To understand the longitudinal association of adverse childhood experiences and self-control with mobile phone dependence among junior high school students, and to provide reference for the development of prevention and control measures.

Convenience sampling was used to select 863 junior high school students from 18 classes in 2 middle schools as the research subjects. The Childhood Adversity Questionnaire, Self-Control Scale, and Mobile Phone Dependence Index Scale were used as the survey tools. Two follow-up surveys were conducted in November 2023 (T1) and May 2024 (T2). SPSS 23.0 was used for independent sample t-tests, one-way ANOVA, paired sample t-tests, partial correlation analysis, and factor analysis. Mplus 8.3 software was used for cross-lagged analysis and mediation effect testing.

The partial correlation analysis revealed that both the adverse childhood experiences and self-control were statistically significantly correlated with the mobile phone dependence of junior high school students (r=-0.646-0.762, P<0.05). The cross-lagged model analysis indicated that the adverse childhood experiences at T1 could positively predict the mobile phone dependence at T2 (β=0.107, 95% CI: 0.050-0.164, P<0.05); the mediation model analysis showed that the mediating effect of the adverse childhood experiences on the influence of self-control on the mobile phone dependence of junior high school students was (β=0.019, 95% CI: 0.006-0.033, P<0.05).

Adverse childhood experiences could positively and indirectly affect mobile phone dependence through self-control among junior middle school students.

To analyze the current status and changing trends of ischemic stroke burden attributable to high LDL-C in China from 1990 to 2021. By integrating the prediction results for the next decade, this research offers actionable insights for designing evidence-based interventions targeting ischemic stroke prevention and management in China.

Data were obtained from the Global Burden of Disease Study (GBD) 2021 database and screened for Chinese regions, causes of ischemic stroke deaths, and high LDL-C risk factors. The disease burden was measured using indicators such as mortality and disability-adjusted life year (DALY) rates, and systematically analyzed the trends using the Joinpoint regression model. The autoregressive moving average (ARIMA) model was employed to predict the standardized mortality and standardized DALY rates of ischemic stroke attributable to high LDL-C in China from 2022 to 2031.

The overall trend of ischemic stroke rates attributable to high LDL-C in the Chinese population was declining between 1990 and 2021, with mean annual percentage changes (AAPC) of-0.42% (95% CI: -0.66%~-0.18%, P<0.05) and -0.46% (95% CI: -0.63%~-0.29%, P<0.05), with significant age and sex disparities observed. According to the ARIMA model, China’s standardized mortality and DALY rates linked to elevated LDL-C would decline to 15.01 per 100 000 population and 319.00 per 100 000 population, respectively, by 2031.

The disease burden of ischemic stroke attributable to high LDL-C remains substantial in China, and the interventions on LDL-C levels in the priority populations of men and elderly ischemic stroke patients should be reinforced, and prevention and control strategies as well as institutional support should be improved for the purpose of alleviating the disease burden of ischemic stroke more effectively.

To explore the factors affecting the acceptance of pre-pregnancy eugenic health examination for women of childbearing age and provide evidence for improving pre-pregnancy health care services.

A multi-stage stratified random sampling method was adopted to investigate the pre-pregnancy eugenic health examination of 1 995 women of childbearing age in Mianyang City, Sichuan Province through questionnaires. Based on the Andersen theoretical model, four logistic regression analysis models were established to explore the factors influencing the acceptance of pre-pregnancy eugenic health examination by women of childbearing age.

The rate of pre-pregnancy eugenic health examination was 61.1%, of which 53.1% were free and 46.9% were self-paid. The predisposing characteristics, enabling resource-financing, enabling resource-organization and perceived needs were incorporated into the regression model layer by layer. It was found that enabling resource-organization had the greatest impact. Model 4 had the strongest overall explanatory power. Logistic regression analysis results showed that women of childbearing age without insurance or only with commercial insurance (OR=0.526, 95% CI: 0.278-0.996) and those who purchased the urban-rural resident basic medical insurance (OR=0.757, 95% CI:0.597-0.959) had a lower rate of pre-pregnancy eugenic health examination compared to those who purchased urban employee basic medical insurance (P<0.05). From the organizational perspective, women of childbearing age who knew about the free pre-pregnancy eugenic health examination policy (OR=2.907, 95% CI: 2.267-3.728). From the perceived demand perspective, women who planned to get pregnant (OR=1.811,95% CI: 1.459-2.249) were more inclined to accept the pre-pregnancy eugenic health examination (P<0.05).

It is necessary to further promote the implementation of free pre-pregnancy health care service policy, strengthen health education based on primary medical and health institutions, and promote more women of childbearing age to take the initiative to accept pre-pregnancy eugenic health examination services.

To investigate the correlation and dose-response relationship of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with type 2 diabetes mellitus (T2DM) in the elderly aged over 65 years.

The participants were from the medical examination of the elderly aged 65 years and over in Wujin district, Changzhou city in 2022. The survey contents included questionnaire survey, physical examination and laboratory examination. Logistic regression and restricted cubic spline were used to analyze the correlation and dose-response relationship of NLR and PLR with T2DM.

A total of 112 073 individuals were included in this study, with an average age of 72.66±5.62 years. Among them, 53 557 (47.79%) were male, and 16 935 (15.11%) were T2DM patients. After adjusting for relevant confounding factors, compared with the Q1 group of PLR, the ORs (95% CI) for T2DM in the Q2, Q3, and Q4 groups were 0.93 (0.88-0.97), 0.83 (0.79-0.87), and 0.73 (0.70-0.77).respectively (P _fortrend <0.001). Compared with the Q1 group of NLR, the ORs (95% CI) for T2DM in the Q2, Q3, and Q4 groups were 1.12 (1.06-1.18), 1.19 (1.13-1.25), and 1.35 (1.28-1.42), respectively (P _fortrend <0.001). Subgroup analysis results showed that the established in this study demonstrates notable advantages, including simple operation, rapid reaction, high specificity, superior sensitivity, and low cost, and does not rely on specialized nucleic acid detection equipment, but only requires a thermostatic heating instrument to complete the detection. The method is suitable for the immediate detection of arthropod-borne viruses, offering a novel technical platform for arbovirus identification.correlation between PLR and NLR and T2DM remained statistically significant across subgroups stratified by sex, age, hypertension, BMI, and abdominal obesity (all P-values < 0.05). Hypertension status and gender had significant interactions with the association between PLR, NLR and T2DM (P _{forinteraction} < 0.05). The results of the restricted cubic spline showed that PLR had a negative nonlinear relationship with the prevalence of T2DM (P=0.008), and NLR had a positive nonlinear relationship with the prevalence of T2DM (P<0.001). The threshold effect inflection points of PLR and NLR on T2DM were 158.0 and 2.47 respectively (log-likelihood ratio test P<0.05).

The risk of T2DM increased with the increase of NLR and decreased with the increase of PLR. This study also found nonlinear dose-response relationships between NLR, PLR and T2DM.

To analyze the prevalence of diabetes and self-management behaviors among elderly Dai, Hani, and Bai in rural areas of Yunnan.

A multi-stage stratified random sampling approach was used to conduct a questionnaire survey and blood glucose measurement on 4 229 rural residents aged ≥60 years from the Dai, Hani, and Bai ethnic groups in Yunnan.

The age-standardized prevalence rate of diabetes among elderly individuals in the surveyed areas was 7.6%for the Dai ethnic group, 5.0% for the Hani ethnic group, and 16.0% for the Bai ethnic group. The differences in diabetes prevalence among the three ethnic groups were statistically significant (χ²=105.856, P<0.001), with the Bai group having the highest prevalence, followed by the Dai and then the Hani. The differences in prevalence among the three ethnic groups within each age group were all statistically significant (all P<0.01). Among diabetic patients, the rates of adhering to taking prescribed medications, self-monitoring blood glucose, and taking at least one measure to control blood glucose in the past two weeks were 94.7%, 42.1%, and 100.0% for the Dai ethnic group, 79.4%, 26.5%, and 94.1% for the Hani ethnic group, and 98.2%, 57.6%,and 98.8% for the Bai ethnic group, respectively. Across all three ethnic groups, dietary control was the most commonly adopted measure for managing blood glucose in the two weeks prior to the survey. The overall blood glucose control rate among the three ethnic groups was 47.7%. The blood glucose control rates among elderly diabetic patients were 50.9% for the Dai, 58.8% for the Hani, and 44.2% for the Bai ethnic groups, with no statistically significant differences observed among the groups (P>0.05).

Significant ethnic differences in diabetes prevalence and self-management behaviors are observed among elderly individuals from the Dai, Hani, and Bai ethnic groups in rural Yunnan. Targeted health interventions and management strategies should be developed to address ethnic backgrounds and health needs of these populations.

To explore the compliance of telemedicine services on third-party platforms since the release of the“Telemedicine Supervision Rules (Trial)” in 2022.

An anonymous standardized patient method was employed to assess the compliance of diagnostic behaviors on eight well-known, large-scale third-party internet healthcare platforms in China.Diagnostic scenarios were designed around five representative clinical cases. Based on the Telemedicine Supervision Rules (Trial),20 regulatory indicators were extracted across five key dimensions—clinical practice supervision, pharmaceutical services, prescription and medical record standards, identity verification, and quality and safety oversight.

The platforms generally deviated from policy requirements in areas such as online first diagnosis, medication prescribed before diagnosis and prescription authenticity, with average compliance rates of 29%, 25%, and 10%, respectively. Some platforms were suspected of using artificial intelligence to replace doctors in consultations. Compliance was better in areas such as physician qualification certification and real-name authentication, patient real-name authentication, termination of online medical services, and prohibiting patients from being directed to other medical providers, with only a few cases of violations. The causes of compliance issues included the policy’s failure to adapt to industry development, low government regulatory willingness, weak regulatory effectiveness, and the profit-driven behavior of platforms and healthcare providers.

Third-party platforms still face varying degrees of compliance issues in medical practices, pharmaceutical services, prescription regulation, and personnel identity management. It is recommended to strengthen government regulatory functions, enforce platform accountability, improve the dynamic adjustment mechanism of policies, and enhance social supervision and industry self-regulation.

To evaluate the applicability of the Job Content Questionnaire (JCQ-22) based on classical test theory (CTT) and item response theory, and to optimize and adjust it.

A survey of 917 occupational groups who had a physical examination at a hospital from September 1 to September 30, 2021 was conducted using JCQ-22, and the entries were comprehensively analyzed using the Rasch model, two-parameter logistic model (2PL), and grade-response model (GRM) in the IRT, combined with Cronbach’s α coefficient within CTT, and the factor analysis method.

In the IRT analysis, the difficulty coefficients of the entries ranged from -2.49 to 0.36, and the difficulty coefficients of “JOB4”, “JOB7”, “JOB10”,“JOB11” had a differentiation degree lower than 1.34, and the corresponding average information content was significantly lower than the other entries. In the CTT analysis, a total of 18 entries met the statistical criteria, therefore, combining the IRT and CTT, the JCQ-22 was optimized and adjusted, and the results showed that the adjusted scale JCQ-18 had 18 entries, which was more concise and had a more stable structure.

Most of the entries of JCQ-22 performed well, while some of the entries did not meet the acceptable standards and need further optimization.

To explore the mediating roles of self-care ability and self-rated health between physical inactivity and depressive symptoms among elderly individuals.

Data from 8 279 participants (≥60 years) in the 2020 CHARLS database were analyzed using correlation and regression to explore the relationship between physical inactivity, self-care ability, self-rated health and depressive symptoms. The chain mediating effect model was used to analyze the multiple mediating effects.

Depressive symptoms prevalence was 40.89% among people aged 60 and above. Physical inactivity (β=0.402, P<0.01), self-care ability (β=-0.186, P<0.001) and self-rated health (β=-1.724, P<0.001) directly predicted depressive symptoms. The simple mediation effects were 0.142 for self-care ability and 0.072 for self-rated health between physical inactivity and depressive symptoms, with a chain mediation effect of 0.056.

Self-care ability and self-rated health have a direct mediating effect and a chain mediating effect between physical inactivity and depressive symptoms in the elderly. Enhancing physical activity may improve body functional capacity, self-care ability and health, thereby reducing depressive symptoms risk.

To analyze the epidemiological characteristics of non-melanoma skin cancer (NMSC) in China from 2005 to 2018 and to predict future incidence trends, thereby providing a scientific basis for the prevention and control of NMSC.

Incidence data for NMSC from 2005 to 2018 were obtained from the Chinese Cancer Registry Annual Reports. Joinpoint regression was used to estimate the average annual percentage change (AAPC) and annual percentage change (APC) to reflect time trends. An age-period-cohort model based on the intrinsic estimator algorithm was employed to assess the effects of age, period, and birth cohort. A Bayesian age-period-cohort (BAPC) model using integrated nested Laplace approximation was applied to predict future trends.

From 2005 to 2018, the age-standardized incidence rate (ASIR) of NMSC in China was 1.33 per 100 000, showing an upward trend, with an AAPC of 3.7% (95% CI: 2.5%-4.9%). The ASIR was higher in males (1.46/100 000) than in females (1.21/100 000), although the increase was faster in females (AAPC = 8.8%). The incidence rate in urban areas (1.44/100 000) was higher than in rural areas (1.15/100 000). The risk of NMSC incidence increased with age. The cohort effect showed a downward trend in ASIR. Predictions suggested that the ASIR of NMSC in China will continue to rise, reaching 2.52/100 000 by 2030 (95%CI: 0.22/100 000-4.83/100 000), though future trends remain uncertain.

From 2005 to 2018, the ASIR of NMSC in China showed a rising trend, with significant differences across age, sex, and regions. It is recommended to strengthen targeted prevention and health education efforts in different areas to enhance public awareness of NMSC.

To explore the relationship between subjective cognitive decline and frailty in community-dwelling older adults with comorbidities, and analyze the mediating effects of self-perceptions of aging and cognitive reserve.

From June to October 2023, 505 community-dwelling older adults aged 65 and above in Xinxiang City with comorbidities were selected to conduct a questionnaire survey. Descriptive statistics, ANOVA and correlation analysis were performed on the data, and AMOS 27.0 was used to construct a chain mediation model.

Subjective cognitive decline had a positive impact on frailty (β=0.100, 95% CI: 0.006-0.191, P=0.040). Self-perceptions of aging and cognitive reserve played a mediating role between subjective cognitive decline and frailty (β=0.079, 95% CI: 0.042-0.123, P<0.001; β=0.029, 95% CI: 0.011-0.056, P<0.001), accounting for 36.12% and 13.37% of the total effect value, respectively. Moreover, self-perceptions of aging and cognitive reserve jointly played a chain-mediating role between subjective cognitive decline and frailty (β=0.010, 95% CI: 0.004-0.021, P<0.001), accounting for 4.77% of the total effect value.

The findings that self-perceptions of aging and cognitive reserve play independent mediating roles and a chain-mediating role between subjective cognitive decline and frailty suggest that attention should be paid to the subjective feelings of community-dwelling older adults with comorbidities. It is essential to cultivate a positive view of aging among the elderly and enhance their cognitive reserve levels. By doing so, the onset of frailty can be delayed, thus promoting healthy aging.