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  • Jun SHI, Zhi-hao GE, Ya-ting REN, Su-fang WANG
    Modern Preventive Medicine. 2024, 51(12): 2253-2261.
    Objective

    To examine the correlation between body composition and insulin resistance (IR) within the general population of different genders.

    Methods

    The data for this study were sourced from the Hefei area data of the Chinese Residents Cardiovascular Disease and Risk Factors Monitoring Project conducted in 2021, with a total of 1 144 subjects being included,including 568 males and 576 females. The ratio of triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) was used as an alternative indicator of insulin resistance. A chi-square test was employed to analyze the association between body composition metrics—such as body mass index (BMI), percent body fat (PBF), percent body muscle (PBM), visceral fat area (VFG), and waist circumference (WC)—and the TG/HDL-C ratio. Logistic regression analysis was used to identify the factors influencing body composition in individuals with a TG/HDL-C ratio exceeding the tangent point value. The dose-response relationship between body components and the TG/HDL-C ratio was explored using restricted cubic splines, a statistical method that allows for the examination of nonlinear relationships.

    Results

    The positive detection rate of IR (the rate of TG/HDL-C above the cut point value) was 15.85% in men and 4.69% in women.After adjusting for confounding factors, logistic regression analysis showed that compared with the control group, the risk of IR in the male population was 5.58 times in the obese group (OR=5.58, 95%CI:1.98-15.72), PBF was 7.90 times in the third quartile (OR=7.90, 95%CI:1.68-37.15), the fourth quartile of PBF was 8.20 times (OR=8.20, 95%CI:1.75-38.40), and the third quartile of PBM was 0.27 times (OR=0.27, 95%CI:0.10-0.71), the PBM was 0.09 times in the fourth quartile group (OR=0.09, 95%CI:0.02-0.44), 3.11 times in the group with high VFG (OR=3.11, 95%CI:1.45-6.68), and 4.28 times in the group with higher VFG (OR=4.28, 95%CI:1.45-12.64). Abdominal obesity was 2.21 times (OR=2.21, 95%CI:1.08-4.56). In the female population, the risk of IR was 6.61 times in the obese group (OR=6.61, 95%CI:1.08-65.66) and 8.52 times in the higher VFG group (OR=8.52, 95%CI: 1.90-70.86) (P<0.05). The limited cubic spline showed that BMI, PBF, PBM, VFG, WC had dose-response relationship and approximate linear relationship with TG/HDL-C.

    Conclusion

    The body composition of community residents is closely associated with the risk of insulin resistance. Individuals who are obese or have high levels of visceral fat are at greater risk for insulin resistance. To mitigate this risk, it is imperative to reinforce lifestyle interventions that prioritize maintaining a higher percentage of muscle mass.

  • Xiao-yu DONG, Huai-zhi CHENG, Ling-xiao GAO, Dong-quan CHEN, Jie-sen SHANG, Ruo-tong TIAN, Bin GUO
    Modern Preventive Medicine. 2024, 51(12): 2215-2220.
    Objective

    To understand the impact and effect value of basic medical insurance on the health status of children in China, and to propose corresponding countermeasures and suggestions.

    Methods

    Based on the data from the Chinese Family Panel Studies in 2016 and 2020, this study examined the extent to which basic medical insurance impacts children’s health using the Propensity-Score-Matching and Difference-in-Difference models.

    Results

    The findings indicated that basic medical insurance could promote the health status of children by 4.9%(β=0.049,SE=0.028). However, the mediating effects of reducing health costs and improving health service utilization were found to be insignificant. Moreover, the study revealed that the health status of preschool children, girls, rural areas, western regions, and low-income families can be improved by 9.1%(β=0.091,SE=0.038), 7.8%(β=0.078,SE=0.043), 9.3%(β=0.093,SE=0.041), 12.0%(β=0.120,SE=0.051), and 9.3%(β=0.093,SE=0.055) respectively.

    Conclusion

    This study concludes that basic medical insurance plays a positive role in enhancing children’s health. Therefore, it is crucial to continuously strengthen the basic medical insurance system and reinforce the multi-tiered healthcare security framework. Attention should also be given to ensuring fairness for girls and children in rural and western areas, in order to fully protect children’s health.

  • Yue GONG, Ming-xia CHEN, Ze-hui FAN, Ze-hua HUANG, Tian-li XIAO, Xue-long FAN, Chan-juan ZHENG, Yi-de YANG
    Modern Preventive Medicine. 2024, 51(12): 2182-2187.
    Objective

    The aim of this study is to test the reliability and validity of the Chinese version of CP-Q among college students.

    Methods

    The English version of the CP-Q was translated, back-translated following the Brislin model, and cultural adaptation was performed to develop the Chinese-version CP-Q.The reliability, validity and feasibility of the questionnaire were evaluated by investigation of questionnaires offline and electronic questionnaires online.

    Results

    A total of 658 participants were investigated with 593 valid questionnaires obtained, the total effective rate was 90.1%.Subjects finished the Chinese-version CP-Q and Pittsburgh Sleep Quality Index (PSQI); Munich Chronotype Questionnaire (MCTQ) and 24h dietary recalls. Moderate to strong correlations were observed in the sleep/wake schedules between the Chinese-version CP-Q, PSQI and MCTQ, both for work/study days and free days, the highest was the free day sleep time r=0.922(P<0.001).The correlations between sleep, wake, first eating event, lunch time and last eating event in work/study days and free days with the same variables in the 24h recall showed r=0.441-0.659 (P<0.05), in addition to the lunchtime in free days (r=287, P=0.076). A total of 7 items among the 17 variables in the Chinese-version CP-Q evaluated in the test and retest phases presented intraclass correlation coefficients ≥0.75.

    Conclusion

    The Chinese-version CP-Q has good reliability and validity and could reflect the real situation of eating time and sleeping time. The questionnaire can be used to assess the status of one’s chrononutrition.

  • Fei CHENG, Lan GAO, Lian-xin TIAN, Xue LI, Qiu-yun WANG
    Modern Preventive Medicine. 2024, 51(12): 2282-2286.
    Objective

    To analyze the characteristics of suspected adverse events following immunization (AEFI) in Guiyang City from 2014 to 2023, to evaluate the safety of immunization in Guiyang City, and to provide guidance for improving AEFI monitoring.

    Methods

    Collect AEFI data and vaccine immunization data in Guiyang City from 2014 to 2023 through the “National Immunization Planning Information System” and “Guizhou Province Immunization Planning Information Management System.” Use descriptive epidemiological methods to statistically analyze the epidemiological characteristics and reported incidence rates of AEFI in Guiyang City.

    Results

    From 2014 to 2023, Guiyang City reported a total of 4 498 cases of AEFI, with an average annual reported incidence rate of 14.63 per 100 000. The incidence rate was the highest in 2023 (1 358 cases, 42.43/100 000) and the lowest in 2015 (23 cases, 1.85/100 000). The reported incidence rate had a statistically significant difference among different years (χ2=3 638.04,P<0.001). Yunyan District reported the most cases (1 539 cases, 25.86/100 000), while Xifeng County reported the least cases (86 cases, 6.67/100 000), and the difference among different regions was statistically significant (χ2=890.10,P<0.001). The most cases were reported in November (588 cases, 24.7/100 000) and the least in February (136 cases, 8.37/100 000), and there was a statistically significant difference among different months (χ2=277.31,P<0.001). The male-to-female ratio was 1.10:1.00, with the highest reports in the age group ≤1 year (2 697 cases, 59.96%). The outcome was recovery or improvement in 96.47% of cases.

    Conclusion

    2014-2023 AEFI in Guiyang is mainly a general response and the vaccination safety is good. However, the work carried out in different places varies and the monitoring sensitivity needs to be further enhanced.

  • Zhi-yu CHEN, Zhen LIU, Jia-yuan ZHOU, Yu-yang GAO, Wen-li XU, Li DAI, Wen-yan LI
    Modern Preventive Medicine. 2024, 51(12): 2121-2126.

    Multiple birth defects, also known as multiple congenital anomalies (MCAs), are defined as the simultaneous presence of defects in two or more different systems, organs or tissues in the same individual. MCAs account for 20% to 30% of all children with birth defects and have become an important public health issue in the prevention and control of birth defects. MCAs can occur as random events or as etiologically related patterns of abnormal. Identifying MCAs patterns can provide important clues for revealing the underlying aetiology, elucidating the mechanism, predicting the development trend, and formulating strategiesforprevention and treatment. Currently, there are many methods for assessing the pattern of MCAs, and each calculation method has its own advantages and disadvantages. In this study, we reviewed five commonly used statistical analysis methods for evaluating the pattern of MCAs, including the proportion method, multiple regression analysis, cluster analysis, log-linear analysis, and O/E (Observed/Expected) ratio. Moreover, we elaborated on their applications, strengths, and limitations in the birth defects surveillance system. Given the large birth defects surveillance system and rich data resources in China, which provides good conditions for MCAs research, the current review of the MCAs analysis methods is of great significance for making full use of these resources to conduct related research.

  • Ting YANG, Ge-yao ZHOU, Yuan-fen CHENG, Si-yin CHEN, Dan LI, Juan-hua YANG, Yu CAO
    Modern Preventive Medicine. 2024, 51(12): 2228-2234.
    Objective

    To explore the relationship and mechanism of stress perception and loneliness among emotional intelligence and life satisfaction among master’s students, and to provide reference basis for promoting the mental health development of graduate students.

    Methods

    A total of 728 graduate students from 6 universities were selected by stratified cluster random sampling and investigated by emotional intelligence, loneliness, stress perception and life satisfaction scale. SPSS 25.0 was used to conduct independent sample t-tests, analysis of ANOVA, and Pearson correlation analysis on the data. A structural equation model was bulit by using AMOS 26.0 software and evaluated.

    Results

    Emotional intelligence was positively correlated with life satisfaction (r=0.423, P<0.01). There was a negative correlation between perceived stress and loneliness, life satisfaction, and emotional intelligence (r=-0.519, -0.440, -0.536, -0.505,P<0.01). There was a positive correlation between perceived stress and loneliness (r=0.568, P<0.01). Emotional intelligence can not only directly predict life satisfaction, but also indirectly through stress perception and loneliness. The mediation effect value of stress perception was 0.227 accounting for 42.5% of the total effect,and the mediation effect value of loneliness was 0.026, accounting for 4.9% of the total effect. The effect value of emotional intelligence and life satisfaction was 0.029, accounting for 5.4% of the total indirect effect.

    Conclusion

    Emotional intelligence can affect the life satisfaction of master’s students through the mediating or chain mediating effect of stress perception and loneliness, which provides a theoretical basis for improving the quality of life and mental health of master’s students.

  • Xiao-feng GAO, Min LIU, Yun DUAN
    Modern Preventive Medicine. 2024, 51(12): 2210-2214.
    Objective

    To explore the status and influencing factors of health poverty among the elderly in rural areas of Sichuan in the post poverty alleviation era.

    Methods

    By using the method of multi-stage sampling, a questionnaire survey was conducted among 606 rural elderly persons in Sichuan from July to August, 2022. Chi-square test and multivariate logistic regression analysis were used to explore the influencing factors of health poverty.

    Results

    Among the 606 persons, 167 (27.6%) were in health poverty.The results of multivariate analysis showed that age(OR=1.655, 95%CI: 1.250-2.191), number of chronic diseases (OR=1.864, 95%CI: 1.510-2.301) and physical function limitation (OR=1.890, 95%CI: 1.353-2.640) were the risk factors, while the number of daughters (OR=0.739, 95%CI:0.593-0.920) and labor intensity in the past year (OR=0.498, 95%CI: 0.343-0.722) were protective factors for health poverty in the rural elderly.

    Conclusion

    The rural elderly in Sichuan still have a high risk of health poverty, especially the elderly who are aged, suffer from multiple chronic diseases, have serious disability, have little labor intensity, and have few daughters are the high-risk groups of health poverty, which needs to be paid attention to.

  • Peng-yue SHEN, Wen-qiang ZHANG, De-qin HUANG, Lin HE, Xia JIANG, Ben ZHANG
    Modern Preventive Medicine. 2024, 51(12): 2146-2151.
    Objective

    To evaluate the causal relationships between lipids (low-density lipoprotein cholesterol, high-density lipoprotein cholesterol [HDL-C], triglyceride [TG], apolipoprotein A-I [ApoA-I], apolipoprotein B) and non-alcoholic fatty liver disease (NAFLD) through a two-sample Mendelian randomization (MR) study.

    Methods

    Summary datasets of genome-wide association studies of lipids and NAFLD in European ancestry were leveraged, and single nucleotide polymorphisms associated with lipids were selected as instrumental variables. Several univariable MR analyses were conducted, including inverse-variance weighting method, MR-Egger regression, weighted median estimation, MR pleiotropy residual sum and outlier method. A multivariable inverse-variance weighting method was further used to evaluate the independent causal effect of lipids on NAFLD.

    Results

    Univariable inverse-variance weighting MR showed that genetically predicted higher HDL-C (OR=0.774, 95%CI: 0.708-0.845, P<0.001) and ApoA-I (OR=0.878, 95%CI: 0.796-0.968, P=0.009) were associated with a lower risk of NAFLD, while genetically predicted higher TG (OR=1.323, 95%CI: 1.201-1.458, P<0.001) was associated with a higher risk of NAFLD. The causal effects of HDL-C and TG on NAFLD remained consistent in multivariable MR when adjusting for other lipids, body mass index, and type-2 diabetes.

    Conclusion

    Our study supports a putative causal relationship between HDL-C, TG, and NAFLD.

  • Wen-ying ZHANG, Bin CAO, Xiao-tong ZHANG, Meng-meng LIU, Lin-lin JIANG, Ting-ting LIU, Feng-jing SONG, Cheng-yu CHEN, Lin FAN, Xu HAN, Chao WANG, Li LI, Hang LIU, Yi-ming SUN, Bin LUO, Xian-liang WANG
    Modern Preventive Medicine. 2024, 51(11): 1956-1961.

    Objective To explore the pollution level and spatiotemporal characteristics of indoor dust di (2-ethylhexyl) phthalate(DEHP) in daily life and the influencing factors of potential family environment and personal living habits, providing scientific basis for the prevention and control of DEHP pollution in indoor dust. Methods Considering the factors of climate, economy and pollution level, household dust samples were collected and investigated in 9 typical cities of Lanzhou, Luoyang, Panjin,Mianyang, Qingdao, Shenzhen, Shijiazhuang, Wuxi, and Xi’an. DEHP content in the treated dust samples was measured using gas chromatography-mass spectrometry (GC-MS). The Wilcoxon rank sum test was employed to examine differences in DEHP levels across various seasons, dominant wind directions, types of home decoration, and living habits. Multiple linear regression was used to identify factors influencing DEHP content in indoor dust. Results DEHP levels in indoor dust varied significantly with season and dominant wind direction in some cities (P<0.05). Specifically, Luoyang and Mianyang exhibited higher DEHP levels during the heating season compared to other periods, while Shenzhen and Shijiazhuang showed lower levels during the heating season (P<0.05). In Mianyang, the upwind areas had significantly higher DEHP levels than the downwind areas (P<0.05). Factors influencing household dust DEHP levels included PM2.5 (β=0.003, 95%CI: 0.001-0.005), PM10 (β=-0.003,95%CI: -0.005 to -0. 001), formaldehyde (β=3.626, 95%CI: 0.195-7.057), and per capita GDP (β=-0.072, 95%CI: 0.050-0.095). Conclusion DEHP is commonly found in indoor dust in daily life. Seasonal variations and wind direction affect its levels in different cities, though no consistent pattern of pollution characteristics is observed across the cities. Additionally,DEHP content in indoor dust may be influenced by temperature, PM10, xylene, computer use, carpet use, and indoor plant cultivation..

  • Miao GAO, Rong-ling PAN, Zi-xuan CHEN, Xin PENG, Guo-xiao LIANG, Jin-lin ZHONG, Yu-qian MO, Jin-lin DU, Zhi-gang HUANG
    Modern Preventive Medicine. 2024, 51(11): 2055-2060.

    Objective To investigate whether there is a mediating effect of cognitive function between social participation and frailty. Methods Using the China Health and Retirement Longitudinal Survey (CHARLS) database, three rounds of survey data in 2011, 2013, and 2015 were selected for the study. The data in 2011 were the baseline data, and the ID number was used to match the participants in the follow-up in 2013 and 2015. A total of 3 139 people were enrolled in this cohort study. Cox regression model and simple mediating effect model were used to analyze the relationship among social participation, cognitive function, and frailty. Results A total of 259 patients had frailty during the follow-up period. The results of multivariate Cox regression model adjusting social demography and lifestyle showed that social participation (HR=0.641, 95%CI: 0.496-0.829)and cognitive function (HR=0.952, 95%CI: 0.928-0.977) were associated with frailty. The results of the intermediary model with relevant covariates showed that cognitive function has a significant mediating effect between social participation and frailty. Conclusion Social participation and cognitive function are associated with frailty, and cognitive function has some mediating effect between social participation and frailty.