• Chenjing MA , Shifan HAN , Yiwen ZHAO , Junxiang CHENG , Xuan LING , Qia LIU , Xinyu LI , Jun ZHANG , Huan ZHANG
    Chinese Nursing Research. 2026, 40(18): 3153-3161.
    Objective

    To investigate the application effectiveness of a food therapy regimen based on the family nurses dietary therapy theory in overweight and obese infertile women.

    Methods

    A total of 70 overweight and obese infertile women were selected as study subjects from the reproductive medicine clinic of a tertiary grade A hospital and a resident community in Taiyuan city,Shanxi province from June to July 2025.Following randomization and allocation concealment principles,the infertile women were divided into an intervention group(35 cases) and a control group(35 cases).The control group received health education combined with conventional dietary care,while the intervention group received health education combined with the family nurse food therapy regimen.Anthropometric indicators,dietary behaviors,and nutrient intake of the infertile women were investigated.

    Results

    After 6 weeks of intervention,the pregnancy rate in the intervention group was higher than that in the control group.Body weight,body mass index(BMI),waist-to-hip ratio(WHR),visceral fat area(VFA),body fat mass(BFM),fasting blood glucose(GLU),fasting insulin(FINS),homeostatic model assessment for insulin resistance(HOMA-IR),total cholesterol(TC),triglycerides(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),C-reactive protein(CRP),high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6),tumor necrosis factor-alpha(TNF-α),superoxide dismutase(SOD),malondialdehyde(MDA),homocysteine(Hcy),alanine aminotransferase(ALT),aspartate aminotransferase(AST),serum urea(UREA),serum creatinine(CREA),and serum uric acid(UA) in the intervention group were superior to those before the intervention.The degree of change in body weight,BMI,VFA,BFM,FINS,HOMA-IR,LDL-C,TG,CRP,hs-CRP,IL-6,TNF-α,SOD,and Hcy were greater in the intervention group than in the control group.Body weight in the intervention group at 3 months after intervention was lower than that at 6 weeks after intervention.The degree of reduction was greater than that in the control group.Total dietary energy,protein,fat,carbohydrate,and dietary fiber intakes in the intervention group were superior than those before the intervention.All these differences were statistically significant(all P<0.05).

    Conclusions

    The family nurses dietary therapy regimen was beneficial for improving glycolipid metabolism disorders and pregnancy outcomes,alleviating chronic inflammatory responses,modulating the oxidative stress balance,and simultaneously optimizing liver and kidney function in overweight and obese infertile women,thereby establishing a favorable physiological foundation for conception.

  • Xiyan ZHANG , Yiwen ZHAO , Ruifang ZHU , Shifan HAN
    Chinese Nursing Research. 2026, 40(18): 3162-3167.
    Objective

    To construct a dietary intervention program for childhood bronchial asthma based on the family nurse dietary therapy theory,and to evaluate its application effects.

    Methods

    A total of 232 children with bronchial asthma admitted to the department of pediatrics of the First Hospital of Shanxi Medical University were selected as study subjects from March 2023 to March 2025.The children were divided into a control group and an observation group using a random number table method,116 cases each.The control group received family-centered home rehabilitation nursing,while the observation group received the dietary intervention program for childhood bronchial asthma based on the family nurse dietary therapy theory in addition to the interventions given to the control group.Biochemical indicators,growth and development indicators,pulmonary function indicators,quality of life,sleep quality,asthma attack frequency,and asthma control level were compared between the two groups.

    Results

    During the study period,4 cases dropped out from the control group and 2 cases dropped out from the observation group.Ultimately,112 children in the control group and 114 children in the observation group completed the full follow-up.After 12 months of intervention,the observation group showed higher levels of serum albumin,hemoglobin,serum iron,ferritin,25-hydroxyvitamin D,serum zinc,serum calcium,percentage of forced vital capacity to predicted value,percentage of forced expiratory volume in the first second to forced vital capacity percentage of forced expiratory volume in 1 second to forced vital capacity and quality of life scores compared with the control group.The height-for-age Z-score and weight-for-age Z-score in the observation group were significantly improved compared with those in the control group.The fractional exhaled nitric oxide level and sleep quality scores in the observation group were lower than those in the control group.The number of acute asthma attacks and the number of hospitalizations due to asthma in the observation group were fewer than those in the control group.The asthma control level in the observation group was better than that in the control group (all P<0.05).

    Conclusions

    The application of the dietary intervention program for childhood bronchial asthma based on the family nurse dietary therapy theory in children with asthma could effectively improve the nutritional status of the children,promoted their growth and development,optimized their pulmonary function,reduced the frequency of acute asthma attacks,and enhanced both disease control and quality of life and sleep.

  • Donghui DAI , Tianyan HU
    Chinese Nursing Research. 2026, 40(18): 3168-3175.
    Objective

    To analyze the latent transition status of gastrointestinal symptom clusters and their influencing factors in patients with primary gastric cancer before and after chemotherapy.

    Methods

    A total of 219 patients with primary gastric cancer who received postoperative chemotherapy at the department of traditional Chinese medicine of The First Affiliated Hospital of Soochow University were selected as study subjects by a convenience sampling method from January 2024 to June 2025.The severity of gastrointestinal symptoms was assessed using the Chinese version of the MD Anderson Symptom Inventory-Gastrointestinal Cancer Module at 1-3 days before chemotherapy and 5-7 days after chemotherapy.Latent transition analysis was performed to explore the transition probabilities of gastrointestinal symptom classes before and after chemotherapy.Multivariate Logistic regression analysis was used to identify the influencing factors of latent transition in gastrointestinal symptom clusters.

    Results

    Gastrointestinal symptoms before and after chemotherapy in gastric cancer patients were classified into two groups,namely mild symptom group and symptom distress group.From pre-chemotherapy to post-chemotherapy,the probabilities of remaining in the same group were 48.7% for the mild symptom group and 77.5% for the symptom distress group.The probability of transitioning from the mild symptom group to the symptom distress group was 51.3%,while the probability of transitioning from the symptom distress group to the mild symptom group was 22.5%.Age,education level,body mass index,and clinical stage were identified as influencing factors for the latent transition of gastrointestinal symptom clusters before and after chemotherapy in patients with primary gastric cancer(P<0.05).

    Conclusions

    There was group heterogeneity in gastrointestinal symptoms among patients with primary gastric cancer before and after chemotherapy.Healthcare providers should accurately identify the transition patterns of symptom clusters and their influencing factors,and implement precise symptom management strategies.

  • Ailin LI , Xiaomeng LU , Qingqiuyue ZHOU , Tianyuan LI , Nanping DUAN , Xinghan WU , Jianzhi LI
    Chinese Nursing Research. 2026, 40(18): 3176-3184.
    Objective

    To identify the latent classes of symptom distress in elderly patients with heart failure and to construct a risk prediction model using machine learning algorithms.

    Methods

    A convenience sampling method was used to select 460 elderly patients with heart failure who were hospitalized in the department of cardiology of a tertiary grade A hospital in Hengyang city from September 2023 to April 2024 as the study subjects.Latent class analysis was employed to explore the latent classes of symptom distress in these elderly patients with heart failure. Six risk prediction models of symptom distress in elderly patients with heart failure were constructed using machine learning algorithms.The optimal model was selected and subjected to interpretability analysis.

    Results

    Symptom distress in elderly heart failure patients was classified into three latent classes.The low-distress symptom-adaptation group accounted for 44.8%(206 cases).The moderate-distress psychological-dysregulation group accounted for 26.5%(122 cases).The high-distress heart-failure-predominant group accounted for 28.7%(132 cases).LASSO regression analysis showed that age,educational level,average monthly household income,multimorbidity,smoking,and perceived social support were significant influencing factors of symptom distress in elderly heart failure patients.Machine learning algorithms were used to construct six models,namely logistic regression,decision tree,random forest,K-nearest neighbors,extreme gradient boosting and support vector machine.The area under the receiver operating characteristic curve of extreme gradient boosting in the training set and test set was 0.909 and 0.828,respectively.Which was higher than that of the other models.The calibration curve showed that the predictions of extreme gradient boosting were in good agreement with the actual results.Within a certain threshold probability range,the decision curve of extreme gradient boosting demonstrated that the model possessed favorable clinical application performance.The learning curve showed no overfitting of the extreme gradient boosting.The interpretability analysis based on extreme gradient boosting revealed that perceived social support,multimorbidity,and age were of high importance.

    Conclusions

    Symptom distress in elderly patients with heart failure exhibits population heterogeneity.The extreme gradient boosting model demonstrates good performance in predicting the risk of symptom distress in elderly patients with heart failure.

  • Lijun GUAN , Yanxiu LIU , Fuying PENG
    Chinese Nursing Research. 2026, 40(18): 3185-3191.
    Objective

    To explore the potential categories of postoperative olfactory function recovery trajectories in patients with chronic rhinosinusitis with nasal polyps(CRSwNP) and to analyze the influencing factors of these categories.

    Methods

    A total of 300 CRSwNP patients who underwent endoscopic sinus surgery at Ganzhou Hospital of Nanfang Hospital, Southern Medical University were selected as the study subjects from January 2023 to April 2025.Olfactory function was assessed using the T&T standard olfactory test method preoperatively and at 1,3, and 6 months postoperatively.Latent variable mixed growth modeling was employed to identify the potential trajectory categories of olfactory recovery in CRSwNP patients.The univariate and multivariate analyses were conducted to explore the influencing factors of the latent categories.

    Results

    The postoperative olfactory recovery trajectories in CRSwNP patients were classified into three categories,namely rapid recovery type (154 cases,51.3%),slow recovery type (92 cases,30.7%),and poor recovery type(54 cases,18.0%).Multivariate analysis revealed that comorbid allergic rhinitis,history of endoscopic sinus surgery,olfactory cleft polyps,postoperative complications,Lund-Mackay score,serum total IgE level,and blood eosinophil percentage were influencing factors for the trajectory categories of postoperative olfactory recovery in CRSwNP patients(all P<0.05).

    Conclusions

    Group heterogeneity existed in the postoperative olfactory recovery trajectories among CRSwNP patients.Comorbid allergic rhinitis,history of endoscopic sinus surgery,and olfactory cleft polyps and so on are key factors affecting the recovery trajectory categories.Early identification of high-risk populations based on these influencing factors and the development of targeted intervention strategies could improve olfactory outcomes of patients.

  • Yunlong YU , Suile ZHANG , Lei CHEN , Yao LUO , Shuang LI , Yueming PENG
    Chinese Nursing Research. 2026, 40(18): 3192-3198.
    Objective

    To identify the latent profiles of professional socialization in nursing interns, and to reveal their heterogeneous characteristics and the influencing factors.

    Methods

    A convenience sampling method was adopted,a total of 386 nursing interns from five tertiary hospitals in China were selected as research subjects from August to October 2025.Data were collected using a general information questionnaire,the Perceived Academic Support Scale for Nursing Interns,the Career Adapt-Abilities Scale,and the Professional Socialization Scale for Nursing Students.A latent profile model was constructed using Mplus 8.3 software.

    Results

    Group heterogeneity was observed in the level of professional socialization in nursing interns,and three latent profiles were identified,namely role-drifting type,identity-constructing type,and belonging-integrating type.Age,satisfaction with the nursing major,perceived academic support,and career adaptability were significant influencing factors of the latent profiles(all P<0.05).

    Conclusions

    Nursing educators should pay attention to the group heterogeneity of professional socialization in nursing interns.They should also identify and focus on those in the role-drifting type,and implement differentiated interventions to guide them toward the identity-constructing type,ultimately facilitating a deeper transformation toward the belonging-integrating type and achieving full role internalization.

  • Cailian WANG , Shoulin ZHU , Lejiao HUANG , Hanyue ZENG , Yinsen PENG , Yun LI , Shifang MAO
    Chinese Nursing Research. 2026, 40(18): 3199-3205.
    Objective

    To construct symptom networks in patients with end⁃stage kidney disease before and after dialysis and to explore the dynamic interactions among different symptoms over time.

    Methods

    A total of 299 patients undergoing initial hemodialysis treatment at a tertiary grade A hospital in Sichuan province were selected as the study subjects from November 2024 to September 2025.Patients were surveyed using a self⁃designed general demographic questionnaire and an adapted version of the Dialysis Symptom Assessment Scale.A cross⁃lagged network model was employed to identify dynamic interactions among 18 symptoms over time.

    Results

    The forward time⁃lagged correlation was sleep difficulty→itching(β=0.33).The backward time⁃lagged correlation was fatigue or lack of energy→sleep difficulty(β=-0.22).Sleep difficulty reported the greatest out⁃predictability(0.265),in⁃predictability(0.233),out⁃strength(1.498),and in⁃strength(1.591).

    Conclusions

    Sleep difficulty was identified as the core symptom of the dynamic network model of symptom before and after dialysis in patients with end⁃stage renal disease.Strategies to alleviate sleep difficulty should be incorporated into multimodal interventions for end⁃stage kidney disease.

  • Xiaohong MENG , Zhaojie CHANG , Jing LI , Meixia REN , Yuan ZHAO , Jiaqi LI , Yuling LI
    Chinese Nursing Research. 2026, 40(18): 3206-3212.
    Objective

    To investigate the clinical evidence-based nursing practice competence among master of nursing specialist students and analyze its influencing factors.

    Methods

    A mixed-methods study with an explanatory sequential design was adopted.For the quantitative phase,convenience sampling was used to select 130 master of nursing specialist students from four tertiary grade A hospitals in Shanxi province from March to May 2023.The participants were surveyed using a general information questionnaire and the Chinese version of the Evidence-Based Practice Questionnaire.For the qualitative phase,a total of 19 master of nursing specialist students were selected to participate in semi-structured interviews from the quantitative study sample.

    Results

    The total score on the Chinese version of the Evidence-based Practice Questionnaire among the 130 master of nursing specialist students was 115.95±21.04,with an average item score of 4.64±0.84.Regression analysis showed that research experience(participating in academic conferences and research projects and so on),awareness of the importance of clinical evidence-based nursing practice,and knowledge of clinical evidence-based nursing practice were influencing factors for the score on the Chinese version of the Evidence-Based Practice Questionnaire(all P<0.05).The qualitative analysis extracted four themes,namely high recognition and internalization of values,identifying clinical evidence-based nursing practice as a professional development direction;weak practical competence and lack of systematic support,leading to a knowing-doing gap;multidimensional facilitating factors stimulating the implementation of clinical evidence-based nursing practice;and multiple barriers constraining the clinical application of evidence-based nursing practice.

    Conclusions

    The clinical evidence-based nursing practice competence among master of nursing specialist students was at a moderate level.Hospitals and schools should improve teaching methods based on students' learning needs and experiences, provide more support,and enhance their clinical evidence-based nursing practice competence.

  • Mei WANG , Xiao YUE , Huifen LING , Jiaqi XU , Rong ZHOU , Wanling LI
    Chinese Nursing Research. 2026, 40(18): 3213-3219.
    Objective

    To explore the level of intrinsic capacity in hospitalized elderly patients and its impact on their quality of life.

    Methods

    A total of 602 hospitalized elderly patients from Hubei,Henan,and Hunan provinces were selected as study subjects by a convenience sampling method from January to June 2024.Surveys were conducted using a general information questionnaire,the Intrinsic Capacity Screening Tool,and 36-item Short Form Health Survey.Univariate analysis,Spearman correlation analysis,and stepwise linear regression analysis were used to explore the influencing factors of quality of life in hospitalized elderly patients.

    Results

    The total intrinsic capacity score of hospitalized elderly patients was 3(2,4).The total quality of life score was 66.37±5.34.Regression analysis showed that the total intrinsic capacity score and its dimension scores,along with age,sex,living situation,medical expense payment method,per-capita household disposable income,pain,sleep problems,polypharmacy,and mode of admission,were all influencing factors on the quality of life in hospitalized elderly patients(all P<0.05).Among these,the dimensions of locomotion,psychological status,and vitality had more significant effects on quality of life.

    Conclusions

    The level of intrinsic capacity in hospitalized elderly patients affects their quality of life,with locomotion,psychological status,and vitality being the most significant dimensions.Medical staff may consider incorporating intrinsic capacity assessments into the early management of hospitalized patients.They could implement comprehensive interventions targeting key functional dimensions and modifiable factors so as to promote functional maintenance and to improve quality of life in hospitalized elderly patients.

  • Tao HU , Bo XU , Zhijun CHEN , Yu SU , Huan XU , Ling YI
    Chinese Nursing Research. 2026, 40(18): 3220-3225.
    Objective

    To analyze the smart health care service demands of postoperative thyroid cancer patients based on the Kano model.

    Methods

    A convenience sampling method was adopted.A total of 280 postoperative thyroid cancer patients in our hospital were selected as study subjects from May 2022 to June 2025.The patients were surveyed using a self-designed Kano model demand attribute questionnaire for postoperative thyroid cancer patients.Kano model demand attribute classification, better coefficient-worse coefficient analysis,two-dimensional matrix analysis,and sensitivity analysis were performed.

    Results

    A total of 15 demands fell into the priority improvement area,including 4 must-be attributes(26.67%),5 attractive attributes(33.33%),and 6 one-dimensional attributes(40.00%).Sensitivity analysis of the demands was conducted.The highest sensitivity value was 0.327,and the lowest was 0.062.The items "remote alert for hypocalcemia","reminder push for follow-up visits",and "swallowing function rehabilitation guidance" showed relatively high sensitivity.

    Conclusions

    Based on the analysis results of smart health care service demands of postoperative thyroid cancer patients,nursing workers could focus on remote alert for hypocalcemia,reminder push for follow-up visits,and swallowing function rehabilitation guidance and so on to develop higher-quality nursing plans.

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