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Application of Modified Liuwei Dihuang Pill(六味地黄丸加减)in Muscle Atrophy of Patients with Diabetes Peripheral Neuropathy
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Haiyan FENG, Yuehong LI, Yunfeng LIU, Xiaojuan FENG, Shaoqun LUAN
Chinese Archives of Traditional Chinese Medicine | 2025, 43(10) : 45 - 48
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Chinese Archives of Traditional Chinese Medicine | 2025, 43(10): 45-48
• Target on National Project •
Application of Modified Liuwei Dihuang Pill(六味地黄丸加减)in Muscle Atrophy of Patients with Diabetes Peripheral Neuropathy
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Haiyan FENG, Yuehong LI, Yunfeng LIU, Xiaojuan FENG, Shaoqun LUAN
Affiliations
  • Xingtai People’s Hospital,Xingtai 054000,Hebei,China
Published: 2025-10-10 doi: 10.13193/j.issn.1673-7717.2025.10.009
Outline
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Objective

To analyze the effect of Liuwei Dihuang Pill(六味地黄丸)on muscle atrophy in patients with diabetic peripheral neuropathy.

Methods

A total of 80 patients with diabetic peripheral neuropathy treated in the hospital from November 2022 to March 2024 were included in the study.They were divided into two groups by random number table method.Forty patients in the control group were treated with conventional western medicine,and the other 40 patients in the observation group were treated with Liuwei Dihuang Pill on the basis of control group.The treatment effect,blood glucose change and nerve conduction velocity change of Toronto Clinical Scoring system(TCSS)were compared between the two groups.

Results

The total effective rate of the observation group was 95.0%(38/40),which was much higher than that of the control group(72.5%,29/40),and the difference was significant(P<0.05).After treatment,TCSSscore and blood glucose index of the observation group were lower than those of the control group(P<0.05).After treatment,motor nerve conduction velocity(MNCV)and sensory nerve conduction velocity(SNCV)of common peroneal nerve and median nerve in the observation group were higher than those in the control group(P<0.05).After treatment,the average latency,dispersion and abnormality rate of F waves in the median nerve,ulnar nerve,common peroneal nerve and tibial nerve in the observation group were lower than those in the control group(P<0.05).

Conclusion

The application of Liuwei Dihuang Pill in the treatment of diabetic peripheral neuropathy can effectively improve the numbness,pain and other related symptoms,reduce the severity of neuropathy,increase the nerve conduction speed and relieve the muscle atrophy,and plays a positive role in the prognosis of patients.

diabetic peripheral neuropathy  /  muscular atrophy  /  Liuwei Dihuang Pill(六味地黄丸)  /  nerve conduction velocity
冯海燕, 李月红, 刘云峰, 冯晓娟, 栾绍群. 六味地黄丸加味对糖尿病周围神经病变患者肌肉萎缩期的应用研究. 中华中医药学刊, 2025 , 43 (10) : 45 -48 . DOI: 10.13193/j.issn.1673-7717.2025.10.009
Haiyan FENG, Yuehong LI, Yunfeng LIU, Xiaojuan FENG, Shaoqun LUAN. Application of Modified Liuwei Dihuang Pill(六味地黄丸加减)in Muscle Atrophy of Patients with Diabetes Peripheral Neuropathy[J]. Chinese Archives of Traditional Chinese Medicine, 2025 , 43 (10) : 45 -48 . DOI: 10.13193/j.issn.1673-7717.2025.10.009
Year 2025 volume 43 Issue 10
46
23
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doi: 10.13193/j.issn.1673-7717.2025.10.009
  • Online Date:2026-10-30
  • Published:2025-10-10
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    Xingtai People’s Hospital,Xingtai 054000,Hebei,China
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表12种不同金属材料的力学参数
科
Family
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Number of
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Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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