To explore the association between HIV testing frequency and pre - / post-exposure prophylaxis (PrEP/PEP) use among individuals at risk of HIV.
Utilizing a follow-up cohort of men who have sex with men (MSM) conducted in five cities (Nanning, Liuzhou, Guilin, Yulin, and Beihai) in Guangxi Province, China, we employed a group-based trajectory model (GBTM) to analyze the developmental trajectories of HIV testing frequency among MSM. Furthermore, we conducted logistic regression analysis to examine the factors associated with different trajectory groups of HIV testing frequency and their relationship with the utilization of PrEP/PEP before and after HIV exposure.
The analysis included a total of 327 MSM participants, with an average age of 27.722±8.137 years. Based on evaluation criteria such as the Bayesian information criterion, GBTM identified three trajectory groups of HIV testing frequency: low-frequency group (73.87%), medium-frequency group (19.75%), and high-frequency group (6.37%). Comparing to the low-frequency group, MSM in the high-frequency group exhibited higher utilization rates of PrEP (9.49% vs. 55.56%) (χ2=32.02, P<0.001) and PEP (17.39% vs. 44.44%) (χ2=8.19, P<0.017). After controlling for relevant confounding factors, the low-frequency group and medium-frequency group showed of the used PrEP by OR=0.153 (95%CI:0.047-0.501, P=0.002) and OR=0.251 (95%CI:0.070-0.907, P=0.035), respectively, compared to the high-frequency group. Furthermore, regarding the frequency of HIV self-testing in the past year, as HIV testing frequency decreased, there was an increase in the frequency of HIV self-testing in the past year (low-frequency group OR=5.664, 95%CI:1.313-24.428, P=0.020) (medium-frequency group OR=5.087. 95%CI:1.082-23.926, P=0.039).
MSM who engage in higher-risk sexual behaviors are more likely to undergo regular and frequent HIV testing, and they are more proactive in using PrEP/PEP for HIV prevention. Compared with MSM with higher frequency of regular HIV testing, MSM with lower frequency of HIV testing showed higher rates of self-testing.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |