Qingfengteng（Caulis Sinomenll），as the dried cane of Qingteng［Sinomenium acutum（Thunb.）Rehd. et Wils.］and Maoqingteng［Sinomenium acutum（Thunb.）Rehd. et Wils. var. cinereum Rehd. et Wils］，is now included in the Chinese Pharmacopoeia. It has a long history of being used as the medicine and rich literature records，and has profound cultural and medicinal value. In this paper，the research，pharmacological effects，clinical application and adverse reactions of Qingfengteng（Caulis Sinomenll）were summarized. On this basis，the quality markers of Qingfengteng（Caulis Sinomenll）were predicted by using the quality markers of traditional Chinese medicine（Q-Marker）as a guide，in order to provide an important reference for its quality control and research，and provide relevant reference for further development，utilization and research of Qingfengteng（Caulis Sinomenll）.

Nervous system related diseases are the most common diseases that threaten human life，health and quality of life.“Brain-gut axis” is a two-way interactive pathway between brain and intestine. Intestinal flora affects the occurrence and development of nervous system related diseases through multiple pathways of brain-gut axis，forming a complex network mechanism. This paper discussed the theory of “heart and small intestine being exterior-interiorly related” in traditional Chinese medicine，the key role of intestinal flora in the brain-gut axis and its close correlation with the occurrence and development of nervous system related diseases，so as to provide new ideas for the re-understanding and innovative development of the theory of “heart and small intestine being exterior-interiorly related” in traditional Chinese medicine and the theory of “brain-gut axis” in modern medicine.

Youbing Shiwei（Pyrrosia petiolosa），a medicinal plant belonging to the Pyrrosia genus in the family Polypodiaceae，is commonly used as a traditional Chinese medicine to treat pyelonephritis，chronic bronchitis and urinary calculi. In this paper，CNKI，PubMed，Web of Science and other databases were searched for domestic and foreign published literatures related to Youbing Shiwei（Pyrrosia petiolosa），and the chemical components and bioactivity studies of Youbing Shiwei（Pyrrosia petiolosa）in the past forty years were systematically combed and summarized. It is found that more than 100 compounds have been isolated from Youbing Shiwei（Pyrrosia petiolosa），including flavonoids，triterpenoids，lignins，phenols and others. The extract of Youbing Shiwei（Pyrrosia petiolosa）has significant bioactivities，such as anti-oxidation，anti-bacterial，anti-inflammatory，diuretic，promote wound healing，anti-kidney stones and anti-diabetes effects. This paper can provide theoretical reference and scientific basis for further systematic research and clinical development of Youbing Shiwei（Pyrrosia petiolosa）medicinal resources.

Zuogui Pill（左归丸），from Jingyue Quanshu，has been used clinically for more than 400 years. It is a classic prescription for the treatment of kidney Yin deficiency. It has the effect of nourishing Yin and tonifying kidney，supplementing essence and replenishing marrow，and is widely used in the treatment of osteoporosis，knee osteoarthritis and other diseases. In recent years，more and more studies have shown its efficacy in the treatment of premature ovarian failure（POF）. This article summarized the mechanism of the treatment of POF and the literature in recent years from the aspects of inhibiting cell apoptosis and autophagy，improving sex hormone levels，regulating the expressions of growth differentiation factor 9（GDF-9）and bone morphogenetic protein-15（BMP-15），up-regulating the expressions of connexin37（Cx37）and Connexin43（Cx43），regulating the hypothalamic pituitary ovarian axis（HPOA），improving ovarian angiogenesis and anti osteoporosis. And it participated in regulating the PI3K/Akt/mTOR and GDF-9/Smad2 signaling pathways，confirming the therapeutic effect of Zuogui Pill on POF from a molecular mechanism perspective. And through the summary of Zuogui Pill，it is found that whether it is a single treatment，or combined with western medicine or acupuncture and moxibustion treatment，it can significantly improve the symptoms of patients，reduce adverse reactions，and has definite clinical efficacy and high safety，which is worthy of clinical promotion and application. This article comprehensively analyzed the current status of Zuogui Pill in the treatment of POF through basic and clinical research，and proposed shortcomings and improvements in current basic and clinical research，providing relevant basis for future in-depth research and clinical application of the formula，as well as the development of new drugs for the treatment of POF

Psoriasis is a chronic inflammatory skin disease，and its pathogenesis is related to endocrine disorders，immune dysfunction and other factors. The patients with psoriasis during pregnancy have obvious improvement or self-healing tendency. Studies show that 55% of patients with psoriasis during pregnancy have improved，and estradiol is the most potent natural estrogen. And an increase in estrogen levels，especially relative to progesterone，is associated with the improvement of psoriasis. As an important hormone regulating substance，estrogen and progesterone have many biological activities，such as regulating endocrine secretion，inhibiting inflammatory reaction and promoting skin repair，which is consistent with the principle of balance between Yin and Yang in the theory of “Yang transforming into Qi，while Yin constituting form”. Yangqi is responsible for dispersing and transforming，while Yin fluid is responsible for nourishing and shaping. According to the theory of “Yang transforming into Qi，while Yin constituting form”，they are interdependent and mutually restrictive，jointly maintaining the life activities. Based on the theory of “Yang transforming into Qi，while Yin constituting form”，the keratinocytes of psoriasis are excessively proliferated，which belongs to the deficiency of Yang transforming，and the Yin forming is too much. Estrogen belongs to Yang，progesterone belongs to Yin，and estrogen and progesterone cooperate to adjust the balance of Yin and Yang，thus improving psoriasis.

Huangqi（Astragali Radix），as a clinically used traditional Chinese medicine for tonifying deficiency in clinical practice，has a long history of clinical application along with its medicinal properties. This article focused on the pharmacological effects of Huangqi（Astragali Radix）and the network pharmacology based on Huangqi（Astragali Radix）-Danshen（Salviae Miltiorrhizae Radix et Rhizoma），Huangqi（Astragali Radix）-Danggui（Angelicae Sinensis Radix），Huangqi（Astragali Radix）-Ezhu（Curcumae Rhizoma），Huangqi（Astragali Radix）-Baizhu（Atractylodis Macrocephalae Rhizoma），Huangqi（Astragali Radix）-Chuanxiong（Chuanxiong Rhizoma），Huangqi（Astragali Radix）-Renshen（Ginseng Radix et Rhizoma），Huangqi（Astragali Radix）-Shanyao（Dioscoreae Rhizoma），Huangqi（Astragali Radix）-（Puerariae Lobatae Radix）and Huangqi（Astragali Radix）-Honghua（Carthami Flos）in recent years，as well as clinical studies of the commonly-used pairs like Huangqi（Astragali Radix）-Danggui（Angelicae Sinensis Radix），Huangqi（Astragali Radix）-Danshen（Salviae Miltiorrhizae Radix et Rhizoma），Huangqi（Astragali Radix）-Ezhu（Curcumae Rhizoma）and Huangqi（Astragali Radix）-Chuanxiong（Chuanxiong Rhizoma）on the Chinese Network of Knowledge（CNKI），in a review of clinical applications and modern experimental studies. Application and modern experimental studies were summarized. The above content provided a reference and basis for systematically revealing the connotation and interpretation of Huangqi（Astragali Radix）and its drug pairs as well as the scientific application of Huangqi（Astragali Radix）combinations. This paper summarized the pharmacological effects of Huangqi（Astragali Radix）and the clinical application of Huangqi（Astragali Radix）drug pairs and the current status of modern research，in-depth analysis of the scientificity of Huangqi（Astragali Radix）and its drug pairs，to provide a basis for better scientific interpretation of Huangqi（Astragali Radix）and its drug pairs of the mechanism of action，an important basis for systematic research on the theory of Huangqi（Astragali Radix）drug pairs of the matching method，and a new way of thinking for the further development and utilization of Huangqi（Astragali Radix）and its drug pairs.

Gegen Qinlian Decoction（葛根芩连汤，GQD），a classical formula recorded in the Treatise on Febrile Diseases，possesses the efficacy of relieving the exterior and clearing the interior，ascending the clear and stopping dysentery. Traditionally，it has been primarily used to treat diarrhea or dysentery caused by damp-heat. Given the similarities in pathological mechanisms and primary symptoms between traditional indications of GQD and modern gastrointestinal inflammatory diseases，particularly ulcerative colitis（UC），GQD has been widely used in modern clinical practice to treat such diseases. The research has shown that the mechanism of GQD treating UCinvolves multiple pathways and targets，including regulating immune response，protecting intestinal mucosal barrier，antioxidant stress and inhibiting inflammatory response. The realization of these mechanisms is intricately linked to the sophisticated regulatory network among cytokines. Moreover，the significance of cytokines in the pathogenesis of UChas become increasingly prominent. The imbalance between pro-inflammatory and anti-inflammatory cytokines leading to immune dysregulation is considered a critical factor influencing the progression and prognosis of UCand has become a focal point of current research. Based on this，this study systematically reviewed the mechanism of Gegen Qinlian Decoction in the treatment of UCfrom the perspective of cytokines，and explored it in depth from pro-inflammatory cytokines and anti-inflammatory cytokines，aiming to provide further theoretical support and reference for the rational clinical application of GQD.