To investigate the effects of Buzhong Yiqi Decoction（补中益气汤）combined with Huaier Granules（槐耳颗粒）on swallowing function as well as inflammatory factors after esophageal cancer surgery.

Eighty-four patients with esophageal cancer who met the inclusion criteria were selected and divided into the reference group and treatment group according to the ratio of 1∶1 by random number table method. Both the reference and treatment groups received general treatment. The reference group was treated with traditional Chinese medicine placebo in combination with conventional western medicine. The treatment group was treated with Buzhong Yiqi Decoction combined with Huaier Granules on the basis of western medicine treatment for 2 weeks. The changes of TCM syndrome points，adverse reactions，swallowing function，the levels of C-reactive protein（CRP），interleukin-6（IL-6），interleukin-1β（IL-1β），squamous cell carcinoma antigen（SCC-Ag），carbohydrate antigen 19-9（CA19-9），carcinoembryonic antigen（CEA）and quality of life scores of the two groups were observed before and after treatment.

There was no significant difference between the two groups in all the observational indicators before treatment（P>0.05）. After receiving the treatment，all the indexes of the reference group and the treatment group improved（P<0.05）. And in the treatment group，the improvement of the TCM syndrome points，swallowing function，inflammatory factor levels and tumor marker level were more obvious，and the quality of life was significantly improved（P<0.05）.

The combination of Buzhong Yiqi Decoction and Huaier Granules can effectively improve the swallowing function and the effect of inflammatory factors after esophageal cancer surgery. Moreover，it can reduce the postoperative stress reaction of patients with esophageal cancer，decrease the levels of tumor markers and improve the quality of life of patients.

To explore the effects of Xionggui Zhitong Decoction（芎归止痛汤）combined with carbamazepine on pain，sleep，inflammatory factors and oxidative stress in patients with primary trigeminal neuralgia（PTN）.

A hundred cases of PTN patients were randomly divided into observation group and study group（50 cases in each group）. The two group were treated with carbamazepine，and the study group was treated with Xionggui Zhitong Decoction on the basis of carbamazepine. The changes of pain，sleep，inflammatory factors and oxidative stress before and after treatment were observed.

The present pain intensity score（PPI），pain rating index score（PRI）and visual analogue scale（VAS）score，Pittsburgh Sleep Quality Index（PSQI）score，the levels of serum substance P（SP），vasoactive intestinal peptide（VIP），tumor necrosis factor-α（TNF-α），interleukin-6（IL-6），interleukin-1β（IL-1β）and malondialdehyde（MDA）of the two groups after treatment were lower than those before treatment（P<0.05），the levels ofβ-endorphin（β-EP），superoxide dismutase（SOD）and glutathione peroxidase（GSH-Px）were higher than those before treatment（P<0.05）. After treatment，the scores of PPI，PRI，VASand PSQI scores，the levels of serum SP，VIP，TNF-α，IL-6，IL-1βand MDA in the study group were lower than those in the control group（P<0.05），and the levels ofβ-EP，SOD and GSH-Px in the study group were higher than those in the control group（P<0.05）. The therapeutic effect of the study group was better than that of the control group（P<0.05）.

Xionggui Zhitong Decoction combined with carbamazepine in the treatment of primary trigeminal neuralgia can help to improve the pain and sleep status of patients，reduce the levels of inflammatory factors and oxidative stress，and improve the clinical therapeutic effect.

To study the clinical effect of Anshen Jiaotai Yizhi Decoction（安神交泰益智汤）in the treatment of Parkinson's disease with sleep disorders and its effect on the levels of homocysteine（Hcy）and interleukin-1β（IL-1β）in patients.

110 patients with Parkinson's disease and sleep disorders were selected and divided into two groups，55 patients in the control group were treated with western medicine，and 55 patients in the observation group were treated with western medicine combined with Anshen Jiaotai Yizhi Decoction. After 2 weeks of treatment，the clinical efficacy，sleep quality，sleep structure index，related factor levels and adverse reactions were compared.

The total effective rate of the observation group（96.36%，53/55）was higher than that（83.64%，46/55）of the control group（P<0.05）. The Epworth sleepiness scale（ESS）scores after 2 weeks of treatment of the observation group was（7.92±1.83）points，and that of the control group was（9.14±2.11）points（P<0.05）. The sleep efficiency of the two groups increased，the sleep latency shortened，the number of awakenings decreased，the apnea hypopnea index（AHI）decreased，and the minimum oxygen saturation increased. The indexes of the observation group were significantly better than those of the control group［（78.89±6.20）%，（23.10±4.08）min，（1.97±0.56）times，（9.08±1.03），（89.15±5.80）% vs（73.39±6.14）%，（27.82±5.26）min，（2.75±0.67）times，（11.71±1.34），（86.30±5.52）%］（P<0.05）. The levels of serum Hcy and IL-1βin the two groups decreased，and the levels of the observation group were significantly lower than those in the control group［（1.01±0.06）mg/L，（8.90±1.85）pg/mL vs（1.20±0.06）mg/L，（10.13±1.91）pg/mL］（P<0.05）. The incidence of adverse reactions of the two groups had no significance（14.55%，8/55 vs 10.91%，6/55）（P>0.05）.

Anshen Jiaotai Yizhi Decoction has a better clinical effect in the treatment of Parkinson's disease with sleep disorders. It can significantly improve sleep status and regulate the neuroimmune inflammatory response in the brain. It is a safe and effective treatment plan and is worthy of application.

To explore the clinical effect of Modified Juanbi Decoction（蠲痹汤加减）combined with thunder-fire moxibustion at Dazhui（DU14）in the treatment of cervical spondylosis.

A total of 120 patients with cervical spondylosis（cold-dampness blocking collateral type）admitted from September 2022 to September 2023 were included in the study. The patients were divided into the conventional group and the traditional Chinese medicine group by random number table method，with 60 cases in each group. The conventional group was treated with Celecoxib Capsule，while the traditional Chinese medicine group was treated with Celecoxib Capsule and Modified Juanbi Decoction combined with thunder-fire moxibustion at Dazhui（DU14）. During the study，4 cases fell off in the conventional group and 3 cases fell off in the traditional Chinese medicine group. The data of each group，including clinical treatment efficacy，the traditional Chinese medicine syndrome scores（neck and shoulder pain and numbness，chest tightness，headache，nausea，upper limb heaviness，etc.）before and after treatment，serum the levels of transforming growth factor-β1（TGF-β1），interleukin-1β（IL-1β）and tumor necrosis factor alpha（TNF-α），the changes of cervical physiological curvature and pain scale（visual analog scale，VAS）scores，the cervical spondylosis（CASCS）scores and neck disability index（NDI）scores and adverse reactions were observed and compared.

The total effective rate of the traditional Chinese medicine group（96.49%，55/57）was higher than that of the conventional group（85.71%，48/56）（P<0.05）. After treatment，the TCM syndrome scores（neck and shoulder pain and numbness，chest tightness，headache，nausea，upper limb heaviness，etc.），the levels of TGF-β1，IL-1βand TNF-αand VASscores were all decreased in both groups，physiological curvature indexes of cervical vertebra were increased，CASCSscores and NDI scores were improved. The above indexes in the traditional Chinese medicine group were lower than those in the conventional group，and the physiological curvature of cervical spine was higher than that in the conventional group，CASCSscores and NDI scores were higher than those in the conventional group（P<0.05）. The adverse reaction rate of the traditional Chinese medicine group（1.75%，1/57）was lower than that of the conventional group（12.50%，7/56）（P<0.05）.

Modified Juanbi Decoction combined with thunder-fire moxibustion at Dazhui（DU14）in the treatment of cervical spondylosis（cold-dampness blocking collateral type）has good clinical effect，with improved symptoms and better cervical function recovery，and the treatment is safe and reliable.

To explore the clinical efficacy of Sangju Qingjie Decoction（桑菊清解汤）combined with symptomatic and supportive therapy including anti-infection，antipyretic therapy，fluid resuscitation and aerosol inhalation in children with lobar pneumonia.

A total of 198 children with lobar pneumonia were classified into two groups，each with 99 cases. The control group was given symptomatic supportive treatment such as anti-infection，antipyretic therapy，fluid replenishment and aerosol inhalation，while the observation group was given Sangju Qingjie Decoction on the basis of the control group. The levels of high-sensitivity C-reactive protein（hs-CRP），white blood cells（WBC），erythrocyte sedimentation rate（ESR），interleukin-6（IL-6），peak expiratory flow（PEF），forced respiratory volume in 1 second（FEV1）and FEV1 versus forced vital capacity（FEV1/FVC）were compared between the two groups before and after treatment. Meantime，the time of fever reduction，the disappearance time of cough，sputum and wheezing，and hospital stay length，clinical efficacy and adverse reaction rate were also observed in both groups.

The total efficacy rate in the observation group（97.98%，97/99）was higher than that in the control group（84.85%，84/99）with statistical difference（P<0.05）. The TCM syndrome scores including cough，wheezing，expectoration and wheezing yielded no statistical difference between two groups before treatment（P>0.05），and the scores were descended in two groups after treatment（P<0.05）. There were statistical difference before and after treatment in two groups（P<0.05）. After treatment，TCM syndromes score of the observation group was lower than that of the control group（P<0.05）. The observation group had descended time to fever reduction，cough disappearance，sputum disappearance，wheezing disappearance and hospital stay length compared with the control group（P<0.05）. The levels of IL-6，WBC，hs-CRPand ESR of two groups before treatment showed no statistical difference（P>0.05），and had statistical difference after treatment（P<0.05）. After treatment，the levels of IL-6，WBC，hs-CRPand ESR were lower in the observation group than those of the control group（P<0.05）. No statistical difference was found in FEV1，PEF or FEV1/FVC before treatment（P>0.05），while the post-treatment FEV1，PEF and FEV1/FVCdenoted statistical difference with those before treatment（P<0.05）. The three pulmonary function indicators were higher in the observation group than those of the control（P<0.05）. After treatment，the total adverse reaction rate was 5.05%（5/99）in the observation group，which was slightly lower than that of the control group（7.07%，7/99）（P>0.05）.

The application of Sangju Qingjie Decoction combined with symptomatic and supportive therapy including anti-infection，antipyretic therapy，fluid resuscitation and aerosol inhalation in children with lobar pneumonia can remarkably improve the clinical outcome in children by shortening the duration of treatment，cutting down the rate of adverse reaction，and improving lung function and the serum levels of inflammatory factors.

To study the changes in endothelin（ET），serum neuropeptide Y（NPY）and substance P（SP）in patients treated with Modified Jichuan Decoction（济川煎加味）combined with abdominal acupuncture for slow-transmitting constipation with Yang-deficiency of spleen and kidney.

Ninety-four patients with slow-transmission constipation（Yang-deficiency of spleen and kidney）were divided into two groups by using random number method. The two groups were given general treatment，such as regular life，balanced diet，appropriate participation in physical exercise，drinking more water，etc. The Mosapride group was treated with Mosapride，and the Jichuan Decoction group was given Modified Jichuan Decoction combined with abdominal acupuncture on the basis of the Mosapride group. The time of first defecation，constipation symptom scores（including difficulty in defecation，frequency，time and faecal character，feeling of falling and incompletion，abdominal distension），the points of the Patient's Assessment of Quality of Life Scale（PAC-QOL）for constipated patients and the changes of ET，nitric oxide（NO），NPY and SP were compared between the two groups.

The overall time to first defecation in the Jichuan Decoction group was statistically better than that in the Mosapride group（P<0.05）. There was no statistical significance when comparing the scores of constipation symptoms such as difficulty in defecation，frequency，time and faecal characteristics，feeling of incompleteness and abdominal distension before treatment between the two groups（P>0.05）. The constipation symptom scores of Jichuan Decoction group and Mosapride group were lower after treatment than before treatment，and the constipation symptom scores of Jichuan Decoction group were lower than those of Mosapride group after treatment（P<0.05）. There was no statistical significance in the comparison of ET，NO，NPY or SP before treatment between the two groups（P>0.05）. The levels of ET，NO and NPY decreased and the level of SP increased after treatment in the Jichuan Decoction group and the Mosapride group compared with those before treatment（P<0.05）. The level of SP was higher in the Jichuan Decoction group than that in the Mosapride group，and the levels of ET，NO and NPY were lower than those in the Mosapride group after treatment（P<0.05）. There was no statistical significance in the comparison of PAC-QOL score before treatment between the two groups（P>0.05）. The PAC-QOL scores of Jichuan Decoction group and Mosapride group were lower after treatment than those before treatment，and the PAC-QOL scores of Jichuan Decoction group were lower than those of Mosapride group after treatment（P<0.05）.

Modified Jichuan Decoction combined with abdominal acupuncture can regulate the expression levels of ET，NO，NPY and SPin patients with slow-transmitting constipation with Yang-deficiency of spleen and kidney，improve the symptoms of constipation，promote the initial defecation and improve the quality of life.

To study the effect of Qingfengteng Decoction（青风藤汤）on the changes of CXCchemokine ligand 13（CXCL13）and macrophage inflammatory protein 1α（MIP-1α）in patients with rheumatoid arthritis.

Seventy-eight patients with rheumatoid arthritis were selected and divided into two groups by using the random number method. The methotrexate group was given methotrexate tablets for treatment，and the Qingfengteng Decoction group added Qingfengteng Decoction for adjuvant treatment to analyse the effect of the two groups after treatment.

The comparison of morning stiffness time，twohanded grip strength，number of joint pressure pain and 20 m walking time in the two groups showed no statistical difference（P>0.05）. Comparing the two groups before and after treatment，morning stiffness time，the number of joint pressure pain and 20 m walking time decreased in both groups，and the morning stiffness time，the number of joint pressure pain and 20 m walking time were lower in the Qingfengteng Decoction group than those in the methotrexate group after treatment（P<0.05）. Hands grip strength was elevated in both groups，and hands grip strength was higher in the Qingfengteng Decoction group than that in the methotrexate group after treatment（P<0.05）. The comparison of CXCL13，MIP-1α，ESR and interleukin between the two groups showed no statistical difference（P>0.05）. Comparing the two groups before and after treatment，the levels of interleukin-21（IL-21），CXCL13，blood sedimentation rate（ESR），interleukin-27（IL-27），MIP-1αand interleukin-32（IL-32）were reduced in the two groups，and in the Qingfengteng Decoction group，they were all lower than those of the methotrexate group after treatment（P<0.05）. There was no statistically significant difference in disease activity score 28（DAS28）between the two groups（P>0.05）. Comparing the two groups before and after treatment，the DAS28 scores of both groups were reduced，and the score of the Qingfengteng Decoction group was lower than that of the methotrexate group after treatment（P<0.05）.

The adjuvant treatment of rheumatoid arthritis can inhibit the expression levels of CXCL13，MIP1αand ESR，reduce the inflammatory response and disease activity and relieve the clinical symptoms.

To compare the effects of fresh cut pieces and traditional pieces of Huangqin（Scutellariae Radix），providing scientific basis for quality control of Huangqin（Scutellariae Radix）pieces with different processing method.

Ultraviolet spectrophotometry（UV）and ultra-high performance liquid chromatography（UPLC）and other methods were used to determine the contents of 6 index components（baicalin，wogonoside，baicalein，wogonin，total flavonoids，alcohol-soluble extract）in 24 batches fresh cut and traditional pieces of Huangqin（Scutellariae Radix）from different producing areas as samples. The bivariate correlation analysis of Huangqin（Scutellariae Radix）pieces was conducted by SPSS22.0 software in terms of the content of alcohol-soluble extract，total flavonoids，baicalin，wogonoside，baicalein and wogonin.

The content of alcohol-soluble extract in 24 batches of Huangqin（Scutellariae Radix）fresh cut pieces were（46.44±0.06）%～（55.26±0.21）%，the contents of total flavonoids，baicalin，wogonoside，baicalein and wogonin were（215.90±0.14）～（288.87±0.21）mg/g，（150.10±0.34）～（199.40±0.19）mg/g，（27.72±0.04）～（39.85±0.15）mg/g，（2.45±0.00）～（8.63±0.01）mg/g，（0.56±0.00）～（2.43±0.01）mg/g，respectively. The contents of alcohol-soluble extract in 24 batches of Huangqin（Scutellariae Radix）traditional pieces were（44.69±0.04）%～（54.24±0.07）%，the contents of total flavonoids，baicalin，wogonoside，baicalein and wogonin were（214.16±0.14）～（286.08±0.00）mg/g，（155.82±0.08）～（197.62±0.18）mg/g，（28.16±0.02）～（38.24±0.00）mg/g，（2.11±0.02）～（5.84±0.03）mg/g，（0.43±0.00）～（1.24±0.00）mg/g，respectively. Compared with those in the traditional cutting pieces，the contents of baicalein and wogonin were higher in fresh cutting pieces，whereas that of baicalin was lower in the fresh cutting pieces. Comprehensive evaluation of Huangqin（Scutellariae Radix）pieces were positively correlated with the contents of total flavonoids with the baicalin and wogonoside，the baicalin with wogonoside，the baicalein with wogonin（<0.01）.

The processing technology of fresh cutting is feasible in the production of Huangqin（Scutellariae Radix）pieces.

To investigate the clinical effect of Jianpi Shugan Tongru Prescription（健脾疏肝通乳方）combined with low frequency pulse electrical stimulation in patients with postpartum lactation deficiency（syndrome of weakness of Qi and blood）.

A total of 96 patients with postpartum lactation deficiency（syndrome of weakness of Qi and blood）admitted from January 2022 to December 2023 were included in this grouping study. The grouping method was random number table method，and they were divided into control group and observation group according to different treatment methods. The patients in the control group（48 cases）were given low-frequency pulse electrical stimulation treatment. Those in the observation group（48 cases）were given low-frequency pulse electrical stimulation and Jianpi Shugan Tongru Prescription，and the data of patients in each group was compared，including the clinical efficacy，the changes in TCM symptom scores，the levels of estradiol（E2）and prolactin（PRL）before and after treatment，the changes in breast filling degree，lactation volume and milk quality score，breastfeeding status，treatment adverse reactions and treatment satisfaction rate.

Compared with those in the control group，the total effective rate and satisfaction rate were higher in the observation group（P<0.05）. The rate of exclusive breastfeeding in the observation group was higher than that in the control group（P<0.05）. There was 1 case of bitter mouth in the observation group and no adverse reaction in the control group（P>0.05）. The scores of TCM syndrome，the levels of E2 and PRL，breast filling degree，lactation volume and milk quality scores of both groups were not significant before treatment（P>0.05）. After treatment，all indexes of both groups were improved，and all indexes of the observation group were better than those of the control group（P<0.05）.

The combination treatment of Jianpi Shugan Tonglu Prescription and low-frequency pulse electrical stimulation for patients with postpartum lactation deficiency（syndrome of weakness of Qi and blood）has a more significant effect. After treatment，the symptoms of patients are improved. They can better secrete milk，improve the rate of exclusive breastfeeding，meet the needs of newborns and have fewer adverse reactions and higher safety，and the patients are more satisfied and recognized.