To explore the effects of social support and resilience on bullied secondary school students and non-suicidal self-injury, and analyze the association between social support and resilience, so as to provide reference for preventing school bullying. Method In March 2023, three middle schools in Jiangxi Province were used as site sites to investigate the current situation using self-made general situation questionnaire, Olweus Bully questionnaire, social support scale for adolescents，cognitive emotion regulation questionnaire (CERQ), Ottwa self-injury inventory questionnaire (OSI). To explore the role of social support and resilience in the chain mediation between bullying victimization and non-suicidal self-injury.

The report rate of bullying victimization was 18.56%, and the detection rate of non-suicidal self-injury was 34.4%. Bullying victimization and NSSI were negatively correlated with social support and resilience (r=-0.34 - -0.16, P<0.001), bullying victimization was positively correlated with NSSI (r=0.18, P<0.001), and social support was positively correlated with resilience (r=0.66, P<0.001). The results of mediating effect analysis showed that the simple mediating effect of social support between bullied and non-suicidal self-injury was 0.036 (95%CI:0.014-0.064), and the chain mediating effect of social support and resilience was 0.029 (95%CI: 0.011-0.056).

The bullying experience of secondary school students positively increases the risk of non-suicidal self-injury, and social support and resilience play chain mediating roles in this process. Improve the social support and resilience of secondary school students to reduce the non-suicidal self-injury behavior related to school bullying.

To analyze the mediating effect of depressive symptoms between unhealthy lifestyle and body mass index (BMI), and to provide a reference basis for the prevention of common diseases among adolescents.

In 2023, 88, 594 students were selected by random stratified, class-based cluster sampling method from 12 municipalities in Inner Mongolia (103 counties) for questionnaire survey, to describe the basic demographic characteristics of the students, to explore the correlation between unhealthy lifestyle, depressive symptoms and BMI, and to establish the mediation effect model by using the PROCESS macro program in SPSS 26.0.

The number of detections of unhealthy lifestyle was 85 866, with a detection rate of 96.92 percent; the number of detections of abnormal BMI was 32 078, with a detection rate of 36.21 per cent; and the number of detections of depressive symptoms was 19, 356, with a detection rate of 21.85 per cent. The results showed that the mediating effect value of depressive symptoms on unhealthy lifestyle and body mass index was 0.0770, 95%CI: 0.0513-0.1027, and the mediating effect accounted for 11.35% of the total effect, which indicated that unhealthy lifestyle could mediate the increase of BMI through depressive symptoms.

Adolescents can prevent abnormal body mass index by improving unhealthy lifestyles, and they can also improve the occurrence of depressive symptoms and thus maintain a normal body mass index.

Background Suicide has become a major public health issue of global concern. Suicidal ideation represents the initial psychological and one of the strongest predictorsactivities associated with suicidal behavior. Suicidal ideation is a dynamic state factor rather than a static trait factor, so it is necessary to study the development trajectory of suicidal ideation and its related factors.Objective To investigate the development trajectory and relatedfactors of suicide ideation college students.

From 2019 to 2021,1438 college students in a university in Guangdong Province were selected for three longitudinal tracking each October by using the method of convenient sampling. The Self-rating ideas of suicide scale (SIOSS) was used to measure the level of suicide ideation. Data analysis was mainly based on the Latent Growth Mixed Model(LGMM) to analyze the development trajectory of students’ suicide ideation. Multivariate Logistic Regression model was established to analyze the related factors to the variation of each potential category of suicidal ideation.

From 2019 to 2021, the total scores of college students’ suicidal ideation were 3.79±2.87, 3.71±2.90 and 3.32±2.87, showing a decreasing trend over time. The development tendencies of college students’suicide ideation have been classified into 3 categories: C1 group(worsening suicidal ideation group)(11.8%)，C2 group(persistent low suicidal ideation group)(79.6%), and C3 group (relieving suicidal ideation group) (8.6%). Compared with C1 group, college students who had an average (OR=2.52, 95% CI:1.31-4.86) or happy childhood (OR=3.95,95% CI:2.02-7.74), no history of suicide attempt (OR=9.03，95% CI:3.49-23.36), and were extroverted (OR=1.03, 95% CI:1.01-1.05) were more likely to enter C2 group. Students who were from cities (OR=0.54, 95% CI:0.31-0.93),got high neuroticism scores (OR=0.86, 95% CI:0.84-0.88) were less likely to enter the C2 group. College students with happy childhood life(OR=3.29, 95% CI:1.40-7.74)were more likely to enter the C3 group, but students from cities(OR=0.37, 95% CI:0.18-0.78)were less likely to enter the C3 group.

The development tendencies of college students’ suicide ideation can be classified into three categories: worsening suicidal ideation group,persistent low suicidal ideation group, and relieving suicidal ideation group. The developmental trajectory of suicidal ideation is related to birthplace, childhood life, suicide history, and personality traits.

To investigate the knowledge of monkeypox among men who have sex with men (MSM) in Central Jiangsu Province in 2023, and to provide evidence for the prevention and treatment of monkeypox in this population.

The monkeypox questionnaire designed by Jiangsu Provincial Center for Disease Control and Prevention was used to investigate HIV Voluntary Counseling & Testing (VCT) clinic and social organizations in central Jiangsu Province. Excel 2010 and SPSS19.0 software were used to organize and analyze the data. Also, univariate and multivariate Logistic regressions were used to analyze the factors affecting the awareness rate of monkeypox knowledge. χ² test was used to compare the difference of concern degree of monkeypox among people with different characteristics.

A total of 1 290 valid questionnaires were collected. The majority were aged from 26 to 50 years, accounting for 65.04% (839/1 290). The majority of the students were college students, bachelor students or above, accounting for 64.26% (829/1 290). The awareness rate of monkeypox was 26.12%, and the complete awareness rate was 15.27%. The results of multivariate Logistic regression analysis showed that the related factors with higher awareness rate of monkeypox included Taizhou (OR=6.710, 95%CI: 4.309-10.447), high school/technical school (OR=2.461, 95%CI: 1.270-4.769), college (OR=2.515, 95%CI: 1.311-4.825), bachelor’s degree or above (OR=2.253, 95%CI: 1.184-4.288), concerned about monkeypox epidemic and related situation (OR=1.684, 95%CI: 1.188-2.387) (all P < 0.05). The correct rates of monkeypox symptoms, preventive measures and transmission routes were 30.78%, 42.25% and 27.75%, respectively. 1 186 people (91.94%) paid attention to monkeypox epidemic and prevention knowledge from WeChat, Weibo and other network new media. MSM with different regions (χ²=65.348, P<0.001), age groups (χ²=19.422, P=0.001), educational levels (χ²=31.447, P<0.001), marital status (χ²=11.162, P=0.025), results of the latest HIV test (χ²=37.793, P<0.001), sexual orientations (χ²=39.441, P<0.001), whether they had sexual contact with the same sex in the last 6 months (χ²=29.329, P<0.001), and whether they had sexual contact with overseas personnel (χ²=29.199, P<0.001), paid different attention to monkeypox information, and the differences were statistically significant.

The awareness rate of MSM monkeypox knowledge in central Jiangsu Province is low, and the accuracy rate of monkeypox symptoms, transmission routes and prevention and control measures are low. Therefore, it is necessary to publicize monkeypox symptoms and transmission routes through new media such as WeChat, Weibo, Douyin and Baidu in the later stage.

To analyze the association of 11 anthropometric indicators (AIs) with gastric cancer and precancerous lesions in people aged 40-69 years in Yangzhong City.

Using the cluster sampling method, 10 698 residents aged 40-69 years who participated in upper gastrointestinal cancer screening in Yangzhong City from November 2017 to December 2022 were selected for questionnaire survey, physical examination, endoscopy and pathological diagnosis. Multivariate logistic regression was used to analyze the association between AIs [body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), body fat percentage (BF%), conicity index (CI), body adiposity estimator (BAE), a body shape index (ABSI), body adiposity index (BAI), body roundness index (BRI) and abdominal volumetric index (AVI)] and gastric cancer and precancerous lesions.

The prevalence of gastric cancer and precancerous lesions was 39.37% among 10 115 residents. The results of multivariate logistic regression showed that compared with those in quartile 1 (Q1), the Q3 and Q4 populations of BMI had an 11.1% (OR=0.889, 0.791-0.999) and 12.4% (OR=0.876, 0.779-0.984) lower risk of gastric cancer and precancerous lesions, respectively. The Q2, Q3 and Q4 populations of BF% had 14.2% (OR=0.858, 0.756-0.974), 17.4% (OR=0.826, 0.689-0.991) and 26.6% (OR=0.734, 0.603-0.893) lower risk of gastric cancer and precancerous lesions risk, respectively. The Q2 and Q4 populations of the BAE had reduced the risk of gastric cancer and precancerous lesions by 13.2% (OR=0.868, 0.766-0.983) and 21.3% (OR=0.787, 0.648-0.957). The risk of gastric cancer and precancerous lesions in BAI’s Q2 and Q3 populations was reduced by 13.7% (OR=0.863, 0.767-0.970) and 13.1% (OR=0.869, 0.769-0.983), respectively. Stratified analysis showed that BMI, BF%, BAE and BAI were associated with a reduced risk of non-cardia gastric cancer and precancerous lesions (all P<0.05). However, only the Q2 level of BAE was associated with a reduced risk of cardia gastric cancer and precancerous lesions compared to the Q1 (P<0.05).

Increased levels of BMI, BF%, BAE, and BAI among residents aged 40-69 years in Yangzhong City are associated with a reduced risk of gastric cancer and precancerous lesions. However, most of this association apply to non-cardia but not cardia.

To explore potential classifications and characteristics of mental health literacy among HIV-positive men who have sex with men.

From November 2023 to January 2024, 226 HIV-positive MSM in a tertiary hospital in Nanjing were selected by the convenience sampling method and were investigated by general information questionnaire and multicomponent mental health literacy scale. Latent class analysis and multivariate logistic regression analysis were used to explore the categorical characteristics and influencing factors of mental health literacy in this group.

The mental health literacy characteristics of HIV-positive MSM could be classified into low literacy group (22.1%), resource deficient group (38.1%), and high literacy group (39.8%). Multiple logistic regression analysis showed that patients aged 18-34 (OR=5.573, 95%CI=1.020-30.449) were more likely to be in the resource deficient group than the low literacy group, and those who had participated in learning mental health skills (OR=0.126, 95%CI=0.033-0.476) were more likely to be in the high literacy group. Compared with the high literacy group, patients with literacy level of junior high school or below (OR=15.992, 95%CI=2.036-125.591), high school or junior college (OR=2.805, 95%CI=1.098-7.166), length of time to diagnosis of HIV infection <1 year (OR=8.440, 95%CI=1.628-43.742), and with comorbidities (OR=6.619, 95%CI=1.077-40.663) were more likely to be in the low literacy group; and patients with a monthly per capita family income of <3000 yuan (OR=6.241, 95%CI=1.088-35.814) were more likely to be in the resource deprived group.

There are three potential categories of mental health literacy among HIV-positive MSM. In the future, targeted intervention strategies should be developed to improve the level of their mental health literacy and further improve their mental health according to this group’s different category characteristics and influencing factors.

To understand the willingness to use pre-exposure prophylaxis (PrEP) among MSM in Guiyang, explore related factors, so as to provide reference for promoting PrEP in Guiyang and Guizhou Province.

Two social organizations in Guiyang were recruited among MSM from gay bars, WeChat groups and other social venues and the Internet by convenient sampling method from April to June, 2022. Questionnaires were collected using the “Wen Juan Xing” platform, the contents of the survey included demographic information, behavioral characteristics, knowledge of PrEP, the willingness to use PrEP and so on. Univariate analysis of the willingness to use PrEP was used Chi-square test, logistics regression was carried out to analyze the multiple-factors related to the willingness to use PrEP. Taking the willingness to use PrEP as the dependent variable, univariate and multivariate logistics regression was carried out to analyze the factors related to the willingness to use PrEP.

608 valid questionnaires were collected. A total of 146 people (24.0%) knew about PrEP, 216 people (35.5%) had used PrEP before, and 525 people (86.3%) were willing to use PrEP if they had high-risk behaviors. The results of multivariate analysis showed that non-Guiyang resident (OR=3.09, 95%CI:1.42-6.73), living in Guiyang for 7-12 months (OR=5.12, 95%CI:2.25-11.65) and more than 1 year (OR=4.19, 95%CI:1.85-9.49), employed (OR=17.05, 95%CI:4.14-70.26), unemployed (OR=6.29, 95%CI:1.18-33.59), tested for HIV in the last 1 year (OR=3.77, 95%CI:1.70-8.38), those who had previously used PrEP (OR=15.85, 95%CI: 5.12-49.11) and aware of PrEP (OR=4.82, 95%CI: 1.88-12.38) were more likely to use PrEP.

The MSM population surveyed in Guiyang has a low awareness rate of PrEP, higher willingness to use PrEP, and relative factors, develop targeted measures to promote knowledge about PrEP according to relative factors, so as to improve the knowledge of PrEP, confidence and willingness to use PrEP. Promote the use of PrEP in the context of comprehensive AIDS prevention and control, such as the use of condoms, to reduce the risk of HIV infection.

To explore the non-immunization vaccines hesitancy and associated factors among parents of 0-18 years old children in Karamay.

Based on the theory of planned behavior (TPB), we used a stratified sampling method to select parents of 0-18 years old children in 12 schools of Karamay for a questionnaire-based survey．The structural equation model was used to determine relationships between variables.

Of 1 258 parents included in the analysis, the incidence of vaccine hesitancy among those was 38.95%. Logistic regression analysis showed that parents with younger children, higher educated, higher income, and longer local residence were less likely to be hesitant. The indicators of model fit are in line with the theoretical requirements. The model explains 56% of the variance of parental hesitancy to vaccinate. Attitudes (β_standard=-0.36, P<0.01), subjective norms (β_standard=-0.23, P<0.01), perceived behavioral control (β_standard=-0.21, P<0.01), and perceived risk (β_standard=-0.12, P<0.01) were associated with non-immunization vaccines hesitancy.

The TPB model can better explain parents’ hesitancy to receive non-immunization vaccines. To increase parental willingness about vaccinate, it is essential to strengthen parents’ trust in vaccine quality and knowledge of vaccines. Furthermore, utilizing physicians and social media for health education is crucial.

To explore the relationship between H-type hypertension and chronic kidney disease (CKD) and provide scientific basis for the prevention and treatment of chronic kidney disease.

From December 2021 to December 2022, 257 patients with CKD were randomly collected from the Department of Nephrology of Hunan Provincial People’s Hospital, and 257 patients were collected in the physical examination department as the control group. Data on general demographic characteristics, lifestyle habits, disease history, and clinical indicators were collected for all study subjects. The epidemic status and influencing factors of CKD, and the relationship between H-type hypertension and CKD were analyzed by univariate and multivariate analysis methods. An interaction model was constructed to analyze the interaction effect of homocysteine (Hcy) and hypertension on the onset of CKD. The effect of H-type hypertension and related influencing factors on CKD were explored by subgroup analysis.

The results of univariate analysis of general demographic characteristics and clinical indicators between CKD and control groups showed: age, ethnicity, educational level, per capita income, exercise status, sleep duration, BMI, history of H-type hypertension, triglycerides (TG), High-density lipoprotein cholesterol (HDL), albumin (ALB), glomerular filtration rate (GFR), blood urea nitrogen (BUN), uric acid (UA), Hcy, total bilirubin (TBIL), direct bilirubin (DBIL), C reactive protein (CRP) levels (P<0.05). Dichotomized Logistic regression analysis showed that the risk of CKD, adjusted for age, nationality, educational level, family income, exercise, sleep duration, BMI, TG, HDL, ALB, GFR, BUN, UA, TBIL, CRP was 2.333 times higher than in those without H-type hypertension(OR=2.333, 95%CI: 1.365-3.989, P=0.002). The interaction results between hyperhomocysteinemia (HHcy) and hypertension suggested that there was a positive additive interaction between HHcy and hypertension, with no multiplicative interaction. There was an interaction between H-type hypertension and age, educational level, average annual family income, and sleep duration on the onset of CKD (P<0.05).

H-type hypertension is a risk factor for CKD, and there is an additive interaction between the effects of HHcy and hypertension on CKD.

To construct a symptom network for patients with hypertensive cerebral hemorrhage in the acute phase, and to explore the core symptom clusters to provide reference for healthcare professionals to carry out individualized and precise symptom management.

From December 2022 to January 2024, 423 hypertensive cerebral hemorrhage patients hospitalized in the neurosurgery departments of three tertiary-level A hospitals in Hebei Province were conveniently selected for the study. General information questionnaire, Chinese version of Memory Symptom Assessment Scale, National Institutes of Health Stroke Scale, and Stroke Specific Quality of Life Scale were used to collect data. Symptom clusters were analyzed by exploratory factor analysis, symptom networks were constructed in R language to analyze the centrality indexes, and the symptom clusters that had the greatest impact on patients’ quality of life were clarified through stratified regression to determine the core symptom clusters.

The most common symptoms in patients with hypertensive cerebral hemorrhage were pain (83.5 %), worry (80.6%), nausea (75.7%), and the most severe symptom was pain (2.29±0.05), followed by nausea (1.93±0.06) and worry (1.72±0.06). Exploratory factor analysis identified five symptom clusters, namely, sickness symptom cluster, dysfunction symptom cluster, mental-emotional symptom cluster, respiratory symptom cluster, and gastrointestinal symptom cluster, with a cumulative variance contribution of 61.832%. The symptom with the highest expected impact value in the symptom network was pain (r_s=1.17). Stratified regression analyses showed that the cluster of sickness symptoms had the greatest impact on quality of life (β=-4.677，95%CI：-5.224 - -4.131，P<0.001), explaining 46.5% of the model.

The symptom cluster is the core symptom cluster in the acute phase of hypertensive cerebral hemorrhage patients, based on which healthcare professionals can take appropriate interventions to carry out symptom management and further improve the efficiency of symptom management.