To analyze the spatial compatibility between maternal and child health beds and the needs of women and children in Jiangsu at the county scale.

Spatial autocorrelation was used to analyze the spatial distribution of bed resources and maternal and child population in maternal and child health institutions in Jiangsu Province, and the adaptability of bed resources to the supply and demand of maternal and child population was analyzed by clustering degree.

The population of women and children of childbearing age showed obvious spatial aggregation in all districts and counties of Jiangsu Province, mainly concentrated in Suzhou and Xuzhou.There were 122 maternal and child health care institutions in Jiangsu, including 12 tertiary institutions and 29 secondary institutions, with a total of 11 878 beds. It was worth noting that there were 41 districts and counties with 0 beds, of which Suzhou City accounts for 7 districts and counties. The number of beds per 1 000 women and children in Zhonglou District of Changzhou City was the highest, 2.7 per 1 000 women and children. From the perspective of concentration degree, the bed resources of 17 districts (17.89%) were adequate geographically, while those of 76 districts (80%) were scarce geographically.After considering the demand population, it was found that the supply was greater than the demand in 21 districts (22.11%) and that the supply was less than the demand in 74 districts (77.89%).

There are regional differences in the supply and demand adaptation of maternal and child health care resources in Jiangsu Province, so it is necessary to adjust the service scope of the region where the supply exceeds the demand, and increase the service capacity building.

To explore the impact of cultural activities (CA) and physical exercise (PE) on residents’ subjective well-being (SWB)and its mechanism.

Using the 2021 China Comprehensive Social Surveydata, the ordered logistic model and mediating effect model were used for empirical analysis.

CA and PE could significantly enhance residents’ SWB, and the effect of CA on enhancing SWB was greater than that of PE. CA had a relatively greater impact on SWB of women, elderly, and rural residents. PE had a relatively greater impact on SWB of young and urban residents. Health status, social networks, social trust and sense of fairness all played a mediating role in the relationship between CA and SWB. Social trust had the greatest mediating effect, followed by health status, social networks and sense of fairness. Health status, social networks, social trust and sense of fairness all played a mediating role in the relationship between PE and SWB. Health status had the greatest mediating effect, followed by social trust, social networks and sense of fairness.

The government should strengthen efforts to promote the development of culture and sports industry, so that the people can get better spiritual and cultural nourishment and physical and mental health improvement, and have bigger SWB.

To explore the mediating effect of quality of sleep and cognitive reserve in the association of depression and cognitive function among the community-dwelling older adults.

A total of 492 community-dwelling elderly in the Pudong New Area of Shanghai were selected by convenience sampling method and investigated with the general information questionnaire, 15-item Geriatric Depression Scale (GDS-15), Pittsburgh Sleep Quality Index(PSQI), Cognitive Reserve Index Questionnaire(CRIq), and Beijing version of the Montreal Cognitive Assessment(MoCA). SPSS 25.0 software was used to explore the mediating role of sleep quality and cognitive reserve.

Pearson’s partial correlation analysis showed the cognitive function of elderly was significantly positively correlated with the cognitive reserve scores (r=0.189,P<0.001), and negatively correlated with the depression scores and sleep quality scores (r=0.179 and -0.362, both P<0.001); depression scores were significantly negatively correlated with cognitive reserve scores (r=-0.152, P<0.01), and significantly positively correlated with sleep quality scores (r=0.185, P<0.001), after adjusting for significant covariates including age, marital status, economic income and BMI, the mediating analysis showed depression had a significantly negative directly effect oncognitive function (β=-0.297, P<0.001); depression also had an indirectly negative effect on cognitive function through the pathways: reducing sleep quality and diminishing cognitive reserve, with medication effect values (β=-0.019, P<0.001) both accounted for 5.69%.

Community-dwelling elderly with depression, sleep disorders, and lower cognitive reserve have poorer cognitive function. Depression may directly affect cognitive function, and may also have indirect effects on cognitive function in elderly by decreasing sleep quality and cognitive reserve.

To explore the effects of intervention based on planned behavior theory on disease cognition, exercise self-efficacy, and daily living ability in elderly patients with sarcopenia.

Using convenience sampling method, 124 elderly patients with sarcopenia were selected from Lishuiwan Community and Shuxiangyuan Community in Shijiazhuang City as the research subjects. Using the coin toss method, 62 elderly people from Lishuiwan community were included in the intervention group on a residential community basis, while 62 elderly people from Shuxiangyuan community were included in the control group. The intervention group implemented interventions based on the Theory of Planned Behavior, which included five aspects: behavioral attitude, support from important others, perceived behavioral control, behavioral intention, and behavior. The control group maintained their original lifestyle and the intervention duration was 12 weeks. Two groups of patients were evaluated using the Simplified Disease Cognitive Questionnaire, Exercise Self Efficacy Scale, and Daily Living Ability Scale before and 12 weeks after intervention.

Before intervention, there was no statistically significant difference in disease cognition, exercise self-efficacy, and daily living ability scores between the two groups of patients (P>0.05). After intervention, the elderly patients in the intervention group showed improvements in disease cognition, exercise self-efficacy, and daily living ability compared to the control group, with statistically significant differences (P<0.05).

Interventions based on planned behavior theory can improve the disease cognition level, exercise self-efficacy, and daily living ability of elderly patients with sarcopenia.

To identify the influencing factors of stroke in elderly patients with hypertension based on community health survey, and establish a nomogram prediction model according to the influencing factors.

In 2022, the multi-stage sampling method was used to select the residents of Zhengzhou City, Henan province who lived for more than half a year for community health survey, and univariate and multivariate analysis was used to screen the influential factors of elderly hypertension patients complicated with stroke, and a nomogram prediction model was constructed. ROC curve, calibration curve and DCA decision curve are used to verify the accuracy and stability of the nomogram model.

A total of 15 995 elderly patients with hypertension were included in this study. The original data set was randomly divided into a training set and a validation set at 7:3. Model construction: The results of binary logistics analysis of the training set showed that age, gender, waist circumference, blood pressure control, overweight or obesity, exercise, smoking, drinking, balanced diet, dyslipidemia and heart disease were independent influencing factors for stroke. A nomogram model was constructed according to the results of multi-factor analysis. Model validation: the area under the ROC curve of the training set and the verification set is 0.748\0.779 respectively, and the calibration curve is well fitted, indicating that the model has good predictive value.

In this study, we established a nomogram prediction model for elderly hypertensive patients with stroke, including demographic characteristics, health status and lifestyle. The model is accurate and stable, which can help to screen high-risk individuals, provide clinical decision-making and prevention recommendations.

To explore the association between blood lipid, lipid ratios and glucose metabolism disorders, and to explore the dose-response relationship between lipid ratios and glucose metabolism disorders.

During July 2022 to March 2023, a total of 7 527 residents aged 35 and above in Changzhou were selected. basic information, blood pressure, fasting plasma glucose and blood lipid of the subjectswere collected. Binary logistic regression was used to explore the correlation between prediabetes, diabetes and blood lipid, lipid ratios, respectively. The dose–response relationship was evaluated by restricted cubic spline analysis. ResultsOur results showed that TC, LDL-C, TC/HDL-C, TG/HDL-C, LDL-C/HDL-C and non-HDL-C/HDL-C were risk factors for both prediabetes and diabetes (P<0.05), and HDL-C was a protective factor for both prediabetes and diabetes (P<0.05). The dose-response relationships between TC/HDL-C, TG/HDL-C, LDL-C/HDL-C, non‐HDL-C/HDL-C and glucose metabolism disorders were statistically significant, and the cutoff values were 3.78, 1.07, 2.10 and 2.77, respectively.

TC/HDL-C, TG/HDL-C, LDL-C/HDL-C and non‐HDL-C /HDL-C increase the risk of prediabetes and diabetes, which may be useful indicators to identify future glucose metabolism disorders.

To explore the association between HIV testing frequency and pre - / post-exposure prophylaxis (PrEP/PEP) use among individuals at risk of HIV.

Utilizing a follow-up cohort of men who have sex with men (MSM) conducted in five cities (Nanning, Liuzhou, Guilin, Yulin, and Beihai) in Guangxi Province, China, we employed a group-based trajectory model (GBTM) to analyze the developmental trajectories of HIV testing frequency among MSM. Furthermore, we conducted logistic regression analysis to examine the factors associated with different trajectory groups of HIV testing frequency and their relationship with the utilization of PrEP/PEP before and after HIV exposure.

The analysis included a total of 327 MSM participants, with an average age of 27.722±8.137 years. Based on evaluation criteria such as the Bayesian information criterion, GBTM identified three trajectory groups of HIV testing frequency: low-frequency group (73.87%), medium-frequency group (19.75%), and high-frequency group (6.37%). Comparing to the low-frequency group, MSM in the high-frequency group exhibited higher utilization rates of PrEP (9.49% vs. 55.56%) (χ²=32.02, P<0.001) and PEP (17.39% vs. 44.44%) (χ²=8.19, P<0.017). After controlling for relevant confounding factors, the low-frequency group and medium-frequency group showed of the used PrEP by OR=0.153 (95%CI:0.047-0.501, P=0.002) and OR=0.251 (95%CI:0.070-0.907, P=0.035), respectively, compared to the high-frequency group. Furthermore, regarding the frequency of HIV self-testing in the past year, as HIV testing frequency decreased, there was an increase in the frequency of HIV self-testing in the past year (low-frequency group OR=5.664, 95%CI:1.313-24.428, P=0.020) (medium-frequency group OR=5.087. 95%CI:1.082-23.926, P=0.039).

MSM who engage in higher-risk sexual behaviors are more likely to undergo regular and frequent HIV testing, and they are more proactive in using PrEP/PEP for HIV prevention. Compared with MSM with higher frequency of regular HIV testing, MSM with lower frequency of HIV testing showed higher rates of self-testing.

To understand the trends and factors associated with newly reported HIV and syphilis infections among men who have sex with men (MSM) in Nanning city, and provide a reference for developing targeted prevention strategies for the MSM population.

A questionnaire survey was conducted among MSM people in Nanning, Guangxi from 2019 to 2023, and venous blood samples were collected to detect HIV, HCV and syphilis. The trend chi-square test was used to analyze the trends of newly reported HIV,syphilis, and self-reported sexually transmitted infections prevalence. Logistic regression was employed to identify factors associated with newly reported HIV and syphilis infection.

A total of 1,954 MSM participated in the survey. The prevalence of newly reported HIV and syphilis were 3.8% and 4.6%. Respectively, there was a significant decline in newly reported HIV prevalence, from 6.8% in 2019 to 2.5% in 2023 (，trend P<0.05), while newly reported syphilis prevalence increased from 1.8% to 11.1% during the same period (, trend P<0.05). The study identified several factors associated with newly reported HIV infection, including lower education levels (aOR=1.70,95%CI:1.04-2.77) and inconsistent condoms use during anal intercourse (aOR=10.11, 95%CI: 5.94-16.89). Lower education levels (aOR=2.74, 95%CI: 1.71-4.38), a history of drug use (aOR=6.96, 95%CI: 1.42-34.19), and a history of self-reported sexually transmitted diseases (aOR=10.37, 95%CI:5.79-19.89) were found to be associated with newly reported syphilis infection. aged ≥30 (aOR=0.50, 95%CI:0.31-0.81)was identified as a protective factor against syphilis infection.

The prevalence of newly reported HIV was a downward trend, but the trend of newly reported syphilis prevalence showed an upward trend among MSM in Nanning, 2019-2023. The study suggests that relevant health departments need to take targeted intervention measures for the MSM population in conjunction with the internet, improve the usage rate of condoms, and strengthen the regulation of drugs and pharmaceuticals.

To conduct a comparative analysis of the research topics on home and international chronic disease management from 2013 to 2023, aiming to provide valuable insights for future studies.

The Chinese databases selected for this study were CNKI, Wanfang Database, and Sinomed, while the English database chosen was Web of Science core dataset. EndNote 20 software was utilized to gather literature on "chronic disease management", and visual analysis was conducted using VOSviewer and CiteSpace software.

A total of 6 621 Chinese articles and 4 096 English articles met the inclusion criteria. Over the course of the decade, there was a consistent upward trend in the number of articles pertaining to home-based chronic disease management both domestically and internationally. According to the co-occurrence cluster analysis, six clusters were identified in China for the management of chronic diseases, including community-based comprehensive disease management, common chronic disease management, self-management of chronic diseases, pharmaceutical care for chronic disease management, health education for chronic disease management, and traditional Chinese medicine-based prevention and treatment of chronic diseases. Abroad, there were also 6 cluster themes identified: Health-care of chronic diseases, Regional trends and management of chronic diseases, The impact of emergencies, Major chronic diseases, Quality of life for patients with chronic diseases, Multiple chronic diseases.

Foreign research is more sensitive to current affairs and frontier hotspots. Domestic research is based on domestic specific forms, which is more in line with the national conditions and has localized characteristics. Chronic disease management in China should continue to deepen the research on basic chronic disease management and chronic diseases in the elderly and other topics that fit the reality, and further develop the prevention and treatment of traditional Chinese medicine to form unique local advantages. At the same time, it keeps up with international research hotspots and supplements scientific research on digital health, mental health, multiple chronic diseases, etc.