Based on the principle of traditional Chinese medicine quality markers (Q-Markers), this study applies the Analytic Hierarchy Process (AHP) combined with the Indicator-Relatedness Indicator Weighting Method (CRITIC) to preliminarily screen potential quality markers for Abri Herba A radar visualization spectrum is constructed based on the " Cobweb" model to further optimize the screening results, providing scientific evidence and reference for the quality control of Abri Herba.

The chemical components of Abri Herba that are associated with its primary functions (anti-inflammatory, liver-protective, and antioxidant effects) were identified through database retrieval. The AHP method was used to analyze the weight of the factor-layer indicators (efficacy, specificity, and measurability). The CRITIC method was applied to analyze the control-layer data under each factor. The final weights were calculated using the AHP-CRITIC method. A six-dimensional radar chart was constructed based on the integrated AHP-CRITIC scoring results, with the dimensions of " anti-inflammatory, liver-protective, antioxidant, efficacy, specificity, and measurability."

A total of 20 potential quality markers were initially screened using the AHP-CRITIC method. Based on the radar visualization spectrum, luteolin, rheumemodin, catechin, ursolic acid, citric acid, and abrus alkaloids were predicted as potential quality markers for Abri Herba.

The AHP-CRITIC method and the radar visualization spectrum technique based on the " spider-web" model were applied to preliminarily predict the quality markers of Abri Herba, providing a reference for its quality evaluation and future development.

To analyze the effects of Sihuang Shengji decoction on serum activin A (AC-TA), interleukin-1 α (IL-1α), and platelet-derived growth factor (PDGF) after perianal abscess surgery with damp-heat toxicity accumulation.

176 patients with perianal abscess who were treated by surgery in the Fourth People's Hospital of Jinan from December 2022 to December 2024 were selected and randomly divided into routine group and decoction group, with 88 cases in each group. Conventional group: Received conventional postoperative treatment. Decoction group: On the basis of the control group, Sihuang Shengji Decoction was used for treatment. Evaluate the level of TCM syndrome scores of patients; Calculate the improvement time of symptoms in the two groups; The degree of pain of the patients was evaluated by using the VAS score scale. The anal function of the patients was evaluated using the Wexner scoring scale; Detect the maximum systolic pressure of the anal canal and the resting pressure of the anal canal; Detect the levels of VEGF, TGF-β1, SOD, MDA, AC-TA, IL-1α and PDGF. Compare the clinical effective situation.

After treatment, compared with the conventional group, TCM syndrome score, Wexner score, VAS score, MDA, AC-TA, IL-1 α level were decreased (P < 0.01) ; maximum anal tube systolic pressure, anal resting pressure, VE GF, TGF-β1, SOD, and PDGF levels were increased (P < 0.01) ; improvement time of symptoms in the decoction group was shortened (P <0.01) ; total response rate increased in the decoction group (P < 0.01). The incidence of adverse reactions in the decoction group was higher than that in the conventional group (P > 0.05).

For postoperative patients with perianal abscess caused by damp-heat toxicity accumulation, the treatment with Sihuang Shengji decoction can reduce the level of TCM syndrome score, improve anal function, and regulate the levels of serum AC-TA, IL-1α, and PDGF, with remarkable clinical effects.

To observe the treatment of patients with wind-cold type peripheral facial palsy using acupuncture combined with bloodletting therapy based on meridian sinew theory.

A total of 120 patients with wind-cold type peripheral facial palsy treated at the Acupuncture and Physiotherapy Department of Zhengzhou Central Hospital from May 2022 to May 2024 were enrolled. They were randomly divided into an acupuncture group (sinew acupuncture therapy) and a combination group (sinew acupuncture combined with bloodletting at Yifeng acupoint), with 60 cases in each group. The acupuncture group received sinew acupuncture based on meridian sinew theory, with acupoint selection including: Quanliao (SI18), Cuanzhu (BL2), Sibai (ST2), Yangbai (GB14), Taiyang (EX-HN5), Dicang (ST4), Jiache (ST6), and Hegu (LI4). Subcutaneous longitudinal and transverse shallow needling was performed. In the combination group, in addition to the acupuncture points used in the acupuncture group, bloodletting therapy at Yifeng (TE17) was performed. The area around Yifeng acupoint was clamped with the thumb, index, and middle fingers of the left hand, pricked several times, followed by cupping on the pricked area. Five consecutive days of treatment constituted one course, with a 2-day interval between courses. A total of two courses were administered. After the two courses of treatment, the House-Brackmann (H-B) grading scale, Facial Disability Index (FDI), Portmann scale for peripheral facial neuritis, blink reflex, and facial electromyography parameters were observed in both groups before and after treatment to evaluate and compare the clinical efficacy.

After treatment, the FDI scale scores showed that the improvement in the physical function dimension (FDIP) score was significantly greater in the combination group than in the acupuncture group, while the decrease in the social function dimension (FDIS) score was more pronounced in the combination group, with statistically significant differences (P <0.05), indicating that the combined therapy had superior comprehensive improvement in patients' physiological function and social adaptability. The Portmann scale scores showed that the combination group had significantly higher scores than the acupuncture group (P < 0.05), indicating better improvement in facial nerve function in the combination group. The latencies of the orbicularis oris muscle, orbicularis oculi muscle, and nasalis muscle were significantly shortened in both groups compared with before treatment (P < 0.05). The latencies of the orbicularis oris muscle, orbicularis oculi muscle, and nasalis muscle in the combination group were significantly shorter than those in the acupuncture group (P <0.05). After treatment, the latencies of R1, R2, and contralateral R2' waves in both groups were significantly shorter than those before intervention, and the combination group showed significantly shorter latencies than the acupuncture group, with statistically significant differences (P <0.05), indicating that the combination group had better efficacy in repairing facial nerve function.

Acupuncture combined with bloodletting therapy based on meridian sinew theory can effectively improve the clinical symptoms of patients with wind-cold type peripheral facial palsy. Both treatments have significant efficacy in patients with wind-cold type peripheral facial palsy, but the combination of sinew acupuncture and bloodletting at Yifeng acupoint is superior to acupuncture alone. This combined therapy can reduce nerve inflammation, improve local blood circulation, repair damaged nerve fibers, regulate nerve excitability, better promote the recovery of facial nerve function.

To investigate the potential mechanism of Xiaoqinglong Decoction (XQLD) in treating allergic rhinitis (AR) through autophagy and the IL -33/ST2 pathway.

An ovalbumin (OVA)-sensitized mouse model of allergic rhinitis was established. Twenty-four mice were randomly assigned to four groups: control group, model group, dexamethasone (Dex) group, and XQLD group. All groups except the control received intraperitoneal injections of PBS containing 50 μg OVA and 2 mg aluminum hydroxide on days 1, 7, and 14 for sensitization. From days 21 to 27, mice were challenged intranasally with 400 μg OVA every 24 hours (4 total challenges). Interventions: The XQLD group received XQLD (10. 14 g/kg), the dexamethasone group received dexamethasone disodium phosphate (1 mg/kg), while the model and control groups received equivalent volumes of PBS. All treatments were administered once daily via gavage for 7 days. At 24 h after the final challenge, nasal symptoms (sneezing, scratching, rhinorrhea) were evaluated using a double-blind protocol. Serum was collected for the detection of OVA-specific IgE (OVA-sIgE) and Th1/Th2 cytokines (IL-2, IL-12, IL-5, IL-13) using ELISA. Nasal mucosa tissues underwent Hematoxylin and Eosin (H&E) staining, and immunohistochemical analysis was performed for IL-2, IL-12, IL-5, IL-13, IL-33, ST2, Beclin1, and P62.

compared to the control group, mice in the model group exhibited significantly elevated symptom scores (P < 0.01). The nasal mucosa showed pathological changes including epithelial desquamation, vasodilation, glandular hyperplasia, and extensive inflammatory cell infiltration. Serum OVA-sIgE, IL-5, and IL-13 levels were significantly increased (P < 0.01), while IL-2 and IL-12 levels were decreased (P < 0.01). In nasal mucosa tissue, the protein expression of IL-5, IL-13, IL-33, ST2, and P62 was elevated (P < 0.01), whereas the expression of IL-2, IL-12, and Beclin1 was decreased (P < 0.01). Compared to the model group, mice treated with XQLD and Dex groups showed significantly reduced symptom scores (P < 0.01) and improved nasal mucosal pathology. Serum OVA-sIgE, IL-5, and IL-13 levels decreased (P <0.01), while IL-2 and IL-12 levels increased (P <0.01). In nasal mucosa tissue, the protein expression of IL-2, IL-12, and Beclin1 increased (P <0.01), while the expression of IL-5, IL-13, IL-33, ST2, and P62 decreased (P < 0.01). No statistically significant differences were observed between the XQLD group and the Dex group regarding symptom scores, serum IL-2, IL-12, IL-5, OVA- sIgE levels, and nasal mucosa tissue IL-2, IL-12, IL-5, IL-13, Beclin1, and P62 protein expression (P >0.05).

XQLD alleviates nasal symptoms and pathological damage in AR mice by synergistically regulating Th1/Th2 immune balance through autophagy activation and IL -33/ST2 pathway inhibition.

To investigate the clinical efficacy of fire needle pricking combined with Kinesio taping in the treatment of lateral femoral cutaneous neuritis caused by military training, and to analyze its mechanism from the perspective of traditional Chinese medicine theory.

A total of 70 patients diagnosed with lateral femoral cutaneous neuritis induced by military training in the Department of Traditional Chinese Medicine Rehabilitation, No. 910 Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army from November 2023 to November 2024 were enrolled. They were randomly divided into a control group (fire needle pricking alone) and an experimental group (fire needle pricking combined with Kinesio taping), with 35 cases in each group. Traditional Chinese medicine (TCM) syndrome scores, Visual Analog Scale (VAS) scores, Japanese Orthopaedic Association (JOA) scores, pain mediators (PGE₂, 5-HT), and SF-36 scores were evaluated in both groups.

After treatment, the TCM syndrome scores, VAS scores, and levels of PGE₂ and 5-HT in the experimental group were significantly lower than those in the control group (P <0.05). The JOA scores, as well as the SF-36 subscale scores for physical function, emotional function, cognitive function, social function, role function, and general health, were significantly higher in the experimental group than in the control group (P < 0.05). The total effective rate in the experimental group was higher than that in the control group (P < 0.05).

Fire needle pricking combined with Kinesio taping demonstrates significant therapeutic effects in treating lateral femoral cutaneous neuritis caused by military training. It can rapidly alleviate pain and improve sensory disturbances. The mechanism may be associated with inhibiting local inflammatory responses and promoting nerve repair. This combined therapy is safe and easy to operate, making it suitable for widespread application in the prevention and treatment of military training-related injuries.

To analyze the effects of early limb rehabilitation training combined with traditional Chinese medicine fumigation on patients with hemiplegia after cerebral infarction (Cerebral Infarction, CI).

A retrospective analysis was conducted on the clinical data of 128 patients with hemiplegia after CI from October 2022 to October 2024. Among them, 64 patients received conventional treatment and rehabilitation training as the control group, while another 64 patients underwent early limb rehabilitation training combined with traditional Chinese medicine fumigation as the study group. The cerebral circulation hemodynamics indicators of both groups were analyzed, and assessments were performed using the Montreal Cognitive Assessment (MoCA), Mini-Mental State Examination (MMSE), Fugl-Meyer Assessment (FMA), Functional Composite Assessment (FCA), and Berg Balance Scale (BBS).

Before treatment, there were no statistically differences in cerebral circulation hemodynamics indicators between two groups (P > 0.05). After treatment, the study group higher minimum blood flow velocity and minimum blood flow volume compared to the control group(P < 0.01), along with significantly higher critical pressure and cerebrovascular peripheral resistance (P <0.05). Before treatment, there were no significant differences in MoCA and MMSE scores between two groups (P >0.05). After treatment, the study group showed higher MoCA and MMSE scores (P <0.05, P < 0.01). Before treatment, there were no significant differences in limb motor function between two groups (P > 0.05). After treatment, the study group demonstrated higher upper and lower limb motor function scores (P <0.01). Before treatment, there were no significant differences in motor balance function between two groups (P > 0.05). After treatment, the study group higher FCA and BBS scores (P < 0.01).

Early limb rehabilitation training combined with traditional Chinese medicine fumigation yields favorable outcomes for patients with hemiplegia after CI, not only improving cognitive function and mental state but also enhancing limb motor function and motor performance, while also contributing to the stabilization of cerebral circulation hemodynamics indicators.

To explore the clinical efficacy and safety research on children with anorexia-spleen deficiency and dyspepsia based on Ganji Powder combined with Zengshi Oral Paste.

Children with anorexia attending the outpatient clinic of Tongling Traditional Chinese Medicine Hospital from July 2022 to December 2023 were selected for the study, and were divided into four groups using the random number table method; the Saccharomyces boulardii group (36 cases) was treated with a single Saccharomyces boulardii orally, the Ganji Powder group (41 cases) was treated with Ganji Powder externally applied to the acupoints alone, the Zengshi Oral Paste group (49 cases) was treated with Zengshi Oral Paste orally alone, and the combined group used the The combined group was treated with Ganji Powder applied externally to two acupoints, Shenque and Mingmen, and combined with Zengshi Oral Paste (an in-hospital preparation). All four groups were treated for one treating course. The clinical efficacy of the children in the four groups, the time for the children's food intake to return to normal and the amount of increase in body mass, the points of Chinese medicine symptoms, the level of nutritional indexes, the adverse reactions and the six-month follow-up were observed.

The total effective rate was 89.47% (68/76) in the combined group, 58.33% (21/36) in the Saccharomyces boulardii group, 70.73% (29/41) in the Ganji Powder group, and 75.51% (37/49) in the Zengshi Oral Paste group. The total effective rate of the combined group and the time for the return of the normal food intake and the increase of the body mass of the children, the Chinese medicine symptom scores of the main evidence and the secondary evidence, the tongue and pulse, and the levels of the proteins, the body fats, the muscle mass, the basal metabolic rate, the transferrin, the retinol-binding protein, the pre-albumin Nutritional indicators such as protein, body fat, muscle mass, basal metabolic rate, transferrin, retinol-binding protein, prealbumin, haemoglobin, average haemoglobin content and dihydroxyvitamin D were all better than those of the Saccharomyces boulardii group, the noma group and the Zengshi Oral Paste group (P <0.05, P < 0.01); All indicators of the Ganji Powder and Zengshi Oral Paste were superior to those of Saccharomyces boulardii group. (P <0.05). There were no serious adverse reaction situations during the treatment period of each group, and the relapse rate of the combined group was the lowest after six months of follow-up.

The treatment of children's anorexia with spleen deficiency and dyspepsia based on Ganji Powder and Zengshi Oral Paste can significantly reduce children's clinical symptoms, and the children's gastrointestinal function recovered well, with a significant clinical effect and high safety.

To explore the clinical effect of modified Shaoyao Decoction combined with acupoint embedding in the treatment of patients with ulcerative colitis (UC).

A total of 120 patients with internal damp-heat type UC who visited the Department of Anorectal Diseases of the Second Affiliated Hospital of Hunan University of Chinese Medicine from April 2023 to April 2025 were prospectively selected. They were grouped using the random number table method and assigned by independent researchers. Although the intervention measures limited the blinding of patients, the assessment of endoscopic outcomes strictly followed the blinding principle. The treatment was carried out by endoscopists who were unaware of the grouping situation. The control group (with 0 cases dropped out and 60 cases ultimately included) was given Western medicine and acupoint embedding treatment, while the combined group (with 0 cases dropped out and 60 cases ultimately included) was treated with modified Shaoyao Decoction on this basis. The treatment courses are all 6 weeks. The changes of TCM symptoms scores and ulcerative colitis endoscopic index of severity (UCEIS) before and after treatment were compared between groups. The expression levels of Th17/Treg cell balance-related indicators [IL-22, IL-21, IL-10, transforming growth factor-β (TGF-β)] were detected, and the clinical efficacy and safety of the two groups before and after treatment were evaluated.

After 6 weeks of treatment, the total clinical effective rate in the combined group was 95.00% (57/60), which was much higher than 83.33% (50/60) in the control group (χ² = 4.227, P < 0.05). The UCEIS scores, TCM symptoms scores and levels of IL-22 and IL-21 in the two groups after treatment were significantly reduced compared with those before treatment (P < 0.05), and the above scores and levels were lower in the combined group than those in the control group (P <0.05). The levels of IL-10 and TGF-β were significantly enhanced in the two groups compared to before treatment (P < 0.05), and the combined group had higher levels (P <0.05). There were no obvious adverse reactions in the two groups after treatment.

The modified Shaoyao Decoction combined with acupoint embedding thread can effectively improve the symptoms and therapeutic effect of UC patients, and can reduce the UCEIS scores. Additionally, it can also reduce the inflammatory response by regulating the expression levels of Th17/Treg cell balance-related indicators, with good safety.

To observe the effect of Jianpi Anshen Decoction combined with warm acupuncture at Periumbilical Four-Sided Points on the treatment of patients with chronic insomnia heart-spleen deficiency syndrome.

A total of 92 patients with chronic insomnia heart-spleen deficiency syndrome treated in Ma'anshan Shiqiye Hospital from January 2020 to September 2024 were selected and divided into experimental group (n=46) and control group (n = 46) by random number table method. The control group was treated with warm acupuncture at Periumbilical Four-Sided Points, the experimental group received Jianpi Anshen decoction on the basis of the control group. Both groups were treated for 3 months. The TCM symptom score, sleep structure, insomnia degree, sleep quality, clinical efficacy, neurotransmitter and adverse reactions were compared between the two groups.

After treatment, the scores of TCM syndrome, wake after sleep on set (WASO), sleep latency (SOL), insomnia Severity Index Scale (ISI) and Pittsburgh Sleep Quality Index (PSQI) were all decreased in two groups, and the experimental group was lower (P < 0.05). After treatment, total sleep time (TST) and sleep efficiency (SE) were increased in both groups, and higher in the experimental group (P < 0.05). The experimental group with total effective rate (93.65%) was higher than the control group (82.61%) (P <0.05). After treatment, serum 5-hydroxytryptamine (5-HT) and glycated serum albumin (GA) levels were increased in both groups, and higher in experimental group (P < 0.05). After treatment, serum dopamine (DA) level was decreased in both groups, and lower in experimental group (P < 0.05). During the treatment period, there were no obvious adverse reactions in both groups. Within 3 months of treatment, there was no significant difference in recurrence rate between the two groups (P > 0.05).

Jianpi Anshen Decoction combined with warm acupuncture at Periumbilical Four-Sided Points in the treatment of chronic insomnia patients with heart-spleen deficiency syndrome is effective, can improve the sleep structure and sleep quality of patients, reduce insomnia symptoms, regulate neurotransmitters, good safety, and good short-term prognosis.