To observe the effect of Yinzhihuang Granules（茵栀黄颗粒）combined with ursodeoxycholic acid on the efficacy and liver function of patients with chronic jaundice hepatitis B.

A totalof132 patientswith chronic jaundice hepatitis B were enrolled in the hospital and random ly divided into observation group and control group according to the random number table method，with 66 cases in each group.The control group was treated with ursodeoxycholic acid，and the observation group was treated with Yinzhihuang Granules combined with ursodeoxycholic acid.The clinical efficacy，liver function，traditional Chinese medicine syndrome score，hepatitis B virus deoxyribonucleic acid（HBV DNA）negative conversion rate and occurrence of adverse reactions were observed in the two groups before and after treatment.

After treatment，the total effective rate of the observation group was 89.39%，which was significantly higher than that of the control group（74.24%）（P<0.05）.The liver functions of the two groups were alanine aminotransferase（ALT），aspartate aminotransferase（AST），total bilirubin（TBIL），total bile acids（TBA）andγ-glutamyl transferase（GGT）were all lower than those before treatment（P<0.05），while observing the liver function indicators of the observation group were significantly lower than those of the control group（P<0.05）.The TCM syndrome scores of the two groups were significantly lower than those before treatment（P<0.05）.At the same time，the TCM syndrome scores of the observation group were significantly lower than those of the controlgroup（P<0.05）.The HBV DNA negative conversion rate in the observation group was 56.06%，and that in the control group was 28.79%.The negative conversion rate in the observation group was significantly higher than that in the control group（P<0.05）.The incidence of liver injury in the observation group was 1.52%，which was significantly lower than that（13.64%）in the control group（P<0.05）.The incidence of adverse reactions in the observation group was 3.03%，which was not significant compared with that（10.61%）in the control group（P>0.05）.

Yinzhihuang Granules combined with ursodeoxycholic acid has a significant effect on patientswith chronic jaundice hepatitis B.It can effectively improve the clinical symptoms and liver function of patients，promote the HBV DNA negative conversion rate，and reduce the incidence of adverse reactions.

To study the clinical study of Jingu Tongxiao Pill（筋骨痛消丸）combined with arthroscopy in the treatment of knee osteoarthritis（cold coagulation blood stasis syndrome）.

A total of 120 patients diagnosed as knee osteoarthritis（cold coagulation and blood stasis syndrome）were selected and divided into two groups according to random number table.The reference group（60 cases）received arthroscopic treatment，and the study group（60 cases）received Jingu Tongxiao Pill and arthroscopic treatment.The clinical efficacy，TCM syndrome score，osteoarthritis index，inflammatory factor level and oxidative stress reaction of the two groupswere observed and compared.

Compared with that（75.00%）of the reference group，the total effective rate of the study group was98.33%，and the difference was statistically significant（P<0.05）.After treatment，the TCM syndrome score of the study group was lower than that of the reference group，and the difference was statistically significant（P<0.05）.After treatment，compared with those of the reference group，the pain，stiffness and difficulty scores of daily activities in the study group were lower，and the difference was statistically significant（P<0.05）.After treatment，compared with those of the reference group，the levels of tumor necrosis factor-alpha（TNF-α），interleukin-1 beta（IL-1β）and matrixmetalloproteinase-3（MMP-3）in the study group were lower，and the difference was statistically significant（P<0.05）.

The patients with knee osteoarthritis（cold coagulation blood stasis syndrome）were treated with arthroscopy and Jingu Tongxiao Pill，and the therapeutic effect was good，which could effectively improve the clinical symptoms and promote the recovery of patients，and the clinical application value was high.

To observe the clinical efficacy of Wangbi Capsule（尪痹胶囊）in the treatment of dampness-heat blocking collateral type of rheumatoid arthritis and its effects on serum granulocyte-macrophage colony-stimulating factor（GM-CSF），tumor necrosis factor-α（TNF-α）and CD4⁺T cell subsets.

Ninety-eighty patients with rheumatoid arthritis treated in the Rheumatology and Immunology Department of the hospital from June 2020 to June 2023 were selected as the study objects，and the above patients were divided into control group and observation group with 49 cases in each group by random number table method.The control group was given leflunomide orally，and the observation group was given Wangbi Capsule on the basis of the control group.The clinical efficacy，TCM syndrome score and adverse reactions，the degree of joint pain and the levels of serum inflammatory factors before and after treatment were compared between two groups.

The effective rate of the control group was 79.59%，and that of the observation group was 93.88%.Compared with that of the control group，the effective rate of the observation group was significantly increased（P<0.05）.There was no significant difference in TCM syndrome scores between the two groups before treatment（P>0.05）.After treatment，the levels of morning stiffness，joint flexion and extension，fever，joint swelling pain and heat in the observation group were significantly decreased compared with those in the control group（P<0.01）.Before intervention，there was no significant difference in ultrasound scores between the two groups（P>0.05）.After the intervention，the ultrasound scores in the observation group were significantly higher than those in the control group（P<0.05）.Before intervention，there was no significant difference in the degree of joint pain between the two groups（P>0.05）.Compared with those of the control group，visual analog scale（VAS）score and disease activity score 28（DAS28）score of the observation group were significantly decreased after treatment（P<0.01）.There was no significant difference in serum inflammatory factors between the two groups before intervention（P>0.05）.After the intervention，the levels of erythrocyte sedimentation rate（ESR），C-reactive protein（CRP），rheumatoid factor（RF），GM-CSF and TNF-αin the observation group were significantly decreased compared with those in the control group（P<0.01）.During the intervention，the main adverse reactions of all patients were gastrointestinal discomfort，hemocytopenia，elevated aminotransferase and skin allergy，and there was no significant difference in the incidence of adverse reactions between the two groups（P>0.05）.

Wangbi Capsule combined with leflunomide has a good clinical effect in the treatment of moisture-heat blocking collateral type of rheumatoid arthritis，which can alleviate the joint pain and dysfunction，improve the jointultrasound status and inhibit the inflammation，without increasing the adverse reactions.

To investigate the effectiveness of acupuncture at scalp acupoint penetration acupuncture combined with warming needle moxibustion in improving cognitive function and quality of life in patients with vascular dementia（VD）.

A total of124 patients with Qistagnation and blood stasis type of VD admitted to the hospital between August2017 and July 2019 were selected and divided into the needle therapy group（scalp acupoint penetration acupuncture combined with warming needle moxibustion）and the drug group（butylphthalide soft capsule），62 each in each.Both groups were treated for a total of6 weeks.The clinicalefficacy，traditional Chinese medicine syndrome scores，mini-mental state examination（MMSE），Hasegawa dementia status scale（HDS-R），functional activity questionnaire for social functioning（FAQ），activities of daily living（ADL）and adverse effects occurrence results were observed and recorded for comparison.

The total efficiency of the needle therapy group（82.26%）was significantly higher than thatof the drug group（61.29%）（P<0.05）.Before treatment，the differences in traditional Chinese medicine syndrome scores，the scores of MMSE，HDS-R，FAQ and ADL between the needle therapy group and the drug group were notstatistically significant（P>0.05）.After treatment，the traditional Chinese medicine syndrome scores and FAQ scores were significantly lower（P<0.05），and the scores of MMSE，HDS-R and ADL were significantly higher（P<0.05），and the traditional Chinese medicine syndrome scores and FAQ scores in the needle therapy group were significantly lower than those in the drug group（P<0.05），and the scores of MMSE，HDS-R and ADL in the needle therapy group were significantly greater than those in the drug group（P<0.05）.The differences in the incidence of the total adverse reactions between the needle therapy group and the drug group were not statistically significant（P>0.05）.

The efficacy of scalp acupoint penetration acupuncture combined with warming needle moxibustion in treating VD can effectively improve the patients'cognitive function and quality of life，with good safety，which is worthy of clinical promotion and application.

To observe the clinical efficacy of Qingre Jiedu Decoction（清热解毒汤）in the treatment of severe psoriasis vulgaris（blood-heat type）and its impacton serum inflammation and immune function in patients.

A prospective study was conducted on 100 patients with psoriasis vulgaris who received treatment at Shengli Oilfield Central Hospital in Dongying City.They were divided into a control group and an observation group in the order of admission，with 50 patients in each group.The control group received conventional Western medicine treatment，while the observation group received oral administration with Qingre Jiedu Decoction for 8 weeks.The total effective rate，traditional Chinese medicine syndrome scores，serum inflammation level，immune function and adverse reactions between two groups were compared.

The total effective rate of the observation group（96.00%）was significantly better than that（84.00%）of the control group，and the difference was statistically significant（P<0.05）.Before intervention，there was no significant difference in skin lesions and quality of life scores between the two groups（P>0.05）.After8 weeks of intervention，compared with those of the controlgroup，the psoriasis area and severity index（PASI）and dermatology life quality index（DLQI）of the observation group were significantly reduced（P<0.01）.The scores of symptoms such as rash color，burning sensation，itching and irritability in the observation group significantly decreased（P<0.01）.There was no significant difference in serum inflammation or T lymphocyte subsets levels between the two groups before intervention.After 8 weeks of intervention，the levels of serum tumor necrosis factor-α（TNF-α），transforming growth factor-β（TGF-β）and interleukin-6（IL-6）of the observation group were significantly down-regulated compared to those of the control group（P<0.01）.The levels of CD3⁺，CD4⁺and CD4⁺/CD8⁺in the observation group were significantly increased compared to those in the control group，while the levels of CD8⁺were significantly decreased，with statistical significance（P<0.01，P<0.05）.The incidence of adverse reactions in the observation group（16.00%）showed no significant difference compared to that（10.00%）in the control group（P>0.05）.

The combination of Qingre Jiedu Decoction（Psoriasis External Wash No.1 Formula）and Avia Capsules can improve the clinical efficacy in patients with severe psoriasis vulgaris，further improve the clinical symptoms，enhance the quality of life and significantly reduce PASI，and the mechanism of action is related to inhibiting the body's inflammatory response and regulating immune function.

To explore the effect of Qili Qiangxin Capsule（芪苈强心胶囊）on chronic heart failure and its influence on the levels of troponin（cTNI），homocysteine（Hcy），N-terminal B-type natriuretic peptide（NT-proBNP）and highsensitivity C-reactive protein（hs-CRP）in patients.

Ninety-two patients with chronic heart failure were selected and divided into control group and comprehensive group，46 cases in each group.The conventional comprehensive treatment was given，and the comprehensive group was treated with Qili Qiangxin Capsule for 3 months.The therapeutic effect，TCM syndrome scores，cardiac function and the changes of serum levels of cTNI，Hcy，NT-proBNP and hs-CRPwere observed.

There was no significant difference between the two groups in TCM syndrome scores before treatment（P>0.05），but the score decreased after treatment（P<0.05），and the score of the comprehensive group was lower than that of the control group（P<0.05）.There was no significant difference of stroke volume（SV），left ventricular end diastolic diameter（LVEDD），left ventricular ejection fraction（LVEF）or 6-minute walking test distance（6MWT）between the two groups before treatment（P>0.05），but the values of SV，LVEF and 6MWT increased after treatment（P<0.05），and these indexes of the comprehensive group were higher than those of the control group（P<0.05）.The levels of serum cTNI，Hcy，NT-proBNP and hs-CRP in the two groups were not statistically different before treatment（P>0.05），but decreased after treatment（P<0.05），and the levels of the comprehensive group were lower than those of the control group（P<0.05）.The overall curative effect of the comprehensive group was better than that of the control group（P<0.05）.

The treatment of chronic heart failure with QiliQiangxin Capsule is helpful to reduce the serum levels of cTNI，Hcy，NT-proBNP and hs-CRP，improve the symptoms and cardiac function of patients，and then improve the therapeutic effect.

To observe the clinical effect of Viral Flu Prescription combined with external treatment by pressing needle in the treatment of acute viral upper respiratory tract infection.

This study included 200 patients with acute viral upper respiratory tract infection（admitted to the emergency department and fever clinic from October 2023 to March 2024），who were divided into observation group and control group by random number tablemethod.The control group（100 cases）received conventional treatment.The observation group（100 cases）were treated with Viral Flu Prescription and external treatment by pressing needle on the basis of the control group.The data of patients in each group was compared，including the treatmenteffect，the time of body temperature returned to be normal，the time of cough，sore throat and runny nose to disappear，adverse reactions and TCM symptom scores before and after treatment（fever，sore throat，drymouth，thirst，stream turbidity stuff，etc.）and the levels of serum amyloid A（SAA），tumor necrosis factor-α（TNF-α），interleukin-6（IL-6），interleukin-10（IL-10）and other inflammatory factors.

The total effective rate of the observation group（99.00%，99/100）was higher than that of the control group（93.00%，93/100）（P<0.05）.Compared with those in the control group，the time of body temperature to return to be normal，the time for cough，sore throat and runny nose to disappear were shorter in the observation group（P<0.05）.The adverse reaction rate of the control group and the observation group was lower（P>0.05）.Before treatment，TCM symptom scores（fever，sore throat，dry and thirsty mouth，runny nose，etc.），the levels of SAA levels，TNF-α，IL-6 and IL-10 were compared in both groups（P>0.05）.After treatment，these indexes in the observation group were better than those in the control group（P<0.05）.

Viral Flu Prescription combined with external treatment by pressing needle has good clinical effect in the treatment of acute viralupper respiratory tract infection，which can better improve the symptoms of patients，promote patients to recover faster，and the treatment is safe and reliable.