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To investigate the impact of air pollution on blood pressure control in hypertensive patients.
Data from the China Health and Nutrition Survey collected between 2011 and 2015 were analyzed, including 2 860 participants from Shanghai, of which 831 were hypertensive patients. Air pollution monitoring data for Shanghai during the same period were obtained from the National Urban Air Quality Release Platform. Demographic information, daily habits, health status, and hypertension-related data were collected via questionnaires. Logistic regression was employed to analyze the effect of air pollutants on achieving blood pressure targets, and a mixed-effects model was used to study interactions among air pollutants and their interactions with antihypertensive medications.
A total of 831 adult hypertensive patients were included, with a blood pressure control rate of 35.14%. The odds ratios (OR) and 95% confidence intervals (CI) for O3 exposure on day 0, the previous 7 days, and the previous 60 days were 1.012 (1.005-1.020), 1.009 (1.002-1.016), and 1.013 (1.003-1.022), respectively. For CO during the same periods, the OR and 95%CI were 1.084 (1.030-1.140), 1.064 (1.030-1.100), and 1.126 (1.050-1.208), respectively. The OR and 95%CI for SO2 on day 0 and the previous 7 days were 1.056 (1.004-1.110) and 1.024 (1.003-1.046), respectively. SO2 exposure on day 0 and the previous 7 days (P=0.008; P=0.043) and CO exposure in the previous 60 days (P<0.001) may influence the effectiveness of antihypertensive medications; CO on day 0 and SO2 on the same day may interact regarding blood pressure control rates (P=0.045); O3 exposure in the previous 7 days, SO2 on the same day, and CO on the same day may also interact concerning blood pressure control rates (P=0.004; P<0.001).
O3, SO2, and CO are associated with blood pressure control rates. Recent and long-term exposure to O3 and CO may affect blood pressure control, while recent exposure to SO2 may influence the efficacy of antihypertensive medications. It is recommended to enhance air pollution monitoring and management, providing guidance for hypertensive patients to improve blood pressure control outcomes.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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