To improve and perfect the quality standards of rice water to ensure the stable quality of rice water processed traditional Chinese medicine decoction pieces.

The clarification and pH value of rice water were determined. Using L-lysine as the control substance，thin layer chromatography（TLC）was used to qualitatively identify the rice water. The total amino acid content and enzyme activity were determined by ultraviolet-visible spectroscopy（UV）method.

The turbidity values of the 10 batches of samples ranged from 2. 280-3. 412. The pH values of the 10 batches ranged from 6. 14-6. 58. The TLC spots were clear and repeatable. The linear range of the total amino acid was 5.31-53. 1μg（r=0.999 0），and the recoveries were 97.54%-100.1%（RSD=0.9%）. The total amino acid content was 1.19-1.47 mg·mL^-1，and the enzyme activity was 5.42-6.37 U·L^-1.

The quality control method of rice water was improved. The method is accurate，stable and reproducible，and can be used for the quality control of rice water.

To investigate the effects of Yiwei Decoction（益胃汤）and Maimendong Decoction（麦门冬汤）on the clinical prognosis and intestinal flora of patients with stomach stuffiness of spleen-stomach weakness type.

A total of 116 patients with stomach stuffiness of spleen-stomach weakness type were selected and randomly divided into control group and observation group，58 cases in each group. The control group was given quadruple therapy，and the observation group was treated with Yiwei Decoction and Maimendong Decoction on the basis of the control group for 4 weeks. Before and after the treatment，the two groups were compared in terms of clinical efficacy，traditional Chinese medicine symptom scores，serum indexes，gastrointestinal hormones，Helicobacter pylori（Hp）conversion and intestinal flora.

After treatment，the total effective rate of the observation group was 94.83%（55/58），which was significantly better than that（79.31%，46/58）of the control group（P<0.05），and the Hp clearance rate of the observation group was 96.55%（56/58），while that the control group was 86.21%（50/58）. The traditional Chinese medicine symptom scores of the patients in both groups were significantly reduced（P<0.05），and the scores of the observation group were significantly lower than those of the control group（P<0.05）. The levels of interleukin-6（IL-6），tumor necrosis factor-α（TNF-α），transforming growth factor-β1（TGF-β1）and C-reactive protein（CRP）of two groups were significantly lower than those before treatment（P<0.05），and the levels of the observation group were significantly lower than those of the control group（P<0.05）. The levels of somatostatin（SS）and epidermal growth factor（EGF）were significantly higher in both groups（P<0.05），and the levels of the observation group were significantly higher than those of the control group（P<0.05）. the level of gastrin（GAS）was significantly lower in both groups，and the level of the observation group was significantly lower than that of the control group（P<0.05）. Bifidobacterium and Lactobacillus increased in both groups compared with those in the pre-treatment period（P<0.05），and Bifidobacterium and Lactobacillus of the observation group were significantly higher than those of the control group（P<0.05）. Staphylococcus and Enterococcus decreased in both groups compared with those in the pre-treatment period（P<0.05），and Staphylococcus and Enterococcus of the observation group were significantly lower than those of the control group（P<0.05）.

The clinical efficacy of Yiwei Decoction combined with Maimendong Decoction on patients with stomach stuffiness of spleen-stomach weakness type is remarkable，which can improve the clinical symptoms，reduce the inflammatory reaction and improve the intestinal flora of patients.

To explore the clinical efficacy of Hejie Qingre Xiaoji Decoction（和解清热消积汤）on children with recurrent upper respiratory tract infection of lung-spleen Qi deficiency and heat stagnation type.

Seventy-two children with recurrent upper respiratory tract infection of lung-spleen Qi deficiency and heat stagnation type who received treatment in department of pediatrics of the hospital were selected from January 2023 to December 2023，and were divided into observation group and control group by simple randomization method，with 36 cases in each group. The control group was treated with western medicine，whereas the observation group was given Hejie Qingfei Xiaoji Decoction on the basis of the control group. The improvement degrees of clinical symptoms and adverse reactions after 1 week of treatment and TCM syndromes scores，T lymphocyte subsets［cluster of differentiation 3+（CD3⁺），cluster of differentiation 4+（CD4⁺），cluster of differentiation 8+（CD8⁺），CD4⁺/CD8⁺］，immunoglobulins［immunoglobulin A（IgA），immunoglobulin M（IgM），immunoglobulin G（IgG）］and Th₁/Th₂ immune response indicators［interleukin-2（IL-2），interferon-gamma（IFN-γ），interleukin-4（IL-4），interleukin-10（IL-10）］before treatment and after 1 week of treatment were compared between groups.

After 1 week of treatment，the improvement times of clinical symptoms，TCM syndromes scores，the levels of CD8⁺，IL-4 and IL-10 in the two groups were significantly lower than those in control group（P<0.05）while the levels of T lymphocyte subsets（CD3⁺，CD4⁺，CD4⁺/CD8⁺），immunoglobulins and Th₁/Th₂ immune response indicators（IL-2，IFN-γ）were significantly higher than those in control group（P<0.05）. There were no obvious adverse reactions in both groups.

Hejie Qingfei Xiaoji Decoction can effectively regulate the body’s immune function of children with recurrent upper respiratory tract infection of lung-spleen Qi deficiency and heat stagnation type，enhance the body’s immunity，relieve the clinical symptoms and accelerate the disease recovery process，and it has good clinical efficacy.

To study the effect of the tonifying kidney，expelling phlegm，removing blood stasis and strengthening brain method on the mental state and living ability of patients with Alzheimer's disease.

Eighty patients with Alzheimer's disease diagnosed and treated in the hospital from April 2023 to January 2024 were selected. The patients were divided into observation group and control group by single and double number method，with 40 cases in each group. The control group was treated with donepezil hydrochloride，while the observation group was treated with the method of tonifying kidney，expelling phlegm，removing blood stasis and strengthening brain combined with donepezil hydrochloride. Both groups were treated for 12 weeks. The symptoms（TCM syndrome scores），mental state［Alzheimer's Disease Assessment Scale-cognitive subscale（ADAS-Cog），Mini-Mental State Examination（MMSE），Montreal Cognitive Assessment（MoCA）］，living ability［Activity of Daily Living Scale（ADL）］，serum indicators［amyloid β-protein（Aβ），phosphorylated Tau protein（p-Tau）protein，corticotropin-releasing factor（CRF），adrenocorticotropin-releasing factor（CRF），adrenocorticotropic hormone（ACTH）and cortisol（CORT）］and adverse reactions were compared between the two groups.

After treatment，the scores of TCM syndromes of incontinence，soreness and weakness of waist and knees，tinnitus and deafness，and frequent nocturia in the observation group were significantly decreased（P<0.05），and those indexes in the observation group were lower than those in the control group（P<0.05）. After treatment，the ADAS-Cog，MMSE，MoCA scores and ADL scores of the two groups were significantly improved（P<0.05），and the results of the observation group were better than those of the control group（P<0.05）. After treatment，the levels of serum Aβ，p-Tau protein，CRF，ACTH and CORT in the two groups were significantly improved（P<0.05），and those in the observation group were better than those in the control group（P<0.05）. No serious adverse reactions occurred in both groups.

The method of tonifying kidney，expelling phlegm，removing blood stasis and strengthening brain can significantly improve the symptoms，the intellectual status and living ability in the treatment of Alzheimer's disease，and can be used as a safe and effective preferred treatment plan.

To study the effect of Danggui Dilong Guizhi Decoction（当归地龙桂枝汤）combined with acupuncture and moxibustion on cervical spondylosis pain and upper limb numbness.

A total of 128 patients with cervical spondylosis pain and upper limb numbness diagnosed and treated in the acupuncture department of the hospital from June 2021 to October 2023 were selected as the research objects and randomly divided into two groups. Sixty-four patients in the control group were treated with acupuncture and moxibustion，and the other 64 patients in the observation group were treated with Danggui Dilong Guizhi Decoction combined with acupuncture and moxibustion. The course of treatment was 4 weeks. The improvement of pain and upper limb numbness，cervical spine function，electromyography index，inflammatory factors and adverse reactions were observed and compared between the two groups.

After treatment，the scores of pain and upper limb numbness in the observation group were significantly lower than those in the control group［（0.87±0.14）points，（0.79±0.12）points vs（0.96±0.20）points，（0.88±0.17）points］（P<0.05）. The neck pain and related symptoms，activities of daily living and total scores of Neck Disability Index（NDI）in the observation group were significantly higher than those in the control group［（6.08±1.84）points，（9.74±1.69）points，（15.62±1.73）points vs（8.90±2.01）points，（10.83±2.30）points，（18.32±2.26）points］（P<0.05），The motor nerve conduction velocity（MCV）and sensory nerve conduction velocity（SCV）in the observation group were significantly higher than those in the control group［（49.22±4.30）m/s，（43.36±4.51）m/s vs（46.85±3.91）m/s，（39.40±5.48）m/s］（P<0.05），The levels of serum interleukin（IL）-8，IL-1β and tumor necrosis factor-α（TNF-α）in the observation group were significantly lower than those in the control group［（59.73±11.42）ng/L，（3.87±1.08）ng/L，（9.77±2.38）ng/L vs（65.71±12.13）ng/L，（5.27±1.20）ng/L，（11.21±2.61）ng/L］（P<0.05）. No serious adverse reactions occurred in both groups.

Danggui Dilong Guizhi Decoction combined with acupuncture has a significant effect on the treatment of cervical spondylosis pain and upper limb numbness，it can improve the symptoms of pain and upper limb numbness，enhance the cervical spine function，improve the muscle strength and reduce the inflammatory response，it is safe and worthy of application.

To analyze a short-to-medium term prospective study based on carotid ultrasound and transcranial Doppler ultrasound evaluating the combination of traditional Chinese and Western medicine in the treatment of carotid artery stenosis.

Ninety patients with a diagnosis of carotid artery stenosis and meeting the surgical criteria for carotid endarterectomy（CEA）admitted to the hospital from January 2022 to December 2023 were selected for the study. They were divided into two groups according to the randomized numerical table method. Forty-five cases of the control group were treated with carotid endarterectomy，and forty-five cases of the observation group were treated with acupuncture in combination with carotid endarterectomy. The two groups' treatment effects，TCM symptom scores of two groups were compared and carotid ultrasound and transcranial Doppler color ultrasound were used to observe the changes in cerebral hemodynamic indexes before and after surgery，and the incidence of stroke or restenosis in six months of postoperative follow-up was compared.

The total effective rate of treatment in the observation group was 95.56%（43/45），which was much higher than that（75.56%，34/45）in the control group，and the difference between the two groups was not statistically significant（P<0.05）. The TCM symptom scores of the observation group were lower than those of the control group at 8，12 and 24 weeks postoperatively，and the values of peak systolic velocity（PSV）and end diastolic velocity（EDV）were lower than those of the control group at 8，12 and 24 weeks postoperatively，and the values of MCA-PSV and MCA-PI were higher than those of the control group（P<0.05）. At 6 months of follow-up，there was no statistically significant difference in the incidence of stroke or restenosis between the two groups（P>0.05）.

- Carotid endarterectomy combined with acupuncture in the treatment of carotid artery stenosis has a clear short-to-medium term effect，which can effectively improve the patients' symptoms，reduce the thickness of the carotid intima-media and carotid plaque formation，promote the improvement of the cerebral hemodynamic indexes，and reduce the incidence of postoperative adverse events such as restenosis，which has a positive effect on the improvement of the prognosis.

To investigate the effect of Qiangxin Decoction（强心汤）combined with Yixin Huazhuo Decoction（益心化浊方）on clinical prognosis and cardiac function of chronic heart failure with Qi deficiency and blood stasis.

A total of 104 patients with chronic heart failure with Qi deficiency and blood stasis admitted to the hospital from March 2021 to January 2023 were selected as research objects. The patients were given random envelopes upon admission and divided into study group and control group with 52 cases in each group according to odd-even simple random method. The control group received conventional Western medicine treatment. Qiangxin Decoction and Yixin Huazhuo Decoction were used for 1 course of treatment（4 weeks），and both groups were treated for 2 courses of treatment. The clinical efficacy，TCM symptom scores before and after treatment，cardiac function indexes［N terminal brain natriuretic peptide（NT-pro BNP），left ventricular end-diastolic diameter（LVEDD），left ventricular end-systolic diameter（LVESD），left ventricular ejection fraction（LVEF）］，vascular endothelial cell function［endothelin-1（ET-1），nitric oxide（NO）］and adverse reactions in the two groups were compared.

The total effective rate of the study group was 80.77%（42/52），which was significantly higher than that of the control group（61.54%，32/52），with statistical significance（P<0.05）. After treatment，the scores of shortness of breath，palpitation，chest tightness，chest pain and lower limb edema were significantly lower in both groups than those before treatment（P<0.05），and those in the study group were significantly lower than those in the control group（P<0.05）. After treatment，the levels of LVEDD，LVESD and NT-proBNP in both groups were lower than those before treatment，and the levels of the study group were significantly lower than those of the control group（P<0.05）. The levels of LVEF in both groups were higher than those before treatment，and the level of LVEF of the study group was higher than that of the control group（P<0.05）. After treatment，the levels of NO in both groups were significantly higher than those before treatment，the levels of ET-1 were significantly lower than those before treatment，and the change in the study group was more obvious than that in the control group（P<0.05），and there was no significant difference in the occurrence of adverse reactions between the two groups during treatment（P>0.05）.

Qiangxin Decoction combined with Yixin Huazhuo Decoction can significantly improve the therapeutic effect and cardiac function of patients with chronic heart failure with Qi deficiency and blood stasis and has a high safety，suitable for popularization and application.

To investigate the clinical efficacy of Buzhong Yiqi Decoction（补中益气汤，BZYQT）combined with thrombopoietin receptor agonists（TPO-RA）in treating thrombocytopenia caused by tumor therapy.

A total of 160 patients with thrombocytopenia due to tumor therapy were randomly divided into a control group and an experimental group，each consisting of 80 cases. The control group was only given TPO-RA treatment，while the experimental group received BZYQT in combination with TPO-RA. After 8 weeks，the two groups were compared in terms of platelet count，bleeding risk level，Karnofsky performance status（KPS）score，changes in serum thrombopoietin（TPO）content and adverse reactions.

After treatment，both groups showed significant recovery in platelet parameters，bleeding risk，KPS score and serum TPO content. Compared with that of the control group，the overall effectiveness rate of the treatment group reached 95.00%（76/80）. Additionally，the values of platelet count（PLT）and plateletcrit（PCT）of the experimental group were higher than those of the control group（P<0.001），while the values of platelet distribution width（PDW）and mean platelet volume（MPV）were lower（P<0.001）. The improvement in bleeding risk and KPS score was more pronounced in the experimental group than that in the control group（P<0.001）. The serum TPO content in the experimental group was significantly higher than that in the control group（P<0.001），and the number of adverse reaction events decreased.

The combination of BZYQT and TPO-RA in treating thrombocytopenia caused by tumor therapy yields more significant effects and can reduce the adverse reactions caused by TPO-RA to a certain extent.