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Objective To clarify the detection status and antimicrobial sensitivity of clinically isolated Pseudomonas aeruginosa, assist clinical doctors in using antibiotics based on evidence, delay the rate of bacterial resistance, and intervene purposefully in hospital acquired infections. Methods Pseudomonas aeruginosa cultured, isolated, and identified from clinical samples submitted by our company from January 1, 2023 to December 31, 2023 were collected. According to the latest standard CLSI-M100-ED33, the bacteria were identified using a time-of-flight mass spectrometer, and a fully automated identification and drug susceptibility analysis system was used for drug susceptibility testing. Results Pseudomonas aeruginosa was mainly isolated from elderly men over 60 years old. Sputum was the main source of infection specimens of Pseudomonas aeruginosa. The infected patients were mainly distributed in respiratory and internal medicine departments. The isolated Pseudomonas aeruginosa had high resistance to antibiotics such as amtraxam and ciprofloxacin, and high sensitivity to amikacin and tobramycin, and the overall antibiotic resistance showed a downward trend. Conclusion Strict detection of bacterial resistance and drug resistance genes should be carried out in clinical medicine, so that antibiotics can be used more rationally.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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