To study the intervention effect of Fuyuan Huoxue Decoction(复元活血汤)combined with Dahuang Zhechong Pill(大黄䗪虫丸)on cancer-induced fatigue of breast cancer under the guidance of exhaustion and dry blood theory.
A total of 240 patients diagnosed as breast cancer fatigue were divided into two groups according to the random number table,120 patients in the reference group were treated with chemotherapy and corresponding symptomatic treatment,and 120 patients in the study group were treated with Fuyuan Huoxue Decoction combined with Dahuang Zhechong Pill. The clinical efficacy of the two groups was observed and compared.
Compared with that of the reference group,the total effective rate of the study group was 95.83%(115/120),which was higher than that of the reference group(75.00%,90/120),and the difference was statistically significant(P<0.05). After treatment,the fatigue degree of the study group was lower than that of the reference group,the difference was statistically significant(P<0.05). After treatment,the levels of CD3+and CD4+in the study group were higher than those in the reference group,and the level of CD8+was lower than that in the reference group,with statistical significance(P<0.05). After treatment,compared with those of the reference group,the serum levels of TNF-αand IL-4 in the study group were lower than those in the reference group,and the levels of IL-2 and IFN-γwere higher in the study group with statistical significance(P<0.05).
The combined treatment of Fuyuan Huoxue Decoction and Dahuang Zhechong Pill can effectively relieve the symptoms of cancer fatigue,reduce the inflammatory response and improve the immune function of the body,with high clinical application value.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |