Latest ArticlesTo study the therapeutic mechanism of resolving blood stasis and regulating tendons acupuncture combined with Zhuyu Zhitong Decoction（逐瘀止痛汤）in the treatment of lumbar disc herniation.
Eighty-six patients diagnosed with lumbar disc herniation were selected and divided into two groups according to random number table. Forty-three cases in the reference group were treated with resolving blood stasis and regulating tendons acupuncture，and the other forty three cases in the study group were treated with resolving blood stasis and regulating tendons acupuncture and Zhuyu Zhitong Decoction. The clinical efficacy，TCM syndrome scores，inflammatory factor levels and lumbar function of the two groups were observed and compared.
The total effective rate of the study group was 95.35%，higher than that（74.42%）of the control group. The difference was statistically significant（P<0.05）. After treatment，the lumbar function in the study group was higher than that in the reference group，and the difference was statistically significant（P<0.05）. After treatment，the levels of interleukin-6（IL-6），interleukin-17（IL-17）and tumor necrosis factor-α（TNF-α）in the study group were lower than those in the reference group，and the difference was statistically significant（P<0.05）. After treatment，compared with those of the reference group，VAS score and muscle strength were higher and ODIscore was lower in the study group，and the differences were statistically significant（P<0.05）. After treatment，compared with those of the reference group，the pelvic lateral inclination，pelvic tilt angle and sagittal plane flat axis of the study group were smaller，and the lumbar lordosis angle was larger. The differences were statistically significant（P<0.05）.
The patients with lumbar disc herniation were treated by resolving blood stasis and regulating tendons acupuncture and Zhuyu Zhitong Decoction，which can effectively improve the function of the lumbar spine，reduce the inflammatory response of the body and promote the recovery of the patients，and have high clinical application value.
Functional dyspepsia（FD）is a relatively common digestive disease in clinical practice，and there is no functional dyspepsia in traditional Chinese medicine，but according to its clinical manifestations，it can be included in the categories of“stuffiness and fullness”，“gastric pain”，“stagnation”and“accumulation”. Through reviewing the literature，the author has found that FD is located in the stomach and has a close relationship with liver，spleen and heart，mostly due to the onset of external evils，dietary irregularities and deficiency of spleen and stomach，which ultimately leads to an imbalance in the function of spleen ascending and stomach descending，and an imbalance in the human body＇s Qi，thus leading to the occurrence of FD. Zhizhu Pill（枳术丸）was firstly transformed from ZHANG Zhongjing＇s Zhizhu Decoction（枳术汤），then improved by WANG Kuang in Song Dynasty and LIU Wansu in Jin Dynasty，and was firstly mentioned in Discussion of Internal and External Injuries and Prohibition of Dietary Use of Medicines for Internal and External Injuries by LI Dongyuan. Zhizhu Pill has the efficacy of strengthening spleen and eliminating stuffiness and fullness，and has been widely used by doctors in the following generations for the treatmentof diseases of spleen and stomach. Clinical studies have found that Zhizhu Pill is often used in the treatment of FD，either as a single formula with additions and subtractions，or in combination with Xiangsha LiujunziDecoction（香砂六君子汤），Chaihu Shugan Powder（柴胡疏肝散），western medicines and moxibustion，in order to improve the efficacy of the treatment，minimize the side-effects and reduce the recurrence rate. Experimental studies have found that the mechanism of action of Zhizhu Pill for FDmay be related to the regulation of the brain-gutaxis，reduction of visceral hypersensitivity，regulation of gastrointestinal function and restoration of intestinal flora dysbiosis. This paper discussed the theoretical research，clinical experiment and mechanism of action，aiming to study the progress of Zhizhu Pill in treating FD，in order to provide broader ideas for clinical diagnosis and treatment.
How to promote rapid regeneration of the musculoskeletal system is an urgentproblem to be solved in the treatment of complex and difficult orthopedic diseases. Lurong（Cervi Cornu Pantotrichum）is the only reproducible mammalian organ discovered so far，and its stem cells have efficient regenerative effects on bone tissue，cartilage，nerves，blood vessels and skin. The application of Lurong（Cervi Cornu Pantotrichum）related drugs locally or systemically，combined with variousminimally invasive techniques in orthopedics，is expected to achieve the goal of early rehabilitation for orthopedic patients. This paper reviewed the functions and clinical applications of Lurong（Cervi Cornu Pantotrichum）related products，providing new ideas for regenerative medicine treatment models in the orthopedic fields.
To study the clinical study of Longqing Tablets（癃清片）in the treatment of chronic prostatitis with dampness-heat stasis.
A total of 80 patients diagnosed with chronic prostatitis with damp-heat and blood stasis were selected and divided into two groups according to random number table. Forty cases in control group were treated with Tamlosin Hydrochloride Sustained-Release Tablet，and the other 40 cases in study group were treated with Longqing Tablets. The clinical efficacy，chronic prostatitis syndrome score index（NIH-CPSI），urodynamic indexes and prostatic fluid related indexes of the two groups were compared.
The total effective rate of the study group was95.00%，higher than that（77.50%）of the control group，and there was statistical significance（P<0.05）. After treatment，the NIH-CPSIscore of the study group was lower than that of the control group，and the difference was statistically significant（P<0.05）. After treatment，compared with those of the control group，themaximum urine flow rate and maximum bladder volume in the study group were higher，and the changes of residual urine volume and maximum detrusor pressure were lower，and there was statistical significance（P<0.05）. After treatment，the levels of monocyte chemoattractant protein-1（MCP-1），macrophage-stimulating factor（M-CSF），vascular cell adhesion molecule 1（VCAM-1），interleukin-10（IL-10）and C-reactive protein（CRP）in the study group were lower than those in the control group，and the differences were statistically significant（P<0.05）.
After Longqing Tablets treating patients with chronic prostatitis with dampness-heatand blood stasis，the clinical symptoms can be alleviated，the inflammatory response can be effectively reduced and the antibacterial effect is good. It can promote the recovery of the patients，and have high clinical application value.
Ischemic stroke is a common and severe cerebrovascular disease primarily caused by insufficient blood supply to the brain，resulting in significant damage to brain tissue and severely impacting patients＇quality of life. Despite the introduction of modern medical treatments such as recombinant tissue plasminogen activator（rt-PA）thrombolys is and mechanical thrombectomy，issues like time window limitations and bleeding risks remain challenging. In recent years，traditional Chinese medicine（TCM）hasmade remarkable progress in the treatment of ischemic stroke. TCM not only overcomes the time window limitations of traditional thrombolytic therapy but also significantly reduces bleeding risks. Among the potential treatments，Chinese herbal glycosides have been extensively used for various diseases，including ischemic stroke. This paper focused on the relationship between Chinese herbal glycosides and ischemic stroke，summarizing their mechanisms of action in antioxidation，anti-inflammation，maintenance of vascular function，neuroprotection，and regulation of gutmicrobiota. The study aimed to provide novel perspectives and approaches for the clinical treatment of ischemic stroke.
LU Zhizheng，the master of traditional Chinese medicine，is deeply studying and thinking about the spleen and stomach theory and the theory of febrile disease，taking into account the changes of modern etiology and pathogenesis. His academic experience has been summed up into sixteen words：“holding spleen and stomach as the center of the body，regulating the four limbs and other Zang-Fu organs，delighting the mood，regulating the ascending and descending，giving attention tomoistening and drying and maintaining normal intake and transformation”. This article took spleen and stomach diseases as the core，analyzed the syndrome differentiation thought contained in giving attention to“giving attention tomoistening drying and maintaining normal intake and transformation”.“Giving attention tomoistening and drying”is in accordance with the characteristics of“stomach preferring moistening and disliking drying”and“spleen preferring drying and disliking dampness”. At the same time，it is not limited to Zang-Fu organs，with syndrome differentiation as the focus. It also sorted out the medication strategy of both moistening and drying，supplemented by regulating Qi and delighting the mood，so as to achieve the treatment purpose of maintaining normal intake and transformation.
Pine plant polysaccharides（PPPS）have complex structural characteristics and various biological activities，such as immune regulation，anti-tumor，anti-oxidation and regulation of blood glucose. More and more studies have shown that polysaccharides are one of the main active ingredients of pine plants and play an indispensable role in the medicinal value of pine plants. In recentyears，a large number of studies have been carried outon PPPS，including the extraction，separation，structural identification and activity research of PPPS. However，at present，the research on PPPS is not deep enough. The structure of polysaccharides is only preliminarily analyzed. The crude polysaccharides are used in the study of activity，and only simple efficacy evaluation is made. The specific mechanism of action and the structure-activity relationship of polysaccharides are not clear. At present，the extraction of PPPSmainly uses hot water extraction，ultrasonic assisted extraction，microwave assisted extraction，enzyme assisted extraction and other processes. In terms of purificationmethods，anion exchange chromatography and dextran gel chromatography were mainly used. In the aspect of chemical structure analysis，the molecular weight，monosaccharide composition and proportion，connection mode and so on were mainly studied. In terms of biological activity，the activities of immune regulation，anti-virus and anti-tumor were studied. This paper summarized the research data in this field in the past ten years aswell as the research background，extraction，purification，structural characteristics and biological activity of PPPS，in order to provide some research prospects for the study of PPPS.
To explore the curative effect of Diwu Yanggan Prescription（地五养肝方）combined with laparoscopic hepatectomy in the treatment of primary liver cancer and the prevention of recurrence.
A total of74 patients with primary liver cancer（admitted from January 2020 to September2022）were included，and the patientswere divided into a simple operation group（37 cases）and a combined traditional Chinese and Western medicine group（37 cases）by random number table method. All patients in the simple operation group were treated with laparoscopic hepatectomy，while those in the combined traditional Chinese and Western medicine group were treated with Diwu Yanggan Prescription combined with laparoscopic hepatectomy. During the study，there were 2 cases shedding in the combined traditional Chinese and western medicine group and 1 case in the simple operation group. The data in each group was observed，including the efficacy，visual analogue scale（VAS）3 and 5 days after surgery，complications，postoperative exhaust and first time，length of hospital stay，changes in total TCM symptom scores before and after treatment，the changes of direct bilirubin（DBIL），aspartate transaminase（AST）and glutamic pyruvic transaminase（ALT），the levels of interleukin-6（IL-6），C-reactive protein（CRP）and tumor necrosis factor alpha（TNF-α）7 days after surgery，the levels of alpha-fetoprotein（AFP）and matrix metalloproteinase-9（MMP-9）before and after treatment，the tumor recurrence rate 6months and 1 year after surgery.
The total effective rate of the combined traditional Chinese and Western medicine group was higher than that of the simple operation group（P<0.05）. The VAS scores of the combined traditional Chinese and Western medicine group were lower than those of the simple operation group 3 d and 5 d after surgery（P<0.05）. The complication rate of integrated traditional Chinese and Western medicine group was lower than that of the simple operation group（P<0.05）. The postoperative exhaust，the first time and the length of hospital stay in the combined traditional Chinese and Western medicine group were shorter than those in the simple operation group（P<0.05）. After treatment，liver function indexes（DBIL，AST，ALT）in the combined traditional Chinese and Westernmedicine group was better than that in the simple operation group，the total TCM symptom score was lower than that in the simple operation group，the levels of AFP and MMP-9 were significantly lower than those in the simple operation group（P<0.05）. The levels of IL-6，CRP and TNF-αin the combined traditional Chinese and Western medicine group were lower than those in the simple operation group 7 days after surgery（P<0.05）. Sixmonths after operation，the recurrence rate of both groupswas not significant（P>0.05）. One year after the operation，the recurrence rate of the combined traditional Chinese and Westernmedicine group was lower than that of the simple operation group（P<0.05）.
Diwu Yanggan Prescription combined with laparoscopic hepatectomy has good efficacy in the treatment of primary liver cancer，with improved symptoms and liver function，good postoperative recovery，light pain，rapid recovery，fewer complications，safety and reliability，and can better prevent the tumor recurrence after 1 year，which isworthy of application.
The term“Xiwang”first appeared in The Inner Canon of Yellow Emperor and is a symptom of memory impairment. The formation mechanism of this symptom has been discussed in The Inner Canon of Yellow Emperor too. With the continuous understanding of later generations of doctors，the disease name“forgetfulness”gradually appeared，and initially recognized the relationship between emotions and memory. Inmodernmedicine，brain diseases are often accompanied by“forgetfulness”. Emotion is the source and product of human mental activities，which can affect thememory function of human brain and even lead to dementia. At the same time，as the intermediary between the five Zang-organs and mental activities，emotions affect each other，so it can be used as a therapeutic means and method to promote the recovery of memory function from the perspective of regulating Zang-Fu organs. Therefore，from the understanding of memory in traditional Chinese medicine，the relationship between emotions and memory，discussing the relationship and treatment between emotions and“forgetfulness”by focusing on single emotion and interwoven emotion.
To evaluate the impact of Yougui Pill（右归丸）and Modified Ditan Decoction（涤痰汤）on endocrine hormone metabolism and insulin resistance in the treatment of polycystic ovary syndrome（PCOS）.
A total of 102 patients with PCOSadmitted to the hospital from March 2020 to March 2024 were selected as the study objects，51 cases in the control group were treated with Western medicine alone，and a total of 51 patients in the observation group received treatment with Yougui Pill and Modified Ditan Decoction based on the standard therapy，and the clinical effects，sex hormone indexes，ovarian and menstrual conditions，and glucose metabolism indexes of the two groups were compared.
The total effective rate of the observation group was 98.04%，higher than 78.43% of the control group，and the difference was significant（P<0.05）. After treatment，the serum levels of testosterone（T）and luteinizing hormone（LH）in the two groups were lower than those before treatment，and the levels of estradiol（E2），prolactin（PRL），follicle-stimulating hormone（FSH）and sex hormone binding globulin（SHBG）were higher than those before treatment（P<0.05），and the decrease/increase in the observation group was more significant than that in the controlgroup（P<0.05）. After treatment，the ovarian volume and follicle number of the two groupswere increased（P<0.05），and the increase was more significant in the observation group compared with that in the control group（P<0.05）. The recovery rate of menstruation in the observation group was96.08%，which was higher than that（74.51%）in control group（P<0.05）. The ovarian recovery rate of the observation group was 96.08%，higher than that of the control group（76.47%，P<0.05）. After treatment，the levels of fasting blood glucose（FBG），fasting insulin（FINS），2-hour blood glucose（2 h PG）and insulin resistance index（HOMA-IR）in both groups were decreased（P<0.05）. Compared with those in the control group，the levels of FBG，FINS，2 h PG and HOMA-IR in the observation group were significantly decreased（P<0.05）.
In patients with PCOS，the combined treatment with medication and the approach of warming kidney and resolving phlegm demonstrates the significant therapeutic efficacy. This regimen effectively regulates the endocrine hormone levels，improves the glucose metabolism parameters and facilitates the recovery of the patients.
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