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Outline
Yinyanghuo（Epimedii Folium）is a traditional tonic traditional Chinese medicine. It has significant biological functional activity and a wide range of pharmacological effects on many major organs and tissues of the human body. Themain chemical constituents of Yinyanghuo（Epimedii Folium）are flavonoids，lignans，alkaloids，volatile oils and other trace elements. Flavonoids are the main active ingredients and have significant immunomodulatory effects on the body. The immunomodulatory effects of flavonoids such as icariin（ICA），icaritin（ICT），dehydrated icariin（AHI），icariside I（ICA I），icariin polysaccharide（EPS）and total flavonoids of icariin（EFC）have been widely reported in recent years. A number of studies have shown that the above components have significant regulatory effects on immune organs，immune cells（includingmacrophages，T lymphocytes，B lymphocytes，NK cells，LAK cells，CD3AK cells，etc.），immune factors and tumor immune microenvironment. In recent years，with the continuous deepening of clinical observation and experimental research on the regulation of immune function by Yinyanghuo（Epimedii Folium），it has provided a scientific basis for improving the immune function of the body by traditional Chinese medicine. In this paper，the research status of Yinyanghuo（Epimedii Folium）regulating immune function was reviewed in order to provide reference for the study of the immunomodulatory effect of Yinyanghuo（Epimedii Folium）or other tonic Chinese medicines.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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