Ferroptosis,a pattern of cell apoptosis driven by iron-dependent lipid peroxidation,plays an important role in the complex pathological process of cerebral ischemia-reperfusion injury. This type of injury usually occurs during the recovery of blood flowing after cerebral ischemia,when the brain tissue undergoes a more severe secondary injury. In a series of complex physiological reactions,multiple mechanisms such as oxidative stress,excessive intracellular calcium concentration and inflammation work together,ferroptosis is a part of them which cannot be ignored. Recent studies have shown that certain LncRNAs can significantly affect the process of cerebral ischemia-reperfusion injury by influencing the expressions of ferroptosis-related genes. Some LncRNAs play a role in the process of apoptosis after cerebral ischemia-reperfusion injury by regulating the expression of genes related to autophagy. The research on how LncRNA affects ferroptosis in cerebral ischemia-reperfusion injury is still in its initial stage,but the research value and application potential in this field have already emerged. In the future,we can further explore the mechanisms by which LncRNAs regulate ferroptosis and strive to discover more LncRNAs related to ferroptosis,in order to find new methods and ways for treating cerebral ischemia-reperfusion injury.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |