To explore the focuses and potential issues of the current children’s health policy system for informing policy decision-making.

This study constructed a two-dimensional analysis framework of policy tools-stakeholders, and the content analysis method was used to quantitatively analyze 36 children’s health policies in China.

The study coded a total of 542 nodes for policy tools. The environment-based policy tools, supply-based policy tools, and demand-based policy tools accounted for 43.7%, 36.5%, and 19.7%, respectively. There were 464 nodes of stakeholders, and administrative agencies, hospitals, primary health care facilities, children and families, health care workers, and other agencies accounted for 61.4%, 13.6%, 3.7%, 8.0%, 3.2% and 10.1%, respectively.Two-dimensional analysis revealed that children and families focused on demand-based policy tools (16 out of 34 nodes), primary healthcare/hospitals/health care providers focused on supply-based policy tools (20 out of 26, 41 out of 85, and 10 out of 15 nodes), and administrative agencies focused on environmental policy tools (170 out of 351 nodes).

The continuous launch of children’s health policies indicates that the government ensures the principle of Children First. However, the current policies on the supply of children’s health services, the training of pediatric personnel, and PHC are inadequate. The government should focus on improving the supply of children’s healthcare services, expanding the pediatric workforce, and constructing an integrated service system for children.

To analyze the trend of health-care seeking delay and influencing factors among pulmonary tuberculosis patients and provide a reference basis for prevention and control measures in Yantai.

The current status and trend of health-care seeking delay among pulmonary tuberculosis patients in Yantai from 2012 to 2021 were described. Additionally, multivariate logistic regression was employed to analyze the influencing factors of health-care seeking delay.

From 2012 to 2021, the median of health-care seeking days was 28 (10, 61) days. The health-care seeking delay rate was 66.47% and exhibited an upward trend (, P<0.001). Multivariate logistic regression analysis revealed that compared with the age group over 61 years old, the following factors were associated with reduced risk for delayed treatment: individuals under 20 years old (OR=0.65, 95% CI: 0.56-0.75), aged 21-40 years (OR=0.80, 95% CI: 0.74-0.88), serving public places and businesses (OR=0.66, 95% CI: 0.49-0.90), children and students (OR=0.73, 95% CI: 0.61-0.87), employees of enterprises and institutions (OR=0.80, 95% CI: 0.66-0.97), engaged in other physical labor (OR=0.83, 95% CI: 0.74-0.92), and belonging to the native population (OR=0.68, 95% CI: 0.60-0.78). On the other hand, the age group of 41-60 years old (OR=1.12, 95% CI: 1.03-1.22), symptomatic treatment (OR=4.30, 95% CI: 3.63-5.10), referral (OR=3.40, 95% CI: 2.87-4.03), follow-up (OR=5.59, 95% CI: 4.69-6.66), and pathogen positive results (OR=1.33, 95% CI: 1.24-1.43) were identified as risk factors for delayed treatment.

The health-care seeking delay rate among tuberculosis patients showed an upward trend from 2012 to 2021 in Yantai. Medical institutions should pay attention to the wrinkly or elderly, passive detection, and pathogen positive patients regarding the health-care seeking delay.

To explore the mediating effect of pain condition between the number of chronic diseases and handgrip strength and the moderating role of sleep quality among middle-aged and elderly people over 45 years old in China.

Based on the data from the 2015 China Health and Elderly Tracking Survey, model 4 and model 59 in the Process 4.1 program were used to analyze and construct the mediator model and the mediator model with moderation.

A total of 13 930 Chinese middle-aged and older adults were included after screening, with handgrip strength values of (30.81 ± 10.03), number of chronic diseases (1.33 ± 1.44), number of pain sites (1.60 ± 3.23), and sleep quality (2.98 ± 1.21). Chronic conditions inversely predicted handgrip strength (B=-0.212, P<0.001). Number of pain sites partially mediated the relationship between chronic conditions and handgrip strength (B=-0.177, P<0.001). Sleep quality moderated the first half of the mediating pathway (chronic diseases → pain conditions), and simple slope plots showed that the number of chronic diseases had a more significant effect on pain conditions in middle-aged and older adults with low sleep quality than in middle-aged and older adults with high sleep quality.

Chronic diseases can affect grip strength directly or indirectly through pain conditions, and sleep quality moderates the mediating effect of pain conditions. Reduced grip strength due to chronic diseases in middle-aged and older adults can be mitigated by reducing pain conditions and improving sleep quality.

To understand children’s parents’ cognition and behavior of antibacterial drugs, so as to provide reference for promoting rational use of antibacterial drugs in children, reducing bacterial drug resistance and adverse drug reactions.

From April 2022 to April 2023, 517 parents of pediatric inpatients at Pingshan District People’s Hospital in Shenzhen were surveyed on the cognition and behavior of antibacterial drug use. Descriptive analysis, univariate analysis and multiple linear regression analysis were used to explore the possible factors affecting parents’ cognition and behavior of rational use of antibiotics.

A total of 517 questionnaires were collected, of which 482 were valid, with an effective recovery rate of 93.23%. The scores of parents’ knowledge and practice on antibacterial drugs were (7.06±3.91) and (28.02±4.32), and the scoring rates were (44.11±24.46)% and (80.06±12.34)%, respectively. The cognitive score was positively correlated with senior high school or technical secondary school (β=0.180, 95% CI: 0.677-2.569), junior college (β=0.244,95% CI: 1.177-3.125), undergraduate degree or above (β=0.353, 95% CI: 2.035-4.333), and was negatively correlated with parents’ with medical background (β=-0.109, 95% CI: -2.800--0.371). The behavioral score was positively correlated with the mother (β=0.123, 95% CI: 0.358-2.198) and parents’ with medical background (β=0.090, 95% CI: -0.006-2.874).

The overall awareness of antimicrobial drugs among parents of children in this urban area is relatively low, and the score rate for rational use of antibiotics is relatively high. However, there are still some misconceptions. It is recommended that relevant departments should strengthen the education of antimicrobial knowledge to the public, strengthen the management of grassroots medical institutions and retail pharmacies, strictly regulate access channels, standardize medication behavior, and try to eliminate the hidden dangers of unreasonable use of antibiotics.

To investigate the incidence and influencing factors of mental disorders in people living with HIV/AIDS and to provide reference for clinical prevention of HIV associated mental disorders.

People living with HIV/AIDS who were diagnosed in our hospital from May 2017 to March 2023 were stratified randomly selected according to the year of admission. The first hospitalization records and laboratory test data from the medical record management systemwere reviewed and then relevant parameters were extracted as baseline data and were followed up regularly. Cox regression was used to analyze the influencing factors of HIV associated mental disorders.

A total of 503 people living with HIV/AIDS meeting the study criteria were included, 71 patients were diagnosed with mental disorders during follow-up, with an incidence of 14.1%. Multivariate analysis showed poor sleep (HR=3.813, 95% CI: 2.237-6.501), ART side effects (HR=1.740, 95% CI: 1.047-2.891), poor insight (HR=7.213, 95% CI: 4.277-12.163), abnormal CD4/CD8 cell ratio (HR=2.772, 95% CI: 1.246-6.163) and abnormal creatine kinase (HR=1.765, 95% CI: 1.086-2.871)were risk factors for HIV associated mental disorders.

People living with HIV/AIDS have a relatively high incidence of mental disorders within the first year of diagnosis, the influencing factors should be identified as early as possible when HIV/AIDS patients are diagnosed, and corresponding intervention plans should be formulated to prevent the occurrence and development of HIV associated mental disorders.

To explored the relationship between the Dietary Oxidative Balance Score (DOBS) and the risk of developing osteoporosis in patients with chronic kidney disease (CKD) based on data from the National Health and Nutrition Examination Survey (NHANES).

The study population was selected from CKD patients aged 40 years and above in a total of four survey cycles of NHANES 2007—2008, 2009—2010, 2013—2014, and 2017—2018, and the association between DOBS and the risk of developing osteoporosis in CKD patients was assessed using weighted logistic regression, with smoothed curve fitting demonstrating the dose-response relationship between the two and subgroup analyses based on age and gender.

A total of 2 281 participants were included in this study, and the fully adjusted model (Model 3) found that higher DOBS significantly reduced the risk of osteoporosis in CKD patients, with an OR of 0.400 (95% CI: 0.211-0.758) in the highest quartile group of DOBS (Q4) compared with Q1. Smoothed curve fitting revealed a negative linear dose-response relationship between DOBS and the prevalence of osteoporosis. Subgroup analysis revealed that the negative association between DOBS and osteoporosis was more significant in female and ≥65-year-old CKD patients, respectively.

In this study, we found that the relationship between DOBS and the risk of osteoporosis in CKD patients was linearly negatively correlated and showed gender and age differences, but further studies are needed to confirm this.

To explore the current situation of disease prevention and control ability and training needs of grassroots public health personnel in Luzhou, to provide a reference for improving the disease prevention and control ability of grassroots public health personnel in Luzhou.

A questionnaire survey was conducted on 1 075 people engaged in disease control work in township health centers, village clinics, and community health service centers (stations) in Luzhou City to analyze their disease prevention and control ability and influencing factors.

The average self-evaluation score of basic disease prevention and control ability skills of primary public health personnel in Luzhou City was 57.93±27.30 points, with a score rate of 46.72%. Among them, "prevention and control of chronic non-communicable diseases" had the highest score rate of 56.94%, and "prevention and control of endemic and parasitic diseases" had the lowest score rate of 37.75%. Among the survey respondents, 92.37% had participated in basic knowledge or skills training in disease control, and the proportion of those who chose "on-site guidance" as the desired form of training was the highest, at 80.74%. The results of multiple linear regression analysis showed that the factors affecting the ability of primary public health personnel in disease prevention and control were mainly female (t=-3.425, P=0.001), outside the establishment (t=3.322, P=0.001), not having participated in training in basic knowledge or skills of disease control (t=-6.119, P<0.001), professional background (non-medical t=-2.083, P=0.038) and professional background (non-medical t=-0.083, P=0.038).

The disease prevention and control ability of grassroots public health personnel in Luzhou City is relatively weak, with gender, professional background, establishment, and whether they have participated in training being the main influencing factors, requiring targeted training in relevant knowledge and skills.

To investigate the survival situation and influencing factors of patients receiving antiretroviral therapy (ART) in Jinjiang district, Chengdu, and to evaluate the effect of ART and optimize follow-up management mode.

The follow-up data of HIV/AIDS patients were collected from the National HHART reporting system during 2012-2022. Life table method was used to describe the survival status, and Cox proportion hazard regression model was used to identify the factors related to survival time.

A total number of 2 113 cases was enrolled, the average age of the study subjects was (38.65±15.65) years old, and the average survival time was 132.41 months. By the time of the follow-up observation was terminated, 71 cases died. The accumulated survival rates of 1, 3, 5 and 10 year after initiating ART were 97.86%, 96.78%, 96.43% and 95.73%, respectively. The multivariable Cox proportional hazards regression analysis indicated that the risk of death. The HR of 40-49 years, 50-59 years, and ≥60 years group were 4.233(95% CI: 1.608-11.139), 3.997(95% CI: 1.265-12.623), 19.994(95% CI: 7.424-53.846) relative to <30 years group, respectively. The HR of unmarried group was 3.359(95% CI: 1.495-7.546) relative to married group. The HR of interval time between diagnosis and treatment 31-60 days, 61-90 days group were 2.337(95% CI: 1.311-4.165), 3.430(95% CI: 1.608-7.319) relative to ≤30 days group. The HR of 200-349 cells/μl and ≥350 cells/μl baseline CD₄⁺T cells counts group were 0.262(95% CI: 0.135-0.509), 0.206(95% CI: 0.080-0.530) relative to <200 cells/μl group. The HR of related symptoms before treatment group was 2.088(95% CI: 1.051-4.148) relative to no related symptoms before treatment group.

The effect of patients receiving ART in Jinjiang District is remarkable. ART coverage should be extended, and corresponding follow-up management measures and intervention means should be developed according to the actual situation in Jinjiang District.

To explore the vitamin D nutritional status and influencing factors of primary and middle school students in poverty areas of Guizhou Province, and to provide scientific basis for the development of targeted nutritional improvement measures.

A total of 2,519 students from 4 primary and 4 middle schools in 9 key monitoring counties (districts) in Guizhou Province, where the Nutrition Improvement Program for Rural Compulsory Education Students was implemented in 2023, were selected for questionnaire surveys, physical examinations, and blood biochemistry tests using multistage cluster sampling methods. Multifactorial logistic regression was used to analyze the current status of vitamin D nutrition and its influencing factors.

The average vitamin D level of primary and middle school students in poverty areas of Guizhou Province was (22.59±6.66)ng/ml, and the rate of low vitamin D was 37.51%. The prevalence of low vitamin D among female students (46.17%) was higher than that of male students (29.11%), and the difference was statistically significant (χ²=78.213, P<0.001). There was a significant difference in the rate of low vitamin D among students in different regions (χ²=23.454, P<0.001), and the rate of low vitamin D tended to increase with age (χ²=44.905, P<0.001). The results of multifactorial logistic regression analysis showed that, compared with the corresponding reference group, ethnic minorities (OR=0.706, 95% CI: 0.590-0.844), physical activity ≥60 min/d (OR=0.791, 95% CI: 0.663-0.943), and living in the countryside (OR=0.747, 95% CI: 0.616-0.906) were protective factors for low vitamin D levels; obesity (OR=2.133, 95% CI: 1.390-3.272), female students (OR=2.238, 95% CI: 1.882-2.662), the 11-13 years old group (OR=1.849, 95% CI: 1.521-2.248) and the 14-17 years old group (OR=2.000, 95% CI: 1.576-2.539) were risk factors for low vitamin D levels.

High rates of low vitamin D among primary and middle school students in poverty areas of Guizhou Province require the development of personalized nutritional interventions to improve vitamin D nutritional status.

Toanalyze the application of CNN-BiLSTM combination model and intelligent algorithm optimization in the prediction and early warning of HFMD incidence and to discussthe optimization model for predicting the incidence of HFMD, so as to provide reference for relevant departments to formulate prevention and control measures.

The monthly incidence data of hand, foot and mouth disease in Shanxi Province from January 2009 to December 2019 and the year-end resident population data released by the Shanxi Statistical Yearbook 2008-2020 were collected from January 2009 to December 2019.The monthly incidence data of hand, foot and mouth disease in Shanxi Province from January 2009 to December 2019 were used as sample modeling data to construct the corresponding models in MATLAB 7.6 software, and the prediction effect of each model was compared, and the optimal model was selected according to the principle that the smaller the error value and the higher the accuracy.

By comparing the root mean square error and mean absolute error obtained by predicting the monthly incidence of foot and mouth disease of hand with different models, it can be seen that the CNN-BiLSTM model optimized based on intelligent algorithm is significantly better than the unoptimized CNN-BiLSTM combination model, that is, the values of RMSE and MAE of CNN-BiLSTM-PSO/GAPSO/SSA (1.943 3,1.309 7; 1.879 2, 1.240 2; 1.419 5, 1.169 1) is smaller than the corresponding CNN-BiLSTM model (2.066 3, 1.390 8), among which the CNN-BiLSTM-SSA combination model performs best.

The CNN-LSTM-SSA model has good predictive performance and accuracy in predicting the monthly incidence trend of HFMD, which can be used to predict the future incidence of HFMD in Shanxi Province.