Objective: To observe the therapeutic effect of of Wang's Sanhe (lychee, hawthorn and mandarin orange seed) Formula in the treatment of kidney deficiency and stasis type prostatic hyperplasia and its effect on patients' bladder function.Methods: 120 patients with kidney deficiency and stasis type prostatic hyperplasia admitted to the Affiliated Hospital of Shanxi University of Traditional Chinese Medicine from January 2022 to June 2024 were selected and divided into two groups by lottery method. The conventional group was treated with tamsulosin hydrochloride capsule, and the Wang's Sanhe Formula group was combined with Wang's Sanhe Formula on the basis of the conventional group. Bladder function, prostate volume, 24h urination frequency, Chinese medicine symptom scores and changes in the levels of prostate - specific antigen (PSA), monocyte chemokine 1 (MCP - 1) and interleukin-8 (IL- 8) were compared before and after the treatment in the two groups, and adverse reactions were counted in the two groups.Results: Comparison of bladder function before treatment between the conventional group and Wang's Sanhe Formula group showed no statistically significant difference (P > 0.05). Maximum urinary flow rate (Qmax), average urinary flow rate (Qave) and effective bladder capacity were all higher after treatment in the conventional group and Wang's Sanhe Formula group than before treatment, and the differences in voiding time, urinary flow time and time to peak were not statistically significant when compared with those before treatment (P > 0.05). Qmax, Qave, and effective bladder capacity were higher in Wang's Sanhe Formula group after treatment than in the conventional group, and there was no statistically significant difference in voiding time, urine flow time, and time to peak compared with the conventional group (P > 0.05). Comparison of prostate volume, 24h urination frequency and TCM symptom scores before treatment between the conventional group and Wang's Sanhe Formula group, the difference was not statistically significant (P > 0.05). The prostate volume, 24 h urination frequency, and TCM symptom scores decreased after treatment in the conventional group and Wang's Sanhe Formula group compared with those before treatment, and the Wang's Sanhe Formula group was lower than the conventional group after treatment (P < 0.05). Comparison of serum PSA, MCP - 1 and IL - 8 before treatment between the conventional group and Wang's Sanhe Formula group showed no statistically significant difference (P >0.05). Serum PSA, MCP - 1, and IL - 8 decreased after treatment in both the conventional group and Wang's Sanhe Formula group compared with the pre - treatment period, and were lower in the Wang's Sanhe Formula group than in the conventional group after treatment (P < 0.05). Comparing the incidence of adverse reactions between the two groups (11.67% in the conventional group and 8.33% in the Wang's Sanhe Formula group), the difference was not statistically significant (P > 0.05).Conclusion: Wang's Sanhe Formula applied to kidney deficiency and stasis type prostatic hyperplasia can reduce the size of prostate, improve bladder function, reduce serum PSA, MCP - 1, IL - 8 levels and alleviate symptoms.

Warming and Resolving method is one of the fundamental methods of clinical treatment of traditional Chinese medicine, and it can be seen in the Suwen - The Union of Heaven and Human Beings that the idea of the equilibrium between Yin and Yang can be clarified. The principle that yin and yang imbalance can lead to diseases in the human body. The treatment method of "Warming and Resolving" refers to using Warm Traditional Chinese Medicinal to correct the pathological state of yang deficiency in the body, and combining it with products that promote qi circulation, blood circulation, and blood stasis to resolve pathological results such as phlegm dampness, blood stasis, and pathological disorders caused by yang deficiency and inability to transport and transform. In clinical practice, early and mid stage liver cancer is commonly diagnosed with excess symptoms, while in the late stage, the syndrome gradually shifts from excess to deficiency, resulting in deficiency of positive qi and liver and kidney. On the basis of syndrome differentiation, modern doctors can achieve effective treatment of liver cancer by orally taking decoctions according to the theory of "Warming and Resolving". This article reviews the mechanism and research progress of some warm and warm drugs in the treatment of liver cancer from the perspective of modern pharmacology, providing reference for clinical medication.

This article interprets the pathological characteristics of coronary heart disease in the elderly from the perspective of the dysregulation of the "Qi - Blood - Vessel - Spirit" chain. It posits that deficiency is the fundamental basis of coronary heart disease in the elderly, with qi deficiency being the initiating factor. Prolonged qi deficiency leads to stagnation of deficient qi, which affects the blood, making qi stagnation and blood stasis the primary cause. When deficient qi stagnates in the vessels, vessel obstruction becomes the key pathological mechanism. When deficient qi stagnates and affects the spirit, mental restlessness becomes an independent risk factor. Based on this, the article summarizes the experience of the renowned traditional Chinese medicine practitioner Guo Shikui in treating coronary heart disease in the elderly by focusing on restoring the "Qi - Blood - Vessel - Spirit" chain. Specifically, for deficiency, tonifying qi is essential, promoting free flow through tonification; for blood stasis, activating circulation is appropriate, using free flow as tonification; for vessel obstruction, promoting free flow is crucial, warming and unblocking to relieve pain; for mental disturbance, harmonizing is the norm, resolving stagnation and calming the spirit. The aim is to provide a perspective and method for the treatment of coronary heart disease in the elderly with traditional Chinese medicine.

Objective: To investigate the clinical efficacy of the addition and subtraction of Duhuo Jisheng Decoction on the residual numbness of nerve root after intervertebral foramenoscopy.Methods: 80 patients with residual numbness of nerve roots after undergoing intervertebral foramen endoscopy treatment at Shangqiu Traditional Chinese Medicine Hospital were selected as the research subjects, and they were divided into 40 cases each in the conventional group(treated with methylcobalamin) and the traditional Chinese medicine group (treated with the modified Duhuo Jisheng Decoction on the basis of the conventional group) according to the method of the randomized numerical table generated by the computer for 4 consecutive weeks of treatment. The clinical effects of the two groups were compared. The numbness degree of lower limbs, lumbar function, nerve conduction velocity, evoked somatosensory potential, inflammatory factors and quality of life of the two groups were observed before and after treatment. Compare the adverse reactions and recurrence rates at 3 and 6 months between two groups.Results: After 4 weeks of treatment, the effective rate of the traditional Chinese medicine group was 92.50% (37/40), which was significantly higher than the 72.50%(29/40) effective rate of the conventional group, and the difference was statistically significant (P < 0.05). After treatment, the acupuncture test, visual analog scale (VAS) for numbness, nylon rope test score, Oswestry dysfunction index (ODI), lumbar spinal potential, cauda equina potential, cortical potential, and serum levels of tumor necrosis factor - α (TNF - α), high - sensitivity C - reactive protein (hs CRP), and interleukin - 1β (IL - 1β) in the traditional Chinese medicine group were significantly reduced compared to the conventional group (P < 0.05, P <0.01). The Japanese Orthopaedic Association's back pain score (JOA) and the motor conduction velocity of the tibial and common peroneal nerves were significantly increased compared to the conventional group (P < 0.01). After treatment, the role function, physical function, social function, and material life scores of the traditional Chinese medicine group were significantly higher than those of the conventional group (P < 0.01). The recurrence rate of the traditional Chinese medicine group was 2.50% (1/40) after a 6 - month follow - up, which was significantly lower than the conventional group's 15.00% (6/40), and the difference was statistically significant (P <0.05).Conclusion: The modified Duhuo Jisheng Decoction has a significant effect in treating residual numbness of nerve roots after intervertebral foramen endoscopy. It may improve nerve conduction velocity, alleviate numbness symptoms, improve lumbar spine function, and enhance quality of life by inhibiting inflammatory reactions, and has high safety.

The Jiexi acupoint (ST 41) belongs to the Stomach Meridian of Foot - Yangming and has a special anatomical location. Its clinical application reflects the holistic concept of "treating upper diseases from lower." This principle originates from the Huangdi Neijing, which states, "For diseases in the upper body, treat the lower body." This article explores Jiexi's therapeutic approach of treating upper diseases from below from five perspectives: tracing the origins of Jiexi, analyzing its nature, and clarifying its application, clarifying the use of Jiexi Point, enlightenment on the use of Jiexi Point. The Jiexi acupoint is also noted in the phrase "treat muscular atrophy by selecting points on the Yangming meridian," demonstrating its efficacy in treating ankle atrophy. As a key point on the stomach meridian, it helps to alleviate local edema and clear heat in the Stomach meridian. The stomach meridian of Foot - Yangming extends to the hairline and forehead, so needling the Jiexi acupoint can treat upper body conditions, such as headaches and brain disorders, by regulating them from below. In the five elements, Jiexi belongs to fire and shares an affinity with the eyes, heart, and pericardium. The upper portion of the Foot - Yangming meridian connects to the heart, while the major collateral vessel of the stomach, known as Xuli, is located at the point of the heart's pulsation. This connection lays the foundation for treating eye diseases, heart - related conditions, and mental disorders. As an acupoint on the meridian, Jiexi is also indicated for treating coughs, fevers, and chills. Additionally, the theory of "treating edema by targeting the meridian" suggests that Jiexi can be used to address both external coughs and stomach - related coughs accompanied by edema. Jiexi point has a wide range of clinical applications in combination with other points, and it is rich in special needling techniques. Jiexi and Yang Jiao points, both belonging to the fire element, can be used together to treat palpitations. A classic case is appended to verify their effectiveness.

Professor Xie Lin points out that the core pathogenesis of cervical spondylosis lies in the blockage of muscles, bones, and blood vessels, as well as the malnutrition of the muscles and bones. In clinical practice, the diagnosis and treatment should be based on the four diagnostic methods, to clarify the condition of deficiency or excess, and differentiate the symptoms. The treatment principle should focus on muscles and bones, with the main strategy being the elimination of excess and supplementation of deficiency, and the active use of horn medicine. In cases of wind, cold, phlegm, and blood stasis blocking the channels, it is necessary to expel the pathogenic factors, unblock the channels, and benefit the muscles and bones. When the internal organs are deficient in qi and blood, the treatment should aim to nourish the base, supplement deficiency, and nourish the muscles and bones. Additionally, associated symptoms should be considered, and treatments for muscle relaxation, liver wind elimination, and the relaxation of muscles and tendons should be used. Clinical practice has shown good results, as evidenced by the case examples provided.

This article is intended to introduce Professor Zhang Xikui's experience in diagnosing and treating gout. In the acute stage of gout, Baihu and Guizhi decoction is prescribed, supplemented with herbs that clear heat and eliminate dampness, cool blood and detoxify, and promote joint circulation. In the remission stage of gout, the formula for tonifying qi and unblocking collaterals is prescribed, supplemented with herbs that reduce phlegm and remove blood stasis, promote yang and cool the blood, resolve nodules and open collaterals, and invigorate the spleen and kidneys. According to the severity of pain and the course of the disease, the Shaoyao Gancao decoction is flexibly combined. Based on the severity of heat, dampness, phlegm, blood stasis, and deficiency, the treatment methods and medications are adjusted. It is also emphasized that the medication should be consistent and attention should be paid to lifestyle regulation.

Objective: To explore the clinical efficacy and mechanism of modified Ermiao Pills in improving refractory proteinuria of diabetic kidney disease(DKD) based on the ""Damp - Heat Damaging Kidney"" theory.Methods: A total of 126 patients with diabetic kidney disease were selected from the TCM department and nephrology department of Gulou Hospital affiliated to Nanjing University Medical School from January 2022 to January 2025. All patients were divided into the treatment group (Group A, n = 63) and the control group (Group B, n = 63) using a stratified randomization method with sealed envelopes. Group A received conventional basic treatment combined with modified Ermiao Pills, while Group B received only conventional basic treatment. Clinical assessments were conducted on enrollment day and at week 8 of treatment to evaluate TCM syndrome scores [including polydipsia, limb edema, sticky mouth, and epigastric distension], detect urinary protein profiles [24 - hour urine protein (24hUpro), urinary albumin (UAlb), urinary kidney injury molecule-1 (UKim - 1), urinary N - acetyl - β - D - glucosidase (UNAG)], analyze metabolomics parameters [palmitic acid, L - carnitine, phosphatidylcholine (PC), diacylglycerol (DG)], assess renal function[blood creatinine (Scr), blood urea nitrogen (BUN)], and evaluate safety indicators [red blood cells (RBC), alanine aminotransferase (ALT), albumin (Alb), glycated hemoglobin (HbA1c)]. The clinical efficacy of both groups was compared.Results: After treatment, compared with group B, the scores of polydipsia, limb edema, sticky mouth, epigastric and abdominal distension in group A, as well as the levels of 24hUpro, UAlb, UM - 1, UNAG, palmitic acid, Scr, BUN, were decreased (P < 0.05), while the levels of L - carnitine, PC and Dg were increased (P <0.05). Compared with group B, the total effective rate of group A increased (P <0.05).Conclusion: For the first time in a single - center randomized controlled trial, the combination of modified Ermiao pills and conventional treatment based on the ""damp - heat injuring kidney"" theory has been demonstrated to significantly improve refractory proteinuria in diabetic nephropathy, regulate metabolomic indicators, and protect renal function with high safety. Palmitic acid, L - carnitine, PC, and Dg may serve as potential therapeutic targets for modified Ermiao pills in treating refractory proteinuria of diabetic nephropathy.

Pediatric sinusitis is prevalent among children, which is mainly manifested by a large amount of turbid nasal discharge. Western medicine treats this disease mostly with oral antibiotics and nasal hormones, which have the disadvantages of uncertain efficacy and drug resistance. Traditional Chinese Medicine (TCM) treats this disease through oral and external use of Chinese herbal drugs, offering a relatively safe and low - side - effect treatment option. In this study, we believe that the onset of pediatric sinusitis is related to the external pathogens to the lungs closing to the surface and inside; the heat of the gallbladder leading to the congestion of the nose and orifices; spleen and stomach disorders causing to the imbalance of qi movement. The primary pathogenesis involves internal heat stagnation and obstruction of the nasal passages. The following methods should be used in treating this disease: to resolve the pathogens both external and internal, to dispel external evils and clear the heat in the lungs at the same time; pungent and bitter medicines should be used together, to relieve the heat in the gallbladder; to elevate the clearness and lower the turbidity, regulating the spleen and the stomach Qi. Tongqiao Shengjiang Powder is derived from "Shengjiang Powder", a classic formula for treating epidemics, and is modified by the addition of Magnolia biondii Pamp., ueraria lobata(Willd.) Ohwi, and Glycyrrhiza uralensis Fisch. This formula has excellent therapeutic effects for treating pediatric sinusitis. It has the efficacy of resolving external pathogens and clearing the heat in the lungs, elevating the clearness and lowering the turbidity, and improving nasal ventilation. Although its medicinal flavor is simple, the formula is comprehensive and covers several treatments. It can effectively treat pediatric nasosinusitis of various TCM syndrome types through addition or subtraction. In this paper, one case is attached for clinical reference.

Objective: To explore the clinical effect of Yiqi Huoxue Tongbi Decoction on hemiplegia after ischemic stroke with qi deficiency and blood stasis.Methods: A total of 80 patients with hemiplegia after ischemic stroke with qi deficiency and blood stasis syndrome in Hepatobiliary Hospital of Jiangyin Traditional Chinese Medicine from January 2022 to December 2024 were prospectively selected and divided into 2 groups with 40 cases each according to random number table method. The control group was treated with conventional western medicine, and the observation group was treated with Yiqi Huoxue Tongbi Decoction combined with western medicine. Symptom improvement, curative effect, hemorheology, motor function, neurological function and safety were compared between the two groups. Results After treatment, TCM syndrome score, HCT, FIB, CRP, CysC and BNP levels were decreased in both groups, and the decrease was significant in the observation group (P < 0.05). After treatment, FMA scores and BBS scores in two groups were increased, and the increases in observation group were significant (P < 0.05). The curative effect of observation group was higher than that of control group (P < 0.05).Conclusion: The treatment of Yiqi Huoxue Tongbi Decoction for hemiplegia patients after ischemic stroke with qi deficiency and blood stasis syndrome can promote blood circulation, improve nerve function, and promote the recovery of motor function, so as to effectively improve the curative effect.