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Benzene has clear carcinogenicity and can lead to leukemia, posing a serious threat to the occupational health of workers with benzene exposure. Exploring the mechanism of benzene induced hematotoxicity is of great significance for precise prevention and control of the health effects of benzene. With the continuous development of molecular biological methods, multiple forms of programmed cell death (PCD) have recently been discovered, and related research involves multiple fields. Some studies have reported that some PCD are related to the mechanism of benzene induced hematotoxicity. This article reviews relevant literature through platforms such as PubMed and CNKI, briefly elaborating on the molecular mechanisms of cell death programs such as apoptosis, autophagy, pyroptosis, and ferroptosis, and discussing the role and impact of reported forms of PCD in benzene induced hematotoxicity, in order to provide new directions and suggestions for in-depth research on the mechanism of benzene hematotoxicity from the perspective of PCD.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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