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Outline
Danggui（Angelicae Sinensis Radix）-Huangqi（Astragali Radix）is one of the commonly used Chinese medicine prescriptions，which has a clear compatibility significance for the use of traditional Chinese medicine，and is one of the most representative drug combinations.It can not only be a formula by itself，but also be used as a combination of clinical basic drugs，so it has always been paid attention to by various doctors.Modern pharmacological studies have also shown that Danggui（Angelicae Sinensis Radix）-Huangqi（Astragali Radix）has a good effect on promoting hematopoietic production，inhibiting tumor growth and proliferation，protecting cardiovascular and cerebrovascular vessels，and regulating the immune system，and is often used in clinical treatment of vascular diseases and immunosuppression in tumor patients.Inflammatory factors mediated by nuclear transcription factor-κB（NF-κB）related signaling pathways play an important role in the formation and progression of disease.Studies have shown that TCM monomer and single drug can mediate the reduction of inflammatory response through NF-κB signaling pathway，including regulating the expressions of interleukin（IL）family，cycloceuxy-2（COX-2），vascular endothelial growth factor（VEGF），matrix protease（MMPs）family and other factors，and play an anti-inflammatory role in inhibiting cell adhesion and proliferation.In view of this，the pharmacology and efficacy of Danggui（Angelicae Sinensis Radix）-Huangqi（Astragali Radix）and the regulation of NF-κB signaling pathway were reviewed in this paper，so as to provide relevant reference for future clinical application.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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