To investigate the clinical value of Tongfu Xingshen Decoction（通腑醒神汤）Combined with Western Medicine treatment of hypertensive intracerebral hemorrhage.

A hundred patients with hypertensive intracerebral hemorrhage，they were randomly divide into the control group and the observation group，50 cases in each group.Both groups were treated with conventional Western medicine，while the observation group was treated with Tongfu Xingshen Decoction as an auxiliary treatment on the basis of the control group，with treatment course of 4 weeks.The changes of traditional Chinese medicine syndrome scores，neurological and cognitive functions，serum brain injury and free radical indicators，and the levels of anti-inflammatory factors were observed before and after treatment.

There was no statistically significant difference in the scores of traditional Chinese medicine symptoms between the two groups before treatment（P>0.05）.The scores decreased after treatment（P<0.05），and the degree of decline in the observation group was greater than that in the control group（P<0.05）.There was no statistically significant difference in the scores of Glasgow Coma Scale（GCS），the National Institutes of Health Stroke Scale（NIHSS），Mini-mental State Examiniation（MMSE）or Montreal Cognitive Assessment（MoCA）between the two groups before treatment（P>0.05）.The scores of GCS，MMSE and MoCA increased after treatment（P<0.05），and the degree of increase in the observation group was greater than that in the control group（P<0.05）.The NIHSSscores decreased after treatment（P<0.05），and the degree of decline in the observation group was greater than that in the control group（P<0.05）.There was no statistically significant difference in the serum neuron specific enolase（NSE）or astrocyte derived protein（S100β）between the two groups before treatment（P>0.05）.They were decreased after treatment（P<0.05），and the degree of decline in the observation group was greater than that in the control group（P<0.05）.There was no statistically significant difference in the serum superoxide dismutase（SOD），malondialdehyde（MDA），endothelin-1（NT-1）or nitric oxide（NO）between the two groups before treatment（P>0.05）.The levels of MDA and NT-1 were decreased after treatment（P<0.05），and the degree of decline in the observation group was greater than that in the control group（P<0.05）.The levels of SOD and NO increased after treatment（P<0.05），and the degree of increase in the observation group was greater than that in the control group（P<0.05）.There was no statistically significant difference in the serum interleukin-6（IL-6）and tumor necrosis factor-α（TNF-α）between the two groups before treatment（P>0.05）.They were decreased after treatment（P<0.05），and the degree of decline in the observation group was greater than that in the control group（P<0.05）.

Tongfu Xingshen Decoction in assisting the treatment of hypertensive intracerebral hemorrhage can significantly improve clinical symptoms，neurological function and cognitive function of patients，and its effect may be related to inhibiting brain damage caused by inflammatory mediators and free radicals.

To study the clinical efficacy of Ginkgolide Dispersible Tablets combined with hyperbaric oxygen in the treatment of acute cerebral infarction（ACI）.

A total of 326 patients with ACIwho were treated in the hospital from April 2019 to October 2022 were selected as the study subjects.They were divided into treatment group（163 cases）and control group（163 cases）according to different intervention methods.Both groups received symptomatic treatment such as oxygen inhalation，blood pressure reduction and lipid regulation，and anti-platelet aggregation.On this basis，the treatment group was treated with Ginkgolide Dispersible Tablets and hyperbaric oxygen，while the control group was only treated with hyperbaric oxygen，and the patients in both groups were treated continuously for 2 weeks.The levels of carotid atherosclerosis indicators［carotid intimamedia thickness（IMT），carotid plaque area］，NF-κB signaling pathway-related factors（NF-κB p50，p65 mRNA and protein），and downstream inflammatory factors［interleukin-8（IL-8），interleukin-1β（IL-1β），tumor necrosis factor-alpha（TNF-α）］were measured before and after treatment.Simultaneously，Barthel Index（BI）scores，National Institutes of Health Stroke Scale（NIHSS）scores，traditional Chinese medicine syndrome scores were assessed.Additionally，the clinical efficacy was evaluated after the course of treatment and the drug-related adverse events during the trial period were recorded.

After treatment，the total effective rate of the treatment group was 95.71%，higher than that of the control group（84.66%）.There was a significant difference between the two groups（P<0.05），but there was no significant difference in adverse events between the two groups（P>0.05）.At the same time，the BI scores of the two groups were significantly higher after treatment，and BI score of the treatment group was higher than that of the control group（P<0.05）.The NIHSS score，traditional Chinese medicine syndrome points，IMT，plaque area and the levels of TNF-α，IL-8，IL-1β，NF-κB p50，p65 mRNA and protein were significantly lower in the treatment group than those in the control group（P<0.05）.

Ginkgolide Dispersible Tablets combined with hyperbaric oxygen can significantly inhibit the activation of NF-κB inflammatory signal pathway in patients with ACI and improve its inflammatory damage status，further stabilizing the atherosclerotic plaque，significantly improving the clinical efficacy，with less adverse reactions.And at the same time，it is conducive to the optimization of neurological function and quality of prognosis.

To study the effect of Yiqi Yangyin Quyu Decoction（益气养阴祛瘀汤）on parotid radionuclide dynamic imaging index and immune function in patients with Sjogren's syndrome.

Eighty-four patients with Sjogren's syndrome treated in the hospital from January 2022 to January 2023 were selected and randomly divided into two groups according to the random number table method，with 42 cases in each group.The patients in the control group were treated with conventional western medicine and those in the observation group were treated with Yiqi Yangyin Quyu Decoction on the basis of the control group.The treatment course of the two groups was3 months.The quantitative scores of TCM symptoms，changes in disease activity［Sjgren's syndrome disease activity index（ESSDAI）and EULAR Sjgren's syndrome patient reporting index（ESSPRI）］，parotid radionuclide dynamic imaging indicators［uptake fraction（IF），excretion fraction（EF）］，immune function indicators［erythrocyte sedimentation rate（ESR），C-reactive protein（CRP），immunoglobulin G（IgG），anti-Sjgren's syndrome antigen A（SSA）antibody，anti-Sjögren's syndrome antigen B（SSB）antibody］and adverse reactions were compared between the two groups.

Before treatment，there was no significant difference in the observation indexes between the two groups（P>0.05）.After treatment，the scores of TCM symptoms such as red tongue and less body fluid，no coating/less coating/peeling，dry mouth and desire to drink，dry eyes and less tears in the observation group were significantly lower than those in the control group［（1.72±0.53）points，（1.96±0.70）points，（2.03±0.91）points，（1.70±0.84）points vs（1.98±0.61）points，（2.36±0.59）points，（2.89±0.72）points，（2.13±0.77）points］（P<0.05）.The ESSDAI and EULAR scores of the observation group were significantly higher than those of the control group［（5.92±1.60）points，（4.36±1.02）points vs（6.87±1.54）points，（5.39±0.96）points］（P<0.05）.The levels of IF and EF of parotid radionuclide dynamic imaging were significantly higher than those of the control group［（1.87±0.26）%，（21.07±4.20）% vs（1.74±0.19）%，（17.96±3.75）%］.The immune function indexes（ESR，IgG，positive rate of anti-SSA antibody and positive rate of anti-SSB antibody）were significantly better than those of the control group［（19.83±1.84）mm/h，（6.90±1.37）g/L，（41.28±5.69）%，（28.91±4.03）% vs（21.05±1.69）mm/h，（8.81±1.19）g/L，（53.47±5.18）%，（6.28±3.71）%］（P<0.05）.There was no significant difference in the incidence of adverse reactions between the observation group（7.14%）and the control group（11.90%）（P>0.05）.

Yiqi Yangyin Quyu Decoction is effective in the treatment of Sjogren's syndrome.It can relieve the symptoms of patients more effectively，improve the body's immune function and parotid radionuclide dynamic imaging indicators.It is safe and reliable，and has application value.

To study the effects of Yiqi Huoxue Fuyuan Decoction（益气活血复元汤）combined with minimally invasive surgery on bone metabolism and bone healing of calcaneal fracture.

Eighty patients diagnosed as calcaneal fracture were selected and divided into two groups according to random number table.Forty patients in the reference group were treated with minimally invasive surgery，and forty patients in the study group were treated with Yiqi Huoxue Fuyuan Decoction combined with minimally invasive surgery.The clinical efficacy，TCM syndrome score，bone metabolism index，bone healing index and imaging index of the two groups were observed and compared.

Compared with that（77.50%）of the reference group，the total effective rate of the study group was97.50%，and the difference was statistically significant（P<0.05）.Compared with that of the reference group，the TCM syndrome score of the study group was lower，and the difference was statistically significant（P<0.05）.Compared with those of the reference group，the levels of osteocalcin（OC）and bone alkaline phosphatase（BALP）in the study group were higher，and the levels of pyridinoline（PYD）and tartrate resistant acid phosphatase（TRAP）were lower，with statistical significance（P<0.05）.Compared with those of the reference group，the levels of alkaline phosphatase（ALP），propeptide of typeⅠprocollagen（PICP），insulin-like growth factor（IGF）and bone morphogenetic protein（BMP）in the study group were higher，and the differences were statistically significant（P<0.05）.Compared with those of the reference group，Bohler Angle，Gissane Angle and calcaneus height in the study group were higher，and calcaneus width was lower，with statistical significance（P<0.05）.

The combination of minimally invasive surgery and Yiqi Huoxue Fuyuan Decoction can effectively improve the clinical symptoms of patients with calcaneal fracture and promote fracture healing，with high clinical application value.

To study the effect of TCM constitution types on stress response of general anesthesia combined with epidural block in elderly patients with cervical cancer undergoing laparoscopic hysterectomy.

A total of 420 elderly patients with cervical cancer admitted to the hospital from January 2021 to December 2022 were selected.The laparoscopic hysterectomy was successfully completed under general anesthesia combined with epidural block，and there were 140 cases of mild constitution，140 cases of Yin deficiency constitution and 140 cases of Yang deficiency constitution.The anesthesia conditions of patients with different constitution types，vital signs and stress response at 5 min before anesthesia，30 min after anesthesia and 6 h after operation were compared.The anesthesia conditions included remifentanil dosage，propofol dosage，anesthesia induction time，recovery time，vital signs indexes included body temperature，heart rate，respiratory rate）and stress response indexes included norepinephrine，epinephrine and cortisol.

There was no significant difference in remifentanil dosage，propofol dosage or anesthesia induction time among the three groups（P>0.05）.The recovery time of patients with mild constitution was shorter（P<0.05）.There was no significant difference in body temperature，respiratory rate and heart rate among the three groups at 5 min before an-esthesia（P>0.05）.The body temperature，respiratory rate and heart rate of the three groups decreased at 30 min after anesthesia，and returned to be normal at 6 h after operation.There was no significant difference among the three groups（P>0.05）.The above indexes of the three groups were significantly increased at 30 min after anesthesia，and significantly decreased at 6 h after operation.The levels of norepinephrine，epinephrine and cortisol in patients with mild constitution were significantly better than those in patients with Yin deficiency constitution and Yang deficiency constitution at 30 min after anesthesia and 6 h after operation（P<0.05）.

The elderly patients with cervical cancer with gentle constitution can better regulate the stress response of general anesthesia combined with epidural block in laparoscopic hysterectomy，which is beneficial to the postoperative rehabilitation of patients.

To explore the effect of Xiaojia Decoction（消瘕汤）combined with denogestrin on sexual hormone levels and ovarian function in patients with adenomyosis.

Ninety patients with kidney deficiency and blood stasis type of adenomyosis who were treated in the hospital from January 2021 to December 2022 were collected and randomly divided into A group and B group，with 45 patients in each group.Group A was treated with dinoprotein，while Group B was treated with Xiaojia Decoction combined with dinoprotein.The treatment effects，traditional Chinese medicine symptom scores，sex hormone levels and serum indicators were compared between the two groups.

The effective rate of treatment in Group B was significantly higher than that in Group A（P<0.05）.After treatment，the scores of menstrual cycle，menstrual volume，menstrual abdominal pain，mental depression，chest and flank fullness and tongue purple dark in Group B were significantly lower than those before treatment（P<0.05），and the scores of Group B were significantly lower than those of Group A（P<0.05）.After treatment，the levels of testosterone（T），follicle stimulating hormone（FSH）and luteinizing hormone（LH）in Group B were significantly lower than those before treatment（P<0.05），and the levels of Group B were significantly lower than those of Group A（P<0.05）.The level of estradiol（E₂）was significantly higher than that before treatment（P<0.05），and the level of Group B was significantly higher than that of Group A（P<0.05）.After treatment，the levels of matrix metalloproteinase-9（MMP-9），vascular endothelial growth factor（VEGF）and matrix metalloproteinase-2（MMP-2）in Group B were significantly lower than those before treatment（P<0.05），and the levels of group B were significantly lower than those of Group A（P<0.05）.

The combina-tion of Xiaojia Decoction and dinoregestone has good clinical efficacy in treating patients with adenomyosis，which is beneficial for slowing down the progression of adenomyosis，regulating the levels of sexual hormones in patients，improving ovarian function and effectively alleviating clinical symptoms.

To investigate the effects of Qishen Yiqi Dropping Pills（芪参益气滴丸）combined with non-invasive positive pressure ventilation on clinical symptoms，cardiac function and oxidative stress in patients with acute heart failure（AHF）.

A total of 110 patients with acute heart failure admitted to the hospital from November 2017 to November 2022 were selected as study subjects.According to different treatment methods，they were divided into study group and control group，55 cases in each group.Both groups received conventional western medicine treatment plus non-invasive positive pressure ventilation.The study group combined with Qishen Yiqi Dripping Pills.The changes of physical signs，clinical efficacy，cardiac function indexes（EF），B-type brain natriuretic peptide precursor（NT-probNP）and oxidative stress indexes［serum superoxide dismutase（SOD），glutathione peroxidase（GSH-Px），malondialdehyde（MAD）］were compared between the two groups.

24 h after treatment，the values of heart rate（HR），respiratory rate（RR），mean arterial pressure（MAP）and oxygenation index（PO₂/FiO₂）in both groups were significantly improved compared with those before treatment（P<0.05），and the improvement degree of all indexes in the study group was significantly higher than that in the control group（P<0.05）.The total effective rate of the study group was significantly higher than that of the control group（P<0.05）.In the study group，4 cases were ineffective，3 cases were improved and 1 case died after endotracheal intubation and invasive ventilation.In the control group，12 cases were ineffective，8 cases were improved and 4 cases died after endotracheal intubation and invasive ventilation.After 3 d treatment，the levels of EF and NT-probNP in both groups were significantly improved compared with those before treatment（P<0.05），and the improvement degree in the study group was significantly higher than that in the control group（P<0.05）.After 3 d treatment，the levels of SOD，GSH-Px and MAD in both groups were significantly improved compared with before treatment（P<0.05），and the improvement in the study group was significantly higher than that in the control group（P<0.05）.Serious adverse reactions occurred in both groups during treatment.

Qishen Yiqi Dropping Pills combined with non-invasive positive pressure ventilation can significantly improve the therapeutic effect of acute heart failure，and has significant effects on improving clinical symptoms，cardiac function and oxidative stress of patients，and has a high safety，suitable for promotion.