Latest ArticlesTo analyze the study of the utility of five-element identification acupuncture in traditional Chinese medicine combined with ABA training in the treatment of children with autism.
Ninety cases of autistic children admitted to the Department of Pediatrics of Nanyang First People's Hospital Affiliated to Henan University from March 2022 to March 2024 were selected for the study.Forty-five cases of the control group were treated with ABA training,and the other 45 cases of the observation group were treated with traditional Chinese medicine five-element identification acupuncture on the basis of the above mentioned treatment,and the clinical effects,the scores on the scales[(Autism Treatment and Evaluation Scale(ATEC),Children's Autism Rating Scale(CARS),Autism Behavioral Scale(ABC)],serological indexes[tissue-type plasminogen activator(t-PA)and plasminogen activator inhibitor-1(PAI-1)]of the two groups were compared.
The total effective rate of the observation group(97.78%,44/45)was higher than that(82.22%,37/45)of the control group and the difference was significant(P<0.05).The ATEC scores of both groups were reduced after one and three months of treatment(P<0.05),and the reduction wasmore significant in the observation group compared with that in the control group(P<0.05).CARSscore and ABC score were reduced in both groups after one and three months of treatment(P<0.05),and the reduction was more significant in the observation group compared with that in the controlgroup(P<0.05).After one and three months of treatment,t-PA increased and PAI-1 decreased in both groups(P<0.05),and compared with those in the control group,t-PA increased more significantly and PAI-1 decreased more significantly in the observation group(P<0.05).
After the children diagnosed with autism were treated with the combination of ABA training and traditional Chinese medicine five-element identification acupuncture,the therapeutic effect was remarkable.The treatment could effectively reduce the children's clinical symptoms,improve their serological indexes and promote the recovery of the children.
To explore the clinical effect of ultrasound-guided needle knife dissection combined with lumbar inclined plate method in the treatment of gluteal epithelial nerve compression syndrome based on the theory of“bone alignment and tendon flexibility”.
Sixty patients with gluteal epithelial nerve compression syndrome who received treatment in the Orthopedic Department of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from January 2023 to January 2024 were selected as the study subjects.Using the random number allocation method,the patients were randomly divided into a control group(30 cases)and an experimental group(30 cases).The control group was treated with ultrasound-guided needle knife dissection,while the experimental group was treated with a combination of ultrasound-guided needle knife dissection and lumbar inclined plate dissection under the guidance of the“bone alignment and tendon flexibility”theory.The treatment period for both groupswas 4 weeks.After treatment,the clinical efficacy,Visual Analog Scale(VAS)score,Oswestry Disability Index(ODI)score,shear wave Young'smodulus values of the lumbar multifidus and psoasmajor muscles,and the changes in surface electromyography were compared between the two groups.
Compared with the control group,the experimental group had a higher clinical total effective rate after 4 weeks of treatment,but there was no statistically significant difference in the total effective rate between the two groups(P>0.05).Compared with those before treatment,VAS scores and ODI scores in both groups showed a decreasing trend after treatment and 4 weeks follow-up(P<0.05).Compared with those of the control group,the VAS score and ODIscore of the experimental group were lower after treatment and 4 weeks follow-up(P<0.05).Compared with those before treatment,the shearwave Young'smodulus values of the bilateral multifidus and lumbar muscles in the experimental group showed a decreasing trend after treatment and 4 weeks follow-up(P<0.05).Compared with those before treatment,there was no statistically significant difference in the shearwave Young'smodulus values of the bilateral multifidus and lumbar muscles in the control group after treatment and 4 weeks follow-up(P>0.05).Compared with the control group,the shearwave Young'smodulus values of the bilateral multifidus and lumbar muscles in the experimental group were lower after treatment and 4 weeks follow-up(P<0.05).Compared with those before treatment,the average amplitude of electromyography on both sides of the multifidus and lumbar muscles in the experimental group showed an increasing trend after treatmentand 4 weeks follow-up(P<0.05).Compared with those before treatment,there was no statistically significant difference in the average amplitude of surface electromyography of the multifidus and psoasmajormuscles in the control group after treatmentand 4 weeks follow-up(P>0.05).Compared with those in the control group,the average amplitude of surface electromyography of the multifidus and psoasmajor muscles in the experimental group was higher after treatment and 4 weeks follow-up(P<0.05).
The combination of ultrasound-guided needle knife dissection method and lumbar inclined plate method based on the concept of“bone alignment and tendon flexibility”can significantly improve the short-term and long-term clinical effects of treating gluteal epithelial nerve compression syndrome,with advantages such as high safety,minimal trauma and rapid recovery.
This study aims to explore the potential categories of five pattern personalities and analyze the differences of each category on the Big Five Personality.
A total of 963 volunteers were recruited to participate in the study.The survey was conducted using the Five Pattern Personalities Inventory and Big Five Personality Inventory.The latent categories of five pattern personalities were analyzed using latent profile analysis.
1)It was found that there were five latent categories of five pattern personalities:“low Yang-low Shaoyin-high Taiyin group”(12.56%),“low Yang-high Yin group”(27.73%),“high Yang-high Shaoyin low Taiyin group”(37.49%),“high Yang-high Yin group”(5.93%),“high Yanglow Yin group”(16.34%).2)The five latent categories of five pattern personality exhibited significant differences in each dimension of the Big Five Personality(P<0.001).The“low Yang group”(categories 1 and 2)demonstrated significantly lower levels of openness,extroversion and agreeableness compared to the“high Yang group”(categories 3 and 5)(P<0.001),while scoring higher on neuroticism than the“high Yang group”.Additionally,the rigor score for the“high Yang-high Shaoyin low Taiyin group”was significantly higher than other groups,whereas it was lower for the“low Yang-low Shaoyin high Taiyin group”.Furthermore,extraversion and agreeableness scores were lower for“high Yang-high Yin group”compared to“high Yang group”but higher than those for“low Yang group”;neuroticism scores were lower than those for“low Yang group”but higher than those for“high Yang group”as well.
There are five potentially categories of five pattern personalities.These different latent categories were significantly different on the Big Five Personality.
In this research,the lightweight deep learning YOLOv10 object detection algorithm is harnessed to develop an efficient algorithm for detecting Chinese herbal medicines on mobile devices,furnishing an intelligent and high-performance technical solution for the detection of Chinese herbal medicines in scenarios such as cultivation production,quality assessment,educational popularization and automated dispensing.A dataset for target detection of 31 commonly used Chinese herbal medicines is constructed,comprising a total of 6900 images.To enhance the multi-scale detection capability and detection efficiency of the model,the Ghost Convolution(Ghost Convolution,Ghost Conv)lightweight convolution and the weighted bidirectional feature pyramid module(Bidirectional Feature Pyramid Network,BiFPN)are incorporated,and an improved lightweight model for Chinese herbal medicine detection,namely YOLOv10n-GB,is proposed.The algorithm is then employed to conduct training,testing,analysis and mobile terminal deployment tests on the image samples within the dataset.The improved model exhibits2.27 M(Million)parameters,6.4 G(Giga)computational complexity,and an m AP50 value of0.947.In comparison with YOLOv10n,the parameter count is reduced by 1.2%,the computational load is decreased by 4.5%,and the mean average precision 50(mAP50)is augmented by 1.8%.The average frame rate of the model detection on the mobile terminal reaches 8.1Frames Per Second(FPS).When contrasted with other lightweight algorithms such as YOLOv5n and YOLOv8n,YOLOv10n-GB demonstrates the lowest floating-point computational cost and higher detection accuracy.The YOLOv10n-GB algorithm has accomplished the task of efficient detection of Chinese herbal medicines on mobile terminals,paving the way for novel ideas in establishing a portable and real-time detection scheme for Chinese herbal medicines.
As an important part of traditional Chinese medicine,pediatric Tuina plays a unique role in the prevention and treatment of children's diseases.However,the terminology for acupoints and techniques are diverse,and the national standards for the above terms need to be improved,which affects the overall development of the discipline of pediatric Tuina.Therefore,it is urgent to carry out the standardization of pediatric Tuina terminology.This article discussed the current situation of pediatric Tuina terminology standardization,the importance of terminology standardization and suggestions,in order to promote the standardized,scientific and international development of pediatric Tuina.
To investigate the efficacy and safety of Sanhuangtangshenkang(三黄糖肾康)combined with Dapagliflozin in the treatment of Qi deficiency and blood stasis type of early diabetic nephropathy(DN).
A randomized,double-blind and placebo-controlled clinical trial was conducted involving 120 patients from the Endocrinology and Nephrology Departments at Taizhou Hospital of Traditional Chinese Medicine from June 2021 to June 2023.The participants were allocated into two groups.The experimental group(60 patients)received standard care augmented with Sanhuangtangshenkang and Dapagliflozin,while the control group(60 patients)was treated with standard care plus placebo granules and Dapagliflozin.The duration of treatmentwas 12 weeks.The primary endpoints included the efficacy of treatment,the renal function,the inflammatory markers,the enhancement of traditional Chinese medicine(TCM)syndromes,and the frequency of adverse events.
A total of 117 patients were successfully enrolled,59 in the experimental group and 58 in the control group.The experimental group showed a significantly higher overall effective rate compared to the control group(98.30% versus70.68%,P<0.05).Biochemical indicators such as the urine albumin-to-creatinine ratio(UACR),24-hour urinary microalbumin(UMA)and 24-hour urinary protein were significantly improved in the experimental group compared to those in the control group after 12 weeks of treatment(P<0.05).Inflammatory markers including serum amyloid A(SAA),interleukin-6(IL-6),C-reactive protein(CRP)and homocysteine(Hcy)also showed more significant reductions in the experimental group,especially after 12 weeks of treatment(P<0.05).The improvements in renal function and other biochemical indicators,such as glycated hemoglobin(HbA1c),estimated glomerular filtration rate(eGFR)and total cholesterol(TC),were also notably better in the experimental group(P<0.05).TCM symptom scores further confirmed the improvement in various indicators in the experimental group after treatment(P<0.05).Although there was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).The experimental group exhibited a lower rate of adverse reactions(3.38%)compared to the control group(8.62%).
The combination of Sanhuangtangshenkang with Dapagliflozin is highly effective and safe for improving renal function,glycemic control and TCM syndromes in patients with early-stage DN characterized by Qi deficiency and blood stasis,demonstrating both enhanced safety and superior efficacy.
Neurodegenerative diseases(NDDs)are a complex group of conditions caused by progressive degeneration and dysfunction of cells and tissues in the central nervous system.The pathogenesis is intricate,and they are often chronic and difficult to cure,with no effective treatments currently available.Recent studies have shown that Chuanxiong(Chuanxiong Rhizoma),a traditional Chinese medicinal herb,exhibits a wide array of pharmacological effects.The main components of Chuanxiong(Chuanxiong Rhizoma)possess advantages in treating NDDs throughmulti-targetandmulti-pathwaymechanisms.This article reviewed the latest research advancements in the field of Chuanxiong(Chuanxiong Rhizoma)application to NDDs,primarily Parkinson's disease(PD),Alzheimer's disease(AD)and epilepsy.It summarized the use of Chuanxiong(Chuanxiong Rhizoma)and its compound formulations in the treatment of NDDs over recent years.The article particularly delved into the pharmacological effects of its active ingredients,including ferulic acid,tetramethylpyrazine(TMP),vanillic acid and ligustilide,in terms of their anti-inflammatory,antioxidant,anti-apoptotic,neurotoxicity-reducing,immunomodulatory and mitochondrial function-improving properties.This review served as a theoretical foundation for the future development of natural drugs derived from Chuanxiong(Chuanxiong Rhizoma)for the prevention and treatment of NDDs.
To observe the clinical efficacy of Wangbi Capsule(尪痹胶囊)in the treatment of dampness-heat blocking collateral type of rheumatoid arthritis and its effects on serum granulocyte-macrophage colony-stimulating factor(GM-CSF),tumor necrosis factor-α(TNF-α)and CD4+T cell subsets.
Ninety-eighty patients with rheumatoid arthritis treated in the Rheumatology and Immunology Department of the hospital from June 2020 to June 2023 were selected as the study objects,and the above patients were divided into control group and observation group with 49 cases in each group by random number table method.The control group was given leflunomide orally,and the observation group was given Wangbi Capsule on the basis of the control group.The clinical efficacy,TCM syndrome score and adverse reactions,the degree of joint pain and the levels of serum inflammatory factors before and after treatment were compared between two groups.
The effective rate of the control group was 79.59%,and that of the observation group was 93.88%.Compared with that of the control group,the effective rate of the observation group was significantly increased(P<0.05).There was no significant difference in TCM syndrome scores between the two groups before treatment(P>0.05).After treatment,the levels of morning stiffness,joint flexion and extension,fever,joint swelling pain and heat in the observation group were significantly decreased compared with those in the control group(P<0.01).Before intervention,there was no significant difference in ultrasound scores between the two groups(P>0.05).After the intervention,the ultrasound scores in the observation group were significantly higher than those in the control group(P<0.05).Before intervention,there was no significant difference in the degree of joint pain between the two groups(P>0.05).Compared with those of the control group,visual analog scale(VAS)score and disease activity score 28(DAS28)score of the observation group were significantly decreased after treatment(P<0.01).There was no significant difference in serum inflammatory factors between the two groups before intervention(P>0.05).After the intervention,the levels of erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),rheumatoid factor(RF),GM-CSF and TNF-αin the observation group were significantly decreased compared with those in the control group(P<0.01).During the intervention,the main adverse reactions of all patients were gastrointestinal discomfort,hemocytopenia,elevated aminotransferase and skin allergy,and there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).
Wangbi Capsule combined with leflunomide has a good clinical effect in the treatment of moisture-heat blocking collateral type of rheumatoid arthritis,which can alleviate the joint pain and dysfunction,improve the jointultrasound status and inhibit the inflammation,without increasing the adverse reactions.
To establish the infrared fingerprint spectra of standard decoctions of Xiangfu(Cyperi Rhizoma)and its processed products,and quickly identify the standard decoctions of Xiangfu(Cyperi Rhizoma)and its processed products.
Infrared fingerprint spectra were established for the decoctions of Xiangfu(Cyperi Rhizoma),wine-processed Xiangfu(Cyperi Rhizoma),vinegar-processed Xiangfu(Cyperi Rhizoma)and four-processed Xiangfu(Cyperi Rhizoma).The differences among the average infrared spectra of the decoctions of Xiangfu(Cyperi Rhizoma),wine-processed Xiangfu(Cyperi Rhizoma),vinegar-processed Xiangfu(Cyperi Rhizoma)and four-processed Xiangfu(Cyperi Rhizoma)were analyzed using OMNIC 9.2 software.The common peaks of Xiangfu(Cyperi Rhizoma)and its processed product decoctions were identified using Spectrum forWindow 3.02 software and the relative peak heights were calculated.The differences among the processed Xiangfu(Cyperi Rhizoma)decoctions were compared using principal component analysis,orthogonal partial least squares-discriminant analysis and clustering analysis.
A total of 12 common peaks were identified and standardized for the decoctions of Xiangfu(Cyperi Rhizoma),vinegar-processed Xiangfu(Cyperi Rhizoma),wine-processed Xiangfu(Cyperi Rhizoma)and four-processed Xiangfu(Cyperi Rhizoma)using baseline correction and normalization.The differences were obvious in the 1700-1000 cm-1 waveband,and fourmain contribution wavebands were selected,including2929 cm-1,1053 cm-1,997 cm-1 and 1639 cm-1.The processed Xiangfu(Cyperi Rhizoma)decoctionswere all clustered into four categories through analysis.
There are obvious differences among the decoctions of Xiangfu(Cyperi Rhizoma),vinegar-processed Xiangfu(Cyperi Rhizoma),wine-processed Xiangfu(Cyperi Rhizoma)and four-processed Xiangfu(Cyperi Rhizoma),and they can be quickly identified using infrared spectroscopy.The method is fast,effective and accurate.
To investigate the effect of Zijinlong Tablets(紫金龙片)combined with intravenous immunoglobulin in the treatment of lower respiratory tract infection in the elderly.
Totally 302 elderly patients with lower respiratory tract infections admitted to the hospital from March 2021 to March 2023 were selected and randomly grouped,each with 151 cases.Based on conventional treatment,the control group was given intravenous immunoglobulin,and the study group received Zijinlong Tablets combined with intravenous immunoglobulin.Then the clinicalefficacy,ratio of forced expiratory volume in the firstsecond to forced vital capacity(FEV1/FVC),peak expiratory flow(PEF),maximum voluntary ventilation(MVV),arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2),interleukin-6(IL-6),C-reactive protein(CRP),interleukin-1(IL-1),procalcitonin(PCT),immunoglobulin-(Ig)A,IgG,IgM and T-lymphocyte subsets(CD3+,CD4+,CD8+)were compared.
The study group reported a higher overall efficacy rate than the control group(93.38% vs85.43%,P<0.05).An increase in PEF,MVV and FEV1/FVC were observed in all patients after treatment,and the increase was more notable in the study group than those in the controlgroup(P<0.05).An elevation in PaO2 and a decrease PaCO2 were detected in all patients,and both improvements were more remarkable in the study group than those in the control group(P<0.05).After treatment,the levels of IL-6,CRP,IL-1 and PCT showed a decrease in all patients,and the three parameters were all lower in the study group than those in the control group(P<0.05).The levels of IgA,IgG and IgM demonstrated an increase in all patients,and were all larger in the study group than those in the control group(P<0.05).An elevation in CD3+and CD4+and a decrease CD8+were found in all patients,and both improvements were more obvious in the study group than those in the control group(P<0.05).
The application of Zijinlong Tablets combined with intravenous immunoglobulin in the treatment of lower respiratory tract infection in the elderly can effectively improve the pulmonary function and arterial blood gas indexes,attenuate the cellular inflammatory response,ameliorate the body immune function and promote the recovery of the patients.