Bouyei population in qiannan region, ultimately aiming to furnish a scientific foundation for early preventative measures and targeted interventions.

From July 2018 to August 2019, a baseline survey was conducted among residents aged 30 to 79 years in Qiannan Bouyei and Miao Autonomous Prefecture using multistage stratified cluster sampling, including questionnaires, physical examination and ICP-MS to detect urine metal concentration. Urinary metal concentrations were divided into four groups (Q1, Q2, Q3, Q4), and binary logistic regression model was used to analyze the relationship between single metal and gallstone risk. At the same time, the dose-response relationship between metal concentration and gallstone risk was investigated by using restricted cubic splines.

The gallstone detection rate of Bouyei population was 8.825%. After adjusting for covariates, binary logistic regression analysis revealed that in the male group, compared to the Q1 group, there was a positive association between gallstone risk and selenium in the Q2 group (OR=1.894, 95%CI: 1.046-3.431), Se in the Q3 group (OR=1.912, 95%CI: 1.053-3.472), and Fe in the Q3 group (OR=1.827, 95%CI: 1.040-3.210). In the female group, Al in the Q3 group (OR=1.460, 95%CI: 1.050-2.028) was positively associated with gallstone risk, while Na in the Q4 group (OR=0.654, 95%CI: 0.452-0.948) was negatively associated with gallstone risk, with a dose-response relationship observed.

There is a significant correlation between the concentration of certain metals in urine and the risk of gallstones. In the Bouyei female population in particular, urinary aluminum and urinary sodium concentrations have a significant impact on gallstone formation, providing possible directions for future prevention and treatment strategies.

To explore the association between the accumulation of cardiovascular risk factors and the elevated resting heart rate in community residents aged 35-75 years in Shanghai

Participates were obtained from the China PEACE Million Persons Projects. 8 districts in Shanghai were selected from 2017 to 2019, and the screening was carried out between adults aged 35 to 75 years in communities. Questionnaires, physical examinations and laboratory tests were conducted. The Kruskal-Wallis test and Cochran-Mantel-Haenszel test were used to compare groups by using R 4.2.2 software. Multivariate logistic regression was performed to explore the correlation between the number of common risk factors for cardiovascular diseases, the combination of different risk factors and elevated resting heart rate.

Among 87934 participants, the mean age was 59.1±9.7 years. Compared with the group with no risk factors, the OR(95%CI) for elevated resting heart rate for the groups with 1, 2, 3 and ≥4 risk factor were 1.42（1.36-1.47）、1.70（1.53-1.77）、1.94（1.84-2.05）and 2.17（1.99-2.36）, respectively. The risk of elevated RHR was the most strongly influenced by the cardiovascular risk factor clustering number in the female group aged 35 to 44 with ≥4 risk factors,and the OR(95%CI) was 3.77 (2.10-4.27). In the combination of risk factors, more metabolic risk factors were associated with a higher risk of elevated resting heart rate.

Resting heart rate may serve as a simple and practical indicator of the cumulative effect of multiple cardiovascular risk factors, which can help early identification of individuals at high cardiovascular risk in relatively healthy people, so as to enable early intervention.

The epidemic situation of influenza from 2014 to 2023 in Huanggang City was analyzed to provide reference for prevention and control of influenza in Huanggang City.

The data of influenza online report, ILI monitoring data and etiological detection data in Huanggang City from 2014 to 2023 were collected and analyzed.

From 2014 to 2023, the annual incidence of influenza in Huanggang City ranged from 5.38/100,000 (2014) to 1,178.19/100,000 (2023), with a trend of first increasing (2014-2019), then decreasing (2020-2022), and reaching a peak in 2023.Retrospective spatiotemporal scanning analysis showed that the onset time was mainly concentrated in December of each year and January and February of the following year. In the epidemic season, Huangzhou, Luotian and Qichun were the main cluster areas of Class I and Class II. The ILI% value of each year in Huanggang City from 2014 to 2023 ranged from 4.41% to 13.17%, and the difference of ILI% each year was statistically significant (χ²=83 652.46,P<0.01), and the annual change trend was similar to that reported by influenza network.The positive rate of influenza virus in ILI case samples showed the characteristics of peak in winter and spring and small peak in summer, and H3N2, H1N1 and BBV were alternately or co-prevalent in each year and within each year.The analysis of correlation results between ILI% and positive rate of influenza virus showed that: except 2014-2016 and 2020-2022, the other 4 years showed positive correlation, and the P-value was less than 0.05,

The prevalence of influenza in Huanggang showed an increasing trend year by year, with obvious seasonal characteristics and temporal and spatial aggregation. The dominant strains, mainly H1N1, H3N2 and BV, alternated or co-circulated within the year and between different years.

To analyze the epidemiological characteristics of hepatitis C in Dongguan City from 2005 to 2022, and to provide scientific theoretical guidance for the prevention and treatment of hepatitis C in the future.

The reported cases and demographic data in Dongguan City from 2005 to 2022 were collected and analyzed by Excel 2016, SPSS25.0 and Joinpoint Regression Program 4.9.1.0 software. The value is 0.05 as a standard test.

From 2005 to 2022 the average annual incidence of hepatitis C in Dongguan city was 12.84/100 000. The annual incidence showed an upward trend from 2005 to 2011 (APC=15.74%) and a downward trend from 2011 to 2021 (APC=-5.41%). The incidence of reported cases in Guancheng district (34.78/100 000), Shilong Town (25.33/100 000) and Xiegang Town (17.90/100 000) were among the top three in all the towns and streets. The average annual incidence in males (17.45/100 000) was higher than that in females (8.17/100 000), moreover, the incidence in male has declined since 2014 (APC=-7.01%), and the incidence in female has declined since 2011 (APC=-7.64%). The ages of onset were mainly from 20 to 49 years old(15 873 cases, 75.07%),In the age group of 50 to 59 years, the annual incidence showed an upward trend(AAPC=24.47%). The most affected population group was housewives and unemployed individuals (6 003 cases,28.39%) and the annual constituent ratios was on the rise (AAPC=6.59%).

The reported incidence level of hepatitis C in Dongguan is higher than that in China. And the annual reported incidence has declined since 2011. Improving the prevention and cure of hepatitis C among men, 20 to 59 age group and housewives and unemployed individuals is suggested to reduce the incidence of hepatitis C effectively.

To analyze the epidemic characteristics of breakthrough cases of varicella in Shapingba District, Chongqing, and provide reference for the prevention and control of the varicella epidemic in the area.

Collect information on varicella cases and their vaccination in Shapingba District from 2019 to 2023, Use descriptive epidemiological methods to analyze the epidemiological characteristics of varicella breakthrough cases, and use linear regression to analyze the relationship between breakthrough cases and age at the time of vaccination and the time interval between vaccination and onset of disease.

From 2019 to 2023, there were a total of 802 breakthrough cases of varicella in Shapingba District, Chongqing, accounting for 14.87% of the total number of varicella cases. The majority of cases were vaccinated with one dose of varicella (648 cases, accounting for 80.80%), and the differences in composition among different years were statistically significant (χ²=16.400,P<0.005); The epidemic has a bimodal distribution, from October to December and May to July each year. The least cases are in winter (142 cases, accounting for 11.68%), and the most cases are in spring (198 cases, accounting for 17.32%). The composition differences between different seasons are statistically significant (χ²=16.348, P<0.001); The breakthrough cases of chickenpox are mainly male, with the highest incidence among primary school students aged 6～10, and the differences in composition are statistically significant (χ²=877.420, P<0.001); The time interval from the first dose of chickenpox vaccine to the onset of breakthrough cases was 46 days to 17 years, with a median \[M(P₂₅,P₇₅)\] of 7 years (4 years, 10 years). The median time interval between scattered children, primary school students, and middle school students was 3 years (2 years,4 years), 8 years (6 years, 9 years), and 12 years (11 years,14 years), respectively, with statistical significance (H=497.280, P<0.001); There is a negative correlation between age at the time of first dose vaccination and the interval between onset of the disease in breakthrough cases, with a correlation coefficient of r=-0.230 (t=-6.693, P<0.001).

Breakthrough cases of varicella in Shapingba, Chongqing are mainly concentrated in primary school students during the start of the school season, with an interval of 7 years between onset. It is necessary to further strengthen the prevention and control of the varicella epidemic in primary schools, further improve the vaccination rate of children with varicella vaccines, and recommend receiving two doses of vaccines before starting primary school to reduce the risk of breakthrough cases.

To understand the epidemiological characteristics of non-occupational carbon monoxide poisoning incidents in Beijing from 2018 to 2022, and to explore targeted prevention and control measures.

The data were from the National Public Health Emergency Reporting Management Information System. Descriptive epidemiological methods were used to analyze non-occupational carbon monoxide poisoning incidents in Beijing from 2018 to 2022. Relative risk (RR) was used to assess the risk of morbidity and mortality.

From 2018 to 2022, a total of 1841 non-occupational carbon monoxide poisoning incidents were reported in Beijing, with 2729 cases of poisoning and 31 deaths. The annual morbidity and mortality were 25.14 and 0.29 cases per million, respectively. There were two peaks of poisoning cases in spring and winter, accounting for 49.98% and 24.00% of the total cases, respectively. The highest incidence occurred between 8 and 11 o ’clock, accounting for 22.83%. In the inner suburbs, outer suburbs and urban areas, the incidence of non-occupational carbon monoxide was 0.96 cases/100 000, 1.27 cases/100 000 and 18.79 cases/100 000, and the mortality was 0.02 cases/100 000, 0.02 cases/100 000 and 0.11 cases/100 000, respectively. The poisoning incidents mainly occurred in residential families in 1633 cases, accounting for 88.70%; This was followed by 118 restaurants, accounting for 6.41 percent. The proportion of household poisoning incidents decreased from 92.10% in 2018 to 84.13% in 2022. The proportion of poisoning incidents in restaurants increased year by year from 4.23% in 2018 to 10.05% in 2022. The proportion of poisoning cases occurring at home decreased from 86.39% in 2018 to 71.84% in 2022. The proportion of poisoning cases in restaurants increased from 9.88% in 2018 to 20.57% in 2022.

The incidence and death risk of non-occupational carbon monoxide poisoning in Beijing is not balanced among regions, and the proportion of poisoning incidents in restaurants is increasing year by year. Targeted measures should be taken to strengthen the prevention and control work in the outer suburbs and key restaurants.

To construct a land use regression (LUR) model for particulate matter with an aerodynamic diameter ≤2.5 μm (PM2.5) in Zunyi.

Collect and organize hourly PM2.5 monitoring data from routine air quality monitoring stations from January 1, 2020 to December 31, 2020, as well as geographic information data such as land use, roads, population density, altitude, and meteorological factors in Zunyi. Conduct multiple stepwise linear regression with PM2.5 concentration as the dependent variable and geographic information variables and meteorological factors as independent variables to construct a model. Use leave-one-out cross validation (LOOCV) to verify the performance of the model.

The model formula is Y=72.656-0.026×altitude-0.009×NDVI-0.62×average temperature-383.512×average precipitation. The model had R²=0.74, adjusted R²=0.72, cross validation R²=0.69, RMSE=3.51, and a high spatial resolution (250 m×250 m).

The model fits well and fully reflects the influencing factors of PM2.5 spatial distribution in Zunyi. It can be used to estimate individual exposure levels and provide strong support for environmental health epidemiological research.

To assess the presence of enteroviruses and diarrheal viruses in the environmental sewage of Aba in 2022, and to provide evidence supporting effective control measures against these viruses.

Sewage samples were collected monthly throughout 2022, then eluted and concentrated by anionic membrane adsorption.Through this, enteroviruses were isolated and identified. At the same time, nucleic acid was extracted from the concentrated liquid, and real-time fluorescent PCR was used to detect several diarrhea viruses, such as group A rotavirus, norovirus, Sapovirus, human astrovirus and enteric adenovirus.

A total of 12 environmental sewage samples were collected from January to December 2022. Out of these, 3 strains of polioviruses and 9 non-polio enteroviruses were isolated. All 3 poliovirus strains were detected as Type 3 vaccine-like poliovirus (PV) strains. Group A rotavirus and norovirus genotype II were detected every month. Norovirus type I and enteric adenovirus were observed in all months except November. Human astrovirus was absent in samples from July, August, November and December. Sapovirus was not identified throughout the year.

Enteroviruses and diarrheal viruses exist widely in Aba’s environmental sewage. Environmental sewage surveillance can offer a comprehensive view of these viruses’ etiological and epidemiological characteristics. Continuous environmental sewage surveillance can predict and warn the epidemic and outbreak of enteroviruses and diarrheal virus-related diseases.

To describe and analyze the burden and changing trends of ischemic heart disease(IHD)attributed to dietary risks in China from 1990 to 2021, and to provide a scientific basis for the prevention and control of IHD in China.

Standardized DALY rates and standardized mortality rates for IHD in China from 1990 to 2021 were extracted from the Global Burden of Disease database(GBD 2021).

In 2021, the standardized DALYs rate and mortality rate of IHD attributed to dietary risks in China were 820.87 and 44.26 per 100,000 respectively, showing a decrease of 14.45% and 5.24% compared to 1990. China’s rates were only higher than regions with high sociodemographic index and lower than global and other regional levels.Dietary risks were significantly higher in males compared to females, with the main risk factors being high-sodium diet, lowwholegrain diet, and high omega-6 polyunsaturated fatty acid diet.Both DALYs rate and mortality rate increased significantly with age.The overall trend from 1990 to 2021 shows a decline in the standardized DALYs rate and mortality rate of IHD attributed to dietary factors in China, with an Average Annual Percentage Change(AAPC) of 0.54% and 0.24% respectively.

The burden of disease and mortality rate of IHD attributable to dietary risks in China have shown an overall declining trend. However, the disease burden attributable to dietary risks is higher in males than in females, and higher in those aged 70 and above compared to those under 70. The burden of IHD attributable to dietary risks is expected to continue rising. To alleviate the burden of IHD, it is essential to enhance health education for males and middle-aged and elderly populations, increasing their awareness of IHD prevention and control. This can be achieved by promoting healthy eating habits and lifestyle practices to improve physical fitness management.

To understand the intake of added sugars among primary school students, to analyze the sources and influencing factors of intake, and to propose improvement measures.

A stratified cluster sampling method was used to select 12,603 primary school students in Lianyungang as the research subjects. A food atlas-based questionnaire was used to investigate the intake of foods with added sugars and calculate daily intake of added sugars.

The median added sugar intake of primary school students was 22.1 g/day, 45.7% of students consumed more than 25 g/day, and 21.7% of students consumed more than 50 g/day. Sugar-sweetened beverages, flavored yogurt, pastries and sweets were the four main sources of added sugar intake among primary school students (accounting for 38.3%, 24.0%, 14.1% and 12.1% respectively). Multiple linear regression analysis showed that boys, higher grade, higher BMI, and less sleep were associated with increased intake of added sugars.

The excessive intake of added sugar by primary school students in Lianyungang was quite prominent. On the one hand, nutrition education should be carried out to publicize the harm of excessive intake of added sugar.On the other hand, it isrecommended to include the added sugar content in the nutrition label to guide teenagers to choose healthy food.

To explore the level of knowledge and demand for vaccination among parents of hospitalized premature infants in Chongqing, so as to provide reference for the development of targeted health education and early training programs in the future.

A purposive and cluster sampling survey was conducted from August to October 2023, using a self-designed questionnaire to investigate and analyze the vaccination awareness and needs of parents of premature infants hospitalized in 9 hospitals in Chongqing.

The overall awareness rate of parents of hospitalized premature infants was 79.28%, the awareness rate of routine vaccination knowledge was 85.80%, the awareness rate of vaccination knowledge of premature infants was 73.69%. Family upbringing history, education level, place of residence, economic income, and whether having received relevant training are the influencing factors of knowledge awareness. 25.46% parents of premature infants said that they would take their children for vaccination within one week after discharge. 85.06% parents thought that they were lack of vaccination knowledge. 88.41% parents thought that it was necessary to carry out vaccination health education for premature infants.

The vaccination knowledge level of parents of hospitalized premature infants in Chongqing needs to be improved, among which parents who have given birth to their first child, have low educational level, live in rural areas, have low family income and have not received vaccination knowledge training for premature infants are the key groups of health education and early training, and the timing and safety of vaccination are key points of training. It is an important way to train medical staff as the main body and combine various health education means.

To explore the relationship between female reproductive history and cognitive dysfunction in old age.

Based on the survey data of the Chinese Longitudinal Healthy Longevity Survey database in 2018, binary logistic regression and R4.3.3 software were used to construct a restricted cubic spline model to analyze the dose-response relationship between the number of births, gestational age and cognitive dysfunction in women.

7508 elderly women were included, of whom 764 (10.17%) had cognitive dysfunction. After adjusting for confounding factors, the first gestational age (OR=1.025, 95%CI:1.007-1.044), the last gestational age (OR=1.071, 95%CI:1.056-1.086), and the number of pregnancies (OR=1.085, 95%CI:1.044-1.127) had an impact on the cognitive function of elderly women. The results of the restricted cubic spline model showed that there was a linear dose-response relationship between the number of pregnancies and the risk of cognitive dysfunction in women (P_overall<0.05, P_{non-linearity}=0.67), and the cognitive function was not adversely affected when the number of pregnancies was ≤4 (OR<1, 95%CI:0.45-1). When she had only one child, there was a nonlinear dose-response relationship between the gestational age and the risk of cognitive impairment (P_overall<0.05, P_{non-linearity}<0.05), suggesting that the best childbearing age was 27 to 30 years old (OR<1, 95%CI:0.89-1). When she had more than one child, there was a nonlinear dose-response relationship between the first and last gestational age and the risk of cognitive impairment (P_overall<0.05, P_{non-linearity}<0.05), suggesting that the best childbearing age was 22 to 35 years old (OR<1, 95%CI: 0.99-1).

There is a correlation between female reproductive history and cognitive function in old age. Limiting the number of childbearing and encouraging age-appropriate childbearing can improve cognitive function in old age.

To analyze the co-morbidity of spinal curvature abnormality and myopia and the relevant factors in primary and middle school students in Guangzhou from 2019 to 2023, so as to provide references for the establishment of the mechanism of Co-morbidity, Shared Etiology, and Shared Prevention of common diseases in students.

From September 2019 to 2023, used stratified random cluster sampling, 4 248, 4 230, 4 266, 25 476, 25 587 primary and middle school students were selected as subjects for spinal curvature abnormality and myopia screening and questionnaire survey. The χ²test was used for comparing the group differences and univariate analysis. The multivariable logistic regression model was used to explore the influencing factors of their co-morbidity.

the co-morbidity rates of spinal curvature abnormality and myopia were 2.96%-6.00% from 2019 to 2023 in primary and middle school students in Guangzhou. The differences in the co-morbidity rates among students of each phases of studying and the difference of the co-morbidity rate in primary and middle school students over the past 5 years were statistically significant (P<0.05). Multivariate logistic regression analysis showed that low BMI junior and senior high school students (OR=1.72, 1.89, 95%CI: 1.11-2.67, 1.47-2.41) were more likely to suffer these two diseases. Primary school students in grades 4 to 6 who had menarche or spermatorrhea (OR=1.77, 95%CI: 1.04-3.02), screening time 2-<3h or≥3h per day (OR=3.06, 2.28, 95%CI: 1.41-6.68, 1.02-5.19), outdoor activities time<2h per day (OR=2.28, 95%CI: 1.22-4.26), junior high school students with low BMI (OR=1.72, 95%CI: 1.11-2.67), whose teacher "never or occasionally" reminded reading and writing posture (OR=1.50, 95%CI: 1.06-2.12), who were not strict with requiring standing and sitting posture themselves (OR=2.51, 1.99, 95%CI: 1.29-4.86, 1.06-3.74), senior high school students with low BMI (OR=1.89, 95%CI: 1.47-2.41) who had activities in the teaching building during recess (OR=1.33, 95%CI: 1.02-1.75), distance from chest to the edge of table "never or occasionally" more than 1 fist away during reading and writing (OR=1.27, 95%CI: 1.05-1.53) had a higher risk of spinal curvature abnormality and myopiaco-morbidity (P<0.05).

The co-morbidity of spinal curvature abnormality and myopia was associated with daytime outdoor exercise and sedentary behavior with bad posture. Early screening and early treatment of spinal curvature abnormality and myopia should be strengthened among adolescent students, especially in urban, female and emaciated students.

To assess the body mass index (BMI), percentage of body fat (PBF), and bone age of school-age children in Xuzhou city, and to explore the relationship between BMI, PBF, and bone age, so as to provide reference for promoting the health of children.

A cluster sampling method was used to select 601 students of grade three from three schools in Xuzhou from July to August 2023, questionnaire surveys and physical examinations were used to collect children’s data, and disordered multi-classification logistic regression analysis was used to explore the association between different types of BMI or PBF and bone age development.

The rates for thinness, overweight, and obesity in boys were 14.2%, 11.1%, and 19.2% respectively, in girls were 17.6%, 9.3%, and 14.0%, respectively; Multivariate logistic regression showed that after adjusting for covariates such as gender, development of secondary sexual characteristics, average monthly household income, birth weight, father’s height, and mother’s height, the risk of early bone age development was significantly increased in both the BMI obese and overweight groups compared to the BMI normal group (OR=10.10, 95%CI:4.83-21.12; OR=3.78, 95%CI:1.53-9.33); The PBF high body fat group had a significantly increased risk of early bone age development compared to the PBF normal group (OR=3.79, 95%CI:2.01-7.13); BMI obese and PBF high body fat groups are protective factors for delayed bone age development (OR=0.40, 95%CI: 0.20-0.78; OR=0.52, 95%CI:0.31-0.87).

Overweight and obese children are prone to premature bone age. It is recommended to regularly monitor weight, bone age and body composition while preventing and controlling overweight and obesity in children.

To establish an evaluation index system of medical service capacity in county hospitals, so as to provide a reference basis for further evaluating the overall medical service strength of county-level hospitals.

Experts were invited to evaluate the relative importance of indicators at all levels of medical service capacity, and the weights of the dimensions of the indicators system were determined using analytic hierarchy process.

A total of 35 experts were invited to consult letter inquiries, and the recovery rate of the questionnaire was 94.43%. The CR of first-level indicators judgment matrix was 0.0223, and the CR of the second-level index judgment matrix under the three dimensions of structure, process and outcome were 0.0000,0.0741and 0.0052, all less than 0.1. Finally, the evaluation index system included 3 first-level indicators, 10 second-level indicators and 23 third-level indicators. The highest weight of the first-level indicators was the result(0.4570). Among the combined weights there were 11 indicators that exceeded the average weight of 0.0435 (1/23).

The evaluation index system of county hospitals based on analytic hierarchy process is objective and reliable, which can provide reference for health administrative departments at all levels and county hospitals to carry out medical service ability evaluation and ability improvement according to the actual situation.

To observe the level and effect of medical insurance for five sites of cancer in China using an area of Anhui Province as an example.

Using the district’s Medicare billing list data for the three-year period 2019-2021. Based on the concepts of actual compensation ratio, bottom-line compensation ratio and catastrophic health expenditure, the level and effect of medical security were calculated by level, cost and level of medical institution, etc.

Overall, the out-of-pocket share of the patients was maintained at around 30%, the out-of-pocket share of patients with high medical expenses was small (16.59%). The level of tertiary medical institutions’ actual compensation ratio was low (65.81%-70.52%), but overallit still exceeded the bottom-line compensation ratio under the 40% and 25% catastrophic health expenditure standards.

The multi-level health insurance system has begun to bear fruit. There is a need to equalize the protection for different types of illnesses, to strengthen the hierarchical diagnosis and treatment, and to pay further attention to the needs of patients with “serious illnesses and light treatment”.

To explore the influence of social networks on health-related behaviors in stroke patients.

From July to September 2023, participants living in Guangdong were selected as the survey respondents using convenient sampling method. The general information questionnaire, stroke health-related behavior questionnaire and social network questionnaire were used to collect data. Social network analysis was used to explore network characteristics and draw social network diagrams. Latent class analysis was used to explore health-related behavior patterns of stroke. Kruskal-Wallis H test and Bonferroni test were used to compare the differences in social networks of different health-related behavior patterns.

Stroke health-related behaviors can be divided into three categories, namely "good health behavior group" (C1, 58.15%), "smoking and drinking group" (C2, 24.60%), and "sedentary lifestyle and imbalanced diet and sleep group" (C3, 17.25%). The network effective size, efficiency, and betweenness centrality of the "smoking and drinking group" and the "sedentary lifestyle and imbalanced diet and sleep group” were lower than that of the "good health behavior group" (P<0.05/3). In contrast, the density, network hierarchy, network constraint, percentage of individuals who smoked and drank, and percentage of individuals who did not exercise and ate healthily of the two groups were higher than that of the "good health behavior group" (P<0.05/3).

Social network characteristics with high betweenness centrality, low hierarchy, low constraint and high network efficiency can promote health-related behaviors of stroke. Building a social network with equality, low constraint and positive healthy interaction is helpful for community stroke prevention and treatment.

To analyze the impact of nighttime sleep duration on depressive symptoms in the lifestyle habits of elderly people with multiple comorbidities in China.

Using the fifth round of the China Health and Retirement Longitudinal Study project, the depression mood of elderly people with multiple comorbidities was evaluated based on the Center for Disease Control Depression Rating Scale (CSE-D-10). Nighttime sleep was divided into five levels:<6 h, 6 to <7 h, 7 to <8 h, 8 to <9 h, and ≥9 h. Multivariate logistic regression analysis was conducted to investigate the influencing factors of depression in elderly people with multiple comorbidities. Random forest model was used to analyze the importance of nighttime sleep in the risk of depression in elderly people with multiple comorbidities. Restrictive cubic spline curves were used to further explore the dose-response relationship between nighttime sleep duration and the risk of depression.

A total of 1 249 elderly individuals with multiple comorbidities were included, aged (68.51±5.91) years. Multivariate logistic regression analysis showed that the risk of depression in elderly individuals with multiple comorbidities who slept at night for 6 to <7 hours (OR=0.447 (95%CI: 0.309-0.646)), 7 to <8 hours (OR=0.550 (95%CI: 0.351-0.862)), and 8 to <9 hours (OR=0.498 (95%CI: 0.323-0.768)) was relatively lower compared to those who slept for less than 6 hours. Discomfort caused by pain, ADL, life satisfaction, and stroke are the influencing factors for depression in elderly people with multiple comorbidities (P<0.05). The results of the random forest model show that the importance score of nighttime sleep on depression symptoms is relatively high. The results of the restricted cubic spline curve indicate a non-linear relationship between nighttime sleep and the risk of depression symptoms. The risk of depression symptoms decreases with 6-8 hours of nighttime sleep, and increases with less than 6 hours or more than 8 hours of nighttime sleep.

Nighttime sleep has an impact on the occurrence of depression in elderly people with multiple comorbidities. It is recommended that elderly people maintain 6-8 hours of nighttime sleep to effectively reduce the risk of depression and have certain significance for early prevention and control of depression in the elderly population.

To explore the relationship between social media addiction and anxiety among college students and the role of bedtime procrastination and stress perception.

A total of 15493 college students were selected by convenience sampling in September 2023 with using the Bergen Social Networking Addiction Scale, the Bedtime Procrastination Scale, the Chinese Perceived Stress Scales and the Generalized Anxiety Disorder 7-item Scale. SPSS25.0 macro program PROCESS was used to analyze the mediating effect of bedtime procrastination and the moderating effect of stress perception.

The social media addiction was positively predicted college students’ anxiety (β=0.307, P<0.001). Bedtime procrastination partially mediated the relationship between social media addiction and anxiety in the college students. The mediation effect value was 0.060 (95% Bootstrap CI=[0.055-0.065]), the mediating effect accounted for 19.54% of the total. Stress perception moderated the relationship between bedtime procrastination and anxiety (β=0.094, P<0.001). As the level of perceived stress increased, the positive association between bedtime procrastination and anxiety became stronger.

Social media addiction can directly affect anxiety in the college students, or indirectly affect it through bedtime procrastination, and perceived stress moderates the path from bedtime procrastination to anxiety in the mediation model.

To evaluate the information quality of hypertension-related videos on the TikTok short video platform and assess their potential value for public health education.

In June 2024, we searched the TikTok short video platform using the keyword "hypertension" selecting the top 200 videos and ultimately including 177 videos for quality evaluation. Structured content integrity assessment tools and the DISCERN video quality assessment tool were used to evaluate the videos. The correlation between video quality and characteristics (duration, likes, comments, favorites, and shares) was studied.

The 177 videos received 11 250 432 likes, 366 588 comments, 3 265 929 favorites, and 3 780 513 shares. The median video length was 111 seconds (74, 158), and the median upload days were 672 days (147, 878). 89.3% of the videos were posted by doctors, 8.5% by individual science communicators, and 2.3% by news agencies. 98.9% of the videos had subtitles, all featured individuals, and only 26.0% included animated demonstrations. Content integrity scores were: definition 0.19±0.40, symptoms 0.11±0.32, risk factors 0.29±0.50, assessment 0.36±0.45, management 0.81±0.47, and outcomes 0.63±0.58. 90.4% of the videos had a DISCERN score of ≤50, indicating "average" or below quality, with no significant difference in DISCERN scores among different publishers (P>0.05). DISCERN scores were significantly correlated with video duration (r=0.409, P<0.001).

The overall quality of hypertension-related videos on TikTok is low, with a significant positive correlation between video duration and quality. High-quality videos receive less attention, making TikTok an unsuitable platform for hypertension education due to low information quality and reliability.

To analyze the participation of mutual help and pension and influencing factors of the elderly in China, and to provide a reference basis for the long -term development of mutual help.

Based on the China Longitudinal Aging Social Survey (CLASS) data, single -factor deck analysis, non-conditional logistic regression and Shapley decomposition method was used to analyze the influencing factors and differences in the participation of the elderly people in my country.

The participation rate of mutual support for the elderly in China was only 19.72%, the participation level was low, and the awareness of mutual support for the elderly was weak. Multivariate Logistic regression results showed that the participation of the elderly in mutual support for themwas affected by the demographic characteristics, personal physical conditions, family conditions, pension concepts and ways. Shapley decomposition showed that the contribution rate of each factor to the elderly’s participation in mutual support for the elderly was different, and the physical condition of the elderly had the greatest impact on their participation in mutual support for the elderly, the contribution rate was 19.96%. The second was the participation in insurance and the need for help from others, with the contribution rates of 19.27% and 12.33% respectively.

It’s of great importance tocreate a platform for mutual assistance for the elderly, improve the government incentive mechanism, improve the community support network, and create a good atmosphere of mutual assistance, strengthen mutual assistance pension and education, and play a role of family support.

To investigate the role of ferroptosis in striatum damage induced by combined exposure of microplastics and manganese by establishing a mouse model following microplastics and manganese alone or combined exposure.

Forty SPF male C57 mice were randomly divided into control group, manganese exposure group, microplastics exposure group and combined exposure group. Neurobehavioral tests including rotarod test, open field test and sucrose preference test were performed. The contents of divalent iron, malondialdehyde and glutathione in striatum of mice were detected by using the kit. Western blotting was used to detect the protein expressions of SLC7A11, GPX4 and FPN1 in striatum of mice. Real-time PCR was performed to detect the expression of miR-124. Single factor analysis of variance was used for comparison of multiple groups of data, and LSD test was used for further pairwise comparison.

Behavioral tests showed that the residence time of the rotating rod (all P<0.001), the residence time in the central zone of open field test (all P<0.001), total distance of open field test (all P<0.001) and the sucrose preference rate (P_manganese=0.010; P_{microplastics}<0.001) in manganese exposure group and microplastics exposure group decreased significantly compared with that of the control group. Compared with the manganese exposure group and microplastics exposure group, the residence time of the rotating rod, the residence time in the central zone of the open field test and the total distance of the open field test of combined exposure group decreased significantly (all P<0.001). In addition, the sucrose preference rate of the combined exposure group was lower than that of the manganese exposure group (P=0.001). At the same time, compared with the control group, the contents of Fe²⁺ in striatum of mice in manganese exposure group and microplastics exposure group increased (P_manganese=0.002; Pmicroplastics=0.001), the contents of GSH decreased (P_manganese=0.015; Pmicroplastics<0.001). The content of MDA in the striatum of mice in microplastics exposure group increased (P<0.001). Furthermore, the contents of Fe²⁺ and MDA in striatum of mice in combined exposure group were higher than those in manganese exposure group (P_Fe²⁺=0.004; P_MDA<0.001) and microplastics exposure group (P_Fe²⁺=0.008; P_MDA=0.007), while the content of GSH was lower than that in the manganese exposure group (P<0.001). The protein expressions of SLC7A11 in manganese exposure group (P=0.010) and microplastics exposure group (P=0.001) were lower than that in the control group. The protein expression of GPX4 in microplastics exposure group was lower than that in the control group (P=0.007), and the protein expression of GPX4 in the combined exposure group was lower than that in the manganese exposure group (P=0.006). The protein expressions of FPN1 in the manganese exposure group (P=0.005) and microplastics exposure group (P=0.002) were lower than that in the control group and the protein expression of FPN1 in the combined exposure group was significantly lower than those in the manganese exposure group (P=0.008) and microplastics exposure group (P=0.005). Compared with the control group, the expressions of miR-124 in striatum of mice in manganese exposure group (P=0.002) and microplastics exposure group (P<0.001) increased. At the same time, the expression of miR-124 in the striatum of mice in the combined exposure group was higher than those in the manganese exposure group and microplastics exposure group (all P<0.001).

Combined exposure of microplastics and manganese might lead to striatum damage in mice through the regulation of ferroptosis, and then cause motor dysfunction and anxiety-depression-like behavior.

To study the effects of superfine grinding treatment on the composition and efficacy of loquat branches.

After the loquat branches were superfine grinding treated, the contents of total phenols, total flavonoids, polysaccharides, ursolic acid, oleanolic acid in the extracts from loquat branches with different particle sizes were detected by spectrophotometry and high-performance liquid chromatography. The in vitro antioxidant capacity of extracts from superfine loquat branches was evaluated by DPPH, ABTS free radical scavenging assay and FRAP assay. SPF-grade male Kunming mice were randomly divided into blank/model control group, drug group, loquat leaf control group, and low, medium, and high dosage of superfine loquat branches according to their body weights. The expectorant effect of extracts from superfine loquat branches was evaluated by phenol red excretion assay, and the antitussive effect of extracts from superfine loquat branches was evaluated by ammonia-induced cough assay.

The total phenol, total flavonoid and oleanolic acid contents of the three particle size loquat branch groups were higher than those of the branch control group (P<0.05, P<0.01), the total phenol and total flavonoid contents of the 220-mesh and 400-mesh loquat branch groups were higher than those of the leaf control group (P<0.05), and the ursolic acid contents of the 220-mesh and 400-mesh loquat branch groups were higher than those of the branch control group (P<0.01). In the in vitro experiment, the DPPH IC₅₀ and ABTS IC₅₀ of the three particle size loquat branch groups were lower than that of the branch control group (P<0.05), and the FRAP value was higher than that of the branch control group (P<0.05), and the DPPH IC50 and ABTS IC50 of the 200 mesh and 400 mesh loquat branch groups were lower than that of the leaf control group (P<0.05), and the FRAP value was higher than that of the leaf control group (P <0.05). In the phenol red excretion experiment, the phenol red excretion was significantly elevated in mice in the high-dose superfine loquat branch group (P<0.05). In the ammonia-induced cough experiment, both medium-dose and high-dose superfine loquat branches groups prolonged the latency period of coughing and the number of coughs in mice (P<0.05).

Appropriate superfine grinding treatment can increase the content of the efficacy components of loquat branches, enhance their antioxidant effect, and at the same time, they have certain expectorant and antitussive effects.

To investigate the relationship between total cholesterol (TC) levels, snoring condition with Metabolic Syndrome (MetS) in a population of 30-79 years old from the Dong ethnic minority in Guizhou Province, and to further analysethe interaction between the two on MetS.

The data of this study came from the database of the “Natural Population Cohort Study in the Gathering Places of Ethnic Minorities in Southwest China”, and a total of 5 815 people of Dong ethnic group aged 30-79 years in Guizhou Province were included, and used binary logistic regression to analyse the associations of TC level and snoring condition with MetS, respectively. A multiplicative model and an additive model were constructed for assessing the association of the interaction between TC level and snoring condition with MetS.

The detection rate of metabolic syndrome was 22.08% in the population of the hereditary Dong ethnic group aged 30-79 years in Guizhou Province. In the total population, TC levels ≥5.20 mmol/L were found to be positively associated with MetS compared to participants with TC levels <5.20 mmol/L (OR=2.19, 95%CI: 1.93-2.49). In addition, snoring was positively associated with the MetS prevalence (OR:2.17, 95% CI:1.19-2.47). There was no multiplicative but additive interaction between TC level and snoring condition on MetS in the total population (the relative excess risk due to interaction=1.10, 95% CI: 0.41-1.79; the attributable proportion due to interaction=0.25, 95% CI: 0.12-0.39; the synergy index=1.49, 95% CI: 1.15-1.92).

In the prevention and control of MetS, attention should be paid not only to biochemical indicators such as TC levels, but also to the effect of snoring on the disease. By cultivating a healthy lifestyle, TC levels can be reduced and snoring can be improved with a view to playing a positive role in the management and control of MetS.

To explore the differences in the status of co-morbid combinations and health-related quality of life between urban and rural middle-aged and elderly people, and to provide a reference for improving the health of middle-aged and elderly people with co-morbid combinations of chronic diseases.

A total of 6 481 middle-aged and elderly people aged ≥50 years with at least two chronic diseases in China Healthy Aging and Reproductive Lifestyle Survey (CHARLS) 2020 were selected. The basic characteristics of urban and rural chronic disease co-morbid middle-aged and elderly people were described, the health-related quality of life was evaluated using the health utility value of EQ-5D-3L, and the combination of urban and rural chronic disease co-morbid combinations was analyzed using the association network diagram and Apriori association rule.

The health utility value of the elderly in urban chronic disease co-morbidities was 0.8532±0.2400, which was higher than that of the elderly in rural chronic disease co-morbidities (0.8409±0.1952). The top five urban strong link chronic disease co-morbidity combination weights were: hypertension+dyslipidemia; hypertension+heart disease; hypertension+arthritis; gastric disease+arthritis; dyslipidemia+heart disease. In rural areas, there were: gastric disease+arthritis; hypertension+arthritis; hypertension+dyslipidemia; and hypertension+gastric disease. Chronic disease co-morbidities in rural middle-aged and elderly people produced 105 association rules and 86 association rules in urban. Among the top 10 association rules in terms of strength of association rules, there were 9 association rules for hypertension and 1 association rule for chronic lung disease in the rural posterior, while there were 6 association rules for hypertension, 3 association rules for dyslipidemia and 1 association rule for chronic lung disease in the urban posterior.

Health related quality of life of elderly people with chronic disease co-morbidities was higher in urban than in rural areas, with emphasis on pain management and depression and anxiety management in elderly people with chronic disease co-morbidities. There are differences in the combination of chronic disease co-morbidities in urban and rural areas, and the binary, ternary, and quaternary co-morbidity associations between common chronic disease illnesses are high, and hypertension and other chronic diseases and co-morbidities are the highest, and attention should be paid to preventive treatment of hypertension.

To analyze the late diagnosis of newly reported HIV/AIDS in Hebei province from 2016 to 2022, and to understand the proportion of late diagnosis of HIV/AIDS and its influencing factors.

The information of newly reported HIV/AIDS cases in Hebei province from 2016 to 2022 was collected through the national basic information system of HIV/AIDS, and identified relevant cases by definition of late diagnosis. Trend Chi-square test was used to analyze the changing trend of late diagnosis proportion, the influencing factors of late diagnosis were analyzed by Chi-square test and Logistic regression model.

From 2016 to 2022, 14 689 HIV/AIDS cases were newly reported in Hebei province, and the proportion of late diagnosis was 33.1%. The proportion of late diagnosis showed an upward trend in each year (χ²=69.826, P<0.001). The results of Logistic regression showed that the proportion of late diagnosis was higher in the farmers, the source of testing consulting and medical institutions and other, and the higher age group. The OR (95%CI) of farmers was 1.154 (1.021-1.303) compared with the household workers, and the unemployed. Compared with the custodial population, the OR (95%CI) of testing counseling and medical institutional and other sources were 1.909 (1.236-2.949), 3.205 (2.08-4.938) and 1.808 (1.136-2.875). The OR (95%CI) of each age group was 1.945 (1.469-2.577), 3.279 (2.458-4.375), 3.996 (2.97-5.377), 5.223 (3.87-7.05) and 5.202 (3.814-7.095), respectively. The proportion of late diagnosis varies greatly in different cities, City 5, City 11 and City 1 was higher than the average of the whole province.

From 2016 to 2022, the proportion of late diagnosis HIV/AIDS cases in Hebei province is increased in each year, and there are big regional differences. Occupation, sample source and age are the influential factors of late diagnosis, targeted measures should be taken to prevent and improve the ability of early detection.

To analyze herpes zoster vaccine (HZV) vaccination intention and influencing factors among people aged 40 years and above.

A stratified sampling method was used to select people aged ≥40 years from 6 streets of 3 districts in Nanjing for a questionnaire survey. Multivariate Logistic regression model was used to analyze the influencing factors of HZV vaccination intention.

Among those who had not been vaccinated with HZV, 27.00% (385/1 426) were willing to receive HZV vaccination. High income region (OR=1.53,95%CI:1.05-2.21), employee basic medical insurance (OR=1.52,95%CI:1.02-2.27), per capita monthly household income >10 000 yuan (OR=2.15,95%CI:1.26-3.67), currently or before retirement engaged in health care (OR=1.86,95%CI:1.05-3.30), self-assessed good or very good health status (OR=3.27,95%CI:1.50-7.09), family history of HZ (OR=1.93,95%CI:1.37-2.71), influenza vaccine immunization history (OR=2.53,95%CI:1.66-3.84), HZV willingness to pay >1 000 yuan (OR=2.49,95%CI:1.44-4.30), perceived susceptibility (OR=1.17,95%CI:1.02-1.34), and self-efficacy (OR=1.59,95%CI:1.28-1.96) were the influencing factors to promote the HZV vaccination intention.

The willingness rate of HZV vaccination in people ≥40 years old in Nanjing is low. Health education about Herpes zoster (HZ) and HZV should be strengthened, especially the susceptibility of HZ and the safety of HZV. According to the characteristics of HZV vaccination recipients, vaccination agencies can take various ways to publicize vaccination service information and optimize the vaccination process such as appointment and payment. Relevant departments should explore HZV immunization strategies to reduce the economic burden of HZV vaccination.

To investigate the relationship between stress-induced hyperglycemia in acute pancreatitis (AP) patients and the risk of developing new-onset diabetes after pancreatitis.

This study selected patients with acute pancreatitis (AP) who had no prior history of diabetes and were hospitalized in the Department of Gastroenterology at Nanjing Drum Tower Hospital, affiliated with Nanjing University, 2015-2019. New-onset diabetes after pancreatitis was diagnosed based on established criteria. The relationship between stress-induced hyperglycemia upon admission and the risk of developing new-onset diabetes was assessed using the COX proportional hazards model. Stratified analyses were conducted based on gender, age, education level, place of residence, marital status, smoking history, admission diagnosis, Body Mass Index (BMI), history of pancreatic necrosis/abscess, and severity of the condition.

This study included a total of 1258 participants. The follow-up incidence of diabetes was 28.3%. Patients who experienced stress-induced hyperglycemia upon admission had a higher risk of developing new-onset diabetes compared to those with normal blood glucose levels (HR=1.40, 95%CI:1.06-1.85). Subgroup analysis indicated that patients who were elderly(HR=2.01, 95%CI:1.19-2.12), male(HR=1.17, 95%CI:1.03-2.35), from rural areas(HR=1.37, 95%CI:1.24-1.53),had a history of smoking(HR=1.25, 95%CI:1.14-1.38), had a history of pancreatic necrosis/abscess(HR=1.34，95%CI:1.07-1.98), BMI≥28 kg/m ? (HR=2.33, 95%CI:1.57-4.553), or had moderate to severe pancreatitis(HR=1.45, 95%CI:1.27-2.58; HR=1.23, 95%CI:1.06-1.93), had a greater risk of developing new-onset diabetes if they experienced stress-induced hyperglycemia.

Stress hyperglycemia at admission is associated with an increased risk of new-onset diabetes after pancreatitis. Effective glucose management in high-risk AP patients with stress hyperglycemia may help reduce the risk of developing new-onset diabetes.

To explore the causal relationship between testosterone and endometriosis, andto identify and quantify the role of gut microbiota as a potential mediator through Mendelian randomization analysis.

Utilizing the summary data from the IEU GWAS database for testosterone (n=199 569) and endometriosis (8 288 cases and 68 969 controls) as the exposure and outcome variables, and the aggregated gut microbiota data from the MiBioGen Consortium (n=18 340) as the mediator, a bidirectional, two-step Mendelian randomization analysis was conducted. Causal relationships were assessed using inverse varianceweighted, MR-Egger, weighted median, weighted model, and simple modelto assess causality, while sensitivity analysis was conducted to ensure the robustness of the findings.

Impact of testosterone on endometriosis:Inverse variance weighted estimates suggested that testosterone had negative causal effects on endometriosis (OR=0.804, 95%CI:0.670-0.964, P=0.018).Impact of endometriosis on testosterone:Reverse Mendelian randomization showed that endometriosis did not present a causal effect on testosterone (OR=0.991, 95%CI:0.958-1.026, P=0.616).The class Melainabacteria, one of the gut microbiotas, accounted for a 17.21% reduction in the risk of endometriosis associated with testosterone (mediation proportion: 17.21%, 95%CI:0.090-0.264, P=0.035).

Testosterone is one of the protective factors of endometriosis.Low testosterone levels increase the risk of endometriosis.Gut microbiota may be a mediator of the causal effect of testosterone on endometriosis.

To understand the status of alexithymia in people living with HIV aged 50 years and over, and to analyze its influencing factors.

From November 2023 to March 2024, HIV-infected people aged 50 and over in Luzhou City, Ziyang City and Zigong City of Sichuan Province were selected by convenience sampling method. The 20-item Toronto Alexithymia Scale(TAS-20), Loneliness Scale(UCAL) and Montreal Cognitive Assessment Scale(MoCA) were used to conduct a questionnaire survey on people living with HIV aged 50 and over. T-test and ANOVA were used to compare the scores of alexithymia in HIV-infected people aged 50 years and above with different characteristics. Multiple linear regression analysis was used to explore the influencing factors of alexithymia in HIV-infected people aged 50 years and above.

The average scores of TAS-20, UCAL and MoCA were (61.93±10.99) points, (44.91±9.87) points and (18.56±4.86) points, respectively, in 207 HIV-infected patients aged 50 years and above. The detection rate of Alexithymia was 52.2%. The results of multivariate analysis showed that non-marriage (β=0.13,95%CI: 0.03-0.53), loneliness (β=0.44, 95%CI: 0.32-0.55), poor cognitive function (β=-0.25, 95%CI: -0.37-0.14) may be the influencing factor of alexithymia in HIV-infected persons aged 50 years and above.

Compared with other age groups, HIV-infected people aged 50 and above have a higher prevalence of alexithymia, and AIDS prevention and control managers should focus on unmarried, lonely and poor cognitive performance of infected people, to develop personalized interventions for them to alleviate alexithymia.

To analyze whether there is a threshold effect between thyroid hormone sensitivity indexes and breast cancer, and to analyze the subgroup analysis and interaction test of age.

2 892 adults from NHANES were collected between 2007 and 2012, including 83 breast cancer patients. Central thyroid hormone sensitivity indices were calculated, including Thyroid Feedback Quantile Index for T4(TFQI_FT4) and T3(TFQI_FT3), Thyroid Stimulating Hormone T4 Resistance Index(TT4RI), Thyroid Stimulating Hormone T3 Resistance Index(TT3RI), and TSH Index(TSHI), as well as peripheral thyroid hormone sensitivity index FT3/FT4. The association between breast cancer and the thyroid system was investigated using a multivariable logistic regression model. Smooth curve fitting and stratified analysis were used too, and subgroup analysis and interaction tests were performed based on age.

Model3 showed that Thyroid Stimulating Hormone (TSH) (OR=1.33, 95%CI:1.08-1.63), TFQI_FT4(OR=2.61, 95%CI:1.25-5.45), TFQI_FT3(OR=3.15, 95%CI:1.18-8.44), TT4RI(OR=1.03, 95%CI:1.01-1.05), TT3RI(OR=1.10, 95%CI:1.03-1.18), and TSHI(OR=1.68, 95%CI:1.14-2.50) were significantly positively associated with the risk of breast cancer. A linear relationship with breast cancer was observed when TFQI_FT3≥0.7, TSHI≥2.4, and TT4RI<50(P<0.05). TFQI_FT4 showed a threshold effect(likelihood ratio test=0.040) when TFQI_FT4<0.25. The relationship between TFQI_FT4 and breast cancer was not significant(OR=1.07, 95%CI:0.36-3.15), but when TFQI_FT4≥0.25, it was significantly associated with an increased risk of breast cancer(OR=12.79, 95%CI:2.50-65.40). Subgroup analysis further revealed that in women over 55 years old, increased central thyroid hormone sensitivity indices were associated with breast cancer risk(P<0.05).

Increased central thyroid hormone sensitivity indices are significantly associated with the risk of breast cancer, which may be a potential indicator for breast cancer detection in the future.

To analyze the training content needs and preferences of administrative personnel in a tertiary public hospital under the backdrop of high-quality hospital development, aiming to enhance their overall performance and effectiveness in supporting hospital growth.

This study utilized a questionnaire survey and employed chi-square goodness-of-fit test for statistical analysis.

A total of 70 questionnaires were collected. 84.29% of the respondents believed that the relevance of training content, 74.29% thought time conflicts, and 70.00% considered leadership attention, training participation awareness, and the competence of training instructors as the main factors affecting training quality. 65.71% of the respondents identified holistic thinking ability, 62.86% noted innovation capability, and 44.29% pointed out decision-making skills as the most needed training content.

The main factors affecting the quality of management ability training for hospital administrative staff are the relevance of training content and employees’ willingness to participate in training. The ability that needs the most training is communication skills, while the greatest demand is for knowledge about the hospital’s development history and culture. The optimal format is monthly offline lectures lasting 1-2 hours.