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To analyze the characteristics of suspected adverse events following immunization (AEFI) in Guiyang City from 2014 to 2023, to evaluate the safety of immunization in Guiyang City, and to provide guidance for improving AEFI monitoring.
Collect AEFI data and vaccine immunization data in Guiyang City from 2014 to 2023 through the “National Immunization Planning Information System” and “Guizhou Province Immunization Planning Information Management System.” Use descriptive epidemiological methods to statistically analyze the epidemiological characteristics and reported incidence rates of AEFI in Guiyang City.
From 2014 to 2023, Guiyang City reported a total of 4 498 cases of AEFI, with an average annual reported incidence rate of 14.63 per 100 000. The incidence rate was the highest in 2023 (1 358 cases, 42.43/100 000) and the lowest in 2015 (23 cases, 1.85/100 000). The reported incidence rate had a statistically significant difference among different years (χ2=3 638.04,P<0.001). Yunyan District reported the most cases (1 539 cases, 25.86/100 000), while Xifeng County reported the least cases (86 cases, 6.67/100 000), and the difference among different regions was statistically significant (χ2=890.10,P<0.001). The most cases were reported in November (588 cases, 24.7/100 000) and the least in February (136 cases, 8.37/100 000), and there was a statistically significant difference among different months (χ2=277.31,P<0.001). The male-to-female ratio was 1.10：1.00, with the highest reports in the age group ≤1 year (2 697 cases, 59.96%). The outcome was recovery or improvement in 96.47% of cases.
2014-2023 AEFI in Guiyang is mainly a general response and the vaccination safety is good. However, the work carried out in different places varies and the monitoring sensitivity needs to be further enhanced.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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