Objective: To investigate the clinical efficacy of the addition and subtraction of Duhuo Jisheng Decoction on the residual numbness of nerve root after intervertebral foramenoscopy.Methods: 80 patients with residual numbness of nerve roots after undergoing intervertebral foramen endoscopy treatment at Shangqiu Traditional Chinese Medicine Hospital were selected as the research subjects, and they were divided into 40 cases each in the conventional group(treated with methylcobalamin) and the traditional Chinese medicine group (treated with the modified Duhuo Jisheng Decoction on the basis of the conventional group) according to the method of the randomized numerical table generated by the computer for 4 consecutive weeks of treatment. The clinical effects of the two groups were compared. The numbness degree of lower limbs, lumbar function, nerve conduction velocity, evoked somatosensory potential, inflammatory factors and quality of life of the two groups were observed before and after treatment. Compare the adverse reactions and recurrence rates at 3 and 6 months between two groups.Results: After 4 weeks of treatment, the effective rate of the traditional Chinese medicine group was 92.50% (37/40), which was significantly higher than the 72.50%(29/40) effective rate of the conventional group, and the difference was statistically significant (P < 0.05). After treatment, the acupuncture test, visual analog scale (VAS) for numbness, nylon rope test score, Oswestry dysfunction index (ODI), lumbar spinal potential, cauda equina potential, cortical potential, and serum levels of tumor necrosis factor - α (TNF - α), high - sensitivity C - reactive protein (hs CRP), and interleukin - 1β (IL - 1β) in the traditional Chinese medicine group were significantly reduced compared to the conventional group (P < 0.05, P <0.01). The Japanese Orthopaedic Association's back pain score (JOA) and the motor conduction velocity of the tibial and common peroneal nerves were significantly increased compared to the conventional group (P < 0.01). After treatment, the role function, physical function, social function, and material life scores of the traditional Chinese medicine group were significantly higher than those of the conventional group (P < 0.01). The recurrence rate of the traditional Chinese medicine group was 2.50% (1/40) after a 6 - month follow - up, which was significantly lower than the conventional group's 15.00% (6/40), and the difference was statistically significant (P <0.05).Conclusion: The modified Duhuo Jisheng Decoction has a significant effect in treating residual numbness of nerve roots after intervertebral foramen endoscopy. It may improve nerve conduction velocity, alleviate numbness symptoms, improve lumbar spine function, and enhance quality of life by inhibiting inflammatory reactions, and has high safety.

Modified Duhuo Jisheng Decoction  /  Percutaneous endoscopic lumbar discectomy  /  Residual radicular Numbness