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  • Xing-meng NIU, Si-fang NIU, Hui-ming ZHANG, Shu-zhang HU, Yu SUN, Yang-zi-ye GUO, Yan QIN, Lin-tao XUE, Si-yu LIU, Fu-qin MU, Yi ZHENG, Yan LIU
    Modern Preventive Medicine. 2025, 52(2): 274-279.
    Objective

    The Perth Alexithymia Questionnaire (PAQ) was translated into a Chinese version of the questionnaire and tested for reliability and validity in adolescents.

    Methods

    The Chinese version of the PAQ scale was formed according to the procedures of forward translation, back translation, cultural adaptation and pre-survey. During February and April 2024, 7 975 adolescents from Shandong Province, Anhui Province, and Hunan Province were selected to test the reliability of the Chinese version of the PAQ. The item analysis was performed using the coefficient of determination and correlation coefficient methods, and the reliability and validity were assessed using confirmatory factor analysis, criterion-related validity, internal consistency reliability, and test-retest reliability. The Toronto Alexithymia Scale, the Patient Health Questionnaire and the Generalized Anxiety Disorder Scale were used as validity scales, and 1 083 adolescents were retested 4 weeks later to determine the reliability of the retest.

    Results

    The results of the confirmatory factor analysis showed that the Chinese version of the PAQ scale was a 5-factor model (GFI=0.921, NFI=0.938, CFI=0.940, TLI=0.931, RMSEA=0.060). The Cronbach α coefficient for the Chinese version of the PAQ total scale was 0.953. The Cronbach α coefficients for the five subscales of Negative-Difficulty Identifying Feelings, Positive-Difficulty Identifying Feelings, Negative-Difficulty Describing Feelings, Positive-Difficulty Describing Feelings, and General-Externally Orientated Thinking were 0.821, 0.852, 0.807, 0.834 and 0.859, respectively. The retest reliability of the Chinese version of the PAQ scale was 0.762. The retest reliabilities for the five subscales of Negative-Difficulty Identifying Feelings, Positive-Difficulty Identifying Feelings, Negative-Difficulty Describing Feelings, Positive-Difficulty Describing Feelings, and General-Externally Orientated Thinking were 0.717, 0.676, 0.716, 0.709 and 0.692, respectively. The total score of the Chinese version of the PAQ scale was positively correlated with the total score of the Toronto Alexithymia Scale, depressive symptoms, and anxiety symptoms (r=0.782, 0.378, 0.369, P<0.01).

    Conclusion

    The Chinese version of the PAQ scale showed excellent psychometric properties on all measures in the adolescent population and can be used as an important tool for assessing adolescents’ alexithymia.

  • Ying-qi LUO, Xia ZENG, Ying-shi DAI, Yan-hui LIU, Liu-quan JIANG, Hong-xia ZHAO, Gai-sheng LIU, Qing-song CHEN
    Modern Preventive Medicine. 2025, 52(2): 232-239.
    Objective

    To explore the relationship between occupational physical activity and dyslipidemia among coal mine employees, providing reference for improving the prevention and control of dyslipidemia among coal mine employees and formulating health strategies.

    Methods

    This study was conducted in 2023 at Xishan coal electricity corporation occupational disease prevention and control institute. It was a cross-sectional study, with a total of 9 864 coal mine employees included in the analysis. We collected physical activity data using the International Physical Activity Questionnaire, and diagnosed dyslipidemia using the "Chinese Guidelines for the Prevention and Treatment of Adult Blood Lipid Disorders". We analyzed the relationship between occupational physical activity and dyslipidemia among coal mine employees using a multiple factor logistic regression model.

    Results

    The proportion of low, medium, and high intensity occupational physical activities among coal mine employees were 38.42%, 35.75%, and 25.83%, respectively. There were intergroup differences (P<0.05) in the incidence of high TG and dyslipidemia among occupational physical activities of different intensities, but this difference was not observed in the incidence of high TC, low HDL, and high LDL (P>0.05). After adjusting for factors such as gender, age, and leisure time physical activity, the incidence of dyslipidemia was lower among coal miners engaged in moderate to high-intensity occupational physical activity compared to those engaged in low-intensity physical activity (OR=0.84, 95%CI:0.76-0.94; OR=0.77, 95%CI:0.69-0.87); The incidence of low HDL was also lower (OR=0.85, 95%CI:0.77-0.95; OR=0.83, 95%CI:0.73-0.93).

    Conclusion

    There is a negative correlation between occupational physical activity and dyslipidemia among coal mine employees. For coal mine workers engaged in low-intensity occupational physical activities, it is recommended to intervene in other modifiable behavioral risk factors related to dyslipidemia to maintain healthy blood lipid levels.

  • Yi-ran ZHOU, Yin-xia SU, Feng YIN, Guligiayina·Aiken, Yao-qin LU
    Modern Preventive Medicine. 2025, 52(2): 211-219.
    Objective

    To explore the correlation between complex multimorbidity and their influencing factors and to reveal the interactions between diseases and factors using network inference methods to identify high-risk populations.

    Methods

    Based on longitudinal data from 2016 to 2022 in the Urumqi public health surveillance database and electronic medical record information database, this study collected information on the occurrence of complex multimorbidity and related variables. The structure of the Bayesian network was learned using the maximum-minimum hill-climbing algorithm combined with prior knowledge, and parameter learning was conducted using Bayesian estimation. Directed acyclic graphs were employed to identify confounding factors and guide the construction of regression models.

    Results

    A total of 6 938 participants were included in the study, of which 12.96% (899/ 6 938) developed complex multimorbidity over the seven-year period. After screening influencing factors, six predictors were selected for model construction, resulting in a model with 7 nodes and 10 directed edges. The results indicated that age, gender, source, and BMI weredirectly related to the occurrence of complex multimorbidity, all serving as parent nodes in the model. The results of logistic regression based on DAG guidelines showed that the risk of complex multimorbidity would increase by 8.70% [OR=1.087 (95%CI:1.077-1.098)] for each year of age increase in patients with chronic diseases; the OR of complex multimorbidity for rural residents compared to urban residents=0.274 (95%CI: 0.237-0.317); the OR of complex multimorbidity for obese people compared with thenormal weight people=1.019 (95%CI: 1.008-1.504).

    Conclusion

    Bayesian networks effectively identify the relationships between complex multimorbidity and influencing factors, as well as the interactions among these factors, thus enabling inference about the risk of complex multimorbidity occurrence. Prevention and control of complex multimorbidity requires attention to aging, urban environments, and obesity management.

  • Shi-wen LI, Yang LIU, Ji-bin LI
    Modern Preventive Medicine. 2025, 52(2): 253-259.
    Objective

    To investigate the effect of tea intake on cognitive function in the elderly and the mediating role of relationship of impaired activities of daily living (ADLs) and depressive states.

    Methods

    The data for this study came from the 2018 China Longitudinal Health and Longevity Survey (CLHLS), which included a total of 8,818 valid samples. The logistic regression was used to analyze the effects of frequency and type of tea drinking on cognitive function in the elderly, and the possible mechanism of this effect was further explored using a chain multiple mediation model.

    Results

    The elderly who regularly consumed tea were less likely to develop cognitive impairment (OR=0.80, 95% CI: 0.68-0.95), in which only green tea consumption was observed to be a protective factor for the development of cognitive impairment (OR=0.81, 95%CI: 0.65-1.00), and no significant evidence was found for other types of tea. Impaired activities of daily living and depressive state mediated the effect of regular tea consumption on cognitive functioning, with beta values and 95%CIs of -0.005 (-0.008--0.001) and -0.005(-0.007--0.003), while the continuous mediating effects of the two mediating variables, although significant, had β-values that were too small and effects that accounted for too little to be of practical significance.

    Conclusion

    Regular tea consumption is associated with a reduced risk of developing cognitive impairment in the elderly, especially among those who consume green tea. Impairment in activities of daily living and depression levels almost exclusively mediated the association between tea consumption and cognitive function.

  • Meng-ling WEI, Hui-yu HE, Juan WANG, Jiao ZHONG, Lei HUANG, Yang ZHANG, Ya-jia LAN
    Modern Preventive Medicine. 2025, 52(2): 342-348.
    Objective

    To investigate the association between biological aging and cognitive function in middle-aged and elderly Chinese.

    Methods

    The subjects were health check-up personnel over 45 years old from a top three hospital. The general demographic characteristics, covariates and cognitive function status were collected by questionnaire and Montreal cognitive assessment (MoCA). Multivariate linear regression and logistic regression were used to analyze biological aging index (BAI) and biological aging type (BAT) association with MoCA score and risk of mild cognitive impairment (MCI). Subgroup analysis was conducted by the middle-aged group (45-64 years old) and the elderly group (65 years old and above) to explore whether the correlation between biological aging and cognitive function was different in different age groups.

    Results

    A total of 407 participants were included in this study. The average MoCA score was 23.30±4.30, and the detection rate of MCI was 41.5%. BAI was negatively correlated with MoCA score, and the regression coefficient after adjusting for covariates was -0.135 (95%CI: -0.229--0.042). Compared with those with delayed aging, subjects with premature aging had lower cognitive function scores (β=-0.882,95%CI:-1.566--0.198) and a higher risk of MCI (OR=1.736,95%CI:1.072-2.833). Subgroup analysis found that the association was still present in the middle-aged group, but not in the elderly group.

    Conclusion

    There is a negative correlation between biological aging and cognitive function in middle-aged and elderly people, and the cognitive function of subjects with premature aging is worse. This effect is more significant in middle-aged group, suggesting that individuals with premature aging should be identified in middle age or even earlier and that intervention measures should be taken to prevent or delay the occurrence of dementia.

  • Xiao-rong NI, Li-yan ZHU, Ying XIONG, Li CHEN, Dan LI, Jia-wei LI
    Modern Preventive Medicine. 2025, 52(2): 280-285.
    Objective

    To explore the current status of coupled coordination of medical resource supply and service utilization in township health hospitals in Sichuan Province, and to provide reference for optimizing medical resource allocation.

    Methods

    The data concerning the allocation of health resources and the utilization of services in township health centers of various cities (prefectures) in Sichuan Province from 2017 to 2021 were selected. The comprehensive evaluation index was utilized to comprehensively assess the allocation of health resources and service utilization, and the coupling coordination degree model was employed to analyze the relationship between the two systems.

    Results

    The comprehensive evaluation index of medical resource supply and service utilization in township health centers in Sichuan Province improved from 0.27 and 0.45 in 2017 to 0.30 and 0.52 in 2021, respectively, and more than 90% of the areas were subject to lagging medical resource supply; the type of coupling coordination ranged from reluctant coupling coordination to primary coupling coordination; reluctant coordination was the main type; and the LISA chart showed Aba as the "high - high" aggregation point, Luzhouwas low - low aggregation point.

    Conclusion

    The level of resource supply and service utilization and coupled coordinated development of township health centers in Sichuan Province has been increasing, and the level of health resource supply and service utilization has not been synergistically developed, and most of them are subject to the lagging supply of health resources, and there is a localized aggregation effect of the degree of coupled coordination in space.

  • Hong-xia GAO, Jing CHEN, Xiao-hong ZHANG, Li-ming HOU, Li-jie WANG, Ya-qing MENG, Wen GAO, Ya-xin HUANG
    Modern Preventive Medicine. 2025, 52(2): 267-273.
    Objective

    To analyze the influencing factors on the occurrence of anxiety and depression among secondary school students in Shanxi Province in 2023 based on the random forest algorithm and to construct a prediction model to provide a scientific basis for preventing and controlling the occurrence of negative emotions such as anxiety and depression among secondary school students.

    Methods

    In September 2023, 104 826 secondary school students in 11 cities of Shanxi Province were selected by stratified random whole-cluster sampling method for questionnaire survey, and the Generalized Anxiety Scale (GAD-7) and the Center for Streamlined Depression Scale (CES-D) were used to investigate anxiety and depression. Epidata was used for database establishment, chi-square test was used for between-group comparisons, logistic regression was used for influencing factor analysis, and Python 3.7 was used to establish a random forest prediction model and rank the importance of each variable.

    Results

    The detection rates of anxiety and depression among secondary school students in Shanxi Province in 2023 were 33.26% and 23.72%, respectively, and were higher for girls than for boys, and higher for students in general and vocational high schools than for junior high school students. The results of multifactorial regression analysis showed that female students(OR: 1.846、1.655,95% CI: 1.794-1.901、1.602-1.710), high school(OR: 2.019、1.670,95% CI: 1.956-2.083、1.612-1.731), vocational high school(OR: 1.167、1.356,95% CI: 1.085-1.254、1.254-1.466), non-conventional family(OR: 1.105、1.248,95% CI: 1.072-1.140、1.206-1.292), living in school(OR: 1.102、1.117,95% CI: 1.070-1.136、1.080-1.155), eating fried food ≥1 time/day(OR: 1.296、1.375,95% CI: 1.227-1.369、1.297-1.457), being seriously injured(OR: 1.636、1.688,95% CI: 1.524-1.755、1.569-1.816), being bullied in school(OR: 2.315、3.411,95% CI: 2.150-2.492、3.165-3.677), being scolded by parents(OR: 2.881、3.191,95% CI: 2.766-3.001、3.059-3.328), smoking(OR: 1.344、1.435,95% CI: 1.266-1.427、1.349-1.527), drinking alcohol(OR: 2.062、2.113,95% CI: 1.978-2.151、2.022-2.208), and Internet addiction(OR: 3.635、3.976,95% CI: 3.289-4.016、3.611-4.377) were the risk factors for the detection of anxiety and depressive mood in secondary school students, and eating fresh fruits≥1 time/day(OR: 0.824、0.758,95% CI: 0.800-0.849、0.73-0.783), eating breakfast frequently(sometimes: OR: 0.843、0.715,95% CI: 0.781-0.910、0.661-0.773; daily: OR: 0.538、0.384,95% CI: 0.500-0.579、0.356-0.414), doing moderate to high-intensity exercise frequently(1-3 days/week: OR: 0.888、0.821,95% CI: 0.854-0.923、0.787-0.857; ≥4 days/week: OR: 0.931、0.848,95% CI: 0.893-0.971、0.810-0.887), and having a large number of physical education hours(2-3 sessions/week: OR: 0.826、0.859,95% CI: 0.801-0.853、0.829-0.890; ≥4 sessions/week: OR: 0.741、0.758,95% CI: 0.695-0.789、0.705-0.815) were the protective factors for the detection of anxiety and depressive protective factors for mood detection. Drinking sugary drinks≥1 time/day(OR: 1.198,95% CI: 1.122-1.279) and eating vegetables≥1 time/day(OR: 0.861,95% CI: 0.828-0.895) were independent risk factors and independent protective factors for the detection of depressed mood, respectively. The AUC of the Random Forest model predicting the risk of anxiety and depressed mood was 0.999 8 and 0.999 7, with a sensitivity of 99.53% and 99.67%, and a specificity of 99.47% and 98.98%, respectively. Being scolded by parents, Internet addiction and alcohol consumption were the common factors that had a greater degree of influence on anxiety and depression among secondary school students.

    Conclusion

    The detection rate of anxiety and depression among secondary school students in Shanxi Province is high, being scolded by parents, alcohol consumption and Internet addiction are the factors that have a greater influence on the occurrence of anxiety and depression, and the random forest model has a high predictive value.

  • Ming-yue DUAN, Wan-min HUANG, Dan-feng JIANG, Yan-fang DENG, Chao LIAO, Chun-liu LUO
    Modern Preventive Medicine. 2025, 52(2): 322-327.
    Objective

    To investigate the intrinsic relationships among family functioning, life events and insomnia in adolescents with depression.

    Methods

    A survey was conducted on 165 adolescents diagnosed with depression who were receiving treatment at a tertiary hospital in Guangzhou. The study utilized a general information questionnaire, Family APGAR Index, Insomnia Severity Index, and Adolescent Life Events Scale. Descriptive and correlation analyses were performed using SPSS, and mediation effects were tested using the Process plugin.

    Results

    The insomnia rate among adolescent depression patients was 77.58%. There was a significant positive correlation between insomnia and the total score of life events and its dimension factors (P<0.01), while insomnia showed a significant negative correlation with the total score of family functioning and its dimension factors (P<0.01). The results of the Bootstrap test indicate that family care, growth factors and cooperation play a partial mediating role between life events and insomnia in adolescent depression patients (β=0.019, 95% CI: 0.003-0.036; β= 0.013, 95% CI: 0.01-0.026; β= 0.011, 95% CI: 0.000-0.024), accounting for 15.45%, 10.57% and 8.94% of the total effect, respectively.

    Conclusion

    Adolescents with depression experience moderate to high levels of insomnia. Life events in adolescents with depression can directly affect insomnia, or indirectly influence it through family care.

  • Xia LUO, Xi-xia YANG, Zhu ZHU, Jian WU, Jie CHEN, Wen-wen YANG, Xiao-jing JIANG, Jing-jing YU
    Modern Preventive Medicine. 2025, 52(2): 349-354.
    Objective

    To understand the various metal elements content and distribution in crayfish sold in Deyang, and to initial determine the harm of hazardous metallic elements to residents in Deyang.

    Methods

    A total of 102 samples were collected in Deyang using a stratified random sampling approach, the samples was digested by microwave digestion,17 mineral elements and 7 harmful metal elements were detected using inductively coupled plasma optical emission spectroscopy (ICP-OES) and inductively coupled plasma mass spectrometry(ICP-MS).

    Results

    Mineral elements in all parts of the crayfish were detected and the content varies, in terms of total minerals, crayfish brain> crayfish intestine> crayfish gills> crayfish meat> crayfish hepatopancreas. For harmful metals, there was no exceedance in crayfish meat, As, Cu, Cd in crayfish hepatopancreas exceeded the standard rate of 97.0%, 2.97%, 27.7%, Hg, Pb, Cr did not exceed the standard, As, Cu, Pb, Cr and Al were all exceeded the standard in the non-edible parts by 2.17% to 100%. The enrichment pattern of all metal elements in crayfish in Deyang and Hubei was consistent, but the contents varied. In different sampling sessions, none of the harmful metal elements in crayfish meat exceeded the standard; As, Cu, Cd in crayfish hepatopancreas exceeded the standard rate of 2.8%-97%, and the rest of the elements did not exceed the standard. In different growth stages, except for As, there was no significant difference in the accumulation of hazardous metal elements between green and red crayfish.

    Conclusion

    Crayfish have a high mineral content and abundant nutrients, and local residents in Deyang City have a lower risk of heavy metal hazards in their daily intake of crayfish.

  • Zi-ying CHEN, Ming-xing NI, Jia-xuan LI, Yi-lin NIU, Hui-xian LI, Hai-qing ZHENG, Qing LI, Jia-mei LI, Hui-ying LIANG
    Modern Preventive Medicine. 2025, 52(2): 246-252.
    Objective

    To evaluate the associations between circulating monounsaturated fatty acids(cMUFAs) and cardiovascular-specific death using epidemiological methods.

    Methods

    This study included 36 254 patients with cardiovascular disease from the UK Biobank. Cox proportional hazards models were employed to examine the associations between cMUFAs and various fatalities, including cardiovascular death, ischaemic heart disease death, stroke death, cancer death, and all-cause death. Moreover, the study examined the dose-response relationship between cMUFAs and outcomes using quartiles, deciles, and restricted cubic splines. A subgroup analysis was conducted to validate the effects of cMUFAs on cardiovascular-specific deaths across different subgroups.

    Results

    A positive correlation was observed between cMUFAs and all-cause death (HR=1.556, 95% CI: 1.419-1.705), as well as CVD (HR=1.504, 95% CI: 1.261-1.794), IHD (HR=1.572, 95% CI: 1.265-1.953), and cancer death (HR=1.291, 95% CI: 1.109-1.502). However, no significant association was found between cMUFAs and stroke death (P=0.582). The study revealed the existence of non-linear relationships between cMUFAs and cardiovascular-specific death. Subgroup analyses indicated that the association with all-cause death was more pronounced in females and current smokers. Furthermore, individuals aged over 50 years demonstrated a more pronounced correlation with IHD death.

    Conclusion

    In patients with cardiovascular disease, elevated levels of cMUFAs are associated with an increased risk of CVD death, IHD death, cancer death, and all-cause death. This association demonstrates a non-linear correlation trend.