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Effect of Qili Qiangxin Capsule(芪苈强心胶囊)on Chronic Heart Failure and Its Influence on Levels of cTNI,Hcy,NT-proBNP and hs-CRP
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Hongxia DONG1, Xiaohua GAO1, Xiaoyue LI2, Baodong LIU3, Guangming LIU1
Chinese Archives of Traditional Chinese Medicine | 2025, 43(12) : 149 - 152
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Chinese Archives of Traditional Chinese Medicine | 2025, 43(12): 149-152
Target on National Project
Effect of Qili Qiangxin Capsule(芪苈强心胶囊)on Chronic Heart Failure and Its Influence on Levels of cTNI,Hcy,NT-proBNP and hs-CRP
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Hongxia DONG1, Xiaohua GAO1, Xiaoyue LI2, Baodong LIU3, Guangming LIU1
Affiliations
  • 1.Heping Hospital Affiliated to ChangzhiMedical College,Changzhi046000,Shanxi,China
  • 2.Changzhi Second People's Hospital,Changzhi046099,Shanxi,China
  • 3.Luzhou District People's Hospital,Changzhi046011,Shanxi,China
Published: 2025-12-10 doi: 10.13193/j.issn.1673-7717.2025.12.026
Outline
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Objective

To explore the effect of Qili Qiangxin Capsule(芪苈强心胶囊)on chronic heart failure and its influence on the levels of troponin(cTNI),homocysteine(Hcy),N-terminal B-type natriuretic peptide(NT-proBNP)and highsensitivity C-reactive protein(hs-CRP)in patients.

Methods

Ninety-two patients with chronic heart failure were selected and divided into control group and comprehensive group,46 cases in each group.The conventional comprehensive treatment was given,and the comprehensive group was treated with Qili Qiangxin Capsule for 3 months.The therapeutic effect,TCM syndrome scores,cardiac function and the changes of serum levels of cTNI,Hcy,NT-proBNP and hs-CRPwere observed.

Results

There was no significant difference between the two groups in TCM syndrome scores before treatment(P>0.05),but the score decreased after treatment(P<0.05),and the score of the comprehensive group was lower than that of the control group(P<0.05).There was no significant difference of stroke volume(SV),left ventricular end diastolic diameter(LVEDD),left ventricular ejection fraction(LVEF)or 6-minute walking test distance(6MWT)between the two groups before treatment(P>0.05),but the values of SV,LVEF and 6MWT increased after treatment(P<0.05),and these indexes of the comprehensive group were higher than those of the control group(P<0.05).The levels of serum cTNI,Hcy,NT-proBNP and hs-CRP in the two groups were not statistically different before treatment(P>0.05),but decreased after treatment(P<0.05),and the levels of the comprehensive group were lower than those of the control group(P<0.05).The overall curative effect of the comprehensive group was better than that of the control group(P<0.05).

Conclusion

The treatment of chronic heart failure with QiliQiangxin Capsule is helpful to reduce the serum levels of cTNI,Hcy,NT-proBNP and hs-CRP,improve the symptoms and cardiac function of patients,and then improve the therapeutic effect.

Qili Qiangxin Capsule(芪苈强心胶囊)  /  chronic heart failure  /  troponin  /  Hcy  /  NT-proBNP  /  hs-CRP  /  effect
Hongxia DONG, Xiaohua GAO, Xiaoyue LI, Baodong LIU, Guangming LIU. Effect of Qili Qiangxin Capsule(芪苈强心胶囊)on Chronic Heart Failure and Its Influence on Levels of cTNI,Hcy,NT-proBNP and hs-CRP[J]. Chinese Archives of Traditional Chinese Medicine, 2025 , 43 (12) : 149 -152 . DOI: 10.13193/j.issn.1673-7717.2025.12.026
Year 2025 volume 43 Issue 12
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doi: 10.13193/j.issn.1673-7717.2025.12.026
  • Online Date:2026-04-29
  • Published:2025-12-10
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    1.Heping Hospital Affiliated to ChangzhiMedical College,Changzhi046000,Shanxi,China
    2.Changzhi Second People's Hospital,Changzhi046099,Shanxi,China
    3.Luzhou District People's Hospital,Changzhi046011,Shanxi,China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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