For the experimental research of Xinjiang oilfield, all kinds of research work can not be separated from experiments. As an important place of scientific and technological research and development, the quality and level of scientific and technological research and development are directly affected by the management of the laboratory, therefore, it is of great significance to do a good job in the management of the laboratory. According to the actual situation of laboratory work, this paper summarizes the experience of laboratory management, and puts forward and implements the innovation mechanism of safety autonomous management in the course of experimental research from the aspects of creating safety concept culture and establishing standardized management mode, etc., the purpose of this paper is to promote the high-quality and high-efficiency of scientific research and production by improving the management of laboratories in oil-field scientific research units, it provides guarantee for Xinjiang oilfield to create greater economic benefits.

Multi-angle phased array ultrasonic technology has important application value in fatigue crack detection of complex structural parts. In this paper, the basic principle of the technique is summarized first, and then the main difficulties in fatigue crack detection of complex structural parts are analyzed, including complex geometric structure interference, quantitative crack characteristics evaluation and environmental factors. To address these challenges, innovative solutions such as deep learning signal processing, multi-parameter feature extraction and adaptive detection strategies are proposed. This study provides a new idea and direction for the further development of fatigue crack detection technology for complex structural parts.

Objective To systematically evaluate the applicationpotential of ${35}\mathrm{{kV}}$ modified polypropylene in the field of wire and cable. Methods Themechanical properties, thermal properties and electrical insulationproperties of the material were investigated by differential scanningcalorimetry (DSC), tensile test and electrical property evaluation.Results The modified polypropylene showed excellent mechanical strengthand thermal stability, and the performance of electrical insulation alsomet the high standards of industrial applications. Conclusion Thesystematic test of this study not only provides a scientific basis forfurther modification and optimization of polypropylene materials, butalso lays a solid foundation for its future market promotion, andprovides important theoretical and practical value for promoting thetechnological progress of wire and cable materials and realizing thedevelopment of environmentally friendly materials.

Objective By analyzing the original detection results of urine organic acids in Changchun, Jilin Province, this study aims to explore the incidence of genetic metabolic diseases related to urine organic acid detection projects in Changchun, Jilin Province, and analyze the detection data. Methods Gas chromatography-mass spectrometry (GC-MS) was used to analyze the results of the urine organic acid detection project submitted by Jilin Jincheng Medical Co., Ltd. in Changchun, Jilin Province from January 2019 to May 2023. Results there were 83 cases of positive diseases in the initial screening, with a positive rate of 3.93%. Among them, there were 43 cases of methylmalonic acidemia with a positive rate of 51.81%, 10 cases of hyperphenylalaninemia with a positive rate of 12.05%, 6 cases of glutaric acidemia type 1 with a positive rate of 7.23%, 5 cases of Citrin protein deficiency with a positive rate of 6.02%, 5 cases of propionaemia with a positive rate of 6.02%, 4 cases of maple diabetes with a positive rate of 4.82%, and 10 cases of other diseases with a positive rate of 12.05%. Conclusion Organic acid metabolism disease, also known as organic aciduria, is the most common genetic metabolic disease. Urine organic acid screening is an effective method for preventing and treating certain genetic metabolic diseases after birth, among which methylmalonic acidemia is the most common genetic metabolic disease with abnormal organic acid metabolism. In order to improve the survival rate and quality of life of children, people must raise awareness, detect, diagnose and treat them early.

Objective To evaluate the early diagnosis and prognosis ofmultiple myeloma (MM) by gene sequencing technology. Methods 68 patientswith MM admitted from May 2020 to May 2024 were randomly divided intoobservation group (34 cases) and control group (34 cases). Patients inthe observation group received early diagnosis and prognosis assessmentrelated to gene sequencing, while those in the control group receivedtraditional diagnosis methods. Results In the early diagnosis accuracy,the number of correct and wrong diagnoses in the observation group was31 cases and 3 cases, respectively, and the diagnosis accuracy was91.2%. The number of correct and wrong diagnoses in control group was 23cases and 11 cases, respectively, the diagnostic accuracy was ${67.62}\%$ , and the observation group washigher $\left({P <{0.05}}\right)$ .In the observation group, the number of ISS stage I, ISS Stage II, ISSStage III and high-risk mutation detection were 10 cases, 15 cases, 9cases and 12 cases, respectively, and the accuracy of prognosisassessment was 85.3%. In the control group, there were 8 cases of ISSstage I, 13 cases of ISS stage II, 13 cases of ISS stage III and 8 casesof high-risk mutation detection, respectively. The accuracy of prognosisassessment was ${67.6}\%$ , and theaccuracy of prognosis assessment in the observation group wassignificantly higher than that in the control group. The overallsurvival rate and progression-free survival rate were 94.1% and 70.6% inthe observation group, and 82.4% and 52.9% in the control group,respectively, which were higher in the observation group $\left({P <{0.05}}\right)$ . Conclusion Gene sequencing technology is helpful to the early detection of MM andthe formulation of personalized treatment plan, improve the survivalrate and quality of life of patients, and has the value of applicationand promotion in clinical practice.

Aiming at the common problems existing in the scientific research laboratories of universities, such as the low level of information management, the unclear responsibility of laboratory management, the lack of equipment maintenance in the later stage and the low utilization ratio of instruments and equipment, this study proposes a"Flexible" laboratory management mechanism to solve the bottleneck problem of laboratory management. “Flexible management" is to optimize all kinds of existing soft and hard resources into a "Flexible" whole by establishing an information-based management platform, the invention solves the problems of low utilization rate of laboratory and instrument equipment, repeated purchase of the same kind of equipment, and difficulty in late-stage maintenance of equipment. Therefore, it is an inexorable trend of engineering laboratory construction to construct an efficient and extensible flexible mechanism.

Objective In this paper, aiming at the shortcomings of the industry standard of GA/T 1522-2018 Forensic Science Shooting Residue Inspection Scanning Electron Microscopy/X-Ray Spectroscopy, which only provides a few reference characteristic forms and has limited reference such as no reference energy spectrum diagram. Through simulation experiments, a practical reference is provided for the inspection of shooting residues. Methods Taking the shooting of 7.62 mm Type 51 bullet with Type 54 pistol as an example, shooting experiments of naked and clothed human bodies were simulated, and the collection, preparation and inspection steps of shooting residues, typical morphology and composition characteristics of shooting residues were explained in detail. Results Through simulation experiments, the scanning electron microscope morphology and energy spectrum characteristics of the shooting residues produced by the Type 54 pistol shooting the 7.62 mm Type 51 bullet were obtained. Conclusion Each gun and bullet combination has its own specific SEM morphology and energy spectrum characteristics.

Objective To compare the application effects of different influenza virus detection methods. Methods 100 influenza patients admitted to a certain hospital from January 2021 to June 2023 were randomly divided into an observation group (fluorescence RT-PCR test) and a control group (colloidal gold immunochromatographic test), with 50 patients in each group. Results Compared with the control group, the observation group had a higher positive rate of testing (P&lt;0.05). Conclusion Using fluorescence RT-PCR to detect influenza virus can achieve higher detection results and improve the positivity rate of the test.

Objective To explore the clinical application value of combined detection of echocardiography, dynamic electrocardiogram, and plate exercise test in the diagnosis of coronary heart disease. Methods 70 suspected coronary heart disease patients were selected and subjected to plate exercise test, dynamic electrocardiogram, echocardiography, and coronary angiography. Analyze the diagnostic performance of each method through ROC curve, and calculate sensitivity, specificity, and AUC values. Results The individual detection AUC values of the three methods were 0.796 (plate exercise test), 0.737 (dynamic electrocardiogram), and 0.773 (echocardiogram), respectively, and the combined detection AUC was 0.826. Conclusion Combined detection can significantly improve the diagnostic accuracy of coronary heart disease, with higher sensitivity and specificity than single detection. It is recommended to widely apply it in clinical practice.

Objective To evaluate of uncertainty in the determination of residual cyclopropamide in animal food by high-performance liquid chromatography. Methods The sample was repeatedly extracted by the mixture of Trichloroacetic acid and acetonitrile. The supernatant was degreased with n-hexane, and then concentrated by rotating evaporation in a water bath. The mixture of trichloroacetic acid and acetonitrile was redissolved, and then purified by a mixed cation exchange solid phase extraction column. After separation by an amino chromatographic column, acetonitrile water was used as the mobile phase for isocratic elution. The residue of cyclopromazine in animal food was quantitatively determined by diode array detector and external standard method. According to the JJF 1135-2005 Chemical Analysis Measurement Uncertainty Assessment and JJF 1059.1-2012 Measurement Uncertainty Assessment and Representation, the uncertaintygenerated during the entiretesting process includes weighing, standard, standard working curve formulation, standard curve fitting, sample measurement repeatability, instrument and standard recovery rate, and the uncertainty introduced by each factor is calculated, and finally theexpansionuncertainty is obtained. Results When the detection result of cyromazine in chicken was 19.8 µg/kg, with an expanded uncertainty of 3.2 µg/kg. Conclusion The main factors affecting uncertainty are the determination of standard, samples, the preparation of standard curves and the fitting of standard curves.