Objective Based on UHPLC-Orbitrap HRMS, combined withQuECHERS pretreatment technology, a rapid screening detection method wasestablished to simultaneously screen and confirm 14 categories of 140illegally added drugs in herbal tea. Methods The sample was extractedwith methanol, and purified by dispersed solid phase extraction withsodium acetate and anhydrous magnesium sulfate, neutral alumina andoctadecyl bonded silica gel, separated by a chromatographic columnWaters BEH ${\mathrm{C}}_{18}\left({{2.1}\mathrm{\;{mm}}\times {50}\mathrm{\;{mm}},{1.7\mu}\mathrm{m}}\right)$ , and gradient eluted by two independentmobile phase systems: ${0.2}\%$ formicacid water $\left({V/V}\right)$ solution $\sim {0.2}\%$ formic acidacetonitrile $\left({V/V}\right)$ solution and water-acetonitrile, Full $\mathrm{{MS}}/{\mathrm{{dd}- {MS}}}^{2}$ mode was used to collect data, the standard curve was prepared byextracting solution from blank sample and the external standard methodwas used for quantification. Results The linear relationship of 20representative quality control compounds was good $\left({{r}^{2}> {0.995}}\right)$ from5.0 to ${200}\mathrm{{ng}}/\mathrm{{mL}}$ massconcentration, the average recovery rateat the three levels of low,medium and high is between 83.1% and 107.3%, the relative standarddeviation is less than 15.6% and detection low limit is between ${0.2}\mathrm{{mg}}/\mathrm{{kg}}$ and ${1.0}\mathrm{{mg}}/\mathrm{{kg}}$ .165 herbal tea samples on the market were determined and results showedthat twelve samples were positive, the positive components werechlorpheniramine, acetaminophen, diclofenac sodium, ibuprofen,dexamethasone acetate, erythromycin and florfenicol. Conclusion Themethod has the advantages of simple operation, high sensitivity andhigh-throughput screening. Is suitable for the detection of illegallyadded drugs in herbal tea and other health foods.

Objective A 4-mercaptobenzoic acid/polypeptide-modifiedgold nanoparticle modified surface enhanced Raman spectroscopy (SERS)sensor was developed for rapid detection ofAg ${}^{+ }$ in water. Methods $\;\mathrm{A}{\mathrm{{Ag}}}^{+ }$ surfaceenhanced Raman spectroscopy sensor was constructed by combining aspecificAg ${}^{+ }$ peptiderecognition sequence (RFPRGGDD) with 4-mercaptobenzoic acid, and datawas read using a portable Raman spectrometer. Results In theconcentration range of ${10}\sim {850}\mathrm{{nmol}}/\mathrm{L}$ ,the linear relationship was good, the correlation coefficient $\left({r}^{2}\right)$ was 0.98345, thelimit of detection was ${36}\mathrm{{pmol}}/\mathrm{L}$ , thestandard recoveries were ${95.28}\%\sim {102.9}\%$ , and therelative standard deviations were 0.79%~3.73%. Conclusion The method has high response speed, good selectivity and low detection limit, and is suitable for rapiddetection of Ag+ in water.

Objective To establish an optimal method for thedetermination of available copper, iron, manganese and zinc in soil inSanpu. Methods AB-DTPA leaching and inductively coupled plasmaspectrometry were used to determine the available $\mathrm{{Cu}},\mathrm{{Fe}},\mathrm{{Mn}}$ and $\mathrm{{Zn}}$ in soilsimultaneously. Results The detection limit and precision met theanalysis requirements, and the high accuracy of copper, iron andmanganese were in the concentration range of ${0.50}\sim {100}\mathrm{{mg}}/\mathrm{L}$ ,and zinc was in the concentration range of ${0.25}\sim {10.0}\mathrm{{mg}}/\mathrm{L}$ .The linear relationship was good, and the correlation coefficients wereall above 0.999 . The detection range of the method was in the range of ${0.06}\sim {0.69}\mathrm{{mg}}/\mathrm{{kg}}$ ,and the blank test results were stable. The precision of the methods wasless than 5.0%, and the parallel differences of the samples were allwithin the qualified range. The available iron, manganese and copper,zinc in the sample are different by one to two orders of magnitude, andthe determination can still obtain accurate results. Conclusion Thedetection limit and precision of this method meet the requirements ofanalysis, and the accuracy is high, which is suitable for the detectionof available copper, iron, manganese and zinc in soil.

Objective To optimize the conditions for the determinationof total $\alpha$ and total $\beta$ radioactivity in drinking water andimprove the accuracy of the experiment. Methods On the basis ofmeasuring the residue content in drinking water, the total $\alpha$ and $\beta$ radioactivity values in drinkingwater were determined by improving evaporation and concentration processand optimizing reagent conditions. Results In this study, the amount ofresidue, $\alpha$ and $\beta$ radioactivity increased, and thetest time was reduced compared with the traditional method. Conclusion The method significantly improves the accuracy of results and testingefficiency and can be further optimized. It provides certain researchsignificance in the quality control of laboratory measurements.

Objective To study and improve medical equipment fault diagnosis techniques by utilizing system state detection methods to quickly and accurately diagnose faults in medical equipment without schematics, thereby enhancing the efficiency and accuracy of equipment maintenance. Methods This study employed the system state detection method, using online testers and digital oscilloscopes to establish a system state database for the equipment. The study involved 20 common medical devices from a hospital, including blood oxygen monitors and laminar flow fan frequency converters. When equipment failures occurred, traditional fault localization methods were first used to narrow the fault range to the board level. Subsequently, online testers and digital oscilloscopes were used for component comparison testing, combined with previous successful cases for fault diagnosis. Results Among the 20 medical devices, 18 were successfully diagnosed and repaired, achieving a fault diagnosis accuracy rate of 90%. Specific cases included successfully eliminating ADC chip faults in the PM9000 monitor's blood oxygen board and E2PROM faults in the laminar flow fan frequency converter. By establishing a system state database and case database, the efficiency of equipment fault diagnosis was significantly improved, with the average diagnosis time reduced by 30%. Conclusion System state detection can effectively enhance the accuracy of medical equipment fault diagnosis and should be further promoted to optimize maintenance management.

Objective To investigate the disintegration and dissolutionproperties of alprogesterone as a feed additive under differentenvironmental conditions, and to develop a suitable tablet for pig farmfeeding. Methods The prescription was screened by 3-factor and 3-levelorthogonal test, and the disintegration time, dissolution and appearancequality of the tablets were tested. Results The disintegration time ofthe optimized allyl gestrel was $7\sim {15}\mathrm{\;{min}}$ , which was better than $2 \sim 5\mathrm{\;{min}}$ of conventionaltablets. Conclusion The optimized dissolution and content of allylgestrel meet the standard, which is convenient for sows to consume andcan meet the feeding needs of pig farms.

Objective To investigate the agglomeration of particulate matter at the air-leaf interface and provide guidance for the prevention and control of particulate matter and greening planning. Methods In this study, the effects of temperature and wind speed on plant coagulation effect were studied by using a self-developed system of coagulation effect based on aerosol smoke box, and the coagulation effect of particulate matter in the leaves of 10 common green tree species in Shanghai was measured. Results The coagulation effect of plant leaves is affected by external conditions, which increases and then decreases with the increase of temperature and is positively correlated with wind speed; among different plants, the coagulation effect of coniferous species is greater than that of broad-leaved species, small-leaved species is greater than that of large-leaved species. Conclusion The results of the study can provide scientific basis for the key prevention and control management of haze, the plant configuration mode of green space community and the selection of urban greening tree species.

Objective To improve the detection method of bulk densityof powder materials, in order to improve the accuracy and efficiency ofthe detection results of cement. Methods Through the improvement ofauxiliary metal rod rotation technology at the pipe to loosen thematerial and make it fall naturally, the detection data before and afterthe improvement of cement volume density detection technology werecompared to find a more environmentally friendly, faster and accuratetest method. Results The improved test data did not fluctuate due to theequipment displacement, and the cement bulk density remained at ${1.03}\mathrm{\;g}/{\mathrm{{cm}}}^{3}$ inthe loose state, the whole test process took a short time ( ${1.5}\mathrm{\;{min}}$ ), there was no dustin the test process, and the test results did not exceed the errorrange, all of which were better than the measured data before theimprovement. Conclusion The improved test method can improve theaccuracy and precision of cement performance test more scientifically,and can make the test results closer to the real value, which isfeasible, has certain social and economic value, and is worthpopularizing.

With the continuous increase in the number and scale of university laboratories, traditional management models face many drawbacks such as low efficiency, resource waste, and safety hazards. In order to address these drawbacks, artificial intelligence technology has gradually been introduced into the intelligent management of university laboratories. This article aims to explore the application of artificial intelligence in the management of university laboratories, analyze its role in resource optimization, security management, equipment maintenance, and data analysis, and promote the better application of artificial intelligence in the intelligent management of university laboratories.

In modern society, food and drug safety is a major issue related to public health and social stability. With the progress of science and technology, the application of information technology in food and drug inspection and testing has become the key to improve the efficiency and accuracy of testing. This paper aims to discuss the specific application and role of information technology in food and drug inspection and testing. From automated detection to advanced data analysis, from remote monitoring to the application of blockchain technology, information technology is gradually changing the face of food and drug inspection and testing, providing strong technical support to ensure product quality and public health and safety. Through comprehensive analysis of these technologies, this article aims to provide reference and guidance for the research and practice of informationization in the field of food and drug testing.

Objective This study aims to establish an efficient andaccurate method for the determination of zinc content in mineral samplesbased on the flame absorption method of atomic absorptionspectrophotometer, in order to meet the growing demand for metal elementdetection in various fields. Methods The zinc content was determined byatomic absorption spectrophotometer, combined with pretreatment samples,experimental procedure, optimization of instrument measurementconditions and establishment of standard curve. Results The establishedmethod has high precision and accuracy, the recovery rate is99.1%~99.9%, and the correlation coefficient is 0.9998 . The detectionlimit of the method was ${0.1}\mathrm{{\mug}}/\mathrm{{mL}}$ , indicating that the method had goodquantitative analysis ability. Conclusion The method has not only highsensitivity and selectivity, but also simple operation and reliableresults, which is of great significance for environmental protection andoptimal utilization of resources.

Objective To analyze and discuss the influence of qualitycontrol on clinical laboratory results under the management of clinicallaboratory control, and to clarify the effective value of qualitycontrol in clinical laboratory. Methods A total of 80 patients who werecompletely registered in our hospital from January to August, 2023 andreceived medical examination were selected for a controlled study. Thepatients in the control group were treated with routine qualitymanagement methods, while the patients in the research group weretreated with quality control methods. Compare the qualified rate,satisfaction and examination results of nursing staff in the two groups,and collect the reasons for the unqualified examination results andevaluate them. Results Compared with the qualified rate of patients, theoverall qualified rate of the study group was ${97.5}\%$ , which was significantly higherthan that of the control group (85%), with statistical significance $\left({P <{0.05}}\right)$ .Compared with the patients’ satisfaction degree, the overallsatisfaction degree of the study group was 97.5%, which wassignificantly higher than that of the control group (72.5%), withsignificant difference (P<0.05). Compared with the examinationresults of nurses in departments, the patient education ability, samplecollection ability and sample processing ability of nurses in the studygroup were $\left({{89.91}\pm {4.56}}\right)$ points, $\left({{89.52}\pm {5.11}}\right)$ pointsand $\left({{88.88}\pm {4.44}}\right)$ points,which were significantly higher than those in the control group, withsignificant differences $\left({P<{0.05}}\right)$ . Conclusion Doing a good job in qualitycontrol and optimizing clinical medical examination can significantlyimprove the quality of hospital clinical examination, improve patients’satisfaction, improve clinical nurses’ cognition of clinical medicalexamination and enhance their clinical practice ability, which has highclinical application value and can be widely popularized.

With the rapid development of China's automobile industry, vehicle engineering talents are in great demand. College vehicle engineering laboratory is an important place for vehicle engineering specialty to carry out basic and critical education and teaching work, so it is increasingly important to improve the construction level of vehicle engineering specialty laboratory. At present, equipment maintenance and management measures are not in place in vehicle engineering laboratories, which leads to high failure rate and low utilization rate of laboratory equipment. Based on the analysis of equipment failure in the laboratory of vehicle engineering specialty, this paper puts forward the strategy of periodic maintenance, equipment maintenance and management measures such as preventive maintenance strategies, building equipment management systems, and improving use specifications provide ideas for further improving the construction level of vehicle engineering professional laboratories.

University laboratory is an important place for scientific research, and the safety management of laboratory is directly related to the life safety of teachers and students, and will affect the smooth progress of scientific research. However, the traditional management mode has a certain lag, especially in the current situation of more and more types of various tests and more complex, it is very important to actively adopt efficient management to strengthen the management of university laboratory. Capability maturity model is an advanced management concept, which has been gradually introduced into the management of many organizational structures in recent years, and gradually introduced into the management of university laboratories. Therefore, this paper makes an in-depth analysis of university laboratory security management under the guidance of capability maturity model.

With the rapid development of the discipline construction and scientific research level in universities, the safety management of biological laboratories in universities is facing increasingly severe challenges. This paper takes the biological laboratory of a foreign university as the research object, and draws valuable experience from the biological laboratory safety management practice of the university through the analysis of the laboratory safety management organization and management system, which can provide useful reference for the safety construction, network management and training system of biological laboratories in China. It is helpful to improve the standardization and effectiveness of biological laboratory safety management.

With the development of higher education and the improvement of scientific research level, university laboratories have become an important place for cultivating talents and conducting scientific research. The cross-integration of discipline development puts forward higher requirements for the construction of laboratory safety education system. Therefore, it is very important to establish a perfect laboratory safety education system in colleges and universities. This paper focuses on the construction and practice of laboratory safety education system in colleges and universities, and constructs a standardized safety education system from eight elements: educational objectives, educational models, educational objects, teaching staff, educational content, educational methods, assessment and conditions guarantee. Through the system construction and practice, it aims to improve the safety awareness and coping ability of laboratory personnel, reduce the incidence of safety accidents and provide a strong guarantee for the safe operation of university laboratories.

Objective To explore the implementation effect of thequality improvement model based on the backtracking system in thehospital inspection department. Methods 102 patients who implemented theconventional quality management model in the inspection department ofthe hospital from September 2021 to September 2022 were selected as thecontrol group, and 102 patients who implemented the quality improvementmodel based on the quality management system in the inspectiondepartment of the hospital from October 2022 to October 2023 wereselected as the observation group. The two groups of inspectiondepartment personnel (24) are all members of the same group.Compare theassessment and scoring of the two groups of inspection departmentpersonnel, the quality of the inspection and the patient satisfaction. Results Compared with the control group, the data obtained showed thatthe theoretical knowledge, operating skills, service quality, equipmentmaintenance and maintenance, equipment use process, and equipmentmanagement ability scores of the inspection department personnel in theobservation group were higher, and the differences were meaningful froma statistical point of view $\left({P<{0.05}}\right)$ ; compared with the control group, thequality inspection effect, safety management, ward management andworking environment scores of the inspection department personnel in theobservation group were higher, and the differences were meaningful froma statistical point of view $\left({P<{0.05}}\right)$ ; Compared with the control group, the dataobtained showed that the patient satisfaction of the observation groupwas higher, and the differences were meaningful from a statistical pointof view $\left({P<{0.05}}\right)$ ; Compared with the control group, thepatient satisfaction of the observation group was higher, and thedifferences were meaningful from a statistical point of view $\left({P <{0.05}}\right)$ ; The dataobtained compared with the control group, the patient satisfaction ofthe observation group was higher, and THE differences were meaningfulfrom a statistical point of view $\left({P<{0.05}}\right)$ . Conclusion The application of the qualityimprovement model based on the backtracking system to the hospitalinspection department can improve the assessment and scoring of itsinspectors and the quality of inspections, and the patient satisfactionis higher and the implementation effect is better.

In order to improve the comprehensive service capabilities of medical device inspection and testing laboratories, the inspection and testing business activities are empowered by digital means, and complete the digitization of the entire lifecycle of laboratory business. This article proposed a construction idea and design plan for the digitization of provincial medical device inspection institutions laboratories, designed the design principles, technical routes, and architecture of digital laboratories, constructed application scenarios for business and digital capabilities, strengthened the quality system of inspection and testing business, and utilized risk monitoring analysis and application of daily commissioning, supervision sampling, registration inspection, rapid evaluation, and defect/warning/recall to better serve supervision and enterprises.

With the rapid development of information technology and the deepening implementation of digital transformation, digital management has been applied to various fields and industries. To meet the quality requirements regardless of improvement, third-party inspection and testing institutions are constantly trying innovative digital management methods to improve the efficiency and accuracy of their equipment management and monitoring. This paper deeply discussed the current situation and existing problems of equipment management in third-party inspection and testing institutions, and proposed feasibility analysis and application scenarios for the intelligent management and application of equipment numbers in third-party inspection and testing institutions. This paper improved the efficiency of equipment management by automating intelligent equipment and implementing data monitoring, and integrated and analyzed equipment data by using data intelligent management to provide data support for accurate decision-making.

Objective To investigate the effect of laboratoryinformation management system applied in the quality management oflaboratory department and its impact on the accuracy of specimen testreport. Methods The 1876 specimens that were tested in the laboratorydepartment of our hospital from January 2022 to December 2023 wereincluded in the study, and were divided into two teams according to thedifferent management modes chosen for different time periods; theroutine management was implemented in the laboratory department fromJanuary 2022 to December 2022 ( $n={938}$ , included in the routine team), and the routinemanagement measures were carried out on the basis of the routinemanagement measures in the laboratory department from January 2023 toDecember 2023 ( $n ={938}$ , includedin the surveyteam), to observe the impact of adverse events, test reportsituation and management effect under different management modes. Results Comparing the incidence of adverse events (mislabeling, specimenloss, test failure) between the two teams, the surveyteam (1.81%) waslower $\left({{\chi }^{2}= {7.627}, P<{0.05}}\right)$ ; comparing the specimen test reports betweenthe two teams, the surveyteam had a higher rate of return of criticalvalues, qualified rate of test returns, accurate rate of test reports,and timely rate of critical value reports $\left({P <{0.05}}\right)$ ; Comparisonof the management effect scores of the two teams under differentmanagement modes, the management effect scores of the inspectionpersonnel during the management period were higher in the surveyteam(P<0.05).

The large-scale instrument sharing platform in universities is the core resource for sharing scientific and technological resources. It not only provides strong support for teaching and research in various universities, but also offers technical support to relevant enterprises and other social units. After analyzing the current large-scale instrument sharing platforms in universities, it was found that there are problems in the service process. Based on the development of service plans, the construction of experimental teams, cross institutional cooperation mechanisms, and service quality evaluation and monitoring mechanisms, a “one-stop" service system guided by "demand" was proposed to optimize the entire service process, promote the improvement of sharing benefits, and form a closed-loop management.

Information management is an inevitable trend in the management of monitoring laboratories, more and more environmental monitoring institutions are starting to build LIMS, promote the development of environmental monitoring towards automation, standardization, and effectiveness. Analyses the current status of LIMS construction in various industries in China, taking Chongqing ecological environment monitoring business management system as an example, propose the design of system functional, summarize the experience of successful system implementation, provide references measures for vertical management of environmental monitoring institutions.

Spinning disk confocal microscope isa widely used optical instrument. This article take the live cell spinning disk confocal system of the large-scale instrument sharing platform of Wenzhou Medical University as an example, to introduce the basic technical principles and open sharing status of this instrument. Based on actual operating conditions, thisarticle explores the content and methods of training to further improve the effectiveness and feasibility of the training mode, providing a reference for relevant technical personnel.

This paper discusses the importance and practical path of cultivating innovative talents by using the open sharing platform of large instruments and equipment in testing laboratory. In view of the challenges such as resource limitation, lack of professional training and defect of scientific research environment in the cultivation of innovative talents for large instruments and equipment, the paper puts forward some solutions such as building operation and maintenance team, developing innovative training projects and establishing skill training system. It is emphasized that these measures can stimulate students' innovative thinking and practical ability, and realize the cultivation of innovative talents based on the open sharing platform of large-scale instruments and equipment for testing.

In the context of increasingly serious global diseases and health problems, the importance of biosafety concept has become increasingly prominent. As a country with biological diversity, China faces more serious public health risks. Laboratory safety, as an important link to strengthen biosafety protection, especially for the safety of pathogenic microorganism laboratories, is an important link to reduce the exposure and spread of dangerous goods, and ensure public health and life safety. Scientific laboratory safety management is of great importance. In order to improve the management level of pathogenic microbiology laboratory, the application of digital technology and the construction of information laboratory record management platform are of great application significance, which can effectively realize an efficient, integrated and standardized laboratory management mechanism, and provide support for the optimization and construction of public facilities such as pathogenic microbiology laboratory. This study will mainly explore the optimization path of the construction of the pathogenic microbiology laboratory record management platform, combined with the development requirements of the industry, social needs, etc., to build an efficient management system and improve the quality of laboratory safety management.

Objective To observe and analyze the clinical effect of drychemistry and urine sediment. Methods This study selected 150 patientsin our hospital from January 2022 to June 2022, divided into threegroups, experimental group of 50 patients with routine urine test usingdry chemical method, observation group of 50 patients with urine routinetest, the control group of dry chemistry method and urine sediment, andthe detection of the index of patients in urine routine test. Results The comparison of each index in the experimental group and theobservation group with routine urine test was less than that of urineroutine test in the control group using the combined method of drychemistry and urine sediment; the misdiagnosis rate in the experimentalgroup with a routine urine test using dry chemistry was $8\%$ , the missed diagnosis rate was 14%,the total error rate was 22%; the misdiagnosis rate in the observationgroup using the routine urine test was 10%, the missed diagnosis ratewas ${18}\%$ , the total error ratewas ${28}\%$ ; the misdiagnosis rateof the control group with routine urine test using combined drychemistry and urine sediment was 2%, the missed diagnosis rate was 2%,the total error rate was 4%, the total error rate of the experimentalgroups with routine dry chemistry urine testing and the observationgroups with routine urine sediment testing was greater than that of thecontrol group with routine urine testing using combined dry chemistryand urine sediment, the statistical significant difference wassignificant $\left({P<{0.05}}\right)$ . Conclusion After the active cooperation ofrelevant researchers and patients, the clinical effect observation ofurine routine test shows that the combination of dry chemistry and urinesediment is the best clinical effect.

Objective To explore and analyze the value of seruminflammatory indexes, D-dimer (D-D) and bone biochemical indexes inwound healing of patients with fractures. Methods The clinical data of92 patients with fracturesin the hospitalwere retrospectively analyzedfrom March 2021 to February 2023. The above patients were divided intodelayed group $(n ={47}$ , delayedfracture healing) and normal group $(n={47}$ , normal fracture healing). The levels of high-sensitivityC-reactive protein (hs-CRP), procalcitonin (PCT), D-D and bonebiochemical indexes (bone gla protein (BGP), type I procollagen aminoterminal peptide (PINP), type I collagen cross-linked carboxy terminalpeptide (CTX), bone alkaline phosphatase (BALP) were compared betweengroups. Pearson analysis was used to analyze the correlation between theabove indexes and delayed fracture healing. Receiver operatingcharacteristic curve (ROC) was adopted to evaluate the predictive valueof the above indexeson predicting delayed fracture healing. Results Thelevels of hs-CRP, PCT, D-D and CTX in delayed group were higher thanthose in normal group $\left({P<{0.05}}\right)$ while the levels of BGP, PINP and BALP werelower than those in normal group $\left({P<{0.05}}\right)$ . Serum hs-CRP, PCT, D-D and CTX in patientswith fractures were positively correlated with delayed fracture healing $\left({P <{0.05}}\right)$ , andBGP, PINP and BALP were negatively correlated with delayed fracturehealing $\left({P<{0.05}}\right)$ . Under the ROC curve, the areas under thecurves (AUCs) of hs-CRP, PCT, D-D, CTX, BGP, PINP, and BALP inpredicting delayed fracture healing were 0.693, 0.810, 0.722, 0.763,0.746, 0.868 and 0.839, the sensitivities were 59.57%, ${59.57}\%,{72.34}\%,{59.57}\%,{85.11}\%,{93.62}\%$ and 76.60%, and the specificities were 78.72%,97.87%,65.96%,89.36%,59.57%, 72.34% and 80.85% respectively. Conclusion hs-CRP, PCT, D-D andbone biochemical indexes are closely related to delayed fracture healingin patients with fractures, which should be paid attention to inclinical practice.

Objective This study aims to compare and evaluate theperformance and applicability of two ammonia $\left({\mathrm{{NH}}}_{3}\right)$ detection methods in the field and laboratory. Methods The C16 portable ${\mathrm{{NH}}}_{3}$ gas detectorand GBZ/T 160.29-2004 ammonia Nessler’s reagent spectrophotometricmethod were used to perform 10 repeated measurements of 5 differentconcentrations $\left({{9.3}\sim {148.8}\mathrm{{mg}}/{\mathrm{m}}^{3}}\right)$ of ${\mathrm{{NH}}}_{3}$ standardgases. Results The results showed that the C16 portable detectorexhibited a highly linear relationship $\left({r ={0.9998}}\right)$ in fieldapplications, which was highly correlated with the concentration ofstandard gases; The GBZ/T 160.29-2004 method provides higher precisionmeasurement values in laboratory analysis. The relative standarddeviation and relative error of both methods are less than ±5%,demonstrating good precision and accuracy. The research conclusionindicates that the C16 portable detector is suitable for rapid on-sitedetection and emergency response, while the GBZ/T 160.29-2004 method ismore suitable for laboratory analysis that requires high precision. Conclusion This study provides a scientific basis for selectingappropriate ${\mathrm{{NH}}}_{3}$ detection methods, which is of great significance for improving thequality of environmental monitoring and occupational healthassessment.

Objective To develop a scientific method for identifyingsea sand to differentiate it from river sand. Methods Qualitative andquantitative analysis of sea sand is conducted through its sensorycharacteristics, microscopic features, chemical and physical properties,and volumetric measurement methods. Results The chemical analysis showsthat sea sand is different from river sand with high chloride content(≥0.01%) and high shell content (≥0.1%). The electrical conductivity ofsea sand is significantly higher than that of river sand. In terms ofquantitative analysis, the relative deviation of the sea sand weightcalculation method proposed in this study is ${0.25}\%\sim {0.87}\%$ , which is close tothe allowable error of $\pm {0.3}\%$ of the truck scale. Conclusion The identification method proposed inthis study can quickly and effectively distinguish sea sand, which is ofgreat significance in ensuring the safety of building materials.

Objective To understand the pathogenic spectrum compositionof bacterial diarrhea in Jiangxia District of Wuhan, to explore thevariation and epidemic changes of the main pathogenic bacteria inJiangxia District of Wuhan in recent years, and to provide scientificbasis for the diagnosis and prevention and control of bacterialdiarrhea. Methods 341 specimens of patients with bacterial diarrheasyndrome in Jiangxia District of Wuhan from 2021 to 2023 were collected,and a variety of intestinal pathogenic bacteria were detected, and thedrug resistance of the detected pathogenic bacteria was analyzed. Results The highest detection rate in 2021-2023 was Salmonella,accounting for 42.82%(146/341) of cases detected; next is Vibrio, with adetection rate of ${16.42}\%\left({{56}/{341}}\right)$ ; thethird place is Escherichia coli, with a detection rate of 6.74%(23/341).In the typing results, the most commonly detected strains of Salmonella,Vibrio, and Escherichia coli were Salmonella enterica, Vibrioparahaemolyticus, and pathogenic Escherichia coli, with detection ratesof 14.37%, 13.20%, and 3.52%, respectively. Among the 341 detectedbacteria, the age group of 20~40 had the highest number of detectedbacteria, with 223, accounting for 65.40% of the total; 118 strains weredetected in the age group of 40~60, accounting for 34.60% of the total.There is a statistically significant difference between the two agegroups $\left({{\chi }^{2}= {57.484}, P<{0.001}}\right)$ . Conclusion Salmonella is the main pathogenic bacteria of bacterial diarrhea in Jiangxia District of Wuhan from 2021 to2023.

Objective This study aims to conduct a compatibility testbetween human fibrinogen and inner packaging materials throughaccelerated testing, explore the stability of drugs, determine whetherinner packaging materials have an impact on product quality, and providenecessary information for formulation design, packaging, transportation,and storage. Methods Conduct accelerated testing using 3 batches of testsamples, and place them upright and inverted at a temperature of $\left({{25}\pm 2}\right){}^{\circ }\mathrm{C}$ for6months. During the experimental period, samples were taken at theend of the third and sixth months respectively, and tested according tothe accelerated stability key inspection items (appearance, vacuumdegree, reconstitution time, visible foreign matter, osmotic pressuremolar concentration, stability test, moisture, $\mathrm{{pH}}$ value, purity, total amountof human fibrinogen, coagulation activity, arginine hydrochloride,citrate ions, sterility test), and compared with the results of Month 0. Results After being stored at ${\left({25}\pm 2\right)}^{\circ }\mathrm{C}$ for6months, the relevant migration products met the requirements, andthere were no significant changes in the activity indicators. Otherbiochemical detection indicators met the requirements of the ChinesePharmacopoeia (2020 edition, Part III), and there were no significantdifferences in the changes of the detection results of each indicator. Conclusion The selected packaging system has no adverse effects on thequality of human fibrinogen, and the drug quality in the selectedpackaging container is stable and controllable, which can maintain itssafety and effectiveness in use. The inner packaging material has nosignificant impact on the quality of the formulation and has goodcompatibility.

Objective To supervise and evaluate the rapid testing laboratory of edible agricultural products, and to check the implementation of local rapid testing. Methods On the basis of the relevant evaluation rules of Guangdong administration for market regulation, combined with the relevant requirements of the government's rapid inspection laboratory operation and management, a comprehensive evaluation of the rapid inspection laboratory was conducted from the aspects of laboratory site, rapid inspection system establishment, completion situation, sampling situation, original records, follow-up treatment, quick inspection products and equipment management. Results The supervision and evaluation of 12 government rapid inspection laboratories for edible agricultural products was carried out, and the comprehensive scores were all above 89 points. Each government rapid inspection laboratory assessed 6 blind samples, only E government rapid inspection laboratory blind sample assessment accuracy rate did not reach 100%. The results of supervision and evaluation were satisfactory. Conclusion The rapid inspection laboratory of local edible agricultural products has achieved certain results in giving play to the 'firewall' of rapid inspection and screening, but there are still some problems and risk points. It is suggested to start with personnel training, original records, rapid inspection products and equipment management, rapid inspection quality control, supervision and assessment, so as to promote the continuous improvement of the detection ability of the rapid inspection laboratory.

Objective To determine the content of inorganic arsenic inshellfish and aquatic products by high performance liquidchromatography-inductively coupled plasma mass spectrometry, and toevaluate the food safety according to the content level of inorganicarsenic. Methods Four kinds of shellfish products were randomlypurchased from local markets and extracted by soaking in acid solution.After separation and filtration, the content of inorganic arsenic in theextracted solution was determined. Results The average inorganic arseniccontent of the 4 kinds of shellfish products were 0.067 ~0.140 mg/kg forPaphia undulata, 0.120 ~0.470 mg/kg for clam Philippines, 0.061 ~0.140mg/kg for clam white, and ${0.056}\sim {0.190}\mathrm{{mg}}/\mathrm{{kg}}$ for Sinonovacula constricta, respectively. The highest content ofinorganic arsenic was found in Philippinarum clam. Conclusion Thecontent of inorganic arsenic in shellfish products sold in Foshan Cityin 2023 does not exceed the limit value of ${0.5}\mathrm{{mg}}/\mathrm{{kg}}$ ofChina’s national food safety standard. Common shellfish aquatic productsare generally safe to eat. However, it is still necessary to be cautiousabout eating high-risk shellfish products and pay attention to thoroughcooking and processing. At the same time, it is necessary to strengthenthe awareness of food safety, strengthen the supervision and managementof such aquatic products, and carry out food safety knowledge publicityand health education.

Objective To study the bacteriological test method ofsputum samples and the effect of clinical infection. Methods A total of240 samples were collected from May 2019 to May 2020. After the twogroups, the conventional test samples were collected by sputum culture,and the test sample was improved by bacteriology and sputum culture,comparing the sample quality and test results. Results According to thecomparison analysis, the sample quality, disease detection rate andstrain positive rate of the study group were ideal, and the group weredominant $\left({P<{0.05}}\right)$ . Conclusion The implementation ofbacteriological test of sputum specimens can accurately detect patients,and the proportion of clinical infection is ideal, so it has goodimplementation effect and clinical application value.

Objective Goal by verifying the performance indicators of16 items such as alanine aminotransferase (ALT), the performance of thedetection system of BS-2800M, a fully automatic biochemical analyzerproduced by Mindray manufacturer, which was newly put into use in thislaboratory was evaluated, so as to improve the work quality of thelaboratory and ensure the accuracy and reliability of the test results. Methods According to the accuracy, precision, linear range and referenceinterval of the test items, the performance of 16 test items such asalanine aminotransferase (ALT) was evaluated. No unacceptableperformance was found in the evaluation process, indicating that theanalytical performance of the test method was accepted and met therequirements of clinical specimen detection. The entire validationprocess is based on the Requirements of the Guidelines for theAccreditation of Quality and Competence of Medical Laboratories in theField of Clinical Chemistry Examination, referring to the requirementsof CLSI EP15-A3, EP6, C28-A2 and EP15-A23 documents. Results Therelative bias of 16 items was $<1/2$ total allowable error (TEa). The coefficient of variation(CV) in precision batch was $<1/4$ tea, the total CV was $<1/3$ tea, the b values of 16 items were in the range of ${1.00}\pm {0.03}$ , and ${r}^{2}$ was $\geq {0.95}$ . The maximum dilution andclinical reportable range were verified and met the requirements. Conclusion The accuracy, precision, linearity and clinical reportablerange of the 16 tested items meet the requirements of quality objectivesand can be used for clinical detection.

Surface water is an indispensable and important resource in human life and production. However, the existence of trace metal elements in surface water poses a potential threat to the safety of water quality. Therefore, it is important to perform accurate and rapid monitoring of trace metal elements in surface water. This article reviews the application of ICP-MS in monitoring trace metal elements in surface water, analyzes the challenges and countermeasures in its application process, and provides accurate data reference for the comprehensive development of surface water protection work. Reference for the comprehensive development of surface water protection work.

Objective To understand the water quality and health status of swimming pools in Banan District of Chongqing, and to provide scientific basis for further strengthening the health management of swimming places, so as to ensure the health of swimming enthusiasts. Methods The total bacterial count and coliform microbial index of swimming pool water in Banan District of Chongqing were monitored. Results A total of 384 swimming pool water samples were monitored in Banan District of Chongqing from 2018 to 2022, and the overall qualified rate was ${97.12}\%$, the lowest qualified rate was ${90.70}\%$ in 2020, and there was no significant difference in 5-year qualified rate $\left({{\chi }^{2}= {6.395}, P >{0.05}}\right)$. There was no significant difference in the qualified rate of microbial detection in swimming pool water between different seasons $\left({{\chi }^{2}= {4.899}}\right.$, $P >{0.05})$. There was significant difference in the qualified rate of microorganism monitoring in swimming pool water of different types of swimming pool venues $\left({{\chi }^{2}= {17.361}, P <{0.01}}\right)$. Conclusion The microbial detection of swimming pool water in Banan District of Chongqing from 2018 to 2022 is generally good, but there are still some unqualified samples. It is necessary to strengthen the supervision and management of microorganism detection in swimming pool water and relevant technical guidance.

Objective To investigate the effects of enrofloxacin andciprofloxacin residues in hot processed shrimp and to provide referencefor dietary risk assessment. Methods The shrimp (Penaeus indicus) afterdrug administration was selected as raw material, and a detection methodbased on RP-HPLC-FLD was established. The shrimp was processed by twohot processing methods: boiling and drying. The effects of water-shrimpratio (proportion of water to shrimp), boil holding time, dryingtemperature and drying time on residual concentrations of enrofloxacinand ciprofloxacin in shrimp were evaluated. Results During the boilingprocess, the residual concentrations of enrofloxacin and ciprofloxacinin shrimp decreased with the increase of water-to-shrimp ratio andboiling retention time, and the residual concentrations reached theminimum when the water-to-shrimp ratio was 5 . Under this condition, theeffect on the residual concentrations was significantly reduced afterthe boiling retention time reached ${20}\mathrm{\;{min}}$ . During the dryingprocess, the residual concentrations of enrofloxacin and ciprofloxacinincreased with increasing drying temperature and remained basicallyunchanged between 150 and ${180}^{\circ }\mathrm{C}$ . When thedrying temperature was set at ${150}^{\circ }\mathrm{C}$ , the residualconcentration increased with the increase of drying time and remainedbasically unchanged between 5 and 8 min. Studies have shown that boilingcan significantly reduce the residual concentrations of enrofloxacin andciprofloxacin in shrimp, while drying can cause the residualconcentrations to increase on the basis of boiling. The overallprocessing factor of enrofloxacin and ciprofloxacin was less than 1 ,indicating that the residual concentrations of enrofloxacin andciprofloxacin in dried shrimp were lower than those in raw shrimp. Conclusion The study in this paper can help processing enterprises orquality supervision departments to effectively evaluate the impact ofantibiotic residues in hot processing shrimp, and put forward relevantsuggestions on food safety.

The quality of urban sewage discharge affects the protection of urban water resources, ecological environment and so on, and has an impact on urban economic development and civilization construction. Therefore, it is very important to do a good job in water quality monitoring and management of drainage pipe network. This paper briefly describes the importance of water quality monitoring and water quality management, analyzes the factors that affect the quality of water quality monitoring, including human causes and monitoring equipment, and puts forward measures to improve the quality of water quality monitoring results. Finally, it puts forward measures such as building an information management system of drainage pipe network and perfecting the water quality monitoring management system to ensure the quality of urban sewage discharge.

In order to build a comprehensive and in-depth university laboratory safety management system and systematically eliminate laboratory safety hazards, this article takes 259 core literature on university laboratory safety management systems collected from "China National Knowledge Infrastructure" from 2008 to 2024 as the basic data, and uses Cite Space software to visualize the research authors, research institutions, keywords, and other aspects, further analyzing the research status and development trends. The results indicate that the number of publications in this field has been increasing year by year, but there is relatively little interaction among researchers, and research institutions are relatively independent with unclear collaborative relationships. Research hotspots mainly focus on safety awareness, system construction, risk assessment, safety culture, emergency management, security system, and other aspects. In the future, emphasis should be placed on building laboratory safety management systems from these hotspots.

Objective In order to prevent the volatilization loss of volatile oil components such as bornyl acetate in Amomum villosum powder during storage, a reasonable and effective storage conditions and storage validity period of Amomum villosum powder were developed, so as to improve the quality stability and food efficiency of terminal products. Methods The samples of Amomum villosum powder in different storage environments [high temperature (35°C), cool (10~15°C) and cold storage (0~5°C)] were sampled every week, and the contents of bornyl acetate and volatile oil were determined respectively. Finally, the trend analysis was carried out according to the content results. Results According to the experimental results, the contents of bornyl acetate and volatile oil in Amomum villosum powder under different storage conditions were quite different. The contents of bornyl acetate and volatile oil in Amomum villosum powder under cold storage conditions were slightly higher than those under shade conditions, but they were significantly higher than those under high temperature storage conditions. Conclusion The research results provide an in-depth analysis of the changes in the main components of Amomum villosum powder under different storage conditions, providing important reference for enterprises to choose the storage method of Amomum villosum powder.

Objective To clarify the detection status and antimicrobial sensitivity of clinically isolated Pseudomonas aeruginosa, assist clinical doctors in using antibiotics based on evidence, delay the rate of bacterial resistance, and intervene purposefully in hospital acquired infections. Methods Pseudomonas aeruginosa cultured, isolated, and identified from clinical samples submitted by our company from January 1, 2023 to December 31, 2023 were collected. According to the latest standard CLSI-M100-ED33, the bacteria were identified using a time-of-flight mass spectrometer, and a fully automated identification and drug susceptibility analysis system was used for drug susceptibility testing. Results Pseudomonas aeruginosa was mainly isolated from elderly men over 60 years old. Sputum was the main source of infection specimens of Pseudomonas aeruginosa. The infected patients were mainly distributed in respiratory and internal medicine departments. The isolated Pseudomonas aeruginosa had high resistance to antibiotics such as amtraxam and ciprofloxacin, and high sensitivity to amikacin and tobramycin, and the overall antibiotic resistance showed a downward trend. Conclusion Strict detection of bacterial resistance and drug resistance genes should be carried out in clinical medicine, so that antibiotics can be used more rationally.