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Research Progress on the Regulation of TLR4/NF-κB Pathway by Traditional Chinese Medicine in the Intervention of Epilepsy
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Liyang WEN1, 2, Peng Liu2, Jian Xue2, Guangyu Cheng2, Na Qi1, *
Acta Chinese Medicine and Pharmacology | 2026, 54(7) : 122 - 128
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Acta Chinese Medicine and Pharmacology | 2026, 54(7): 122-128
Research Progress on the Regulation of TLR4/NF-κB Pathway by Traditional Chinese Medicine in the Intervention of Epilepsy
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Liyang WEN1, 2, Peng Liu2, Jian Xue2, Guangyu Cheng2, Na Qi1, *
Affiliations
  • 1.Heilongjiang University of Chinese Medicine, Harbin 150040, China
  • 2.The First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, China
Published: 2026-07-20 doi: 10.19664/j.cnki.1002-2392.260152
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Epilepsy is a neurological disorder characterized by complex and diverse pathogenesis, involving abnormal activation of multiple signaling pathways. In recent years, with the in-depth study of the pathogenesis of epilepsy, traditional Chinese medicine (TCM) has shown unique advantages as a traditional treatment method in the treatment of epilepsy. Especially, TCM has exerted significant anti-epileptic effects by regulating the Toll-like receptor 4 (TLR4) nuclear factor NF-κB signaling pathway. This article aims to review the latest research progress of TCM in regulating the TLR4/NF-κB pathway, focusing on analyzing the mechanisms of active components and compound prescriptions of traditional Chinese medicine via the TLR4/NF-κB pathway, in order to provide reference and inspiration for future research.

Traditional Chinese medicine  /  Epilepsy  /  TLR4  /  NF-κB
Liyang WEN, Peng Liu, Jian Xue, Guangyu Cheng, Na Qi. Research Progress on the Regulation of TLR4/NF-κB Pathway by Traditional Chinese Medicine in the Intervention of Epilepsy[J]. Acta Chinese Medicine and Pharmacology, 2026 , 54 (7) : 122 -128 . DOI: 10.19664/j.cnki.1002-2392.260152
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Article Info
doi: 10.19664/j.cnki.1002-2392.260152
  • Receive Date：2025-09-22
  • Online Date：2026-09-17
  • Published：2026-07-20
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History
  • Received：2025-09-22
  • Revised：2026-03-26
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Affiliations
    1.Heilongjiang University of Chinese Medicine, Harbin 150040, China
    2.The First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
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Genus		 种数
Number of
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Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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