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To study the effects of Modified Yulin Zhu combined with warm acupuncture on endometrial receptivity and serum leukemia inhibitory factor (LIF) vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9) levels in patients with thin endometrium of renal deficiency and blood stasis type.
84 patients with thin endometrium (renal deficiency and blood stasis type) admitted to Taizhou Hospital of Traditional Chinese Medicine from January 2023 to September 2024 were selected, the grouping method was random number table method, the patients were divided into control group (treated with estradiol tablets/estradiol dydrogesterone tablets composite packaging, 42 cases) and observation group (treated with Modified Yulin Zhu and warm acupuncture on the basis of control group, 42 cases), the clinical efficacy, traditional Chinese medicine syndrome score, menstrual blood volume score, endometrial receptivity, serum LIF, VEGF, MMP-9 and incidence of adverse reactions were compared between two groups.
The total clinical effective rate of the observation group was higher than that of control group (P <0.05). Traditional Chinese medicine syndrome score in observation group were lower than those in control group 3 months after treatment, the endometrial thickness was greater than that in control group, and menstrual blood volume score, serum LIF, MMP-9 and VEGF were higher than those in control group (P <0.01). There was no difference in the incidence of adverse reactions between the observation group and the control group (P > 0.05).
Modified Yulin Zhu combine with warm acupuncture treatment, which can improve the clinical symptoms of patients with thin endometrium of renal deficiency and blood stasis type, and regulate endometrial receptivity, which may be relate to the improvement of serum LIF, VEGF and MMP-9 levels.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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