To explore the effect of Qili Qiangxin Capsule(芪苈强心胶囊)on chronic heart failure and its influence on the levels of troponin(cTNI),homocysteine(Hcy),N-terminal B-type natriuretic peptide(NT-proBNP)and highsensitivity C-reactive protein(hs-CRP)in patients.
Ninety-two patients with chronic heart failure were selected and divided into control group and comprehensive group,46 cases in each group.The conventional comprehensive treatment was given,and the comprehensive group was treated with Qili Qiangxin Capsule for 3 months.The therapeutic effect,TCM syndrome scores,cardiac function and the changes of serum levels of cTNI,Hcy,NT-proBNP and hs-CRPwere observed.
There was no significant difference between the two groups in TCM syndrome scores before treatment(P>0.05),but the score decreased after treatment(P<0.05),and the score of the comprehensive group was lower than that of the control group(P<0.05).There was no significant difference of stroke volume(SV),left ventricular end diastolic diameter(LVEDD),left ventricular ejection fraction(LVEF)or 6-minute walking test distance(6MWT)between the two groups before treatment(P>0.05),but the values of SV,LVEF and 6MWT increased after treatment(P<0.05),and these indexes of the comprehensive group were higher than those of the control group(P<0.05).The levels of serum cTNI,Hcy,NT-proBNP and hs-CRP in the two groups were not statistically different before treatment(P>0.05),but decreased after treatment(P<0.05),and the levels of the comprehensive group were lower than those of the control group(P<0.05).The overall curative effect of the comprehensive group was better than that of the control group(P<0.05).
The treatment of chronic heart failure with QiliQiangxin Capsule is helpful to reduce the serum levels of cTNI,Hcy,NT-proBNP and hs-CRP,improve the symptoms and cardiac function of patients,and then improve the therapeutic effect.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |