To assess the impact of environmental factors on the chronic respiratory disease (CRD) burden among the Chinese population during 1990—2021, providing scientific evidence for formulating targeted prevention strategies and clinical interventions.

Based on the data of the Global Burden of Disease Study 2021 (GBD 2021), this study adopted descriptive epidemiological methods to analyze the disease burden indicators of chronic respiratory diseases (CRD). Further, the Joinpoint regression model was used to analyze the temporal trend changes of disease burden, and the Age-Period-Cohort (APC) model was constructed to systematically evaluate the impact of environmental risk factors on the disease burden of CRD.

Both the CRD-standardised mortality rate and the standardised DALY rate showed a decreasing trend over the period (P<0.05). As of 2021, outdoor particulate matter has become the primary contributor to the burden of chronic respiratory disease in China. The impact of environmental factors on the disease burden of CRD in China increased with age, with those aged 80 years or older being the most severely affected. Cohort analyses showed that people born in 1912—1951 were more affected by environmental factors, especially indoor air pollution and ambient particulate matter.

The long-term impact of environmental factors on the disease burden of CRD among Chinese residents still cannot be ignored. It is necessary to further strengthen environmental monitoring, formulate and implement stricter environmental standards, especially in controlling outdoor air pollution.

To investigate the association between Tsampa consumption and biological age acceleration.

Utilizing baseline data from the China Multi-Ethnic Cohort study (CMEC), a composite biomarker-based biological age was constructed using the Klemera-Doubal Method (Biological age based on Klemera and Doubal’s method, KDM-BA). Biological aging was quantified as the difference between KDM-BA and chronological age. Tsampa consumption information was obtained via a Food Frequency Questionnaire (FFQ). Weekly intake was calculated based on consumption frequency and gram weight, and participants were categorized into four groups: non-consumption, low, moderate, and high, based on the 25th and 75th percentiles. Multiple linear regression was employed to analyze the association between Tsampa consumption and biological age acceleration. Stratified analyses were conducted using sex, age, smoking, alcohol consumption, and BMI as stratification factors.

A total of 4 335 participants were included. Compared to non-consumption, Tsampa consumption showed a negative association with biological age acceleration(β=-0.66,95% CI:-0.99- -0.327). A statistically significant association was found for moderate Tsampa consumption (700-1 400 grams)(β=-1.24,95% CI: -2.04- -0.44). Associations for low and high consumption levels were not statistically significant [Low:(β=0.11, 95% CI:-0.67-0.88); High:(β=-0.39,95% CI:-1.37-0.60)]. The protective effect of Tsampa consumption against biological age acceleration was stronger in males than in females [Males: (β=-0.83, 95% CI: -1.24- -0.43); Females:(β=-0.61,95% CI:-1.08- -0.13)].

Tsampa consumption is negatively associated with biological age acceleration, suggesting its potential beneficial role in promoting healthy aging in the Tibetan region.

To assess the exposure levels and potential health risks of benzoic acid, sorbic acid, saccharin sodium, and cyclamate in sweet and sour pickled vegetables for sale in Wuhan.

Utilizing the monitoring data of benzoic acid, sorbic acid, saccharin sodium, and cyclamate in sweet and sour pickled vegetables from the Wuhan Food Safety Risk Surveillance Program from 2021 to 2024, the point assessment method and the safety limit method were used to evaluatethe exposure risks of these additives.

The detection rates of benzoic acid, sorbic acid, saccharin sodium, and cyclamate in sweet and sour pickled vegetables (n=790)were 83.0%, 45.2%, 49.6%, and 77.5%, respectively. The over-standard rates of benzoic acid, saccharin sodium, and cyclamate were 3.4%, 4.2%, and 2.8%, respectively. The maximum concentrations of benzoic acid, sorbic acid, saccharin sodium, and cyclamate were 2.21 g/kg, 0.837 0 g/kg, 0.963 0 g/kg, and 3.13 g/kg, respectively. The average daily exposure to benzoic acid, sorbic acid, saccharin sodium, and cyclamate was well below their respective ADI values. Cumulative risk assessment showed that the Hazard Index (HI) of the four additives combined was less than 1.

The exposure risk from sweet and sour pickled vegetables in this study was within an acceptable rang.

To understand the main dietary heavy metal pollution situation of Huanggang residents, and to analyze the sources of pollution, and evaluate the health risks of heavy metal intake through dietary pathways.

From 2019 to 2023, a total of 1 402 samples from 11 major categories and 30 subcategories were collected and detected in ten counties and districts of Huanggang City. The Nemerow contamination index method, Spearman rank correlation test, cluster analysis, and principal component analysis were usedto comprehensively evaluate the food contamination situation and possible sources. Evaluate the non carcinogenic and carcinogenic health risks of the population using the total target hazard quotient (TTHQ) and total target carcinogenic risk (TTCR).

The average content of heavy metals(Pb、Cd、Hg、As、Cr) in food was 0.007-0.217 mg/kg, 0.001-0.632 mg/kg, 0.001-0.012 mg/kg, 0.003-0.103 mg/kg, and 0.005-0.376 mg/kg, respectively. The detection rate of heavy metals was 0.0%-100.0%, and the exceedance rate was 0.0%-31.7%. Except for Hg, there were statistically significant differences in the content, detection rate, and exceedance rate of heavy metals in different types of food (P<0.001). The detection rate and exceedance rate of heavy metals in edible fungi were relatively high. Region, season, stage, processing level, moisture content, and packaging level were all influencing factors of heavy metal content in food. The two possible sources of heavy metals in edible fungi were industrial emissions and traffic exhaust. Except for bamboo fungus and shiitake mushrooms, which were heavily and mildly contaminated respectively, all other foods were safe. The TTHQ of different populations was between 1 and 10, and the TTCR was greater than 1×10^-4. Children had higher TTHQ than adults, and females had higher TTCR than males. The main sources of heavy metals for TTHQ and TTCR in the population were total As and Cd.

The overall degree of heavy metal pollution in the main diets of Huanggang City is still within a controllable range. There may be certain cumulative health risks of heavy metals for residents through dietary intake, and special attention should be paid to the health risks of children.

To investigate the dose–response relationship between different levels of physical activity and sedentary time and mental health among primary and secondary school students, thereby providing a robust scientific basis for the effective prevention of mental health problems in children and adolescents.

A health survey was conducted among 3 982 students selected by convenience sampling from eight primary and secondary schools in Haizhu District, Guangzhou. Mental health status was compared between students with and without regular physical activity habits. Zero-inflated negative binomial (ZINB) models and generalized additive models (GAMs) were subsequently employed to analyze the dose–response relationship between physical activity, sedentary behavior, and mental health outcomes.

Among the 3 982 participants, only 5.73% met the World Health Organization’s recommended levels of physical activity. Sedentary time was generally excessive, with only 25.24% of students reporting sedentary time of 3 hours or less per day. After stratified propensity score matching, significant differences in the number of days feeling unhappy were observed across all six matched groups between students with and without regular physical activity habits. Compared with ≤10 minutes of daily moderate-to-vigorous physical activity (MVPA), longer durations of MVPA and outdoor activity were associated with improved mental health outcomes, with greater benefits observed as activity duration increased (MVPA: 11–29 minutes: +21.55%, 30–59 minutes: +24.19%, ≥60 minutes: +25.86%; outdoor activity: 11–30 minutes: +23.81%, 31–44 minutes: +19.19%, 45–60 minutes: +25.42%, ≥60 minutes: +28.28%). In contrast, compared with ≤3 hours of sedentary time, longer durations of sedentary behavior were associated with poorer mental health (3–4 hours: -9.40%, 4–5 hours: -15.43%, >5 hours: -44.27%). The GAM analysis further confirmed the findings of the ZINB modeL.

A dose–response relationship exists between physical activity, sedentary behavior, and mental health among primary and secondary school students. Longer durations of physical activity are associated with greater mental health benefits, while prolonged sedentary time is linked to poorer mental health outcomes. These findings provide empirical support for optimizing youth-targeted physical activity interventions and mental health promotion policies.

To explore the status quo of disease perception stress of primary infertility patients in childbearing age, and analyze the relationship between it and couples’ support and coping.

A total of 798 primary infertility patients of childbearing age admitted to the hospital from January 2023 to January 2025 were selected for the study. The General information Questionnaire, the Simplified version of the Disease Perception Questionnaire (BIPQ) scale, the Marital Support Coping (DCI) Scale, and the Stigma Scale for Female Infertility Patients (ISS) were used for the investigation.

The BIPQ score of primary infertility in childbearing age was (55.67±6.43), and the pressure of disease perception was high. Pearson correlation analysis showed that BIPQ score was negatively correlated with DCI score (r=-0.243) and positively correlated with ISS score (r=0.309) (P<0.05). The results of multiple linear regression analysis showed that the higher the age, the higher the stress of patients (B=2.996, 95% CI: 2.349-3.642), the higher the educational level, the lower the pressure (B=-2.149,95% CI: -2.831--1.468), the higher the pressure of patients who think that childbirth is the most important thing in life (B=4.969, 95% CI:4.277-5.661), and the worse the relationship between husband and wife, the higher the pressure (B=2.396, 95% CI: 1.692-3.100), the higher the DCI score, the lower the stress (B=-0.044, 95% CI:-0.065--0.022), and the higher the ISS score, the higher the stress(B=0.077, 95% CI:0.055-0.099) (P<0.05).

The primary infertility patients in childbearing age have a high level of disease perception pressure, so we should focus on those who are older, have low educational level, have a traditional concept of fertility, have poor relationship between husband and wife and have a high sense of shame, and formulate corresponding intervention strategies to improve the mental health level of patients.

To assess the current utilization of health services and the influencing factors among women of childbearing age in rural and pastoral areas of Xizang, and to provide evidence-based recommendations for improving healthcare accessibility in Xizang.

Using data from the Seventh National Health Service Survey in Xizang and guided by the Andersen’s Health Service Utilization Behavior Model, we analyzed factors influencing healthcare utilization among 2 025 women aged 15-49 in rural and pastoral areas. In addition, focus group interviews were conducted to complement the quantitative findings.

The two-week outpatient visit rate among women of childbearing age was 5.93%, and the inpatient admission rate within the past year was 8.99%. Binary logistic regression analysis revealed that women with urban-rural medical insurance (OR=0.142, 95% CI: 0.035-0.571) and those with a self-rated health score ≥80 (OR=0.315, 95% CI: 0.179-0.554) were less likely to use outpatient services. In contrast, women who had signed up for family doctor services (OR=2.310, 95% CI: 1.036-5.152), were unaware of such services (OR=2.818, 95% CI: 1.125-7.056), or had chronic conditions (OR=3.081, 95% CI: 2.043-4.646) showed significantly higher outpatient utilization. In terms of inpatient services, lower utilization was observed among women aged 25-34 (OR=0.473, 95% CI: 0.277-0.809), 35-44 (OR=0.228, 95% CI: 0.127-0.407), and 45-49 (OR=0.191, 95% CI: 0.096-0.379), as well as those with a history of alcohol consumption (OR=0.366, 95% CI: 0.225-0.595). Conversely, higher inpatient utilization was associated with having a primary school education (OR=1.652, 95% CI: 1.128-2.421), being married (OR=2.925, 95% CI: 1.648-5.192), being employed (OR=2.587, 95% CI: 1.388-4.821), and having chronic illnesses (OR=2.351, 95% CI: 1.667-3.317). Qualitative analysis indicated that poor transportation, limited health awareness, financial constraints, and dissatisfaction with medical services were the primary barriers to healthcare utilization.

The utilization of health services among women of childbearing age in surveyed areas of Xizang remains suboptimal. Efforts to enhance service utilization should focus on strengthening health education, expanding healthcare infrastructure, and improving service quality in rural and pastoral regions.

To explore the impact of social support on sleep quality among elderly people, and investigate the mediating role of anxiety symptoms between social support and sleep quality. The goal is to provide scientific evidence for improving sleep quality in this population.

Social Support scale, Generalized Anxiety Disorder 7-item (GAD-7), and Pittsburgh Sleep Quality Index (PSQI) were used to evaluate social support, anxiety symptoms and sleep quality of older adults. After excluding outliers and missing values, Pearson correlation analysis and multiple linear regression models were employed to examine the relationships among social support, anxiety symptoms, and sleep quality in older adults. The Bootstrap method was applied to test the mediating effect of anxiety symptoms.

A total of 1 194 participants were included, including 717 females (60.1%). Social support was negatively correlated with anxiety symptoms and sleep quality index (r= -0.180, P<0.001; r= -0.148, P<0.001), while anxiety symptoms were positively correlated with sleep quality index (r= 0.349, P<0.001). Mediation analysis revealed that anxiety partially mediated the relationship between social support and sleep quality, accounting for 37.5% of the total effect. Among men, anxiety symptoms accounted for 21.4% of the mediating effect, while among women, they accounted for 46.2%.

Better social support is associated with lower anxiety levels and improved sleep quality. Providing adequate social support for community-dwelling older adults is crucial for enhancing their sleep quality, physical health, and mental well-being.

To understand the demand for and preferences of mental health services among residents in Shanghai communities, providing a basis for service design and policy-making.

Using discrete choice experiments, we surveyed 647 permanent residents aged 16 and above in Shanghai regarding their preferences for seven attributes of mental health services under varying degrees of psychological distress: distance from the service provider to home, type of service provider, composition of service providers, service medium, service content, service stability, and the cost per service.

The cost of service (mild psychological distress β=0.398, severe psychological distress β=0.320), type of service provider (mild β=0.224, severe β=0.210), service stability (mild β=0.112, severe β=0.132), composition of service providers (mild β=0.101, severe β=0.120), and distance to the service provider (mild β=0.109, severe β=0.124) were identified as key attributes influencing residents’ choices of mental health services. Willingness-to-pay analysis showed that residents were more willing to pay for services within 15 km (mild WTP=328.837, severe WTP=464.453), services provided by public mental health institutions (mild WTP=676.65, severe WTP=788.226), services delivered by psychotherapists (mild WTP=303.584, severe WTP=449.14), face-to-face plus online services, basic supportive services (mild WTP=31.056, severe WTP=86.389), and stable services (mild WTP=339.593, severe WTP=494.968).

Accessibility and stability of services are key attributes influencing service choice. The selection of service providers is characterized by a preference for public institutions as the mainstay, supplemented by non-profit organizations. Residents have a higher willingness to pay for supportive “psychotherapy” compared to medical intervention and rehabilitation services. It is recommended to strengthen the construction of grassroots service networks, enhance accessibility and stability, optimize processes, and establish coordinated mechanisms to improve satisfaction and utilization of mental health services.

To investigate the impact of community-based elderly care service utilization on mental health outcomes and its underlying pathways among older adults with chronic diseases, providing evidence for targeted interventions in this population.

A descriptive statistical and correlation analysis was conducted on the use of community-based elderly care services, mental health, and social adaptability among 280 elderly individuals aged 60 and above with chronic diseases. The mediating effect of social adaptability was tested using the Bootstrap method.

The service utilization rate reached 60% among participants, with a mean GHQ-12 score of 18.41±4.75. Significant positive correlations emerged between service utilization and social adaptation(r=0.288, P<0.001). Both service utilization and social adaptation demonstrated negative associations with psychological distress (r=-0.365,P<0.001;r=-0.464,P<0.001). The utilization of community-based elderly care services by older adults with chronic diseases negatively influences GHQ-12 scores by enhancing their social adaptability, with the mediating effect of social adaptability accounting for 30.81% of the total effect.

Community-based elderly care services exert beneficial effects on mental health in older adults with chronic diseases, partially mediated through enhanced social adaptability.