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  • Acta Chinese Medicine and Pharmacology. 2026, 54(1): 97-100.
    Objective: To explore the clinical effect of Yiqi Huoxue Tongbi Decoction on hemiplegia after ischemic stroke with qi deficiency and blood stasis.Methods: A total of 80 patients with hemiplegia after ischemic stroke with qi deficiency and blood stasis syndrome in Hepatobiliary Hospital of Jiangyin Traditional Chinese Medicine from January 2022 to December 2024 were prospectively selected and divided into 2 groups with 40 cases each according to random number table method. The control group was treated with conventional western medicine, and the observation group was treated with Yiqi Huoxue Tongbi Decoction combined with western medicine. Symptom improvement, curative effect, hemorheology, motor function, neurological function and safety were compared between the two groups. Results After treatment, TCM syndrome score, HCT, FIB, CRP, CysC and BNP levels were decreased in both groups, and the decrease was significant in the observation group (P < 0.05). After treatment, FMA scores and BBS scores in two groups were increased, and the increases in observation group were significant (P < 0.05). The curative effect of observation group was higher than that of control group (P < 0.05).Conclusion: The treatment of Yiqi Huoxue Tongbi Decoction for hemiplegia patients after ischemic stroke with qi deficiency and blood stasis syndrome can promote blood circulation, improve nerve function, and promote the recovery of motor function, so as to effectively improve the curative effect.
  • Acta Chinese Medicine and Pharmacology. 2026, 54(1): 101-105.
    Objective: To observe the therapeutic effect of of Wang's Sanhe (lychee, hawthorn and mandarin orange seed) Formula in the treatment of kidney deficiency and stasis type prostatic hyperplasia and its effect on patients' bladder function.Methods: 120 patients with kidney deficiency and stasis type prostatic hyperplasia admitted to the Affiliated Hospital of Shanxi University of Traditional Chinese Medicine from January 2022 to June 2024 were selected and divided into two groups by lottery method. The conventional group was treated with tamsulosin hydrochloride capsule, and the Wang's Sanhe Formula group was combined with Wang's Sanhe Formula on the basis of the conventional group. Bladder function, prostate volume, 24h urination frequency, Chinese medicine symptom scores and changes in the levels of prostate - specific antigen (PSA), monocyte chemokine 1 (MCP - 1) and interleukin-8 (IL- 8) were compared before and after the treatment in the two groups, and adverse reactions were counted in the two groups.Results: Comparison of bladder function before treatment between the conventional group and Wang's Sanhe Formula group showed no statistically significant difference (P > 0.05). Maximum urinary flow rate (Qmax), average urinary flow rate (Qave) and effective bladder capacity were all higher after treatment in the conventional group and Wang's Sanhe Formula group than before treatment, and the differences in voiding time, urinary flow time and time to peak were not statistically significant when compared with those before treatment (P > 0.05). Qmax, Qave, and effective bladder capacity were higher in Wang's Sanhe Formula group after treatment than in the conventional group, and there was no statistically significant difference in voiding time, urine flow time, and time to peak compared with the conventional group (P > 0.05). Comparison of prostate volume, 24h urination frequency and TCM symptom scores before treatment between the conventional group and Wang's Sanhe Formula group, the difference was not statistically significant (P > 0.05). The prostate volume, 24 h urination frequency, and TCM symptom scores decreased after treatment in the conventional group and Wang's Sanhe Formula group compared with those before treatment, and the Wang's Sanhe Formula group was lower than the conventional group after treatment (P < 0.05). Comparison of serum PSA, MCP - 1 and IL - 8 before treatment between the conventional group and Wang's Sanhe Formula group showed no statistically significant difference (P >0.05). Serum PSA, MCP - 1, and IL - 8 decreased after treatment in both the conventional group and Wang's Sanhe Formula group compared with the pre - treatment period, and were lower in the Wang's Sanhe Formula group than in the conventional group after treatment (P < 0.05). Comparing the incidence of adverse reactions between the two groups (11.67% in the conventional group and 8.33% in the Wang's Sanhe Formula group), the difference was not statistically significant (P > 0.05).Conclusion: Wang's Sanhe Formula applied to kidney deficiency and stasis type prostatic hyperplasia can reduce the size of prostate, improve bladder function, reduce serum PSA, MCP - 1, IL - 8 levels and alleviate symptoms.
  • Acta Chinese Medicine and Pharmacology. 2026, 54(1): 106-111.
    Objective: To investigate the clinical efficacy of the addition and subtraction of Duhuo Jisheng Decoction on the residual numbness of nerve root after intervertebral foramenoscopy.Methods: 80 patients with residual numbness of nerve roots after undergoing intervertebral foramen endoscopy treatment at Shangqiu Traditional Chinese Medicine Hospital were selected as the research subjects, and they were divided into 40 cases each in the conventional group(treated with methylcobalamin) and the traditional Chinese medicine group (treated with the modified Duhuo Jisheng Decoction on the basis of the conventional group) according to the method of the randomized numerical table generated by the computer for 4 consecutive weeks of treatment. The clinical effects of the two groups were compared. The numbness degree of lower limbs, lumbar function, nerve conduction velocity, evoked somatosensory potential, inflammatory factors and quality of life of the two groups were observed before and after treatment. Compare the adverse reactions and recurrence rates at 3 and 6 months between two groups.Results: After 4 weeks of treatment, the effective rate of the traditional Chinese medicine group was 92.50% (37/40), which was significantly higher than the 72.50%(29/40) effective rate of the conventional group, and the difference was statistically significant (P < 0.05). After treatment, the acupuncture test, visual analog scale (VAS) for numbness, nylon rope test score, Oswestry dysfunction index (ODI), lumbar spinal potential, cauda equina potential, cortical potential, and serum levels of tumor necrosis factor - α (TNF - α), high - sensitivity C - reactive protein (hs CRP), and interleukin - 1β (IL - 1β) in the traditional Chinese medicine group were significantly reduced compared to the conventional group (P < 0.05, P <0.01). The Japanese Orthopaedic Association's back pain score (JOA) and the motor conduction velocity of the tibial and common peroneal nerves were significantly increased compared to the conventional group (P < 0.01). After treatment, the role function, physical function, social function, and material life scores of the traditional Chinese medicine group were significantly higher than those of the conventional group (P < 0.01). The recurrence rate of the traditional Chinese medicine group was 2.50% (1/40) after a 6 - month follow - up, which was significantly lower than the conventional group's 15.00% (6/40), and the difference was statistically significant (P <0.05).Conclusion: The modified Duhuo Jisheng Decoction has a significant effect in treating residual numbness of nerve roots after intervertebral foramen endoscopy. It may improve nerve conduction velocity, alleviate numbness symptoms, improve lumbar spine function, and enhance quality of life by inhibiting inflammatory reactions, and has high safety.
  • CHEN Yanni, WANG Jiaqin, WU Min
    Acta Chinese Medicine and Pharmacology. 2026, 54(1): 112-115.
    Objective: To observe and analyze the clinical efficacy of Professor Wu Min's anti - allergy Formula from from Shanghai - style Xu's Pediatrics in treating pediatric allergic rhinitis.Methods: A total of 136 pediatric patients with allergic rhinitis treated at Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine and Youyi Community Health Service Center from December 2020 to December 2023 were collected and randomly divided into a treatment group (68 cases, loratadine tablets + anti - allergy Formula) and a control group (68 cases, loratadine tablets). Serum immune indicators and inflammatory factor levels in nasal secretions were measured and compared between the two groups. Symptom improvement and clinical efficacy were evaluated, and adverse reactions were recorded.Results: After treatment, the total serum immunoglobulin (Ig) E and the ratio of helper T cells (Th) 17/regulatory T cells (Treg) in the treatment group were significantly lower than those in the control group (P < 0.05). The interleukin (IL) - 4 level in nasal secretions of the treatment group was significantly lower than that of the control group (P <0.05), while the IL - 10 level was significantly higher (P < 0.05). After treatment, the scores for nasal congestion, nasal itching, runny nose, and sneezing in the treatment group were significantly lower than those in the control group (P <0.05). The total effective rate in the treatment group was significantly higher than that in the control group (P < 0.01). There was no significant difference in the incidence of adverse reactions such as gastrointestinal symptoms and skin reactions between the treatment group and the control group (P >0.05).Conclusion: Professor Wu Min's anti - allergy Formula is highly effective in treating pediatric allergic rhinitis, regulating immune function, reducing inflammatory responses, alleviating symptoms such as nasal congestion and itching, and demonstrating high safety.
  • Acta Chinese Medicine and Pharmacology. 2026, 54(1): 116-121.
    Warming and Resolving method is one of the fundamental methods of clinical treatment of traditional Chinese medicine, and it can be seen in the Suwen - The Union of Heaven and Human Beings that the idea of the equilibrium between Yin and Yang can be clarified. The principle that yin and yang imbalance can lead to diseases in the human body. The treatment method of "Warming and Resolving" refers to using Warm Traditional Chinese Medicinal to correct the pathological state of yang deficiency in the body, and combining it with products that promote qi circulation, blood circulation, and blood stasis to resolve pathological results such as phlegm dampness, blood stasis, and pathological disorders caused by yang deficiency and inability to transport and transform. In clinical practice, early and mid stage liver cancer is commonly diagnosed with excess symptoms, while in the late stage, the syndrome gradually shifts from excess to deficiency, resulting in deficiency of positive qi and liver and kidney. On the basis of syndrome differentiation, modern doctors can achieve effective treatment of liver cancer by orally taking decoctions according to the theory of "Warming and Resolving". This article reviews the mechanism and research progress of some warm and warm drugs in the treatment of liver cancer from the perspective of modern pharmacology, providing reference for clinical medication.
  • Acta Chinese Medicine and Pharmacology. 2026, 54(1): 122-128.
    Chronic musculoskeletal pain (CMP) is the most common type of chronic pain and includes cervical spondylosis, frozen shoulder, knee osteoarthritis, myofascial pain syndrome, rheumatoid arthritis, and fibromyalgia. At present, the clinical treatment of CMP is mainly based on drug therapy, but there are many adverse reactions in the treatment of Western medicine and there are differences in drug efficacy between different indications. Acupotomy therapy combines the advantages of traditional Chinese medicine acupuncture and Western medical surgical therapy, and is widely used in the treatment of CMP in clinical practice. Acupotomy therapy can improve the structure and function of the musculoskeletal system, affect the conduction of pain, and reduce inflammation through local release, thereby relieving pain and improving limb function. This article summarizes the application and progress of the underlying mechanisms of Acupotomy therapy in the field of CMP, aiming to provide a reference for the prevention and treatment of CMP and the clinical application of Acupotomy therapy.