To explore the clinical efficacy of Jianpi Lishi Jiedu Decoction（健脾利湿解毒汤）combined with pidotimod in the treatment of low-grade squamous intraepithelial lesions（LSIL）of the cervix combined with high-risk human papillomavirus（HPV）infection.

A totalof130 cases of LSIL complicated with high-risk HPV infection admitted to the hospital from January 2022 to September 2023 were included and divided into two groups using the computer random number table method，with 65 cases in each group.The control group was treated with pidotimod，while the observation group was treated with Jianpi Lishi Jiedu Decoction on the basis of the control group.The treatment lasted for 3 months.The clinical efficacy of two groups，the traditional Chinese medicine syndrome score and serum inflammatory factor levels［high-sensitivity C-reactive protein（hs-CRP），interleukin-12（IL-12）and tumor necrosis factorα（TNF）-α）］and changes in viral load were compared.

①The total effective rate of the observation group was 93.85%，which was higher than that（81.54%）of the control group（χ²＝4.561，P＝0.033）.②The difference in traditional Chinese medicine syndrome scores for vaginal discharge，itching，fatigue，edema and loose stools in the observation group was lower than that in the control group［（1.13±0.13）points vs.（2.05±0.16）points，（1.09±0.11）points vs.（1.65±0.15）points，（1.01±0.19）points vs.（1.66±0.22）points，（0.68±0.17）points vs.（1.13±0.19）points，（0.89±0.18）points vs.（1.38±0.14）points］（t＝35.979～17.324，all P<0.01）.③The serum levels of TNF-α and hs-CRP of the observation group were all lower than those of the control group［（1.13±0.36）pg/mL vs.（1.72±0.41）pg/mL，（2.19±0.45）mg/L vs.（4.24±0.87）mg/L］（t＝8.718-16.874，all P<0.01），and the serum IL-12 levels were higher than the control group［（16.52±5.03）pg/mL vs.（14.25±5.16）pg/mL］（t＝-2.540，P＝0.006）.④The recurrence rate［4.61%（3/65）］in the observation group was significantly lower than that［16.92%（11/65）］in the control group（χ²＝5.123，P＝0.024）.The HPV viral load in the observation group was lower than that in the control group［（1.85±0.59）Igcopies/mL vs.（2.73±0.65）Igcopies/mL］（t＝-8.082，P<0.01），and the seroconversion rate was higher than that in the control group（69.23% vs.43.08%）（χ² ＝9.029，P＝0.003）.

The combination of Jianpi Lishi Jiedu Decoction and pidotimod in the treatment of LSIL complicated with high-risk HPV infection has a definite therapeutic effect.It can restore the patient's immune inflammatory balance and reduce the HPV viral load.

This study aims to explore the potential categories of five pattern personalities and analyze the differences of each category on the Big Five Personality.

A total of 963 volunteers were recruited to participate in the study.The survey was conducted using the Five Pattern Personalities Inventory and Big Five Personality Inventory.The latent categories of five pattern personalities were analyzed using latent profile analysis.

1）It was found that there were five latent categories of five pattern personalities：“low Yang-low Shaoyin-high Taiyin group”（12.56%），“low Yang-high Yin group”（27.73%），“high Yang-high Shaoyin low Taiyin group”（37.49%），“high Yang-high Yin group”（5.93%），“high Yanglow Yin group”（16.34%）.2）The five latent categories of five pattern personality exhibited significant differences in each dimension of the Big Five Personality（P<0.001）.The“low Yang group”（categories 1 and 2）demonstrated significantly lower levels of openness，extroversion and agreeableness compared to the“high Yang group”（categories 3 and 5）（P<0.001），while scoring higher on neuroticism than the“high Yang group”.Additionally，the rigor score for the“high Yang-high Shaoyin low Taiyin group”was significantly higher than other groups，whereas it was lower for the“low Yang-low Shaoyin high Taiyin group”.Furthermore，extraversion and agreeableness scores were lower for“high Yang-high Yin group”compared to“high Yang group”but higher than those for“low Yang group”；neuroticism scores were lower than those for“low Yang group”but higher than those for“high Yang group”as well.

There are five potentially categories of five pattern personalities.These different latent categories were significantly different on the Big Five Personality.

To explore the clinical effect of ultrasound-guided needle knife dissection combined with lumbar inclined plate method in the treatment of gluteal epithelial nerve compression syndrome based on the theory of“bone alignment and tendon flexibility”.

Sixty patients with gluteal epithelial nerve compression syndrome who received treatment in the Orthopedic Department of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from January 2023 to January 2024 were selected as the study subjects.Using the random number allocation method，the patients were randomly divided into a control group（30 cases）and an experimental group（30 cases）.The control group was treated with ultrasound-guided needle knife dissection，while the experimental group was treated with a combination of ultrasound-guided needle knife dissection and lumbar inclined plate dissection under the guidance of the“bone alignment and tendon flexibility”theory.The treatment period for both groupswas 4 weeks.After treatment，the clinical efficacy，Visual Analog Scale（VAS）score，Oswestry Disability Index（ODI）score，shear wave Young'smodulus values of the lumbar multifidus and psoasmajor muscles，and the changes in surface electromyography were compared between the two groups.

Compared with the control group，the experimental group had a higher clinical total effective rate after 4 weeks of treatment，but there was no statistically significant difference in the total effective rate between the two groups（P>0.05）.Compared with those before treatment，VAS scores and ODI scores in both groups showed a decreasing trend after treatment and 4 weeks follow-up（P<0.05）.Compared with those of the control group，the VAS score and ODIscore of the experimental group were lower after treatment and 4 weeks follow-up（P<0.05）.Compared with those before treatment，the shearwave Young'smodulus values of the bilateral multifidus and lumbar muscles in the experimental group showed a decreasing trend after treatment and 4 weeks follow-up（P<0.05）.Compared with those before treatment，there was no statistically significant difference in the shearwave Young'smodulus values of the bilateral multifidus and lumbar muscles in the control group after treatment and 4 weeks follow-up（P>0.05）.Compared with the control group，the shearwave Young'smodulus values of the bilateral multifidus and lumbar muscles in the experimental group were lower after treatment and 4 weeks follow-up（P<0.05）.Compared with those before treatment，the average amplitude of electromyography on both sides of the multifidus and lumbar muscles in the experimental group showed an increasing trend after treatmentand 4 weeks follow-up（P<0.05）.Compared with those before treatment，there was no statistically significant difference in the average amplitude of surface electromyography of the multifidus and psoasmajormuscles in the control group after treatmentand 4 weeks follow-up（P>0.05）.Compared with those in the control group，the average amplitude of surface electromyography of the multifidus and psoasmajor muscles in the experimental group was higher after treatment and 4 weeks follow-up（P<0.05）.

The combination of ultrasound-guided needle knife dissection method and lumbar inclined plate method based on the concept of“bone alignment and tendon flexibility”can significantly improve the short-term and long-term clinical effects of treating gluteal epithelial nerve compression syndrome，with advantages such as high safety，minimal trauma and rapid recovery.

To analyze the clinical effect of Shenqi Fuzheng Kang’ai Decoction（参芪扶正抗癌汤）combined with bevacizumab in the treatment of advanced colorectal cancer with Qiand blood deficiency syndrome.

The clinical data of 98 patients with advanced colorectal cancer who were admitted to the Affiliated Hospital of Nantong University from January 2022 to January 2024 was retrospectively analyzed.According to the treatment methods，they were divided into the conventional group（48 cases）and the combined group（50 cases）.Both groups were treated with XELOX chemotherapy.The conventional group was treated with bevacizumab，and the combined group was treated with Shenqi Fuzheng Kang’ai Decoction on this basis.The TCM syndrome score，tumor markers，T lymphocyte subsets，chemotherapy tolerance and quality of life score，clinical efficacy，adverse reactions and survival analysis of the two groups were observed.

After treatment，the TCM syndrome score and the levels of carcinoembryonic antigen（CEA），carbohydrate antigen 125（CA125），alpha-fetoprotein（AFP）and cytokeratin 19 fragment antigen 21-1（CYFRA21-1）in the combined group were lower than those in the conventional group（P<0.05）.The levels of CD3⁺and CD4⁺，the ratio of CD4⁺/CD8⁺，the scores of Karnofsky performance scale（KPS）and World Health Organization Quality of Life-BREF（WHOQOL-BREF）and the total effective rate in the combined group were higher than those in the conventional group（P<0.05）.There was no significant difference in the total incidence of adverse reactions between the two groups（P>0.05）.The progression-free survival（PFS）of the combined group was longer than that of the conventional group（P<0.05）.

Shenqi Fuzheng Kang’ai Decoction combined with bevacizumab in the treatment of advanced colorectal cancer with Qi and blood deficiency syndrome can effectively relieve the clinical symptoms of patients，improve the immunity，reduce the levels of tumormarkers，improve the clinical efficacy and quality of life，prolong the survival of patients，and has high safety.

To establish the infrared fingerprint spectra of standard decoctions of Xiangfu（Cyperi Rhizoma）and its processed products，and quickly identify the standard decoctions of Xiangfu（Cyperi Rhizoma）and its processed products.

Infrared fingerprint spectra were established for the decoctions of Xiangfu（Cyperi Rhizoma），wine-processed Xiangfu（Cyperi Rhizoma），vinegar-processed Xiangfu（Cyperi Rhizoma）and four-processed Xiangfu（Cyperi Rhizoma）.The differences among the average infrared spectra of the decoctions of Xiangfu（Cyperi Rhizoma），wine-processed Xiangfu（Cyperi Rhizoma），vinegar-processed Xiangfu（Cyperi Rhizoma）and four-processed Xiangfu（Cyperi Rhizoma）were analyzed using OMNIC 9.2 software.The common peaks of Xiangfu（Cyperi Rhizoma）and its processed product decoctions were identified using Spectrum forWindow 3.02 software and the relative peak heights were calculated.The differences among the processed Xiangfu（Cyperi Rhizoma）decoctions were compared using principal component analysis，orthogonal partial least squares-discriminant analysis and clustering analysis.

A total of 12 common peaks were identified and standardized for the decoctions of Xiangfu（Cyperi Rhizoma），vinegar-processed Xiangfu（Cyperi Rhizoma），wine-processed Xiangfu（Cyperi Rhizoma）and four-processed Xiangfu（Cyperi Rhizoma）using baseline correction and normalization.The differences were obvious in the 1700-1000 cm^-1 waveband，and fourmain contribution wavebands were selected，including2929 cm^-1，1053 cm^-1，997 cm^-1 and 1639 cm^-1.The processed Xiangfu（Cyperi Rhizoma）decoctionswere all clustered into four categories through analysis.

There are obvious differences among the decoctions of Xiangfu（Cyperi Rhizoma），vinegar-processed Xiangfu（Cyperi Rhizoma），wine-processed Xiangfu（Cyperi Rhizoma）and four-processed Xiangfu（Cyperi Rhizoma），and they can be quickly identified using infrared spectroscopy.The method is fast，effective and accurate.