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Overview of Anti-Atherosclerosis Mechanism of Xiebai（Allii Macrostemonis Bulbus）and Its Classical Compatibility
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Yixin ZHANG1, Zhentao WANG1, 2, Yueqing QIU1, Hongbo CHANG2
Chinese Archives of Traditional Chinese Medicine | 2025, 43(6) : 46 - 51
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Chinese Archives of Traditional Chinese Medicine | 2025, 43(6): 46-51
• Target on National Project •
Overview of Anti-Atherosclerosis Mechanism of Xiebai（Allii Macrostemonis Bulbus）and Its Classical Compatibility
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Yixin ZHANG1, Zhentao WANG1, 2, Yueqing QIU1, Hongbo CHANG2
Affiliations
  • 1.Second Clinical Medical College，Henan University of Chinese Medicine，Zhengzhou 450011，Henan，China
  • 2.Henan Provincial Hospital of Traditional Chinese Medicine，The Second Affiliated Hospital of Henan University of Chinese Medicine，Zhengzhou 450053，Henan，China
Published: 2025-06-10 doi: 10.13193/j.issn.1673-7717.2025.06.008
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Atherosclerosis（AS）is a chronic vascular disease，which is the pathological basis of many cardiovascular and cerebrovascular diseases.The rupture of atherosclerotic plaque is prone to serious cardiovascular and cerebrovascular events.The formation mechanism of AS is complex，mainly involving endothelial damage and dysfunction，lipid metabolism disorder deposition，inflammatory response，platelet aggregation and oxidative stress.Xiebai（Allii Macrostemonis Bulbus）is an essential medicine used in the Treatise on Cold Damage and Miscellaneous Diseases to treat chest obstruction and heart pain.It has the functions of dredging Yang and dispersing mass，and promoting Qi circulation to relieve stagnation.Modern research has shown that Xiebai（Allii Macrostemonis Bulbus）contains multiple effective natural active ingredients that work synergistically on multiple signaling pathways.This article reviewed the mechanism of Xiebai（Allii Macrostemonis Bulbus）and its classic compatibility in anti-AS from multiple aspects such as regulating vasodilation function，anti-inflammation，antioxidant stress，anti-platelet aggregation and lowering lipids，by reviewing the relevant literature.This provided a reference for expanding its application scope，fully exerting its therapeutic effect，and developing clinical drugs and future basic research directions.

Xiebai（Allii Macrostemonis Bulbus）  /  atherosclerosis  /  mechanism  /  summary
张译心, 王振涛, 邱月清, 常红波. 薤白及其经典配伍抗动脉粥样硬化作用机制的概述. 中华中医药学刊, 2025 , 43 (6) : 46 -51 . DOI: 10.13193/j.issn.1673-7717.2025.06.008
Yixin ZHANG, Zhentao WANG, Yueqing QIU, Hongbo CHANG. Overview of Anti-Atherosclerosis Mechanism of Xiebai（Allii Macrostemonis Bulbus）and Its Classical Compatibility[J]. Chinese Archives of Traditional Chinese Medicine, 2025 , 43 (6) : 46 -51 . DOI: 10.13193/j.issn.1673-7717.2025.06.008
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Year 2025 volume 43 Issue 6
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doi: 10.13193/j.issn.1673-7717.2025.06.008
  • Online Date：2026-10-30
  • Published：2025-06-10
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    1.Second Clinical Medical College，Henan University of Chinese Medicine，Zhengzhou 450011，Henan，China
    2.Henan Provincial Hospital of Traditional Chinese Medicine，The Second Affiliated Hospital of Henan University of Chinese Medicine，Zhengzhou 450053，Henan，China
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表12种不同金属材料的力学参数
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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