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Trajectories of HIV testing frequency and its association with pre-/post-exposure prophylaxis use among men who have sex with men, Guangxi, China
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Yin-xia LIANG1, Hong-bin PENG2, Xia LUO2, Jin-li MO1, Wei-yi TIAN2, Min WANG1, Yun ZHANG2, Ping CEN3, 4, Chuan-yi NING2, 5
Modern Preventive Medicine | 2024, 51(14) : 2634 - 2641
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Modern Preventive Medicine | 2024, 51(14): 2634-2641
Disease Control and Prevention
Trajectories of HIV testing frequency and its association with pre-/post-exposure prophylaxis use among men who have sex with men, Guangxi, China
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Yin-xia LIANG1, Hong-bin PENG2, Xia LUO2, Jin-li MO1, Wei-yi TIAN2, Min WANG1, Yun ZHANG2, Ping CEN3, 4, Chuan-yi NING2, 5
Affiliations
  • The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530007, China
Published: 2024-07-25 doi: 10.20043/j.cnki.MPM.202404106
Outline
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Objective

To explore the association between HIV testing frequency and pre - / post-exposure prophylaxis (PrEP/PEP) use among individuals at risk of HIV.

Methods

Utilizing a follow-up cohort of men who have sex with men (MSM) conducted in five cities (Nanning, Liuzhou, Guilin, Yulin, and Beihai) in Guangxi Province, China, we employed a group-based trajectory model (GBTM) to analyze the developmental trajectories of HIV testing frequency among MSM. Furthermore, we conducted logistic regression analysis to examine the factors associated with different trajectory groups of HIV testing frequency and their relationship with the utilization of PrEP/PEP before and after HIV exposure.

Results

The analysis included a total of 327 MSM participants, with an average age of 27.722±8.137 years. Based on evaluation criteria such as the Bayesian information criterion, GBTM identified three trajectory groups of HIV testing frequency: low-frequency group (73.87%), medium-frequency group (19.75%), and high-frequency group (6.37%). Comparing to the low-frequency group, MSM in the high-frequency group exhibited higher utilization rates of PrEP (9.49% vs. 55.56%) (χ2=32.02, P<0.001) and PEP (17.39% vs. 44.44%) (χ2=8.19, P<0.017). After controlling for relevant confounding factors, the low-frequency group and medium-frequency group showed of the used PrEP by OR=0.153 (95%CI:0.047-0.501, P=0.002) and OR=0.251 (95%CI:0.070-0.907, P=0.035), respectively, compared to the high-frequency group. Furthermore, regarding the frequency of HIV self-testing in the past year, as HIV testing frequency decreased, there was an increase in the frequency of HIV self-testing in the past year (low-frequency group OR=5.664, 95%CI:1.313-24.428, P=0.020) (medium-frequency group OR=5.087. 95%CI:1.082-23.926, P=0.039).

Conclusion

MSM who engage in higher-risk sexual behaviors are more likely to undergo regular and frequent HIV testing, and they are more proactive in using PrEP/PEP for HIV prevention. Compared with MSM with higher frequency of regular HIV testing, MSM with lower frequency of HIV testing showed higher rates of self-testing.

HIV testing  /  Men who have sex with men  /  HIV Pre-/post-exposure prophylaxis  /  Group-based trajectory model
Yin-xia LIANG, Hong-bin PENG, Xia LUO, Jin-li MO, Wei-yi TIAN, Min WANG, Yun ZHANG, Ping CEN, Chuan-yi NING. Trajectories of HIV testing frequency and its association with pre-/post-exposure prophylaxis use among men who have sex with men, Guangxi, China[J]. Modern Preventive Medicine, 2024 , 51 (14) : 2634 -2641 . DOI: 10.20043/j.cnki.MPM.202404106
Year 2024 volume 51 Issue 14
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doi: 10.20043/j.cnki.MPM.202404106
  • Receive Date:2024-04-07
  • Online Date:2026-03-18
  • Published:2024-07-25
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  • Received:2024-04-07
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    The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530007, China
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表12种不同金属材料的力学参数

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Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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