Full
Outline
To investigate the therapeutic effect of exercise combined with Chishao（Paeoniae Radix Rubra）on the rat model of non-alcoholic fatty liver disease（NAFLD）.
Forty male rats were divided into the blank control group，the model group，the exercise group，the Chishao（Paeoniae Radix Rubra）group and the exercise combined with Chishao（Paeoniae Radix Rubra）group. Except the blank control group，the other groups were continuously fed with a high-fat diet for 4 weeks，the blood of the rats was collected and the concentrations of alanine aminotransferase（ALT），aspartate aminotransferase（AST），triglyceride（TC），total cholesterol（TG），low-density lipoprotein（LDL-C），high-density lipoprotein（HDL-C），free fatty acid（FFA）and leptin were measured and the body weight and liver weight of the rats were measured.
Feeding with a highfat diet for 4 consecutive weeks could form an animal model of NAFLD rats. In the Chishao（Paeoniae Radix Rubra）group and the exercise combined with Chishao（Paeoniae Radix Rubra）group，the contents of ALT，AST，TC，TG，LDL-C and FFA in the rat serum were significantly lower than those in the model group（P<0.05）. The contents of HDL-Cand leptin in the rat serum in the Chishao（Paeoniae Radix Rubra）group and the exercise combined with Chishao（Paeoniae Radix Rubra）group were significantly higher than those in the model group（P<0.05）.
Chishao（Paeoniae Radix Rubra）can reduce the contents of ALT，AST，TC，TG，LDL-Cand FFA，and increase the contents of HDL-C and leptin to treat NAFLD rats.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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