Chronic atrophic gastritis（CAG）is a common disease of the digestive system，and its incidence ranks first among various gastric diseases，with epigastric fullness，pain，pantothenic acid，nausea and vomiting as the main clinical manifestations，and the occurrence of this disease is related to Helicobacter pylori（Hp）infection，dietary and environmental factors，autoimmunity，bile reflux，etc.，among which Hp infection is the most. At present，the treatment of CAGin Western medicine is mainly based on the symptomatic treatment of multi-drug combination，although it can achieve certain effects，but the adverse reactions are obvious，and long-term use is easy to develop drug resistance. Traditional Chinese medicine（TCM）has the advantages of multicomponent，multi-target and multi-channel，and has significant efficacy in the prevention and treatment of CAG. This article summarized and sorted out the theoretical basis and mechanism of Banxia Xingxin Decoction in the treatment of CAGby searching and reviewing the relevant literature of CNKI，Wanfang，PubMed and other databases，in order to provide an important reference and theoretical basis for Banxia Xiexin Decoction in the prevention and treatment of CAG.