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Research Progress of Chemical Composition，Pharmacological Action and Predictive Analysis of Quality Markers of Yimucao（Leonuri Herba）
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Tian’ai LI1, Yishuo WANG1, 2, Ying WANG1, Changfeng ZHANG1, Tian’ai LU1, Rui LOU1
Chinese Archives of Traditional Chinese Medicine | 2025, 43(4) : 230 - 247
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Chinese Archives of Traditional Chinese Medicine | 2025, 43(4): 230-247
• Platform of Provincial Project •
Research Progress of Chemical Composition，Pharmacological Action and Predictive Analysis of Quality Markers of Yimucao（Leonuri Herba）
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Tian’ai LI1, Yishuo WANG1, 2, Ying WANG1, Changfeng ZHANG1, Tian’ai LU1, Rui LOU1
Affiliations
  • 1.College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
  • 2.Henan Province Traditional Chinese Medicine Production Integration Engineering Technology Research Center, Zhengzhou 450046, Henan, China
Published: 2025-04-10 doi: 10.13193/j.issn.1673-7717.2025.04.040
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Yimucao（Leonuri Herba）has a long history of drug use as a medicine for promoting blood circulation and regulating menstrual cycle. It mainly contains alkaloids，flavonoids，diterpenes and other chemical components，and has pharmacological effects such as anti-oxidation，anti-apoptosis，anti-inflammatory and analgesic. This paper summarized the chemical composition，pharmacological action，clinical application and safety evaluation of Yimucao（Leonuri Herba）. The quality marker（Qmarker）of Yimucao（Leonuri Herba）was predicted and analyzed from the aspects of plant affinity，traditional medicinal properties and efficacy，component measurability，different origin，harvesting period and different medicinal parts，processing and chemical composition related characteristics，pharmacokinetics，modern clinical use，etc. It is preliminatively speculated that leonurine hydrochloride，stachydrine hydrochloride，stachydrine，leonurine，rutin，quercetin，syringic acid，hyperoside and isoquercitrin are used as Q-markers to provide reference for the study of Q-markers and the establishment of systematic quality control system of Yimucao（Leonuri Herba）.

Yimucao（Leonuri Herba）  /  chemical constituents  /  pharmacological effects  /  clinical application  /  safety evaluation  /  quality markers
李天爱, 王一硕, 王颖, 张昌锋, 鲁天爱, 娄瑞. 益母草化学成分、药理作用研究进展及质量标志物（Q-Marker）预测分析. 中华中医药学刊, 2025 , 43 (4) : 230 -247 . DOI: 10.13193/j.issn.1673-7717.2025.04.040
Tian’ai LI, Yishuo WANG, Ying WANG, Changfeng ZHANG, Tian’ai LU, Rui LOU. Research Progress of Chemical Composition，Pharmacological Action and Predictive Analysis of Quality Markers of Yimucao（Leonuri Herba）[J]. Chinese Archives of Traditional Chinese Medicine, 2025 , 43 (4) : 230 -247 . DOI: 10.13193/j.issn.1673-7717.2025.04.040
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Year 2025 volume 43 Issue 4
52
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doi: 10.13193/j.issn.1673-7717.2025.04.040
  • Online Date：2026-10-30
  • Published：2025-04-10
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    1.College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
    2.Henan Province Traditional Chinese Medicine Production Integration Engineering Technology Research Center, Zhengzhou 450046, Henan, China
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表12种不同金属材料的力学参数
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小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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