To study curative effect of Banxia Xiexin Decoction（半夏泻心汤）on gastric epithelial dysplasia and its influence on immune function and gastric mucosa inflammatory reaction.

Eighty cases with gastric epithelial dysplasia（dampness-heat syndrome of spleen and stomach）were divided into the control group and the study group with 40 cases in each by digital table method.The control group was treated with conventional western medicine，and the observation group was treated with Banxia Xiexin Decoction.The course was12 weeks.The changes of TCM syndrome scores，immune function and gastric mucosal inflammation were observed before and after treatment.

There was no significant difference in fullness，stomachache，fatigue，loose stool，belching，lethargy and lack of thirst between the two groups before treatment（P>0.05）.After treatment，the score decreased（P<0.001），and the degree of decline in the observation group was greater than that in the control group（P<0.001）.There was no significant difference in the levels of CD⁺₃，CD⁺₄ or CD⁺₈ between the two groups before treatment（P>0.05），and the levels of CD⁺₃ and CD⁺₄ were higher than those before treatment（P<0.001），and the increases in the observation group were greater than those in the control group（P<0.001）.There was no significant difference in serum levels of interleukin-6（IL-6），interleukin-2（IL-2），interleukin-17（IL-17）or tumor necrosis factor-α（TNF-α）between the two groups before treatment（P>0.05），and the levels of IL-6，IL-17 and TNF-αwere decreased compared with those before treatment（P<0.001）.The decrease of IL-2 in the observation group was greater than that in the control group（P<0.001），and the increase of IL-2 in the observation group was greater than that in the control group（P<0.001）.The therapeutic effect of the observation group was better than that of the control group（P<0.05）.

Banxia Xiexin Decoction in the treat-ment of gastric mucosal dysplasia（dampness-heat syndrome of spleen and stomach）can help to alleviate disease-related symptoms，improve the immune function，inhibit the inflammatory response and improve the therapeutic effect.