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Clinical Observation of Danggui Niantong Decoction Combined with Celecoxib in the Treatment of Cervical Spondylotic Radiculopathy with Wind-Damp-Heat Obstruction Syndrome
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Ke AI, Lei WANG*, Jun YANG, Jieneng CHEN
Acta Chinese Medicine and Pharmacology | 2026, 54(7) : 103 - 108
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Acta Chinese Medicine and Pharmacology | 2026, 54(7): 103-108
Clinical Observation of Danggui Niantong Decoction Combined with Celecoxib in the Treatment of Cervical Spondylotic Radiculopathy with Wind-Damp-Heat Obstruction Syndrome
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Ke AI, Lei WANG*, Jun YANG, Jieneng CHEN
Affiliations
  • Huanggang Central Hospital, Huanggang Dabie Mountain Medical Center, Huanggang 438000, China
Published: 2026-07-20 doi: 10.19664/j.cnki.1002-2392.260149
Outline
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Objective:

To evaluate the efficacy of celecoxib combined with Danggui Niantong Decoction in the treatment of cervical spondylotic radiculopathy Wind-Damp-Heat Obstruction syndrome).

Methods:

A total of 98 patients with cervical radiculopathy (Wind-Damp-Heat Obstruction syndrome) admitted to the orthopedics and inpatient department of Huanggang Central Hospital from January 2023 to December 2023 were selected as the study objects, and were divided into 2 groups according to random number table method, with 49 cases each. The control group was treated with celecxib on the basis of cervical traction therapy, and the experimental group was treated with Danggui Niantong Decoction on the basis of control group for 4 weeks. The clinical efficacy, TCM symptom score, VAS scale score, NDI questionnaire, CASCS scale score, serum inflammatory indicators IL-1β, IL-6β, TNF-αlevel and incidence of adverse reactions were compared between the two groups.

Results:

The total effective rate of experimental group after treatment was significantly higher than that of control group (P < 0.05). After treatment, TCM symptom score of two groups was significantly decreased, and the test group was lower than the control group(P < 0.05). VAS and NDI scores after treatment were lower than before treatment, CASCS scores were higher than before treatment, and the change range of experimental group was higher than that of control group (P <0.05). The serum levels of IL-1β, IL-6β and TNF-αin 2 groups after treatment were lower than before treatment, and the experimental group was lower than the control group(P < 0.05).

Conclusion:

Danggui Niantong Decoction combined with celecxib has a good effect in the treatment of cervical spondylopathy patients with rheumatic heat arthralgia nerve root type, which can significantly improve cervical spine function and clinical symptoms, reduce the level of pain and inflammatory factors, and is safe, worthy of clinical promotion.

Danggui Niantong Decoction  /  Wind-Damp-Heat obstruction syndrome  /  Cervical spondylotic radiculopathy  /  Celecoxib
Ke AI, Lei WANG, Jun YANG, Jieneng CHEN. Clinical Observation of Danggui Niantong Decoction Combined with Celecoxib in the Treatment of Cervical Spondylotic Radiculopathy with Wind-Damp-Heat Obstruction Syndrome[J]. Acta Chinese Medicine and Pharmacology, 2026 , 54 (7) : 103 -108 . DOI: 10.19664/j.cnki.1002-2392.260149
Year 2026 volume 54 Issue 7
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doi: 10.19664/j.cnki.1002-2392.260149
  • Receive Date:2024-12-31
  • Online Date:2026-09-17
  • Published:2026-07-20
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  • Received:2024-12-31
  • Revised:2025-11-25
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    Huanggang Central Hospital, Huanggang Dabie Mountain Medical Center, Huanggang 438000, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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