To explore the effect of Jianpi Ziyin Decoction(健脾滋阴汤)combined with atorvastatin on the improvement of traditional Chinese medicine syndrome characteristics,hemorrheology and electrocardiogram in patients with coronary heart disease microcirculation disorders.
A hundred patients with coronary heart disease microcirculatory disorder of Qi deficiency and blood stasis syndrome were enrolled in the hospital,and the patients were randomly divided into an observation group and a control group according to the random number table method,50 cases in each.The control group was given atorvastatin calcium tablets,and the observation group was given Jianpi Ziyin Decoction on the basis of the treatment plan of the control group.After treatment,the clinical efficacy,TCM clinical symptom scores,microcirculatory function,hemorrheology,blood lipid levels and electrocardiogram efficacy of the two groups were observed before and after treatment.
After treatment,the total effective rate of the observation group was 92.00%,which was significantly higher than that(74.00%)in the control group(P<0.05).After treatment,the TCM clinical symptom scores of the two groups were significantly improved compared with those before treatment(P<0.05).The symptom scores of the observation group in terms of chest tightness,chest pain,fatigue,palpitations,shortness of breath,insomnia and night sweats were significantly better than those in the control group(P<0.05).The coronary flow reserve(CFR)of the two groups after treatment was higher than that before treatment.There was a significant improvement(P<0.05),and the CFR improvement of the observation group was significantly better than that the control group(P<0.05).After treatment,the index of microcirculatory(IMR)of both groups decreased significantly compared with those be-fore treatment(P<0.05)and the index of the observation group was significantly better than that of the control group(P<0.05).After treatment,the blood rheology indexes of both groups were significantly lower than those before treatment(P<0.05).The whole blood viscosity high shear,whole blood viscosity low shear,platelet aggregation rate and red blood cell aggregation index in the observation group were significantly better than those in the control group(P<0.05).The blood lipid levels in both groups after treatment were significantly improved compared with those before treatment(P<0.05).The observation group had lower levels of total cholesterol(TC),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C)and highdensity lipoprotein cholesterol(HDL-C)than the control group(P<0.05).After treatment,the total ST segment effective rate of the observation group was 92.00%,which was significantly higher than that(70.00%)in the control group(P<0.05).After treatment,the total effective rate of T-band in the observation group was 90.00%,which was significantly higher than that in the control group(78.00%)(P<0.05).
Jianpi Ziyin Decoction combined with atorvastatin can effectively improve the clinical treatment effect,the clinical symptoms and microcirculation function,reduce the blood rheology and blood lipid levels and improve the electrocardiogram of patients with coronary heart disease.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |