To investigate the clinical value of Tongfu Xingshen Decoction（通腑醒神汤）Combined with Western Medicine treatment of hypertensive intracerebral hemorrhage.

A hundred patients with hypertensive intracerebral hemorrhage，they were randomly divide into the control group and the observation group，50 cases in each group.Both groups were treated with conventional Western medicine，while the observation group was treated with Tongfu Xingshen Decoction as an auxiliary treatment on the basis of the control group，with treatment course of 4 weeks.The changes of traditional Chinese medicine syndrome scores，neurological and cognitive functions，serum brain injury and free radical indicators，and the levels of anti-inflammatory factors were observed before and after treatment.

There was no statistically significant difference in the scores of traditional Chinese medicine symptoms between the two groups before treatment（P>0.05）.The scores decreased after treatment（P<0.05），and the degree of decline in the observation group was greater than that in the control group（P<0.05）.There was no statistically significant difference in the scores of Glasgow Coma Scale（GCS），the National Institutes of Health Stroke Scale（NIHSS），Mini-mental State Examiniation（MMSE）or Montreal Cognitive Assessment（MoCA）between the two groups before treatment（P>0.05）.The scores of GCS，MMSE and MoCA increased after treatment（P<0.05），and the degree of increase in the observation group was greater than that in the control group（P<0.05）.The NIHSSscores decreased after treatment（P<0.05），and the degree of decline in the observation group was greater than that in the control group（P<0.05）.There was no statistically significant difference in the serum neuron specific enolase（NSE）or astrocyte derived protein（S100β）between the two groups before treatment（P>0.05）.They were decreased after treatment（P<0.05），and the degree of decline in the observation group was greater than that in the control group（P<0.05）.There was no statistically significant difference in the serum superoxide dismutase（SOD），malondialdehyde（MDA），endothelin-1（NT-1）or nitric oxide（NO）between the two groups before treatment（P>0.05）.The levels of MDA and NT-1 were decreased after treatment（P<0.05），and the degree of decline in the observation group was greater than that in the control group（P<0.05）.The levels of SOD and NO increased after treatment（P<0.05），and the degree of increase in the observation group was greater than that in the control group（P<0.05）.There was no statistically significant difference in the serum interleukin-6（IL-6）and tumor necrosis factor-α（TNF-α）between the two groups before treatment（P>0.05）.They were decreased after treatment（P<0.05），and the degree of decline in the observation group was greater than that in the control group（P<0.05）.

Tongfu Xingshen Decoction in assisting the treatment of hypertensive intracerebral hemorrhage can significantly improve clinical symptoms，neurological function and cognitive function of patients，and its effect may be related to inhibiting brain damage caused by inflammatory mediators and free radicals.