To study the effect of Danggui Dilong Guizhi Decoction（当归地龙桂枝汤）combined with acupuncture and moxibustion on cervical spondylosis pain and upper limb numbness.

A total of 128 patients with cervical spondylosis pain and upper limb numbness diagnosed and treated in the acupuncture department of the hospital from June 2021 to October 2023 were selected as the research objects and randomly divided into two groups. Sixty-four patients in the control group were treated with acupuncture and moxibustion，and the other 64 patients in the observation group were treated with Danggui Dilong Guizhi Decoction combined with acupuncture and moxibustion. The course of treatment was 4 weeks. The improvement of pain and upper limb numbness，cervical spine function，electromyography index，inflammatory factors and adverse reactions were observed and compared between the two groups.

After treatment，the scores of pain and upper limb numbness in the observation group were significantly lower than those in the control group［（0.87±0.14）points，（0.79±0.12）points vs（0.96±0.20）points，（0.88±0.17）points］（P<0.05）. The neck pain and related symptoms，activities of daily living and total scores of Neck Disability Index（NDI）in the observation group were significantly higher than those in the control group［（6.08±1.84）points，（9.74±1.69）points，（15.62±1.73）points vs（8.90±2.01）points，（10.83±2.30）points，（18.32±2.26）points］（P<0.05），The motor nerve conduction velocity（MCV）and sensory nerve conduction velocity（SCV）in the observation group were significantly higher than those in the control group［（49.22±4.30）m/s，（43.36±4.51）m/s vs（46.85±3.91）m/s，（39.40±5.48）m/s］（P<0.05），The levels of serum interleukin（IL）-8，IL-1β and tumor necrosis factor-α（TNF-α）in the observation group were significantly lower than those in the control group［（59.73±11.42）ng/L，（3.87±1.08）ng/L，（9.77±2.38）ng/L vs（65.71±12.13）ng/L，（5.27±1.20）ng/L，（11.21±2.61）ng/L］（P<0.05）. No serious adverse reactions occurred in both groups.

Danggui Dilong Guizhi Decoction combined with acupuncture has a significant effect on the treatment of cervical spondylosis pain and upper limb numbness，it can improve the symptoms of pain and upper limb numbness，enhance the cervical spine function，improve the muscle strength and reduce the inflammatory response，it is safe and worthy of application.